Incidental Mutation 'R1793:Ubr3'
| ID |
201895 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ubr3
|
| Ensembl Gene |
ENSMUSG00000044308 |
| Gene Name |
ubiquitin protein ligase E3 component n-recognin 3 |
| Synonyms |
1110059H15Rik, 4833421P10Rik, A130030D10Rik, Zfp650 |
| MMRRC Submission |
039823-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1793 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
69727590-69854357 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
C to T
at 69830895 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000122027
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000055758]
[ENSMUST00000112251]
[ENSMUST00000152610]
|
| AlphaFold |
Q5U430 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000055758
|
| SMART Domains |
Protein: ENSMUSP00000060159
Gene: ENSMUSG00000044308
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
13 |
40 |
N/A |
INTRINSIC |
|
low complexity region
|
67 |
88 |
N/A |
INTRINSIC |
|
Pfam:zf-UBR
|
118 |
188 |
1.6e-19 |
PFAM |
|
low complexity region
|
339 |
354 |
N/A |
INTRINSIC |
|
low complexity region
|
570 |
580 |
N/A |
INTRINSIC |
|
low complexity region
|
1016 |
1027 |
N/A |
INTRINSIC |
|
low complexity region
|
1082 |
1101 |
N/A |
INTRINSIC |
|
coiled coil region
|
1167 |
1199 |
N/A |
INTRINSIC |
|
Blast:RING
|
1289 |
1363 |
8e-39 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112251
|
| SMART Domains |
Protein: ENSMUSP00000107870
Gene: ENSMUSG00000044308
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
13 |
40 |
N/A |
INTRINSIC |
|
low complexity region
|
67 |
88 |
N/A |
INTRINSIC |
|
Pfam:zf-UBR
|
119 |
187 |
1.7e-21 |
PFAM |
|
low complexity region
|
338 |
353 |
N/A |
INTRINSIC |
|
low complexity region
|
569 |
579 |
N/A |
INTRINSIC |
|
low complexity region
|
1015 |
1026 |
N/A |
INTRINSIC |
|
low complexity region
|
1081 |
1100 |
N/A |
INTRINSIC |
|
coiled coil region
|
1166 |
1198 |
N/A |
INTRINSIC |
|
Blast:RING
|
1288 |
1362 |
8e-39 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000125608
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000126165
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152610
|
| SMART Domains |
Protein: ENSMUSP00000122027
Gene: ENSMUSG00000044308
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:RING
|
1 |
57 |
1e-34 |
BLAST |
|
SCOP:d1jm7a_
|
20 |
84 |
4e-3 |
SMART |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.4%
- 20x: 92.9%
|
| Validation Efficiency |
100% (122/122) |
| MGI Phenotype |
PHENOTYPE: Homozygous null mice obtained on a coisogenic 129S1 background die early in embryogenesis while those on a mixed 129S1/B6 background are born at a slightly reduced frequency. On a congenic C57BL/6 background, homozygotes display neonatal lethality, impaired suckling and female behavioral anosmia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 118 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930522L14Rik |
A |
T |
5: 109,884,144 (GRCm39) |
H571Q |
probably damaging |
Het |
| Abcf2 |
T |
A |
5: 24,773,774 (GRCm39) |
M372L |
probably benign |
Het |
| Acaca |
A |
C |
11: 84,206,795 (GRCm39) |
T1552P |
probably damaging |
Het |
| Acaca |
A |
G |
11: 84,229,219 (GRCm39) |
D1682G |
probably damaging |
Het |
| Acvr1b |
T |
C |
15: 101,091,906 (GRCm39) |
