Incidental Mutation 'R0671:Eml6'
| ID |
61463 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Eml6
|
| Ensembl Gene |
ENSMUSG00000044072 |
| Gene Name |
echinoderm microtubule associated protein like 6 |
| Synonyms |
2900083P10Rik, C230094A16Rik |
| MMRRC Submission |
038856-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.228)
|
| Stock # |
R0671 (G1)
|
| Quality Score |
175 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
29693048-29976033 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 29755065 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 903
(D903E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000051080
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000058902]
|
| AlphaFold |
Q5SQM0 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000058902
AA Change: D903E
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000051080
Gene: ENSMUSG00000044072
AA Change: D903E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
36 |
47 |
N/A |
INTRINSIC |
|
WD40
|
49 |
91 |
1.79e-1 |
SMART |
|
WD40
|
94 |
136 |
1.42e-4 |
SMART |
|
WD40
|
139 |
178 |
5.31e-4 |
SMART |
|
WD40
|
184 |
224 |
8.84e1 |
SMART |
|
WD40
|
225 |
263 |
3.75e-4 |
SMART |
|
WD40
|
313 |
353 |
4.69e-5 |
SMART |
|
WD40
|
356 |
394 |
2.22e0 |
SMART |
|
WD40
|
397 |
436 |
1.72e0 |
SMART |
|
WD40
|
505 |
546 |
1.7e2 |
SMART |
|
WD40
|
552 |
592 |
4.55e-3 |
SMART |
|
low complexity region
|
613 |
625 |
N/A |
INTRINSIC |
|
Pfam:HELP
|
653 |
715 |
1.9e-22 |
PFAM |
|
WD40
|
716 |
757 |
9.24e-1 |
SMART |
|
WD40
|
760 |
802 |
6.53e-4 |
SMART |
|
WD40
|
805 |
844 |
2.98e-1 |
SMART |
|
WD40
|
856 |
891 |
8.52e1 |
SMART |
|
WD40
|
892 |
929 |
2.09e-2 |
SMART |
|
WD40
|
986 |
1026 |
1.18e-1 |
SMART |
|
WD40
|
1032 |
1068 |
3.44e0 |
SMART |
|
WD40
|
1071 |
1111 |
2.58e-1 |
SMART |
|
WD40
|
1180 |
1221 |
9.24e-1 |
SMART |
|
WD40
|
1227 |
1267 |
3.85e-1 |
SMART |
|
low complexity region
|
1280 |
1291 |
N/A |
INTRINSIC |
|
Pfam:HELP
|
1329 |
1402 |
5e-15 |
PFAM |
|
WD40
|
1404 |
1447 |
2.66e0 |
SMART |
|
WD40
|
1450 |
1492 |
1.85e0 |
SMART |
|
WD40
|
1495 |
1534 |
2.97e0 |
SMART |
|
WD40
|
1543 |
1582 |
7.1e1 |
SMART |
|
WD40
|
1584 |
1629 |
9.51e1 |
SMART |
|
WD40
|
1675 |
1715 |
3.05e-4 |
SMART |
|
WD40
|
1718 |
1758 |
8.84e1 |
SMART |
|
WD40
|
1759 |
1798 |
7.16e-1 |
SMART |
|
WD40
|
1869 |
1910 |
1.53e1 |
SMART |
|
WD40
|
1916 |
1956 |
4.62e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000109452
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000169980
|
| Meta Mutation Damage Score |
0.1306 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.9%
- 10x: 97.7%
- 20x: 96.1%
|
| Validation Efficiency |
99% (125/126) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 115 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700067K01Rik |
T |
C |
8: 84,729,637 (GRCm39) |
|
probably benign |
Het |
| A530064D06Rik |
G |
A |
17: 48,473,824 (GRCm39) |
T31I |
probably benign |
Het |
| Abca17 |
A |
G |
17: 24,500,223 (GRCm39) |
F1323L |
probably benign |
Het |
| Abcf3 |
T |
A |
16: 20,369,237 (GRCm39) |
N206K |
probably damaging |
Het |
| Adam10 |
A |
G |
9: 70,673,223 (GRCm39) |
|
probably benign |
Het |
| Adamtsl3 |
A |
T |
7: 82,172,390 (GRCm39) |
Q451L |
probably damaging |
Het |
| Adgrl3 |
T |
A |
5: 81,708,752 (GRCm39) |
