Incidental Mutation 'R8317:Foxp1'
| ID |
641742 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Foxp1
|
| Ensembl Gene |
ENSMUSG00000030067 |
| Gene Name |
forkhead box P1 |
| Synonyms |
3110052D19Rik, 4932443N09Rik |
| MMRRC Submission |
067721-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R8317 (G1)
|
| Quality Score |
115.467 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
98902299-99499682 bp(-) (GRCm39) |
| Type of Mutation |
small deletion (1 aa in frame mutation) |
| DNA Base Change (assembly) |
TTGCTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGTTGCTGCTGCTGTTGCTGCTGTTGCTGCTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGCTGCTGCTG to TTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGTTGCTGCTGCTGTTGCTGCTGTTGCTGCTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGCTGCTGCTG
at 99052866 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000135764
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000074346]
[ENSMUST00000113322]
[ENSMUST00000113324]
[ENSMUST00000113326]
[ENSMUST00000113328]
[ENSMUST00000113329]
[ENSMUST00000175886]
[ENSMUST00000176565]
[ENSMUST00000176632]
[ENSMUST00000176850]
[ENSMUST00000177208]
[ENSMUST00000177230]
[ENSMUST00000177307]
|
| AlphaFold |
P58462 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000074346
|
| SMART Domains |
Protein: ENSMUSP00000073953
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
233 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
250 |
N/A |
INTRINSIC |
|
low complexity region
|
264 |
275 |
N/A |
INTRINSIC |
|
low complexity region
|
317 |
330 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
334 |
359 |
8.67e-1 |
SMART |
|
low complexity region
|
371 |
383 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
446 |
N/A |
INTRINSIC |
|
FH
|
491 |
572 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113322
|
| SMART Domains |
Protein: ENSMUSP00000108948
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
233 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
250 |
N/A |
INTRINSIC |
|
low complexity region
|
264 |
275 |
N/A |
INTRINSIC |
|
low complexity region
|
317 |
330 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
334 |
359 |
8.67e-1 |
SMART |
|
low complexity region
|
371 |
383 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
446 |
N/A |
INTRINSIC |
|
FH
|
491 |
572 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113324
|
| SMART Domains |
Protein: ENSMUSP00000108950
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
201 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
237 |
251 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
318 |
331 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
335 |
360 |
8.67e-1 |
SMART |
|
low complexity region
|
372 |
384 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
FH
|
492 |
573 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113326
|
| SMART Domains |
Protein: ENSMUSP00000108952
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
108 |
159 |
N/A |
INTRINSIC |
|
low complexity region
|
168 |
201 |
N/A |
INTRINSIC |
|
low complexity region
|
204 |
218 |
N/A |
INTRINSIC |
|
low complexity region
|
232 |
243 |
N/A |
INTRINSIC |
|
low complexity region
|
285 |
298 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
302 |
327 |
8.67e-1 |
SMART |
|
low complexity region
|
339 |
351 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