V62A |
probably benign |
Het |
| Aimp1 |
C |
T |
3: 132,379,825 (GRCm39) |
V97M |
probably benign |
Het |
| Aldh1l1 |
C |
T |
6: 90,554,813 (GRCm39) |
T557I |
possibly damaging |
Het |
| Alpk1 |
T |
C |
3: 127,471,447 (GRCm39) |
T1012A |
probably damaging |
Het |
| Amot |
G |
A |
X: 144,233,585 (GRCm39) |
|
probably benign |
Het |
| Arap1 |
T |
A |
7: 101,037,829 (GRCm39) |
H477Q |
probably benign |
Het |
| Arhgap18 |
T |
A |
10: 26,736,732 (GRCm39) |
|
probably benign |
Het |
| Arhgef10l |
C |
T |
4: 140,242,684 (GRCm39) |
V862M |
probably damaging |
Het |
| Arl4d |
A |
G |
11: 101,557,554 (GRCm39) |
I27V |
probably benign |
Het |
| Asb18 |
G |
A |
1: 89,942,277 (GRCm39) |
P8L |
probably damaging |
Het |
| Ash1l |
A |
G |
3: 88,977,616 (GRCm39) |
H2682R |
probably damaging |
Het |
| Aspm |
T |
A |
1: 139,385,079 (GRCm39) |
V241E |
probably benign |
Het |
| Atf7ip |
G |
T |
6: 136,586,217 (GRCm39) |
|
probably benign |
Het |
| AY358078 |
T |
G |
14: 52,042,051 (GRCm39) |
M142R |
unknown |
Het |
| C3 |
T |
A |
17: 57,526,592 (GRCm39) |
K796N |
possibly damaging |
Het |
| Ceacam16 |
T |
C |
7: 19,590,041 (GRCm39) |
T301A |
probably damaging |
Het |
| Ceacam5 |
T |
G |
7: 17,481,320 (GRCm39) |
Y356D |
probably benign |
Het |
| Cep192 |
C |
T |
18: 67,984,838 (GRCm39) |
A1616V |
possibly damaging |
Het |
| Cfap91 |
T |
A |
16: 38,141,781 (GRCm39) |
N384Y |
possibly damaging |
Het |
| Cherp |
A |
T |
8: 73,216,994 (GRCm39) |
H645Q |
probably benign |
Het |
| CK137956 |
T |
C |
4: 127,845,242 (GRCm39) |
D167G |
probably benign |
Het |
| Clcn1 |
T |
A |
6: 42,275,860 (GRCm39) |
|
probably null |
Het |
| Cntn1 |
C |
T |
15: 92,189,552 (GRCm39) |
T625I |
possibly damaging |
Het |
| Cpn2 |
T |
A |
16: 30,078,142 (GRCm39) |
N520Y |
probably damaging |
Het |
| Crocc |
G |
A |
4: 140,746,620 (GRCm39) |
R1762W |
probably damaging |
Het |
| Cts3 |
C |
A |
13: 61,715,967 (GRCm39) |
V100F |
probably benign |
Het |
| Ddx56 |
A |
T |
11: 6,216,934 (GRCm39) |
V87D |
probably damaging |
Het |
| Dnah9 |
C |
T |
11: 66,010,420 (GRCm39) |
|
probably null |
Het |
| Dock1 |
T |
A |
7: 134,700,456 (GRCm39) |
|
probably null |
Het |
| Dst |
T |
A |
1: 34,191,552 (GRCm39) |
Y291* |
probably null |
Het |
| Eif4g3 |
T |
C |
4: 137,898,442 (GRCm39) |
I1071T |
probably damaging |
Het |
| Fblim1 |
T |
C |
4: 141,322,549 (GRCm39) |
Q78R |
probably damaging |
Het |
| Fcamr |
C |
T |
1: 130,739,284 (GRCm39) |
P195S |
probably benign |
Het |
| Fcho1 |
G |
A |
8: 72,161,666 (GRCm39) |
Q835* |
probably null |
Het |
| Frem3 |
A |
G |
8: 81,339,741 (GRCm39) |
N678S |
probably benign |
Het |
| Frk |
G |
A |
10: 34,483,878 (GRCm39) |
R413H |
probably benign |
Het |
| Gm10619 |
C |
A |
7: 73,459,758 (GRCm39) |
|
noncoding transcript |
Het |
| Gm12185 |
G |
A |
11: 48,806,583 (GRCm39) |
R203* |
probably null |
Het |
| Gm12886 |
A |
G |
4: 121,280,174 (GRCm39) |
V34A |
probably benign |
Het |
| Gna12 |
A |
T |
5: 140,746,707 (GRCm39) |
I246N |
probably damaging |
Het |
| Gpm6a |
T |
C |
8: 55,507,867 (GRCm39) |
M201T |
probably benign |
Het |
| Gpsm2 |
T |
G |
3: 108,608,225 (GRCm39) |
D220A |
probably benign |
Het |
| Grip2 |
C |
G |
6: 91,760,623 (GRCm39) |
V325L |
probably benign |
Het |
| Grk5 |
C |
A |
19: 61,065,200 (GRCm39) |
A288D |
