Incidental Mutation 'R8859:Rictor'
| ID |
675572 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rictor
|
| Ensembl Gene |
ENSMUSG00000050310 |
| Gene Name |
RPTOR independent companion of MTOR, complex 2 |
| Synonyms |
D530039E11Rik, 4921505C17Rik, 6030405M08Rik |
| MMRRC Submission |
068739-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R8859 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
6737860-6829882 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 6813067 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Arginine
at position 940
(L940R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000051809
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000061656]
|
| AlphaFold |
Q6QI06 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000061656
AA Change: L940R
PolyPhen 2
Score 0.976 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000051809
Gene: ENSMUSG00000050310
AA Change: L940R
| Domain | Start | End | E-Value | Type |
|---|
|
RICTOR_N
|
57 |
439 |
4.02e-185 |
SMART |
|
RICTOR_M
|
523 |
742 |
5.66e-98 |
SMART |
|
RasGEF_N_2
|
743 |
857 |
1.26e-54 |
SMART |
|
RICTOR_V
|
920 |
992 |
1.44e-40 |
SMART |
|
low complexity region
|
1019 |
1043 |
N/A |
INTRINSIC |
|
RICTOR_phospho
|
1084 |
1189 |
4.06e-58 |
SMART |
|
low complexity region
|
1221 |
1239 |
N/A |
INTRINSIC |
|
low complexity region
|
1255 |
1266 |
N/A |
INTRINSIC |
|
low complexity region
|
1273 |
1287 |
N/A |
INTRINSIC |
|
low complexity region
|
1404 |
1414 |
N/A |
INTRINSIC |
|
low complexity region
|
1464 |
1474 |
N/A |
INTRINSIC |
|
low complexity region
|
1616 |
1628 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.8348 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
99% (95/96) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality during organogenesis associated with abnormal placental morphology. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca13 |
A |
T |
11: 9,328,397 (GRCm39) |
Y3490F |
|
Het |
| Abcc1 |
T |
C |
16: 14,214,225 (GRCm39) |
V167A |
probably benign |
Het |
| Abcd2 |
G |
A |
15: 91,073,149 (GRCm39) |
R337C |
probably damaging |
Het |
| Adcy1 |
A |
G |
11: 7,111,877 (GRCm39) |
D914G |
probably benign |
Het |
| Ahnak |
G |
T |
19: 8,984,567 (GRCm39) |
L1950F |
probably damaging |
Het |
| Alox5ap |
T |
C |
5: 149,201,994 (GRCm39) |
|
probably null |
Het |
| Ank |
C |
T |
15: 27,562,834 (GRCm39) |
H181Y |
possibly damaging |
Het |
| Ankrd44 |
T |
A |
1: 54,706,680 (GRCm39) |
D592V |
possibly damaging |
Het |
| Ap4m1 |
T |
A |
5: 138,174,185 (GRCm39) |
N185K |
possibly damaging |
Het |
| Arhgef28 |
T |
A |
13: 98,082,210 (GRCm39) |
D1199V |
probably damaging |
Het |
| Arnt |
T |
C |
3: 95,397,691 (GRCm39) |
|
probably null |
Het |
| Atcay |
C |
T |
10: 81,060,298 (GRCm39) |
V13M |
probably benign |
Het |
| B4galt3 |
T |
C |
1: 171,099,241 (GRCm39) |
S2P |
unknown |
Het |
| Bicra |
A |
T |
7: 15,721,737 (GRCm39) |
S593R |
possibly damaging |
Het |
| Brsk2 |
A |
C |
7: 141,552,415 (GRCm39) |
Q633P |
probably damaging |
Het |
| Cacna1c |
T |
A |
6: 118,653,280 (GRCm39) |
S909C |
|
Het |
| Ccdc7a |
G |
A |
8: 129,788,113 (GRCm39) |
T72M |
probably benign |
Het |
| Ccn1 |
T |
C |
3: 145,354,380 (GRCm39) |
D177G |
probably benign |
Het |
| Cct2 |
A |
T |
10: 116,896,739 (GRCm39) |
F155I |
possibly damaging |
Het |
| Cdv3 |
G |
T |
9: 103,233,594 (GRCm39) |
P194T |
probably damaging |
Het |
| Cenpc1 |
A |
T |
5: 86,160,153 (GRCm39) |
V895E |
probably benign |
Het |
| Cep170b |
T |
C |
12: 112,702,881 (GRCm39) |
V448A |
probably benign |
Het |
| Chil3 |
G |
A |
3: 106,071,440 (GRCm39) |
R75C |
possibly damaging |
Het |
| Cnfn |
A |
T |
7: 25,067,869 (GRCm39) |
C24S |
probably benign |
Het |
| Cnga3 |
A |
G |
1: 37,299,852 (GRCm39) |
K191E |
possibly damaging |
Het |
| Col12a1 |
A |
T |
9: 79,587,681 (GRCm39) |
Y1153* |
probably null |
Het |
| Coq4 |
C |
A |
2: 29,685,491 (GRCm39) |
H168Q |
probably damaging |