I413N |
probably benign |
Het |
| Asb18 |
G |
T |
1: 89,920,893 (GRCm39) |
A128E |
probably damaging |
Het |
| Atf7ip2 |
T |
C |
16: 10,059,743 (GRCm39) |
S428P |
possibly damaging |
Het |
| Atp8b5 |
G |
T |
4: 43,291,672 (GRCm39) |
C15F |
possibly damaging |
Het |
| Bahcc1 |
A |
G |
11: 120,178,146 (GRCm39) |
E2235G |
probably damaging |
Het |
| Blnk |
G |
T |
19: 40,926,111 (GRCm39) |
S330* |
probably null |
Het |
| Bpnt1 |
T |
G |
1: 185,088,808 (GRCm39) |
N319K |
probably benign |
Het |
| Brip1 |
G |
A |
11: 86,043,493 (GRCm39) |
T357I |
possibly damaging |
Het |
| Cadm1 |
T |
A |
9: 47,725,104 (GRCm39) |
D288E |
probably benign |
Het |
| Calcoco2 |
A |
G |
11: 95,998,354 (GRCm39) |
V23A |
probably damaging |
Het |
| Cand2 |
G |
A |
6: 115,780,766 (GRCm39) |
E1217K |
probably damaging |
Het |
| Ccdc154 |
G |
T |
17: 25,386,259 (GRCm39) |
|
probably benign |
Het |
| Cdk12 |
T |
C |
11: 98,120,935 (GRCm39) |
|
probably benign |
Het |
| Clec4a3 |
A |
G |
6: 122,930,993 (GRCm39) |
|
probably null |
Het |
| Cpne2 |
T |
A |
8: 95,274,970 (GRCm39) |
|
probably benign |
Het |
| Cyfip1 |
T |
C |
7: 55,573,710 (GRCm39) |
|
probably null |
Het |
| Cyp26c1 |
A |
G |
19: 37,675,009 (GRCm39) |
H110R |
probably damaging |
Het |
| Cyp2j13 |
A |
G |
4: 95,959,932 (GRCm39) |
Y75H |
probably damaging |
Het |
| Defb43 |
T |
A |
14: 63,249,287 (GRCm39) |
V10D |
probably damaging |
Het |
| Dhx36 |
G |
A |
3: 62,401,162 (GRCm39) |
S368L |
possibly damaging |
Het |
| Dock6 |
G |
A |
9: 21,715,923 (GRCm39) |
|
probably benign |
Het |
| Elp2 |
T |
C |
18: 24,745,499 (GRCm39) |
|
probably benign |
Het |
| Emilin3 |
A |
G |
2: 160,750,249 (GRCm39) |
L453P |
probably damaging |
Het |
| Ep300 |
T |
C |
15: 81,500,335 (GRCm39) |
|
probably benign |
Het |
| Ep400 |
G |
A |
5: 110,836,062 (GRCm39) |
T1899M |
unknown |
Het |
| Fancg |
A |
G |
4: 43,002,998 (GRCm39) |
S620P |
probably benign |
Het |
| Fbxo42 |
G |
A |
4: 140,922,550 (GRCm39) |
V239M |
probably damaging |
Het |
| Fermt2 |
T |
C |
14: 45,706,776 (GRCm39) |
D340G |
probably benign |
Het |
| Filip1 |
A |
T |
9: 79,726,672 (GRCm39) |
V649E |
probably damaging |
Het |
| Fut8 |
G |
A |
12: 77,521,791 (GRCm39) |
E477K |
probably damaging |
Het |
| Gbp3 |
G |
A |
3: 142,271,151 (GRCm39) |
G185D |
probably benign |
Het |
| Gclc |
G |
T |
9: 77,694,080 (GRCm39) |
D345Y |
probably damaging |
Het |
| Gfus |
A |
G |
15: 75,800,807 (GRCm39) |
V27A |
possibly damaging |
Het |
| Gkn2 |
A |
G |
6: 87,352,800 (GRCm39) |
D43G |
possibly damaging |
Het |
| Gnptab |
A |
G |
10: 88,279,166 (GRCm39) |
|
probably benign |
Het |
| Greb1l |
C |
T |
18: 10,474,303 (GRCm39) |
T206I |
probably damaging |
Het |
| Grk4 |
A |
G |
5: 34,905,611 (GRCm39) |
N452S |
probably benign |
Het |
| Hcn2 |
G |
C |
10: 79,570,066 (GRCm39) |
|
probably null |
Het |
| Hpn |
T |
C |
7: 30,808,585 (GRCm39) |
K76E |
possibly damaging |
Het |
| Hspg2 |
A |
G |
4: 137,280,591 (GRCm39) |
D3268G |
probably damaging |
Het |
| Immt |
A |
T |
6: 71,848,541 (GRCm39) |
Q467L |
possibly damaging |
Het |
| Kalrn |
T |
C |
16: 33,936,778 (GRCm39) |
S1636G |
probably benign |
Het |
| Kcnh8 |
T |
A |
17: 53,285,141 (GRCm39) |
L1037* |
probably null |
Het |
| Klhl33 |
T |
C |
14: 51,129,851 (GRCm39) |
T548A |
probably damaging |
Het |