414 |
N/A |
INTRINSIC |
|
FH
|
459 |
540 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113328
|
| SMART Domains |
Protein: ENSMUSP00000108954
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
237 |
251 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
318 |
331 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
335 |
360 |
8.67e-1 |
SMART |
|
low complexity region
|
372 |
384 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
FH
|
492 |
573 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113329
|
| SMART Domains |
Protein: ENSMUSP00000108955
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
233 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
250 |
N/A |
INTRINSIC |
|
low complexity region
|
264 |
275 |
N/A |
INTRINSIC |
|
low complexity region
|
317 |
330 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
334 |
359 |
8.67e-1 |
SMART |
|
low complexity region
|
371 |
383 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
446 |
N/A |
INTRINSIC |
|
FH
|
491 |
579 |
1.76e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000175886
|
| SMART Domains |
Protein: ENSMUSP00000135517
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
10 |
62 |
N/A |
INTRINSIC |
|
low complexity region
|
71 |
105 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176565
|
| SMART Domains |
Protein: ENSMUSP00000135181
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
237 |
251 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
318 |
331 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
335 |
360 |
8.67e-1 |
SMART |
|
low complexity region
|
372 |
384 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
FH
|
491 |
572 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176632
|
| SMART Domains |
Protein: ENSMUSP00000135635
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
108 |
159 |
N/A |
INTRINSIC |
|
low complexity region
|
168 |
202 |
N/A |
INTRINSIC |
|
low complexity region
|
205 |
219 |
N/A |
INTRINSIC |
|
low complexity region
|
233 |
244 |
N/A |
INTRINSIC |
|
low complexity region
|
286 |
299 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
303 |
328 |
8.67e-1 |
SMART |
|
low complexity region
|
340 |
352 |
N/A |
INTRINSIC |
|
low complexity region
|
401 |
415 |
N/A |
INTRINSIC |
|
FH
|
460 |
541 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176850
|
| SMART Domains |
Protein: ENSMUSP00000135041
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
108 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
169 |
203 |
N/A |
INTRINSIC |
|
low complexity region
|
206 |
220 |
N/A |
INTRINSIC |
|
low complexity region
|
234 |
245 |
N/A |
INTRINSIC |
|
low complexity region
|
287 |
300 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
304 |
329 |
8.67e-1 |
SMART |
|
low complexity region
|
341 |
353 |
N/A |
INTRINSIC |
|
low complexity region
|
402 |
416 |
N/A |
INTRINSIC |
|
FH
|
461 |
542 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177208
|
| SMART Domains |
Protein: ENSMUSP00000135187
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
88 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177230
|
| SMART Domains |
Protein: ENSMUSP00000135098
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
108 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
169 |
203 |
N/A |
INTRINSIC |
|
low complexity region
|
206 |
220 |
N/A |
INTRINSIC |
|
low complexity region
|
234 |
245 |
N/A |
INTRINSIC |
|
low complexity region
|
287 |
300 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
304 |
329 |
8.67e-1 |
SMART |
|
low complexity region
|
341 |
353 |
N/A |
INTRINSIC |
|
low complexity region
|
402 |
416 |
N/A |
INTRINSIC |
|
FH
|
461 |
542 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177307
|
| SMART Domains |
Protein: ENSMUSP00000135764
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
201 |
235 |
N/A |
INTRINSIC |
|
low complexity region
|
238 |
252 |
N/A |
INTRINSIC |
|
low complexity region
|
266 |
277 |
N/A |
INTRINSIC |
|
low complexity region
|
319 |
332 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
336 |
361 |
8.67e-1 |
SMART |
|
low complexity region
|
373 |
385 |
N/A |
INTRINSIC |
|
low complexity region
|
434 |
448 |
N/A |
INTRINSIC |
|
FH
|
492 |
573 |
2.07e-39 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygous null mice display embryonic lethality with abnormal outflow tract septation, ventricular septal defects, abnormal cardiac valve morphology, decreased and irregular heart rate, thin ventricular compact zone, and edema. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 60 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adgrv1 |
C |
T |
13: 81,723,236 (GRCm39) |
V621M |
probably damaging |
Het |
| Adipor1 |
C |
T |
1: 134,355,905 (GRCm39) |
R235W |
probably benign |
Het |
| Agbl1 |
T |
A |
7: 76,071,929 (GRCm39) |
M594K |
unknown |
Het |
| Ang2 |
A |
G |
14: 51,433,349 (GRCm39) |
V11A |
probably benign |
Het |
| Ccl25 |
A |
G |
8: 4,404,138 (GRCm39) |
N80S |
probably benign |
Het |
| Cd19 |
A |
T |
7: 126,012,615 (GRCm39) |
C259* |
probably null |
Het |
| Cd209b |
A |
T |
8: 3,972,018 (GRCm39) |
I177N |
probably damaging |
Het |
| Cdc20 |
C |
A |
4: 118,294,323 (GRCm39) |
|
probably benign |
Het |
| Cdh23 |
A |
T |
10: 60,147,037 (GRCm39) |
|
probably null |
Het |
| Cdh23 |
G |
A |
10: 60,272,568 (GRCm39) |
R536W |
probably damaging |
Het |
| Cfap299 |
A |
C |
5: 98,885,459 (GRCm39) |
H122P |
probably benign |
Het |
| Chd6 |
T |
C |
2: 160,832,241 (GRCm39) |
D977G |
probably damaging |
Het |
| Cilk1 |
T |
A |
9: 78,060,933 (GRCm39) |
V193E |
probably damaging |
Het |
| Csl |
T |
G |
10: 99,594,900 (GRCm39) |
H55P |
probably damaging |
Het |
| Cstf2t |
G |
A |
19: 31,061,648 (GRCm39) |
A395T |
probably benign |
Het |
| Dhx58 |
A |
T |
11: 100,594,388 (GRCm39) |
I101N |
probably damaging |
Het |
| Dlg5 |
A |
C |
14: 24,241,298 (GRCm39) |
S200A |
probably damaging |
Het |
| Epb41 |
C |
A |
4: 131,684,961 (GRCm39) |
G86V |
|
Het |
| Fat4 |
T |
C |
3: 39,012,659 (GRCm39) |
V2318A |
possibly damaging |
Het |
| Fbxo32 |
A |
T |
15: 58,068,626 (GRCm39) |
F119I |
probably damaging |
Het |
| Flacc1 |
T |
C |
1: 58,715,707 (GRCm39) |
K170E |
possibly damaging |
Het |
| Fndc1 |
A |
T |
17: 8,019,720 (GRCm39) |
L153* |
probably null |
Het |
| Gm4559 |
CTGCAGCAGCTGGACTGACAGCAGCAGGGCTTGCAGCAGCTGGACTGACAGCAGCAGGGCTTGCAGCAGCTGGACTGACAACAGCAGGGCTTGCAACAGCTGGACTGGCAGCAGCAGGGCTTGCAGCAGCT |
CTGCAGCAGCTGGACTGACAGCAGCAGGGCTTGCAGCAGCTGGACTGACAACAGCAGGGCTTGCAACAGCTGGACTGGCAGCAGCAGGGCTTGCAGCAGCT |
7: 141,827,553 (GRCm39) |
|
probably benign |
Het |
| Gpr63 |
A |
T |
4: 25,008,223 (GRCm39) |
T316S |
probably damaging |
Het |
| Il16 |
T |
C |
7: 83,304,538 (GRCm39) |
T665A |
probably benign |
Het |
| Lama5 |
T |
C |
2: 179,848,784 (GRCm39) |