probably damaging |
Het |
| Herpud2 |
G |
A |
9: 25,021,953 (GRCm39) |
A231V |
possibly damaging |
Het |
| Hmcn1 |
T |
C |
1: 150,624,834 (GRCm39) |
S1024G |
probably benign |
Het |
| Hp1bp3 |
A |
G |
4: 137,957,820 (GRCm39) |
D295G |
probably damaging |
Het |
| Igsf21 |
T |
C |
4: 139,761,703 (GRCm39) |
H325R |
probably damaging |
Het |
| Ing2 |
T |
A |
8: 48,122,364 (GRCm39) |
L61F |
probably damaging |
Het |
| Jak3 |
T |
C |
8: 72,138,590 (GRCm39) |
|
probably benign |
Het |
| Kcnn3 |
T |
A |
3: 89,516,712 (GRCm39) |
C374S |
probably benign |
Het |
| Klk1b22 |
A |
G |
7: 43,765,775 (GRCm39) |
|
probably benign |
Het |
| Larp1 |
T |
C |
11: 57,940,764 (GRCm39) |
M630T |
possibly damaging |
Het |
| Lhx5 |
T |
A |
5: 120,572,725 (GRCm39) |
C115S |
probably damaging |
Het |
| Lmcd1 |
C |
A |
6: 112,305,712 (GRCm39) |
T271K |
probably benign |
Het |
| Lpar1 |
G |
A |
4: 58,486,798 (GRCm39) |
R158* |
probably null |
Het |
| Lyst |
T |
A |
13: 13,821,668 (GRCm39) |
C1347* |
probably null |
Het |
| Map3k8 |
G |
A |
18: 4,332,389 (GRCm39) |
Q441* |
probably null |
Het |
| Mboat1 |
T |
C |
13: 30,403,633 (GRCm39) |
V144A |
probably damaging |
Het |
| Mcur1 |
C |
T |
13: 43,713,491 (GRCm39) |
G38S |
unknown |
Het |
| Med13 |
T |
A |
11: 86,220,177 (GRCm39) |
M276L |
probably benign |
Het |
| Mefv |
A |
G |
16: 3,526,528 (GRCm39) |
S699P |
possibly damaging |
Het |
| Mfsd4a |
C |
A |
1: 131,987,077 (GRCm39) |
A62S |
probably damaging |
Het |
| Mmp27 |
A |
G |
9: 7,571,459 (GRCm39) |
M1V |
probably null |
Het |
| Myo1c |
C |
T |
11: 75,548,415 (GRCm39) |
T58I |
probably damaging |
Het |
| Myom3 |
A |
T |
4: 135,538,066 (GRCm39) |
D1316V |
probably benign |
Het |
| Naa25 |
T |
A |
5: 121,555,478 (GRCm39) |
C235S |
possibly damaging |
Het |
| Naa25 |
C |
A |
5: 121,558,656 (GRCm39) |
R333S |
probably damaging |
Het |
| Nav3 |
G |
A |
10: 109,539,233 (GRCm39) |
T2056I |
probably benign |
Het |
| Nol4 |
A |
G |
18: 22,902,878 (GRCm39) |
Y378H |
probably damaging |
Het |
| Npat |
G |
A |
9: 53,463,589 (GRCm39) |
R124Q |
probably damaging |
Het |
| Npr3 |
T |
A |
15: 11,848,665 (GRCm39) |
E434V |
probably benign |
Het |
| Nptx2 |
A |
G |
5: 144,485,130 (GRCm39) |
T208A |
probably benign |
Het |
| Obscn |
C |
T |
11: 58,968,606 (GRCm39) |
V2798M |
probably damaging |
Het |
| Odad4 |
C |
A |
11: 100,460,679 (GRCm39) |
|
probably null |
Het |
| Or10j7 |
A |
T |
1: 173,011,976 (GRCm39) |
H8Q |
probably benign |
Het |
| Or52r1 |
A |
G |
7: 102,537,250 (GRCm39) |
Y37H |
probably benign |
Het |
| Or5b122 |
C |
T |
19: 13,562,779 (GRCm39) |
T37I |
probably benign |
Het |
| Padi1 |
G |
A |
4: 140,541,967 (GRCm39) |
P652S |
probably damaging |
Het |
| Pcdh1 |
G |
T |
18: 38,331,938 (GRCm39) |
P355Q |
probably damaging |
Het |
| Pck2 |
G |
A |
14: 55,781,422 (GRCm39) |
R189H |
possibly damaging |
Het |
| Pcsk5 |
T |
A |
19: 17,432,114 (GRCm39) |
K1500N |
possibly damaging |
Het |
| Phc3 |
A |
T |
3: 31,002,865 (GRCm39) |
S218T |
probably damaging |
Het |
| Piezo2 |
T |
A |
18: 63,239,355 (GRCm39) |
M510L |
possibly damaging |
Het |
| Polr1g |
T |
C |
7: 19,091,904 (GRCm39) |
T68A |
possibly damaging |
Het |
| Ppp1r3a |
A |
T |
6: 14,754,717 (GRCm39) |
Y177N |
probably damaging |
Het |
| Psme2b |
A |
T |
11: 48,836,361 (GRCm39) |
