Incidental Mutation 'R9149:Adamts16'
| ID |
694922 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adamts16
|
| Ensembl Gene |
ENSMUSG00000049538 |
| Gene Name |
ADAM metallopeptidase with thrombospondin type 1 motif 16 |
| Synonyms |
|
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9149 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
70875921-70989930 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 70883948 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Arginine
at position 1076
(C1076R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000079041
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000080145]
[ENSMUST00000123552]
|
| AlphaFold |
Q69Z28 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000080145
AA Change: C1076R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000079041
Gene: ENSMUSG00000049538
AA Change: C1076R
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
26 |
36 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
57 |
203 |
7.8e-34 |
PFAM |
|
Pfam:Reprolysin_5
|
287 |
470 |
2.9e-13 |
PFAM |
|
Pfam:Reprolysin_4
|
289 |
489 |
1.2e-8 |
PFAM |
|
Pfam:Reprolysin
|
289 |
493 |
5.4e-32 |
PFAM |
|
Pfam:Reprolysin_2
|
306 |
483 |
3.7e-10 |
PFAM |
|
Pfam:Reprolysin_3
|
310 |
442 |
6.4e-11 |
PFAM |
|
TSP1
|
587 |
639 |
1.43e-14 |
SMART |
|
Pfam:ADAM_spacer1
|
744 |
856 |
1.3e-37 |
PFAM |
|
TSP1
|
872 |
926 |
3.48e0 |
SMART |
|
TSP1
|
928 |
985 |
4.84e-3 |
SMART |
|
TSP1
|
987 |
1046 |
1.49e-3 |
SMART |
|
TSP1
|
1052 |
1113 |
3.19e-2 |
SMART |
|
TSP1
|
1127 |
1179 |
7.68e-6 |
SMART |
|
Pfam:PLAC
|
1188 |
1218 |
2.9e-13 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000123552
|
| SMART Domains |
Protein: ENSMUSP00000122031
Gene: ENSMUSG00000049538
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
26 |
36 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
56 |
203 |
5.9e-33 |
PFAM |
|
Pfam:Reprolysin_5
|
287 |
470 |
5.1e-14 |
PFAM |
|
Pfam:Reprolysin_4
|
289 |
489 |
2.2e-9 |
PFAM |
|
Pfam:Reprolysin
|
289 |
493 |
1.2e-33 |
PFAM |
|
Pfam:Reprolysin_2
|
306 |
483 |
1.2e-10 |
PFAM |
|
Pfam:Reprolysin_3
|
310 |
442 |
9.7e-11 |
PFAM |
|
TSP1
|
587 |
639 |
1.43e-14 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
100% (90/90) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. This gene is co-expressed with the Wilms tumor protein, Wt1, in the developing glomeruli of embryonic kidneys. The encoded preproprotein undergoes proteolytic processing to generate an active enzyme. [provided by RefSeq, Jul 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930505A04Rik |
C |
T |
11: 30,396,304 (GRCm39) |
S103N |
probably benign |
Het |
| Ace |
A |
G |
11: 105,863,299 (GRCm39) |
D358G |
possibly damaging |
Het |
| Acvr2b |
A |
T |
9: 119,257,116 (GRCm39) |
H115L |
probably damaging |
Het |
| Adam15 |
G |
A |
3: 89,254,742 (GRCm39) |
T106I |
possibly damaging |
Het |
| Adcy5 |
A |
G |
16: 35,092,481 (GRCm39) |
Y614C |
probably damaging |
Het |
| Adhfe1 |
A |
T |
1: 9,627,276 (GRCm39) |
H225L |
probably benign |
Het |
| Aff3 |
A |
G |
1: 38,220,397 (GRCm39) |
I1171T |
probably damaging |
Het |
| Agps |
T |
A |
2: 75,697,182 (GRCm39) |
M334K |
probably damaging |
Het |
| Akr1e1 |
A |
G |
13: 4,652,678 (GRCm39) |
|
probably null |
Het |
| Als2cl |
G |
A |
9: 110,718,191 (GRCm39) |
V311M |
probably benign |
Het |
| Amdhd1 |
A |
T |
10: 93,375,813 (GRCm39) |
L7H |
probably damaging |
Het |
| Apba1 |
A |
T |
19: 23,870,782 (GRCm39) |
I205F |
probably damaging |
Het |
| Arhgap26 |
A |
T |
18: 39,244,917 (GRCm39) |