Het |
| Dennd2b |
T |
A |
7: 109,123,863 (GRCm39) |
K1132M |
probably damaging |
Het |
| Dnajc14 |
G |
A |
10: 128,642,488 (GRCm39) |
V137I |
probably benign |
Het |
| Efr3a |
T |
C |
15: 65,726,614 (GRCm39) |
L569P |
probably damaging |
Het |
| Epb41l3 |
A |
T |
17: 69,591,575 (GRCm39) |
E677D |
probably benign |
Het |
| Esp8 |
G |
A |
17: 40,841,013 (GRCm39) |
M91I |
unknown |
Het |
| Fubp1 |
A |
T |
3: 151,937,669 (GRCm39) |
|
probably benign |
Het |
| Gldc |
G |
T |
19: 30,116,779 (GRCm39) |
A391D |
probably damaging |
Het |
| Gm17728 |
A |
G |
17: 9,641,027 (GRCm39) |
T46A |
probably benign |
Het |
| Gm5798 |
A |
G |
14: 41,072,603 (GRCm39) |
K112E |
probably damaging |
Het |
| Gpnmb |
A |
G |
6: 49,028,964 (GRCm39) |
|
probably benign |
Het |
| Grwd1 |
T |
C |
7: 45,475,298 (GRCm39) |
T415A |
probably benign |
Het |
| Gsdma3 |
C |
G |
11: 98,522,086 (GRCm39) |
A172G |
possibly damaging |
Het |
| Hltf |
C |
T |
3: 20,119,566 (GRCm39) |
Q204* |
probably null |
Het |
| Igf1r |
T |
G |
7: 67,833,211 (GRCm39) |
V457G |
possibly damaging |
Het |
| Inhbc |
A |
T |
10: 127,192,984 (GRCm39) |
M344K |
probably damaging |
Het |
| Jak3 |
C |
T |
8: 72,131,160 (GRCm39) |
A60V |
probably benign |
Het |
| Kif13b |
A |
G |
14: 64,979,882 (GRCm39) |
T511A |
probably benign |
Het |
| Lama2 |
T |
A |
10: 27,335,384 (GRCm39) |
N97I |
possibly damaging |
Het |
| Limd2 |
T |
A |
11: 106,049,576 (GRCm39) |
D104V |
probably damaging |
Het |
| Loxl3 |
T |
A |
6: 83,014,526 (GRCm39) |
C145S |
probably damaging |
Het |
| Lrrc37 |
A |
C |
11: 103,506,370 (GRCm39) |
I1866S |
unknown |
Het |
| Lrrc73 |
A |
G |
17: 46,565,455 (GRCm39) |
N62S |
probably benign |
Het |
| Lrrtm4 |
A |
G |
6: 79,998,870 (GRCm39) |
D94G |
probably damaging |
Het |
| Lsm3 |
C |
A |
6: 91,499,252 (GRCm39) |
F86L |
probably damaging |
Het |
| Map10 |
T |
C |
8: 126,397,291 (GRCm39) |
V228A |
probably benign |
Het |
| Mcidas |
A |
C |
13: 113,130,664 (GRCm39) |
S54R |
possibly damaging |
Het |
| Me3 |
T |
C |
7: 89,455,876 (GRCm39) |
Y243H |
probably damaging |
Het |
| Mgat4b |
A |
G |
11: 50,121,674 (GRCm39) |
T89A |
possibly damaging |
Het |
| Mmp16 |
T |
A |
4: 18,054,355 (GRCm39) |
|
probably benign |
Het |
| Mtmr9 |
G |
A |
14: 63,781,226 (GRCm39) |
|
probably benign |
Het |
| Myo1b |
G |
T |
1: 51,836,198 (GRCm39) |
A331E |
probably damaging |
Het |
| Ncoa6 |
C |
T |
2: 155,248,388 (GRCm39) |
V1639M |
possibly damaging |
Het |
| Nek9 |
C |
T |
12: 85,353,120 (GRCm39) |
G752R |
probably damaging |
Het |
| Nufip2 |
A |
G |
11: 77,584,069 (GRCm39) |
Y661C |
probably benign |
Het |
| Or10w1 |
T |
A |
19: 13,632,246 (GRCm39) |
V151E |
probably damaging |
Het |
| Or1n2 |
C |
T |
2: 36,797,516 (GRCm39) |
A186V |
possibly damaging |
Het |
| Or51t4 |
A |
T |
7: 102,598,373 (GRCm39) |
I234F |
probably damaging |
Het |
| Or7g16 |
T |
C |
9: 18,726,992 (GRCm39) |
I199M |
possibly damaging |
Het |
| Or8g55 |
G |
A |
9: 39,784,894 (GRCm39) |
G108S |
probably benign |
Het |
| Oxct2a |
A |
G |
4: 123,216,322 (GRCm39) |
L353S |
probably benign |
Het |
| Parvg |
A |
G |
15: 84,222,001 (GRCm39) |
I243V |
probably benign |
Het |
| Pcdhgb7 |
C |
A |
18: 37,886,349 (GRCm39) |
N506K |
possibly damaging |
Het |
| Peg10 |
T |
TCCA |
6: 4,756,451 (GRCm39) |
|
probably benign |
Het |
| Pgghg |
G |
A |
7: 140,525,367 (GRCm39) |
|
probably null |
Het |
| Phrf1 |
G |
T |
7: 140,836,516 (GRCm39) |
G263W |
unknown |
Het |
| Ppfia1 |
A |
C |
7: 144,032,762 (GRCm39) |
|
probably null |
Het |
| Prss37 |
T |
A |
6: 40,491,897 (GRCm39) |
I228F |
probably damaging |
Het |
| Ptpro |
A |
T |
6: 137,403,782 (GRCm39) |
K921* |
probably null |
Het |
| Rp1 |
A |
G |
1: 4,420,183 (GRCm39) |
S310P |
probably benign |
Het |
| Ryr3 |
A |
G |
2: 112,483,564 (GRCm39) |
V4091A |
probably damaging |
Het |
| Saxo4 |
T |
A |
19: 10,459,599 (GRCm39) |
Y36F |
probably damaging |
Het |
| Sirt5 |
T |
A |
13: 43,524,327 (GRCm39) |
M33K |
possibly damaging |
Het |
| Slc25a30 |
T |
A |
14: 76,008,917 (GRCm39) |
Y90F |
probably benign |
Het |
| Stimate |
T |
A |
14: 30,588,629 (GRCm39) |
Y119N |
probably damaging |
Het |
| Stk11 |
G |
A |
10: 79,964,269 (GRCm39) |
D388N |
probably benign |
Het |
| Tgm1 |
C |
A |
14: 55,949,686 (GRCm39) |
R126L |
probably benign |
Het |
| Tmem129 |
G |
T |
5: 33,811,837 (GRCm39) |
T321N |
probably benign |
Het |
| Tnfrsf11a |
A |
T |
1: 105,772,244 (GRCm39) |
|
probably null |
Het |
| Tor1aip1 |
A |
G |
1: 155,907,190 (GRCm39) |
C195R |
probably benign |
Het |
| Tpr |
A |
G |
1: 150,284,597 (GRCm39) |
E428G |
possibly damaging |
Het |
| Trps1 |
T |
A |
15: 50,685,769 (GRCm39) |
D802V |
possibly damaging |
Het |
| Usp17lc |
T |
A |
7: 103,064,316 (GRCm39) |
S6T |
probably benign |
Het |
| Vangl1 |
C |
A |
3: 102,065,758 (GRCm39) |
R459L |
|
Het |
| Vmn1r43 |
T |
C |
6: 89,846,937 (GRCm39) |
Y183C |
probably damaging |
Het |
| Vmn2r110 |
C |
T |
17: 20,794,560 (GRCm39) |
C703Y |
probably damaging |
Het |
| Vmn2r54 |
T |
C |
7: 12,363,702 (GRCm39) |
Q397R |
possibly damaging |
Het |
| Vmn2r88 |
T |
C |
14: 51,656,263 (GRCm39) |
V824A |
probably damaging |
Het |
| Vmn2r89 |
A |
T |
14: 51,693,170 (GRCm39) |
Y79F |
probably benign |
Het |
| Vnn1 |
T |
C |
10: 23,780,484 (GRCm39) |
S491P |
probably benign |
Het |
| Zbbx |
A |
G |
3: 74,968,741 (GRCm39) |
F572L |
unknown |
Het |
| Zc3h4 |
A |
T |
7: 16,168,939 (GRCm39) |
Q1091L |
unknown |
Het |
| Zfp503 |
C |
T |
14: 22,037,286 (GRCm39) |
V106I |
possibly damaging |
Het |
| Zfp874a |
T |
C |
13: 67,590,647 (GRCm39) |
T346A |
probably benign |
Het |
|
| Other mutations in Rictor |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00488:Rictor
|
APN |
15 |
6,816,071 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00785:Rictor
|
APN |
15 |
6,806,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00801:Rictor
|
APN |
15 |
6,824,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01072:Rictor
|
APN |
15 |
6,819,043 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01139:Rictor
|
APN |
15 |
6,807,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01303:Rictor
|
APN |
15 |
6,738,119 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL01307:Rictor
|
APN |
15 |
6,804,085 (GRCm39) |
splice site |
probably null |
|
|
IGL01767:Rictor
|
APN |
15 |
6,806,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01774:Rictor
|
APN |
15 |
6,799,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01800:Rictor
|
APN |
15 |
6,804,182 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02192:Rictor
|
APN |
15 |
6,815,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02503:Rictor
|
APN |
15 |
6,815,924 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02652:Rictor
|
APN |
15 |
6,805,668 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02656:Rictor
|
APN |
15 |
6,806,401 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02752:Rictor
|
APN |
15 |
6,816,852 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03000:Rictor
|
APN |
15 |
6,798,721 (GRCm39) |
splice site |
probably benign |
|
|
IGL03118:Rictor
|
APN |
15 |
6,788,999 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03182:Rictor
|
APN |
15 |
6,819,079 (GRCm39) |
missense |
probably benign |
0.08 |
|
Tense
|
UTSW |
15 |
6,788,977 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
Tonus
|
UTSW |
15 |
6,798,815 (GRCm39) |
critical splice donor site |
probably null |
|
|
Torrid
|
UTSW |
15 |
6,789,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0149:Rictor
|
UTSW |
15 |
6,813,588 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R0288:Rictor
|
UTSW |
15 |
6,816,021 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0304:Rictor
|
UTSW |
15 |
6,815,852 (GRCm39) |
splice site |
probably null |
|
|
R0336:Rictor
|
UTSW |
15 |
6,806,234 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0361:Rictor
|
UTSW |
15 |
6,813,588 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R0423:Rictor
|
UTSW |
15 |
6,803,381 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0453:Rictor
|
UTSW |
15 |
6,738,123 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0515:Rictor
|
UTSW |
15 |
6,798,782 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0630:Rictor
|
UTSW |
15 |
6,823,973 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0730:Rictor
|
UTSW |
15 |
6,803,467 (GRCm39) |
splice site |
probably benign |
|
|
R0744:Rictor
|
UTSW |
15 |
6,793,759 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0836:Rictor
|
UTSW |
15 |
6,793,759 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0881:Rictor
|
UTSW |
15 |
6,821,151 (GRCm39) |
missense |
probably benign |
|
|
R1114:Rictor
|
UTSW |
15 |
6,823,486 (GRCm39) |
nonsense |
probably null |
|
|
R1367:Rictor
|
UTSW |
15 |
6,820,119 (GRCm39) |
splice site |
probably benign |
|
|
R1655:Rictor
|
UTSW |
15 |
6,801,693 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1678:Rictor
|
UTSW |
15 |
6,785,952 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1679:Rictor
|
UTSW |
15 |
6,797,571 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1754:Rictor
|
UTSW |
15 |
6,764,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1757:Rictor
|
UTSW |
15 |
6,803,343 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1762:Rictor
|
UTSW |
15 |
6,786,054 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1914:Rictor
|
UTSW |
15 |
6,789,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1915:Rictor
|
UTSW |
15 |
6,789,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1994:Rictor
|
UTSW |
15 |
6,805,637 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2145:Rictor
|
UTSW |
15 |
6,794,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2182:Rictor
|
UTSW |
15 |
6,801,685 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2191:Rictor
|
UTSW |
15 |
6,789,095 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2357:Rictor
|
UTSW |
15 |
6,813,043 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2914:Rictor
|
UTSW |
15 |
6,799,476 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3082:Rictor
|
UTSW |
15 |
6,804,338 (GRCm39) |
missense |
probably benign |
0.15 |
|
R3885:Rictor
|
UTSW |
15 |
6,789,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3900:Rictor
|
UTSW |
15 |
6,818,954 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4376:Rictor
|
UTSW |
15 |
6,816,448 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4611:Rictor
|
UTSW |
15 |
6,816,625 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4644:Rictor
|
UTSW |
15 |
6,807,416 (GRCm39) |
nonsense |
probably null |
|
|
R4718:Rictor
|
UTSW |
15 |
6,812,641 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4822:Rictor
|
UTSW |
15 |
6,821,161 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4980:Rictor
|
UTSW |
15 |
6,811,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5034:Rictor
|
UTSW |
15 |
6,797,576 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5179:Rictor
|
UTSW |
15 |
6,825,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5386:Rictor
|
UTSW |
15 |
6,818,985 (GRCm39) |
missense |
probably benign |
0.37 |
|
R5532:Rictor
|
UTSW |
15 |
6,819,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5549:Rictor
|
UTSW |
15 |
6,816,391 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5715:Rictor
|
UTSW |
15 |
6,780,197 (GRCm39) |
nonsense |
probably null |
|
|
R5733:Rictor
|
UTSW |
15 |
6,812,585 (GRCm39) |
missense |
probably benign |
|
|
R5822:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5848:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5849:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5850:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5854:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5855:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5856:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5936:Rictor
|
UTSW |
15 |
6,813,642 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6155:Rictor
|
UTSW |
15 |
6,823,458 (GRCm39) |
missense |
probably benign |
0.44 |
|
R6394:Rictor
|
UTSW |
15 |
6,798,790 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R6549:Rictor
|
UTSW |
15 |
6,825,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6611:Rictor
|
UTSW |
15 |
6,780,140 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6657:Rictor
|
UTSW |
15 |
6,788,977 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6705:Rictor
|
UTSW |
15 |
6,823,493 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6819:Rictor
|
UTSW |
15 |
6,825,517 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6985:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6989:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7016:Rictor
|
UTSW |
15 |
6,804,361 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7030:Rictor
|
UTSW |
15 |
6,737,934 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7066:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7067:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7216:Rictor
|
UTSW |
15 |
6,798,782 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7396:Rictor
|
UTSW |
15 |
6,816,462 (GRCm39) |
missense |
not run |
|
|
R7449:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7450:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7452:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7616:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7620:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7643:Rictor
|
UTSW |
15 |
6,798,750 (GRCm39) |
nonsense |
probably null |
|
|
R7699:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7700:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7749:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7750:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7751:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7753:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7841:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7894:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7897:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7898:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7937:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7944:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8062:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8063:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8094:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8119:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8134:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8166:Rictor
|
UTSW |
15 |
6,798,815 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8324:Rictor
|
UTSW |
15 |
6,775,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8343:Rictor
|
UTSW |
15 |
6,807,800 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8691:Rictor
|
UTSW |
15 |
6,816,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8953:Rictor
|
UTSW |
15 |
6,823,928 (GRCm39) |
missense |
probably benign |
0.39 |
|
R8977:Rictor
|
UTSW |
15 |
6,812,566 (GRCm39) |
missense |
probably benign |
|
|
R9008:Rictor
|
UTSW |
15 |
6,801,610 (GRCm39) |
splice site |
probably benign |
|
|
R9369:Rictor
|
UTSW |
15 |
6,773,848 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9563:Rictor
|
UTSW |
15 |
6,797,562 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9695:Rictor
|
UTSW |
15 |
6,816,010 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0020:Rictor
|
UTSW |
15 |
6,785,963 (GRCm39) |
missense |
probably benign |
0.32 |
|
X0060:Rictor
|
UTSW |
15 |
6,816,033 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGGCCTTGGTCTGTAGTAAAC -3'
(R):5'- CAAGGCCATAGACTAGCACATTG -3'
Sequencing Primer
(F):5'- GTAGTAAACAGTTCTGGTCTTTCC -3'
(R):5'- GGCCATAGACTAGCACATTGAAATCG -3'
|
| Posted On |
2021-07-15 |
Incidental Mutation