N272S |
probably damaging |
Het |
| Map3k1 |
T |
C |
13: 111,894,696 (GRCm39) |
Y660C |
probably damaging |
Het |
| Mbd3l1 |
C |
A |
9: 18,396,117 (GRCm39) |
L81I |
probably benign |
Het |
| Morc3 |
C |
A |
16: 93,659,417 (GRCm39) |
Q442K |
probably benign |
Het |
| Muc16 |
G |
A |
9: 18,569,339 (GRCm39) |
T1060I |
unknown |
Het |
| Myh11 |
T |
A |
16: 14,025,941 (GRCm39) |
D1343V |
|
Het |
| Myh15 |
C |
A |
16: 48,940,381 (GRCm39) |
T777N |
probably damaging |
Het |
| Nbn |
T |
G |
4: 15,970,893 (GRCm39) |
L292W |
probably damaging |
Het |
| Ndufb11b |
A |
G |
15: 81,864,978 (GRCm39) |
Y73C |
probably damaging |
Het |
| Nebl |
A |
G |
2: 17,355,568 (GRCm39) |
M195T |
possibly damaging |
Het |
| Net1 |
T |
C |
13: 3,957,856 (GRCm39) |
K66E |
possibly damaging |
Het |
| Nod1 |
T |
C |
6: 54,920,425 (GRCm39) |
Y631C |
probably damaging |
Het |
| Nxf1 |
A |
G |
19: 8,748,407 (GRCm39) |
H12R |
probably benign |
Het |
| Onecut3 |
T |
C |
10: 80,331,161 (GRCm39) |
L107P |
unknown |
Het |
| Opa1 |
T |
G |
16: 29,432,962 (GRCm39) |
I512S |
probably damaging |
Het |
| P3h3 |
C |
T |
6: 124,832,116 (GRCm39) |
G257R |
probably damaging |
Het |
| Pappa2 |
A |
G |
1: 158,592,530 (GRCm39) |
C1616R |
probably damaging |
Het |
| Parn |
T |
G |
16: 13,358,964 (GRCm39) |
K593Q |
probably damaging |
Het |
| Pcare |
A |
C |
17: 72,056,197 (GRCm39) |
L1160R |
probably benign |
Het |
| Polr3g |
T |
C |
13: 81,826,302 (GRCm39) |
K173R |
unknown |
Het |
| Prcp |
A |
G |
7: 92,524,598 (GRCm39) |
T18A |
probably benign |
Het |
| Sash1 |
G |
A |
10: 8,605,150 (GRCm39) |
T1080M |
possibly damaging |
Het |
| Skap2 |
A |
G |
6: 51,884,865 (GRCm39) |
|
probably null |
Het |
| Spmip9 |
C |
A |
6: 70,890,276 (GRCm39) |
W172L |
possibly damaging |
Het |
| Srebf1 |
C |
A |
11: 60,091,483 (GRCm39) |
S1014I |
possibly damaging |
Het |
| Stk32b |
C |
T |
5: 37,612,319 (GRCm39) |
E356K |
probably damaging |
Het |
| Tjp3 |
T |
A |
10: 81,116,324 (GRCm39) |
T257S |
probably benign |
Het |
| Trf |
A |
G |
9: 103,094,715 (GRCm39) |
Y448H |
probably damaging |
Het |
| Tsnaxip1 |
G |
C |
8: 106,554,438 (GRCm39) |
R7P |
probably benign |
Het |
| Vmn1r208 |
G |
C |
13: 22,956,947 (GRCm39) |
I183M |
probably benign |
Het |
| Vmn2r67 |
T |
A |
7: 84,785,834 (GRCm39) |
M724L |
probably benign |
Het |
| Wdhd1 |
A |
T |
14: 47,500,994 (GRCm39) |
H469Q |
probably damaging |
Het |
| Zbtb7a |
G |
C |
10: 80,980,784 (GRCm39) |
G326A |
probably benign |
Het |
| Zfp493 |
G |
A |
13: 67,931,958 (GRCm39) |
R19H |
probably benign |
Het |
| Zfp932 |
A |
T |
5: 110,156,922 (GRCm39) |
K207* |
probably null |
Het |
|
| Other mutations in Foxp1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02191:Foxp1
|
APN |
6 |
98,922,561 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02330:Foxp1
|
APN |
6 |
98,922,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02869:Foxp1
|
APN |
6 |
98,907,044 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL02968:Foxp1
|
APN |
6 |
99,052,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Foxy
|
UTSW |
6 |
98,992,471 (GRCm39) |
nonsense |
probably null |
|
|
Moxie
|
UTSW |
6 |
98,992,475 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Roxie
|
UTSW |
6 |
98,918,595 (GRCm39) |
missense |
unknown |
|
|
R0037:Foxp1
|
UTSW |
6 |
99,139,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0063:Foxp1
|
UTSW |
6 |
98,921,684 (GRCm39) |