D195E |
probably damaging |
Het |
| Ptprr |
T |
C |
10: 116,088,827 (GRCm39) |
V463A |
probably damaging |
Het |
| Pwwp2b |
G |
A |
7: 138,836,281 (GRCm39) |
R574Q |
probably damaging |
Het |
| Rap1gds1 |
T |
A |
3: 138,756,314 (GRCm39) |
T14S |
possibly damaging |
Het |
| Rbm11 |
A |
T |
16: 75,397,685 (GRCm39) |
K205M |
probably damaging |
Het |
| Rfx1 |
T |
A |
8: 84,793,050 (GRCm39) |
|
probably benign |
Het |
| Rnasel |
C |
A |
1: 153,630,169 (GRCm39) |
H228Q |
probably damaging |
Het |
| Sap130 |
T |
A |
18: 31,831,640 (GRCm39) |
I710K |
probably benign |
Het |
| Slc27a4 |
C |
A |
2: 29,695,733 (GRCm39) |
D89E |
probably benign |
Het |
| Spata31d1b |
T |
C |
13: 59,863,779 (GRCm39) |
V309A |
probably benign |
Het |
| Syt7 |
T |
G |
19: 10,421,354 (GRCm39) |
Y420D |
probably damaging |
Het |
| Tanc2 |
A |
G |
11: 105,515,859 (GRCm39) |
|
probably null |
Het |
| Tbc1d10b |
A |
G |
7: 126,802,930 (GRCm39) |
S333P |
possibly damaging |
Het |
| Tenm2 |
G |
A |
11: 35,914,209 (GRCm39) |
P2442S |
probably damaging |
Het |
| Tenm3 |
C |
T |
8: 49,127,579 (GRCm39) |
C33Y |
probably damaging |
Het |
| Timmdc1 |
A |
G |
16: 38,319,419 (GRCm39) |
L245P |
possibly damaging |
Het |
| Tlr5 |
T |
C |
1: 182,800,012 (GRCm39) |
F5L |
probably benign |
Het |
| Ttll4 |
T |
A |
1: 74,726,999 (GRCm39) |
F784L |
possibly damaging |
Het |
| Tulp4 |
A |
G |
17: 6,189,387 (GRCm39) |
T70A |
possibly damaging |
Het |
| Txndc17 |
T |
A |
11: 72,099,571 (GRCm39) |
N81K |
probably benign |
Het |
| Uri1 |
A |
C |
7: 37,681,116 (GRCm39) |
V96G |
probably damaging |
Het |
| Uspl1 |
T |
A |
5: 149,150,246 (GRCm39) |
I482N |
probably damaging |
Het |
| Vmn1r229 |
A |
G |
17: 21,034,974 (GRCm39) |
N73S |
possibly damaging |
Het |
| Vwa7 |
G |
T |
17: 35,243,388 (GRCm39) |
G689* |
probably null |
Het |
| Zfp114 |
T |
A |
7: 23,877,164 (GRCm39) |
|
probably null |
Het |
| Zfp618 |
A |
G |
4: 63,051,474 (GRCm39) |
S659G |
probably damaging |
Het |
| Zfp872 |
A |
G |
9: 22,111,349 (GRCm39) |
K275R |
probably damaging |
Het |
| Zzef1 |
C |
T |
11: 72,777,535 (GRCm39) |
P1789S |
probably damaging |
Het |
|
| Other mutations in Ubr3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00088:Ubr3
|
APN |
2 |
69,819,154 (GRCm39) |
missense |
probably benign |
0.40 |
|
IGL00985:Ubr3
|
APN |
2 |
69,833,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01061:Ubr3
|
APN |
2 |
69,813,569 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01325:Ubr3
|
APN |
2 |
69,747,441 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL01398:Ubr3
|
APN |
2 |
69,789,997 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01484:Ubr3
|
APN |
2 |
69,851,888 (GRCm39) |
nonsense |
probably null |
|
|
IGL01599:Ubr3
|
APN |
2 |
69,768,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01616:Ubr3
|
APN |
2 |
69,850,828 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL01634:Ubr3
|
APN |
2 |
69,803,916 (GRCm39) |
missense |
probably benign |
|
|
IGL01684:Ubr3
|
APN |
2 |
69,846,502 (GRCm39) |
nonsense |
probably null |
|
|
IGL01810:Ubr3
|
APN |
2 |
69,833,809 (GRCm39) |
splice site |
probably null |
|
|
IGL01813:Ubr3
|
APN |
2 |
69,781,914 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL01994:Ubr3
|
APN |
2 |
69,851,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02188:Ubr3