| Klri2 |
T |
C |
6: 129,717,171 (GRCm39) |
I71V |
probably benign |
Het |
| Kmt2c |
A |
T |
5: 25,609,363 (GRCm39) |
C254S |
probably damaging |
Het |
| Lama3 |
T |
C |
18: 12,610,647 (GRCm39) |
I1170T |
possibly damaging |
Het |
| Med12l |
A |
G |
3: 59,172,350 (GRCm39) |
Q1702R |
probably damaging |
Het |
| Mga |
A |
T |
2: 119,750,391 (GRCm39) |
|
probably null |
Het |
| Mis18a |
A |
T |
16: 90,517,561 (GRCm39) |
I172K |
possibly damaging |
Het |
| Mrgpre |
T |
C |
7: 143,335,254 (GRCm39) |
D83G |
probably benign |
Het |
| Mroh2a |
C |
A |
1: 88,170,142 (GRCm39) |
A685D |
possibly damaging |
Het |
| Mrpl39 |
T |
C |
16: 84,531,282 (GRCm39) |
|
probably benign |
Het |
| Mrrf |
C |
T |
2: 36,043,710 (GRCm39) |
A149V |
probably benign |
Het |
| Mycbp2 |
A |
T |
14: 103,432,024 (GRCm39) |
M2338K |
possibly damaging |
Het |
| Myo18b |
T |
C |
5: 112,840,632 (GRCm39) |
Q2387R |
probably benign |
Het |
| N4bp2 |
T |
C |
5: 65,964,780 (GRCm39) |
I943T |
probably damaging |
Het |
| Ncapd3 |
T |
A |
9: 26,998,773 (GRCm39) |
N1254K |
probably benign |
Het |
| Ncoa1 |
A |
T |
12: 4,299,758 (GRCm39) |
|
probably null |
Het |
| Ncor2 |
C |
T |
5: 125,126,451 (GRCm39) |
A136T |
probably benign |
Het |
| Opa1 |
T |
C |
16: 29,421,025 (GRCm39) |
|
probably benign |
Het |
| Or13a25 |
A |
G |
7: 140,247,590 (GRCm39) |
D123G |
probably damaging |
Het |
| Or5p59 |
C |
A |
7: 107,703,363 (GRCm39) |
Y282* |
probably null |
Het |
| Or8b39 |
T |
A |
9: 37,996,423 (GRCm39) |
M97K |
possibly damaging |
Het |
| Or9e1 |
T |
A |
11: 58,732,681 (GRCm39) |
I247N |
possibly damaging |
Het |
| Pcdhb4 |
T |
C |
18: 37,440,795 (GRCm39) |
M35T |
probably benign |
Het |
| Per3 |
T |
C |
4: 151,113,288 (GRCm39) |
I347V |
probably benign |
Het |
| Pex13 |
G |
A |
11: 23,615,831 (GRCm39) |
P5L |
possibly damaging |
Het |
| Phkb |
T |
A |
8: 86,602,322 (GRCm39) |
W38R |
probably damaging |
Het |
| Plekhf1 |
A |
T |
7: 37,920,826 (GRCm39) |
D247E |
probably benign |
Het |
| Plxnb2 |
A |
G |
15: 89,042,184 (GRCm39) |
S1607P |
probably benign |
Het |
| Plxnc1 |
T |
A |
10: 94,635,194 (GRCm39) |
H1344L |
possibly damaging |
Het |
| Potefam1 |
A |
C |
2: 111,034,482 (GRCm39) |
V350G |
possibly damaging |
Het |
| Ptk7 |
T |
G |
17: 46,901,238 (GRCm39) |
N196H |
possibly damaging |
Het |
| Rab27a |
G |
T |
9: 72,982,715 (GRCm39) |
D7Y |
probably damaging |
Het |
| Rars2 |
T |
A |
4: 34,630,505 (GRCm39) |
C82* |
probably null |
Het |
| Rccd1 |
A |
T |
7: 79,969,965 (GRCm39) |
|
probably benign |
Het |
| Riiad1 |
T |
C |
3: 94,379,546 (GRCm39) |
I56V |
possibly damaging |
Het |
| Rnase4 |
A |
G |
14: 51,342,507 (GRCm39) |
E77G |
probably damaging |
Het |
| Rnf126 |
A |
T |
10: 79,597,441 (GRCm39) |
I157N |
possibly damaging |
Het |
| Rnf207 |
T |
C |
4: 152,391,925 (GRCm39) |
R623G |
probably benign |
Het |
| Rpusd1 |
T |
G |
17: 25,947,498 (GRCm39) |
F62V |
possibly damaging |
Het |
| Rxfp1 |
T |
C |
3: 79,570,600 (GRCm39) |
|
probably null |
Het |
| Scfd1 |
A |
T |
12: 51,459,411 (GRCm39) |
Q324L |
probably benign |
Het |
| Skint3 |
G |
T |
4: 112,112,974 (GRCm39) |
E195* |
probably null |
Het |
| Slc7a10 |
A |
T |
7: 34,896,758 (GRCm39) |
T165S |
probably benign |
Het |
| Smagp |
A |
G |
15: 100,519,733 (GRCm39) |
I97T |
probably damaging |
Het |
| Sostdc1 |