splice site |
probably benign |
|
|
R0063:Foxp1
|
UTSW |
6 |
98,921,684 (GRCm39) |
splice site |
probably benign |
|
|
R0427:Foxp1
|
UTSW |
6 |
98,907,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0601:Foxp1
|
UTSW |
6 |
98,907,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1356:Foxp1
|
UTSW |
6 |
98,993,637 (GRCm39) |
splice site |
probably benign |
|
|
R1468:Foxp1
|
UTSW |
6 |
98,955,181 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1468:Foxp1
|
UTSW |
6 |
98,955,181 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1548:Foxp1
|
UTSW |
6 |
98,922,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1696:Foxp1
|
UTSW |
6 |
98,922,663 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1933:Foxp1
|
UTSW |
6 |
99,052,926 (GRCm39) |
small deletion |
probably benign |
|
|
R2152:Foxp1
|
UTSW |
6 |
98,993,502 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2338:Foxp1
|
UTSW |
6 |
98,980,254 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R3896:Foxp1
|
UTSW |
6 |
99,052,897 (GRCm39) |
missense |
probably benign |
0.33 |
|
R5006:Foxp1
|
UTSW |
6 |
99,139,819 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5143:Foxp1
|
UTSW |
6 |
98,922,493 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5428:Foxp1
|
UTSW |
6 |
98,993,592 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5765:Foxp1
|
UTSW |
6 |
98,992,423 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5816:Foxp1
|
UTSW |
6 |
99,052,926 (GRCm39) |
small deletion |
probably benign |
|
|
R6172:Foxp1
|
UTSW |
6 |
98,992,475 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6172:Foxp1
|
UTSW |
6 |
98,992,471 (GRCm39) |
nonsense |
probably null |
|
|
R6173:Foxp1
|
UTSW |
6 |
98,992,475 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6173:Foxp1
|
UTSW |
6 |
98,992,471 (GRCm39) |
nonsense |
probably null |
|
|
R6175:Foxp1
|
UTSW |
6 |
98,943,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6776:Foxp1
|
UTSW |
6 |
99,052,926 (GRCm39) |
small deletion |
probably benign |
|
|
R6782:Foxp1
|
UTSW |
6 |
98,907,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7229:Foxp1
|
UTSW |
6 |
98,912,373 (GRCm39) |
missense |
unknown |
|
|
R7559:Foxp1
|
UTSW |
6 |
98,922,521 (GRCm39) |
missense |
unknown |
|
|
R7715:Foxp1
|
UTSW |
6 |
98,922,621 (GRCm39) |
missense |
unknown |
|
|
R8007:Foxp1
|
UTSW |
6 |
98,918,595 (GRCm39) |
missense |
unknown |
|
|
R8099:Foxp1
|
UTSW |
6 |
98,922,510 (GRCm39) |
missense |
unknown |
|
|
R8408:Foxp1
|
UTSW |
6 |
98,922,543 (GRCm39) |
missense |
unknown |
|
|
R8704:Foxp1
|
UTSW |
6 |
98,993,507 (GRCm39) |
missense |
unknown |
|
|
R8705:Foxp1
|
UTSW |
6 |
98,993,507 (GRCm39) |
missense |
unknown |
|
|
R9014:Foxp1
|
UTSW |
6 |
99,052,866 (GRCm39) |
small deletion |
probably benign |
|
|
R9147:Foxp1
|
UTSW |
6 |
99,052,866 (GRCm39) |
small deletion |
probably benign |
|
|
R9399:Foxp1
|
UTSW |
6 |
99,052,866 (GRCm39) |
small deletion |
probably benign |
|
|
R9604:Foxp1
|
UTSW |
6 |
99,052,926 (GRCm39) |
small deletion |
probably benign |
|
|
X0066:Foxp1
|
UTSW |
6 |
99,052,976 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Foxp1
|
UTSW |
6 |
98,955,122 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TAGCATGCTGGATTCTTCCC -3'
(R):5'- TCTCCAGACCTGTGTGATAATG -3'
Sequencing Primer
(F):5'- GAAACTTCTGGTCAAAGAGACTTTTC -3'
(R):5'- CTCCAGACCTGTGTGATAATGAAATC -3'
|
| Posted On |
2020-07-28 |
Incidental Mutation