|
APN |
2 |
69,789,955 (GRCm39) |
nonsense |
probably null |
|
|
IGL02318:Ubr3
|
APN |
2 |
69,809,741 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02379:Ubr3
|
APN |
2 |
69,778,832 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02635:Ubr3
|
APN |
2 |
69,850,827 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02858:Ubr3
|
APN |
2 |
69,783,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03140:Ubr3
|
APN |
2 |
69,800,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03343:Ubr3
|
APN |
2 |
69,803,490 (GRCm39) |
splice site |
probably benign |
|
|
Hyrax
|
UTSW |
2 |
69,783,212 (GRCm39) |
missense |
probably benign |
0.32 |
|
manatee
|
UTSW |
2 |
69,809,730 (GRCm39) |
nonsense |
probably null |
|
|
sea_cow
|
UTSW |
2 |
69,790,013 (GRCm39) |
splice site |
probably null |
|
|
R0094:Ubr3
|
UTSW |
2 |
69,781,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0094:Ubr3
|
UTSW |
2 |
69,781,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0122:Ubr3
|
UTSW |
2 |
69,809,756 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0243:Ubr3
|
UTSW |
2 |
69,781,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0710:Ubr3
|
UTSW |
2 |
69,783,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0787:Ubr3
|
UTSW |
2 |
69,781,765 (GRCm39) |
splice site |
probably benign |
|
|
R1137:Ubr3
|
UTSW |
2 |
69,768,659 (GRCm39) |
splice site |
probably benign |
|
|
R1191:Ubr3
|
UTSW |
2 |
69,851,525 (GRCm39) |
nonsense |
probably null |
|
|
R1416:Ubr3
|
UTSW |
2 |
69,775,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1623:Ubr3
|
UTSW |
2 |
69,808,067 (GRCm39) |
nonsense |
probably null |
|
|
R1735:Ubr3
|
UTSW |
2 |
69,839,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1789:Ubr3
|
UTSW |
2 |
69,846,711 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1932:Ubr3
|
UTSW |
2 |
69,783,820 (GRCm39) |
splice site |
probably null |
|
|
R2042:Ubr3
|
UTSW |
2 |
69,808,118 (GRCm39) |
nonsense |
probably null |
|
|
R2085:Ubr3
|
UTSW |
2 |
69,784,108 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2090:Ubr3
|
UTSW |
2 |
69,766,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2112:Ubr3
|
UTSW |
2 |
69,808,136 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2173:Ubr3
|
UTSW |
2 |
69,727,743 (GRCm39) |
missense |
probably benign |
|
|
R2215:Ubr3
|
UTSW |
2 |
69,809,661 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R2273:Ubr3
|
UTSW |
2 |
69,846,685 (GRCm39) |
missense |
probably benign |
0.11 |
|
R2274:Ubr3
|
UTSW |
2 |
69,846,685 (GRCm39) |
missense |
probably benign |
0.11 |
|
R2275:Ubr3
|
UTSW |
2 |
69,846,685 (GRCm39) |
missense |
probably benign |
0.11 |
|
R2292:Ubr3
|
UTSW |
2 |
69,727,604 (GRCm39) |
unclassified |
probably benign |
|
|
R2447:Ubr3
|
UTSW |
2 |
69,833,724 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2504:Ubr3
|
UTSW |
2 |
69,768,542 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2517:Ubr3
|
UTSW |
2 |
69,766,362 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2901:Ubr3
|
UTSW |
2 |
69,846,536 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3109:Ubr3
|
UTSW |
2 |
69,819,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3737:Ubr3
|
UTSW |
2 |
69,801,578 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3793:Ubr3