A |
G |
12: 36,367,340 (GRCm39) |
H172R |
probably damaging |
Het |
| Spast |
A |
G |
17: 74,646,446 (GRCm39) |
|
probably benign |
Het |
| Sspo |
G |
T |
6: 48,467,325 (GRCm39) |
|
probably benign |
Het |
| Ston2 |
C |
T |
12: 91,707,240 (GRCm39) |
|
probably null |
Het |
| Tas2r103 |
T |
G |
6: 133,013,313 (GRCm39) |
E251A |
probably benign |
Het |
| Tbc1d2b |
A |
T |
9: 90,104,558 (GRCm39) |
|
probably benign |
Het |
| Telo2 |
G |
A |
17: 25,332,139 (GRCm39) |
P143L |
probably benign |
Het |
| Tgfbi |
A |
T |
13: 56,786,539 (GRCm39) |
Y674F |
probably null |
Het |
| Tha1 |
T |
A |
11: 117,763,983 (GRCm39) |
|
probably benign |
Het |
| Timp4 |
T |
A |
6: 115,226,814 (GRCm39) |
S110C |
probably damaging |
Het |
| Tlr6 |
T |
C |
5: 65,111,935 (GRCm39) |
K324R |
probably benign |
Het |
| Tnip3 |
A |
G |
6: 65,574,347 (GRCm39) |
E137G |
probably damaging |
Het |
| Top6bl |
A |
G |
19: 4,676,216 (GRCm39) |
S639P |
probably damaging |
Het |
| Trak1 |
T |
C |
9: 121,278,021 (GRCm39) |
|
probably null |
Het |
| Trim47 |
A |
G |
11: 115,999,178 (GRCm39) |
S233P |
probably benign |
Het |
| Tspoap1 |
A |
T |
11: 87,653,635 (GRCm39) |
E155V |
probably damaging |
Het |
| Uggt1 |
A |
T |
1: 36,194,209 (GRCm39) |
L1343Q |
probably damaging |
Het |
| Utp14b |
T |
C |
1: 78,642,452 (GRCm39) |
S117P |
probably benign |
Het |
| Vmn1r124 |
A |
T |
7: 20,994,436 (GRCm39) |
V36D |
probably damaging |
Het |
| Wdr27 |
T |
C |
17: 15,148,658 (GRCm39) |
T112A |
probably benign |
Het |
| Wdr90 |
T |
C |
17: 26,065,367 (GRCm39) |
T1630A |
probably benign |
Het |
| Zfp352 |
A |
G |
4: 90,112,156 (GRCm39) |
T99A |
probably benign |
Het |
|
| Other mutations in Eml6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01071:Eml6
|
APN |
11 |
29,800,816 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01407:Eml6
|
APN |
11 |
29,705,021 (GRCm39) |
nonsense |
probably null |
|
|
IGL01434:Eml6
|
APN |
11 |
29,769,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01578:Eml6
|
APN |
11 |
29,800,870 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01780:Eml6
|
APN |
11 |
29,755,175 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL01821:Eml6
|
APN |
11 |
29,771,699 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01837:Eml6
|
APN |
11 |
29,727,055 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01904:Eml6
|
APN |
11 |
29,788,613 (GRCm39) |
nonsense |
probably null |
|
|
IGL01972:Eml6
|
APN |
11 |
29,788,451 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02134:Eml6
|
APN |
11 |
29,709,066 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02192:Eml6
|
APN |
11 |
29,755,743 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02377:Eml6
|
APN |
11 |
29,727,282 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02584:Eml6
|
APN |
11 |
29,699,387 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02587:Eml6
|
APN |
11 |
29,734,236 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02810:Eml6
|
APN |
11 |
29,799,016 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02873:Eml6
|
APN |
11 |
29,830,700 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL02880:Eml6
|
APN |
11 |
29,699,959 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL03289:Eml6
|
APN |
11 |
29,745,328 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