E187D |
possibly damaging |
Het |
| Ash1l |
A |
T |
3: 88,914,530 (GRCm39) |
H1720L |
probably benign |
Het |
| Atp9a |
T |
C |
2: 168,575,988 (GRCm39) |
|
probably benign |
Het |
| Bcl7c |
G |
A |
7: 127,307,695 (GRCm39) |
A2V |
probably damaging |
Het |
| Catsperg1 |
G |
C |
7: 28,909,912 (GRCm39) |
P72R |
probably benign |
Het |
| Ccdc103 |
G |
A |
11: 102,774,922 (GRCm39) |
G174R |
probably benign |
Het |
| Ccdc171 |
A |
T |
4: 83,612,512 (GRCm39) |
K976M |
probably damaging |
Het |
| Ceacam1 |
T |
C |
7: 25,173,360 (GRCm39) |
N276S |
possibly damaging |
Het |
| Cep152 |
T |
C |
2: 125,461,803 (GRCm39) |
N91S |
probably damaging |
Het |
| Cep152 |
T |
C |
2: 125,463,127 (GRCm39) |
E18G |
probably damaging |
Het |
| Cers3 |
T |
C |
7: 66,393,442 (GRCm39) |
L17P |
probably benign |
Het |
| Cpsf3 |
A |
G |
12: 21,356,844 (GRCm39) |
N489S |
possibly damaging |
Het |
| Cramp1 |
A |
G |
17: 25,187,920 (GRCm39) |
S1225P |
probably damaging |
Het |
| Dck |
G |
A |
5: 88,913,166 (GRCm39) |
G18R |
probably benign |
Het |
| Dnah5 |
A |
T |
15: 28,387,914 (GRCm39) |
E3124D |
probably benign |
Het |
| Dync2i2 |
T |
A |
2: 29,923,953 (GRCm39) |
T191S |
probably benign |
Het |
| Eogt |
T |
G |
6: 97,090,839 (GRCm39) |
L433F |
probably damaging |
Het |
| Fam135b |
A |
G |
15: 71,334,744 (GRCm39) |
S817P |
|
Het |
| Fsip2 |
T |
C |
2: 82,812,374 (GRCm39) |
Y2898H |
possibly damaging |
Het |
| Fzr1 |
T |
C |
10: 81,205,249 (GRCm39) |
H249R |
probably benign |
Het |
| Gbp10 |
T |
G |
5: 105,366,861 (GRCm39) |
Q457P |
probably damaging |
Het |
| Gin1 |
G |
C |
1: 97,710,819 (GRCm39) |
L167F |
probably damaging |
Het |
| Gm14226 |
A |
T |
2: 154,866,843 (GRCm39) |
I267F |
probably damaging |
Het |
| Gmnc |
A |
G |
16: 26,781,642 (GRCm39) |
|
probably null |
Het |
| Hectd2 |
A |
T |
19: 36,576,402 (GRCm39) |
I311F |
probably damaging |
Het |
| Heg1 |
A |
G |
16: 33,558,961 (GRCm39) |
K1085E |
probably benign |
Het |
| Hmbs |
G |
A |
9: 44,252,983 (GRCm39) |
Q34* |
probably null |
Het |
| Hyal6 |
T |
A |
6: 24,734,151 (GRCm39) |
M28K |
probably benign |
Het |
| Ifi27l2a |
T |
C |
12: 103,405,678 (GRCm39) |
V141A |
possibly damaging |
Het |
| Ift122 |
T |
A |
6: 115,867,492 (GRCm39) |
I414N |
probably damaging |
Het |
| Iglv2 |
A |
T |
16: 19,079,434 (GRCm39) |
V23E |
probably damaging |
Het |
| Itgax |
A |
T |
7: 127,730,641 (GRCm39) |
I120L |
probably benign |
Het |
| Kifc3 |
A |
G |
8: 95,853,317 (GRCm39) |
I13T |
probably benign |
Het |
| Lmod3 |
T |
C |
6: 97,224,625 (GRCm39) |
N399D |
probably damaging |
Het |
| Macf1 |
A |
T |
4: 123,365,326 (GRCm39) |
I3145K |
probably benign |
Het |
| Map2k5 |
A |
C |
9: 63,201,006 (GRCm39) |
I209S |
probably damaging |
Het |
| Mbd5 |
A |
G |
2: 49,141,388 (GRCm39) |
E117G |
probably damaging |
Het |
| Milr1 |
A |
G |
11: 106,652,105 (GRCm39) |
H172R |
probably benign |
Het |
| Myod1 |
A |
C |
7: 46,026,593 (GRCm39) |
D166A |
|
Het |
| Neb |
C |
T |
2: 52,100,878 (GRCm39) |
V4647M |
possibly damaging |
Het |
| Nek1 |
A |
T |
8: 61,574,055 (GRCm39) |
D1101V |
probably damaging |
Het |
| Nlrp2 |
A |
T |
7: 5,330,572 (GRCm39) |
V608D |
probably benign |
Het |
| Noc3l |
G |
A |
19: 38,800,835 (GRCm39) |
Q216* |
probably null |
Het |
| Nos1 |
G |
C |
5: 118,017,402 (GRCm39) |
R255P |
probably benign |
Het |
| Nup160 |
T |
A |
2: 90,552,585 (GRCm39) |
|
probably benign |
Het |
| Nxt2 |
C |
T |
X: 141,020,747 (GRCm39) |
A118V |
possibly damaging |
Het |
| Oat |
C |
T |
7: 132,166,006 (GRCm39) |
S193N |
probably benign |
Het |
| Oma1 |
A |
G |
4: 103,182,214 (GRCm39) |
|
probably null |
Het |
| Or12e13 |
G |
T |
2: 87,663,523 (GRCm39) |
G47* |
probably null |
Het |
| Or1e16 |
T |
A |
11: 73,286,853 (GRCm39) |
|
probably benign |
Het |
| Or1j15 |
T |
G |
2: 36,458,988 (GRCm39) |
F126C |
probably benign |
Het |
| Or6c206 |
A |
G |
10: 129,097,184 (GRCm39) |
Y118C |
probably damaging |
Het |
| Or6c216 |
A |
G |
10: 129,678,482 (GRCm39) |
V143A |
probably damaging |
Het |
| Os9 |
A |
G |
10: 126,933,918 (GRCm39) |
S500P |
possibly damaging |
Het |
| Osbpl11 |
A |
T |
16: 33,047,660 (GRCm39) |
N541I |
|
Het |
| Pcnx4 |
A |
G |
12: 72,613,671 (GRCm39) |
I539V |
probably benign |
Het |
| Ppfia3 |
T |
A |
7: 44,999,717 (GRCm39) |
|
probably null |
Het |
| Ppp1r3a |
T |
C |
6: 14,722,098 (GRCm39) |
K275E |
probably benign |
Het |
| Pten |
A |
G |
19: 32,769,972 (GRCm39) |
N63S |
probably benign |
Het |
| Rptor |
A |
G |
11: 119,777,896 (GRCm39) |
N1020S |
probably benign |
Het |
| Sall2 |
C |
A |
14: 52,550,673 (GRCm39) |
D841Y |
possibly damaging |
Het |
| Sbno1 |
T |
A |
5: 124,519,762 (GRCm39) |
H1172L |
probably benign |
Het |
| Scaf4 |
A |
T |
16: 90,027,054 (GRCm39) |
L921Q |
probably damaging |
Het |
| Sec22c |
C |
A |
9: 121,524,750 (GRCm39) |
R11L |
probably damaging |
Het |
| Skint6 |
T |
A |
4: 113,034,173 (GRCm39) |
D318V |
probably damaging |
Het |
| Slc22a28 |
T |
C |
19: 8,049,205 (GRCm39) |
N348S |
probably benign |
Het |
| Slc44a2 |
G |
T |
9: 21,253,305 (GRCm39) |
K77N |
possibly damaging |
Het |
| Smc1b |
C |
T |
15: 84,950,431 (GRCm39) |
V1198I |
probably benign |
Het |
| Spef2 |
A |
T |
15: 9,717,568 (GRCm39) |
M316K |
probably damaging |
Het |
| Stra8 |
T |
C |
6: 34,911,016 (GRCm39) |
Y215H |
probably damaging |
Het |
| Sv2a |
G |
T |
3: 96,097,010 (GRCm39) |
R445L |
probably benign |
Het |
| Sycp1 |
A |
C |
3: 102,758,944 (GRCm39) |
L771R |
probably damaging |
Het |
| Tchp |
A |
T |
5: 114,859,184 (GRCm39) |
R493* |
probably null |
Het |
| Ttc13 |
G |
A |
8: 125,410,039 (GRCm39) |
A391V |
probably benign |
Het |
| Unc13b |
C |
T |
4: 43,176,186 (GRCm39) |
T2338I |
unknown |
Het |
| Wac |
A |
G |
18: 7,921,592 (GRCm39) |
D576G |
probably damaging |
Het |
| Xdh |
T |
C |
17: 74,222,688 (GRCm39) |
N559S |
probably benign |
Het |
| Zscan20 |
A |
T |
4: 128,481,914 (GRCm39) |
S583T |
probably benign |
Het |
|
| Other mutations in Adamts16 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01024:Adamts16
|
APN |
13 |
70,943,603 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01338:Adamts16
|
APN |
13 |
70,984,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01663:Adamts16
|
APN |
13 |
70,941,260 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01804:Adamts16
|
APN |
13 |
70,949,080 (GRCm39) |
nonsense |
probably null |
|
|
IGL01874:Adamts16
|
APN |
13 |
70,916,823 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL01984:Adamts16
|
APN |
13 |
70,935,266 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02305:Adamts16
|
APN |
13 |
70,921,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02350:Adamts16
|
APN |
13 |
70,886,704 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02357:Adamts16
|
APN |
13 |
70,886,704 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02429:Adamts16
|
APN |
13 |
70,935,289 (GRCm39) |
splice site |
probably benign |
|
|
IGL02450:Adamts16
|
APN |
13 |
70,984,419 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02807:Adamts16
|
APN |
13 |
70,886,897 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03356:Adamts16
|
APN |
13 |
70,901,410 (GRCm39) |
missense |
probably benign |
0.00 |
|
swap
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
switcheroo
|
UTSW |
13 |
70,949,073 (GRCm39) |
missense |
probably benign |
|
|
R0046:Adamts16
|
UTSW |
13 |
70,911,579 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0046:Adamts16
|
UTSW |
13 |
70,911,579 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0201:Adamts16
|
UTSW |
13 |
70,927,763 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0326:Adamts16
|
UTSW |
13 |
70,927,730 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0336:Adamts16
|
UTSW |
13 |
70,939,913 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R0369:Adamts16
|
UTSW |
13 |
70,927,671 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0422:Adamts16
|
UTSW |
13 |
70,887,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0507:Adamts16
|
UTSW |
13 |
70,916,766 (GRCm39) |
missense |
probably benign |
|
|
R0524:Adamts16
|
UTSW |
13 |
70,949,013 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0590:Adamts16
|
UTSW |
13 |
70,949,073 (GRCm39) |
missense |
probably benign |
|
|
R0734:Adamts16
|
UTSW |
13 |
70,886,600 (GRCm39) |
splice site |
probably benign |
|
|
R0787:Adamts16
|
UTSW |
13 |
70,886,948 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0826:Adamts16
|
UTSW |
13 |
70,916,811 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R0920:Adamts16
|
UTSW |
13 |
70,911,680 (GRCm39) |
splice site |
probably benign |
|
|
R1027:Adamts16
|
UTSW |
13 |
70,915,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1462:Adamts16
|
UTSW |
13 |
70,984,253 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1462:Adamts16
|
UTSW |
13 |
70,984,253 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1535:Adamts16
|
UTSW |
13 |
70,939,913 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1617:Adamts16
|
UTSW |
13 |
70,946,154 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1700:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1734:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1736:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1737:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1738:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1746:Adamts16
|
UTSW |
13 |
70,927,717 (GRCm39) |
splice site |
probably null |
|
|
R1869:Adamts16
|
UTSW |
13 |
70,883,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1944:Adamts16
|
UTSW |
13 |
70,940,005 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1997:Adamts16
|
UTSW |
13 |
70,901,386 (GRCm39) |
missense |
probably benign |
0.39 |
|
R2018:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R2135:Adamts16
|
UTSW |
13 |
70,949,126 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2219:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R2228:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R3410:Adamts16
|
UTSW |
13 |
70,901,345 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3411:Adamts16
|
UTSW |
13 |
70,901,345 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3842:Adamts16
|
UTSW |
13 |
70,887,010 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4117:Adamts16
|
UTSW |
13 |
70,916,111 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4435:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4436:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4526:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4552:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4555:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4556:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4557:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4579:Adamts16
|
UTSW |
13 |
70,927,743 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4639:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4640:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4641:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4642:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4672:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R5350:Adamts16
|
UTSW |
13 |
70,901,315 (GRCm39) |
nonsense |
probably null |
|
|
R5464:Adamts16
|
UTSW |
13 |
70,909,868 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5613:Adamts16
|
UTSW |
13 |
70,878,253 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5667:Adamts16
|
UTSW |
13 |
70,984,494 (GRCm39) |
nonsense |
probably null |
|
|
R5735:Adamts16
|
UTSW |
13 |
70,984,337 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5762:Adamts16
|
UTSW |
13 |
70,886,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5907:Adamts16
|
UTSW |
13 |
70,877,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6169:Adamts16
|
UTSW |
13 |
70,918,393 (GRCm39) |
nonsense |
probably null |
|
|
R6351:Adamts16
|
UTSW |
13 |
70,984,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6665:Adamts16
|
UTSW |
13 |
70,927,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6913:Adamts16
|
UTSW |
13 |
70,877,017 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6982:Adamts16
|
UTSW |
13 |
70,916,639 (GRCm39) |
splice site |
probably null |
|
|
R6996:Adamts16
|
UTSW |
13 |
70,946,157 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7313:Adamts16
|
UTSW |
13 |
70,921,074 (GRCm39) |
nonsense |
probably null |
|
|
R7356:Adamts16
|
UTSW |
13 |
70,984,399 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7509:Adamts16
|
UTSW |
13 |
70,935,283 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7595:Adamts16
|
UTSW |
13 |
70,878,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7782:Adamts16
|
UTSW |
13 |
70,984,265 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7968:Adamts16
|
UTSW |
13 |
70,886,701 (GRCm39) |
missense |
probably benign |
|
|
R8231:Adamts16
|
UTSW |
13 |
70,925,599 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8232:Adamts16
|
UTSW |
13 |
70,941,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8470:Adamts16
|
UTSW |
13 |
70,984,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8485:Adamts16
|
UTSW |
13 |
70,886,794 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8772:Adamts16
|
UTSW |
13 |
70,984,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8916:Adamts16
|
UTSW |
13 |
70,941,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8921:Adamts16
|
UTSW |
13 |
70,939,910 (GRCm39) |
splice site |
probably benign |
|
|
R8973:Adamts16
|
UTSW |
13 |
70,886,959 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9132:Adamts16
|
UTSW |
13 |
70,901,408 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9159:Adamts16
|
UTSW |
13 |
70,901,408 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9312:Adamts16
|
UTSW |
13 |
70,949,045 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9584:Adamts16
|
UTSW |
13 |
70,949,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Adamts16
|
UTSW |
13 |
70,909,892 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGTTTCAGCAGCATGTGGAG -3'
(R):5'- TTTAAAATGCCAAGGCCCAAGC -3'
Sequencing Primer
(F):5'- GTGTGAGCCAGCCATCAAC -3'
(R):5'- GCCCAAGCCATGAAACATC -3'
|
| Posted On |
2022-01-20 |
Incidental Mutation