|
UTSW |
2 |
69,747,525 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R3821:Ubr3
|
UTSW |
2 |
69,824,157 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3918:Ubr3
|
UTSW |
2 |
69,846,474 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4157:Ubr3
|
UTSW |
2 |
69,790,013 (GRCm39) |
splice site |
probably null |
|
|
R4235:Ubr3
|
UTSW |
2 |
69,846,729 (GRCm39) |
nonsense |
probably null |
|
|
R4276:Ubr3
|
UTSW |
2 |
69,768,731 (GRCm39) |
nonsense |
probably null |
|
|
R4544:Ubr3
|
UTSW |
2 |
69,786,437 (GRCm39) |
missense |
probably benign |
0.18 |
|
R4678:Ubr3
|
UTSW |
2 |
69,766,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4707:Ubr3
|
UTSW |
2 |
69,768,714 (GRCm39) |
intron |
probably benign |
|
|
R4785:Ubr3
|
UTSW |
2 |
69,789,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4872:Ubr3
|
UTSW |
2 |
69,800,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4887:Ubr3
|
UTSW |
2 |
69,843,475 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4920:Ubr3
|
UTSW |
2 |
69,783,212 (GRCm39) |
missense |
probably benign |
0.32 |
|
R4989:Ubr3
|
UTSW |
2 |
69,850,790 (GRCm39) |
splice site |
probably benign |
|
|
R5104:Ubr3
|
UTSW |
2 |
69,768,600 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5134:Ubr3
|
UTSW |
2 |
69,850,790 (GRCm39) |
splice site |
probably benign |
|
|
R5137:Ubr3
|
UTSW |
2 |
69,803,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5174:Ubr3
|
UTSW |
2 |
69,839,506 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5195:Ubr3
|
UTSW |
2 |
69,786,378 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5437:Ubr3
|
UTSW |
2 |
69,774,734 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5539:Ubr3
|
UTSW |
2 |
69,850,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5781:Ubr3
|
UTSW |
2 |
69,846,588 (GRCm39) |
splice site |
probably null |
|
|
R5809:Ubr3
|
UTSW |
2 |
69,795,855 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5913:Ubr3
|
UTSW |
2 |
69,851,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5969:Ubr3
|
UTSW |
2 |
69,809,730 (GRCm39) |
nonsense |
probably null |
|
|
R6136:Ubr3
|
UTSW |
2 |
69,824,107 (GRCm39) |
missense |
probably benign |
0.26 |
|
R6140:Ubr3
|
UTSW |
2 |
69,803,673 (GRCm39) |
missense |
probably benign |
0.09 |
|
R6185:Ubr3
|
UTSW |
2 |
69,768,621 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6220:Ubr3
|
UTSW |
2 |
69,850,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6258:Ubr3
|
UTSW |
2 |
69,813,208 (GRCm39) |
splice site |
probably null |
|
|
R6319:Ubr3
|
UTSW |
2 |
69,803,758 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6322:Ubr3
|
UTSW |
2 |
69,786,429 (GRCm39) |
nonsense |
probably null |
|
|
R6470:Ubr3
|
UTSW |
2 |
69,795,804 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6477:Ubr3
|
UTSW |
2 |
69,809,773 (GRCm39) |
nonsense |
probably null |
|
|
R6702:Ubr3
|
UTSW |
2 |
69,786,393 (GRCm39) |
missense |
probably benign |
0.23 |
|
R6709:Ubr3
|
UTSW |
2 |
69,843,436 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6803:Ubr3
|
UTSW |
2 |
69,766,368 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6806:Ubr3
|
UTSW |
2 |
69,786,308 (GRCm39) |
splice site |
probably benign |
|
|
R6834:Ubr3
|
UTSW |
2 |
69,830,825 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6841:Ubr3
|