IGL03301:Eml6
|
APN |
11 |
29,714,083 (GRCm39) |
missense |
probably benign |
0.18 |
|
IGL03386:Eml6
|
APN |
11 |
29,699,934 (GRCm39) |
missense |
probably benign |
|
|
IGL03407:Eml6
|
APN |
11 |
29,856,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4453001:Eml6
|
UTSW |
11 |
29,752,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0125:Eml6
|
UTSW |
11 |
29,832,088 (GRCm39) |
missense |
probably benign |
0.19 |
|
R0240:Eml6
|
UTSW |
11 |
29,742,367 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0240:Eml6
|
UTSW |
11 |
29,742,367 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0271:Eml6
|
UTSW |
11 |
29,798,949 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R0304:Eml6
|
UTSW |
11 |
29,727,441 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0415:Eml6
|
UTSW |
11 |
29,699,392 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0449:Eml6
|
UTSW |
11 |
29,843,213 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0538:Eml6
|
UTSW |
11 |
29,710,010 (GRCm39) |
splice site |
probably benign |
|
|
R0766:Eml6
|
UTSW |
11 |
29,781,219 (GRCm39) |
splice site |
probably benign |
|
|
R0800:Eml6
|
UTSW |
11 |
29,699,877 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0841:Eml6
|
UTSW |
11 |
29,727,430 (GRCm39) |
missense |
probably benign |
0.41 |
|
R0879:Eml6
|
UTSW |
11 |
29,800,816 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1061:Eml6
|
UTSW |
11 |
29,727,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1145:Eml6
|
UTSW |
11 |
29,727,430 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1145:Eml6
|
UTSW |
11 |
29,727,430 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1172:Eml6
|
UTSW |
11 |
29,699,824 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R1173:Eml6
|
UTSW |
11 |
29,699,824 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R1174:Eml6
|
UTSW |
11 |
29,699,824 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R1199:Eml6
|
UTSW |
11 |
29,705,044 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1311:Eml6
|
UTSW |
11 |
29,781,088 (GRCm39) |
splice site |
probably benign |
|
|
R1312:Eml6
|
UTSW |
11 |
29,781,219 (GRCm39) |
splice site |
probably benign |
|
|
R1355:Eml6
|
UTSW |
11 |
29,783,085 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1370:Eml6
|
UTSW |
11 |
29,783,085 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1457:Eml6
|
UTSW |
11 |
29,974,459 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1486:Eml6
|
UTSW |
11 |
29,755,114 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1511:Eml6
|
UTSW |
11 |
29,768,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1532:Eml6
|
UTSW |
11 |
29,742,256 (GRCm39) |
splice site |
probably null |
|
|
R1642:Eml6
|
UTSW |
11 |
29,727,001 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1682:Eml6
|
UTSW |
11 |
29,709,065 (GRCm39) |
missense |
probably benign |
0.13 |
|
R1687:Eml6
|
UTSW |
11 |
29,783,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1699:Eml6
|
UTSW |
11 |
29,696,282 (GRCm39) |
nonsense |
probably null |
|
|
R1796:Eml6
|
UTSW |
11 |
29,831,975 (GRCm39) |
missense |
probably benign |
0.19 |
|
R1797:Eml6
|
UTSW |
11 |
29,832,041 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1837:Eml6
|
UTSW |
11 |
29,699,802 (GRCm39) |
splice site |
probably null |
|
|
R1874:Eml6
|
UTSW |
11 |
29,781,136 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1967:Eml6
|
UTSW |
11 |
29,974,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1969:Eml6
|
UTSW |
11 |
29,783,075 (GRCm39) |
missense |
probably benign |
|
|
R2007:Eml6
|
UTSW |
11 |
29,798,814 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2012:Eml6
|
UTSW |
11 |
29,781,128 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R2198:Eml6
|
UTSW |
11 |
29,800,935 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2217:Eml6
|
UTSW |
11 |
29,768,907 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2218:Eml6
|
UTSW |
11 |
29,768,907 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2403:Eml6
|
UTSW |
11 |
29,752,434 (GRCm39) |
missense |
probably benign |
0.05 |
|
R2520:Eml6
|
UTSW |
11 |
29,741,993 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2937:Eml6
|
UTSW |
11 |
29,783,049 (GRCm39) |
splice site |
probably benign |
|
|
R2938:Eml6
|
UTSW |
11 |
29,783,049 (GRCm39) |
splice site |
probably benign |
|
|
R3085:Eml6
|
UTSW |
11 |
29,759,332 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3236:Eml6
|
UTSW |
11 |
29,781,097 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3738:Eml6
|
UTSW |
11 |
29,753,137 (GRCm39) |
missense |
probably benign |
0.20 |
|
R3739:Eml6
|
UTSW |
11 |
29,753,137 (GRCm39) |
missense |
probably benign |
0.20 |
|
R3752:Eml6
|
UTSW |
11 |
29,759,360 (GRCm39) |
missense |
probably benign |
0.06 |
|
R3854:Eml6
|
UTSW |
11 |
29,699,905 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R3941:Eml6
|
UTSW |
11 |
29,753,167 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4034:Eml6
|
UTSW |
11 |
29,753,137 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4049:Eml6
|
UTSW |
11 |
29,788,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4108:Eml6
|
UTSW |
11 |
29,755,136 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4657:Eml6
|
UTSW |
11 |
29,755,108 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R4662:Eml6
|
UTSW |
11 |
29,727,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4665:Eml6
|
UTSW |
11 |
29,769,007 (GRCm39) |
nonsense |
probably null |
|
|
R4721:Eml6
|
UTSW |
11 |
29,788,525 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4729:Eml6
|
UTSW |
11 |
29,783,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4766:Eml6
|
UTSW |
11 |
29,755,757 (GRCm39) |
missense |
probably benign |
0.22 |
|
R4810:Eml6
|
UTSW |
11 |
29,705,011 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4831:Eml6
|
UTSW |
11 |
29,727,052 (GRCm39) |
nonsense |
probably null |
|
|
R5035:Eml6
|
UTSW |
11 |
29,804,187 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5064:Eml6
|
UTSW |
11 |
29,699,300 (GRCm39) |
missense |
probably benign |
0.12 |
|
R5103:Eml6
|
UTSW |
11 |
29,800,905 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5121:Eml6
|
UTSW |
11 |
29,694,606 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5161:Eml6
|
UTSW |
11 |
29,974,467 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5211:Eml6
|
UTSW |
11 |
29,804,145 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5268:Eml6
|
UTSW |
11 |
29,753,108 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5390:Eml6
|
UTSW |
11 |
29,710,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5529:Eml6
|
UTSW |
11 |
29,714,126 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6239:Eml6
|
UTSW |
11 |
29,699,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6326:Eml6
|
UTSW |
11 |
29,769,066 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6395:Eml6
|
UTSW |
11 |
29,759,321 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6476:Eml6
|
UTSW |
11 |
29,741,971 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6483:Eml6
|
UTSW |
11 |
29,699,875 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6701:Eml6
|
UTSW |
11 |
29,735,748 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6753:Eml6
|
UTSW |
11 |
29,704,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6809:Eml6
|
UTSW |
11 |
29,753,161 (GRCm39) |
missense |
probably benign |
0.23 |
|
R6847:Eml6
|
UTSW |
11 |
29,768,447 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6855:Eml6
|
UTSW |
11 |
29,701,381 (GRCm39) |
splice site |
probably null |
|
|
R7168:Eml6
|
UTSW |
11 |
29,788,529 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7175:Eml6
|
UTSW |
11 |
29,734,231 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7305:Eml6
|
UTSW |
11 |
29,727,258 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7615:Eml6
|
UTSW |
11 |
29,752,501 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R7692:Eml6
|
UTSW |
11 |
29,703,085 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7980:Eml6
|
UTSW |
11 |
29,783,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8026:Eml6
|
UTSW |
11 |
29,699,973 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R8046:Eml6
|
UTSW |
11 |
29,708,981 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8049:Eml6
|
UTSW |
11 |
29,843,201 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8114:Eml6
|
UTSW |
11 |
29,704,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8425:Eml6
|
UTSW |
11 |
29,705,008 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8799:Eml6
|
UTSW |
11 |
29,708,981 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8945:Eml6
|
UTSW |
11 |
29,703,110 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8977:Eml6
|
UTSW |
11 |
29,734,182 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R8986:Eml6
|
UTSW |
11 |
29,755,181 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9088:Eml6
|
UTSW |
11 |
29,768,424 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9150:Eml6
|
UTSW |
11 |
29,755,791 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9209:Eml6
|
UTSW |
11 |
29,781,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9288:Eml6
|
UTSW |
11 |
29,788,641 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9467:Eml6
|
UTSW |
11 |
29,769,076 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9481:Eml6
|
UTSW |
11 |
29,788,641 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9534:Eml6
|
UTSW |
11 |
29,734,155 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
RF037:Eml6
|
UTSW |
11 |
29,702,549 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
RF039:Eml6
|
UTSW |
11 |
29,702,551 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGTGCTGTGTCACTGGAAAGGAAG -3'
(R):5'- ATACTGACAGAGTGGCTGAGCACC -3'
Sequencing Primer
(F):5'- ATTGAAATGCACCTGTGGTCTC -3'
(R):5'- TGAGCACCCTCATGATGC -3'
|
| Posted On |
2013-07-30 |
Incidental Mutation