UTSW |
2 |
69,850,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6847:Ubr3
|
UTSW |
2 |
69,813,472 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6889:Ubr3
|
UTSW |
2 |
69,774,644 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R7065:Ubr3
|
UTSW |
2 |
69,784,049 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7102:Ubr3
|
UTSW |
2 |
69,728,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7156:Ubr3
|
UTSW |
2 |
69,851,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7209:Ubr3
|
UTSW |
2 |
69,846,478 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7273:Ubr3
|
UTSW |
2 |
69,809,677 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7314:Ubr3
|
UTSW |
2 |
69,821,944 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7422:Ubr3
|
UTSW |
2 |
69,783,886 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7584:Ubr3
|
UTSW |
2 |
69,821,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7588:Ubr3
|
UTSW |
2 |
69,801,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7597:Ubr3
|
UTSW |
2 |
69,803,812 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7697:Ubr3
|
UTSW |
2 |
69,728,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7737:Ubr3
|
UTSW |
2 |
69,821,910 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7743:Ubr3
|
UTSW |
2 |
69,774,793 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7946:Ubr3
|
UTSW |
2 |
69,781,739 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7991:Ubr3
|
UTSW |
2 |
69,783,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8071:Ubr3
|
UTSW |
2 |
69,819,220 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8136:Ubr3
|
UTSW |
2 |
69,851,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8296:Ubr3
|
UTSW |
2 |
69,784,706 (GRCm39) |
missense |
probably null |
1.00 |
|
R8313:Ubr3
|
UTSW |
2 |
69,775,478 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8675:Ubr3
|
UTSW |
2 |
69,850,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8834:Ubr3
|
UTSW |
2 |
69,833,785 (GRCm39) |
missense |
probably benign |
|
|
R8975:Ubr3
|
UTSW |
2 |
69,752,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9060:Ubr3
|
UTSW |
2 |
69,839,489 (GRCm39) |
nonsense |
probably null |
|
|
R9153:Ubr3
|
UTSW |
2 |
69,795,822 (GRCm39) |
missense |
|
|
|
R9234:Ubr3
|
UTSW |
2 |
69,727,990 (GRCm39) |
missense |
probably benign |
|
|
R9293:Ubr3
|
UTSW |
2 |
69,727,769 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9312:Ubr3
|
UTSW |
2 |
69,784,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9710:Ubr3
|
UTSW |
2 |
69,727,957 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9762:Ubr3
|
UTSW |
2 |
69,839,497 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1088:Ubr3
|
UTSW |
2 |
69,752,711 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Ubr3
|
UTSW |
2 |
69,803,550 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Ubr3
|
UTSW |
2 |
69,728,010 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Ubr3
|
UTSW |
2 |
69,727,805 (GRCm39) |
missense |
probably benign |
0.17 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTGACTGAGACTTTGCAACAATTAC -3'
(R):5'- GGATTTTGAACACACTGACCAATC -3'
Sequencing Primer
(F):5'- GCTGCATAAACTGTGATTTTTGC -3'
(R):5'- TGACCAATCACAAAACAGAAAAGG -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation