Incidental Mutation 'R7780:Wdr90'
| ID |
599201 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Wdr90
|
| Ensembl Gene |
ENSMUSG00000073434 |
| Gene Name |
WD repeat domain 90 |
| Synonyms |
3230401M21Rik |
| MMRRC Submission |
045836-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.101)
|
| Stock # |
R7780 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
26063745-26080475 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 26065300 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Glutamine
at position 1652
(R1652Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000078426
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043897]
[ENSMUST00000079461]
[ENSMUST00000176709]
[ENSMUST00000176923]
|
| AlphaFold |
Q6ZPG2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000043897
|
| SMART Domains |
Protein: ENSMUSP00000044639
Gene: ENSMUSG00000025733
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Roc
|
6 |
122 |
4.1e-11 |
PFAM |
|
Pfam:Ras
|
6 |
168 |
2.3e-18 |
PFAM |
|
EFh
|
188 |
216 |
1.27e1 |
SMART |
|
Pfam:EF_assoc_2
|
219 |
305 |
2.2e-35 |
PFAM |
|
EFh
|
308 |
336 |
1.23e-1 |
SMART |
|
Pfam:EF_assoc_1
|
341 |
412 |
1.8e-25 |
PFAM |
|
Blast:AAA
|
416 |
547 |
7e-18 |
BLAST |
|
SCOP:d1mh1__
|
422 |
532 |
4e-8 |
SMART |
|
transmembrane domain
|
595 |
617 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000079461
AA Change: R1652Q
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000078426
Gene: ENSMUSG00000073434
AA Change: R1652Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
53 |
N/A |
INTRINSIC |
|
Pfam:DUF667
|
60 |
183 |
5e-26 |
PFAM |
|
Pfam:DUF667
|
210 |
271 |
3.7e-9 |
PFAM |
|
low complexity region
|
381 |
396 |
N/A |
INTRINSIC |
|
WD40
|
478 |
519 |
5.94e0 |
SMART |
|
WD40
|
522 |
565 |
3.2e0 |
SMART |
|
WD40
|
572 |
612 |
3.3e1 |
SMART |
|
WD40
|
687 |
725 |
1.15e1 |
SMART |
|
WD40
|
728 |
766 |
5.75e-1 |
SMART |
|
WD40
|
768 |
808 |
9.24e-4 |
SMART |
|
WD40
|
811 |
850 |
4.13e0 |
SMART |
|
WD40
|
853 |
892 |
4.62e-1 |
SMART |
|
WD40
|
950 |
993 |
1.07e1 |
SMART |
|
WD40
|
996 |
1035 |
5.75e-1 |
SMART |
|
WD40
|
1040 |
1077 |
1.58e-2 |
SMART |
|
WD40
|
1290 |
1334 |
5.23e-3 |
SMART |
|
WD40
|
1337 |
1378 |
1.27e-1 |
SMART |
|
WD40
|
1384 |
1419 |
1.83e2 |
SMART |
|
WD40
|
1422 |
1469 |
3.08e0 |
SMART |
|
WD40
|
1472 |
1509 |
9.9e0 |
SMART |
|
WD40
|
1568 |
1607 |
9.02e-7 |
SMART |
|
WD40
|
1610 |
1655 |
5.75e-1 |
SMART |
|
WD40
|
1659 |
1697 |
2.98e-1 |
SMART |
|
WD40
|
1700 |
1749 |
6.14e1 |
SMART |
|
WD40
|
1850 |
1888 |
1.92e-1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176591
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176709
|
| SMART Domains |
Protein: ENSMUSP00000135436
Gene: ENSMUSG00000025733
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Arf
|
1 |
121 |
1.6e-6 |
PFAM |
|
Pfam:MMR_HSR1
|
6 |
118 |
1.4e-6 |
PFAM |
|
Pfam:Miro
|
6 |
120 |
7.8e-20 |
PFAM |
|
Pfam:Ras
|
6 |
121 |
7.2e-16 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176751
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000176923
AA Change: R1634Q
PolyPhen 2
Score 0.930 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000135420
Gene: ENSMUSG00000073434
AA Change: R1634Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
53 |
N/A |
INTRINSIC |
|
Pfam:DUF667
|
60 |
252 |
5.1e-14 |
PFAM |
|
low complexity region
|
363 |
378 |
N/A |
INTRINSIC |
|
WD40
|
460 |
501 |
5.94e0 |
SMART |
|
WD40
|
504 |
547 |
3.2e0 |
SMART |
|
WD40
|
554 |
594 |
3.3e1 |
SMART |
|
WD40
|
669 |
707 |
1.15e1 |
SMART |
|
WD40
|
710 |
748 |
5.75e-1 |
SMART |
|
WD40
|
750 |
790 |
9.24e-4 |
SMART |
|
WD40
|
793 |
832 |
4.13e0 |
SMART |
|
WD40
|
835 |
874 |
4.62e-1 |
SMART |
|
WD40
|
932 |
975 |
1.07e1 |
SMART |
|
WD40
|
978 |
1017 |
5.75e-1 |
SMART |
|
WD40
|
1022 |
1059 |
1.58e-2 |
SMART |
|
WD40
|
1272 |
1316 |
5.23e-3 |
SMART |
|
WD40
|
1319 |
1360 |
1.27e-1 |
SMART |
|
WD40
|
1366 |
1401 |
1.83e2 |
SMART |
|
WD40
|
1404 |
1451 |
3.08e0 |
SMART |
|
WD40
|
1454 |
1491 |
9.9e0 |
SMART |
|
WD40
|
1550 |
1589 |
9.02e-7 |
SMART |
|
WD40
|
1592 |
1637 |
5.75e-1 |
SMART |
|
WD40
|
1641 |
1679 |
2.98e-1 |
SMART |
|
WD40
|
1682 |
1731 |
6.14e1 |
SMART |
|
WD40
|
1832 |
1870 |
1.92e-1 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.2%
|
| Validation Efficiency |
100% (77/77) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam5 |
C |
T |
8: 25,294,432 (GRCm39) |
R389K |
possibly damaging |
Het |
| Ahnak2 |
C |
T |
12: 112,746,716 (GRCm39) |
V1205M |
|
Het |
| Ccr3 |
A |
G |
9: 123,828,989 (GRCm39) |
Y108C |
probably benign |
Het |
| Cers5 |
T |
G |
15: 99,637,589 (GRCm39) |
H220P |
probably damaging |
Het |
| Cfap61 |
A |
T |
2: 145,995,692 (GRCm39) |
N1086Y |
possibly damaging |
Het |
| Cip2a |
T |
A |
16: 48,822,023 (GRCm39) |
L217* |
probably null |
Het |
| Clstn3 |
T |
C |
6: 124,439,161 (GRCm39) |
E32G |
probably damaging |
Het |
| Cox20 |
T |
C |
1: 178,149,566 (GRCm39) |
C72R |
probably benign |
Het |
| Csf1 |
A |
T |
3: 107,657,709 (GRCm39) |
N154K |
probably damaging |
Het |
| Cyp2j7 |
T |
A |
4: 96,118,256 (GRCm39) |
K112N |
probably benign |
Het |
| Drosha |
A |
G |
15: 12,848,172 (GRCm39) |
D488G |
probably benign |
Het |
| Edem1 |
A |
G |
6: 108,818,589 (GRCm39) |
K199R |
probably benign |
Het |
| Esyt2 |
T |
C |
12: 116,305,718 (GRCm39) |
I316T |
probably benign |
Het |
| Evpl |
C |
T |
11: 116,125,000 (GRCm39) |
R154H |
not run |
Het |
| Fbn1 |
A |
G |
2: 125,143,678 (GRCm39) |
L2817P |
probably benign |
Het |
| Fbxo42 |
T |
A |
4: 140,921,131 (GRCm39) |
|
probably null |
Het |
| Fbxo43 |
T |
C |
15: 36,162,358 (GRCm39) |
D283G |
probably damaging |
Het |
| Fdxr |
A |
T |
11: 115,167,656 (GRCm39) |
S20T |
probably benign |
Het |
| Fkbp10 |
T |
C |
11: 100,312,048 (GRCm39) |
Y203H |
probably damaging |
Het |
| Galntl6 |
C |
T |
8: 58,880,733 (GRCm39) |
|
probably null |
Het |
| Gask1b |
G |
A |
3: 79,848,711 (GRCm39) |
G486S |
probably damaging |
Het |
| Gm26657 |
C |
A |
4: 56,741,056 (GRCm39) |
Y80* |
probably null |
Het |
| Gm973 |
T |
A |
1: 59,597,289 (GRCm39) |
W440R |
probably damaging |
Het |
| Helz |
T |
A |
11: 107,528,689 (GRCm39) |
F903Y |
probably damaging |
Het |
| Iqcf4 |
T |
A |
9: 106,445,860 (GRCm39) |
I96F |
possibly damaging |
Het |
| Kcnq5 |
T |
A |
1: 22,031,555 (GRCm39) |
Q84L |
probably benign |
Het |
| Krit1 |
G |
A |
5: 3,862,772 (GRCm39) |
G254S |
probably damaging |
Het |
| Krtap6-2 |
A |
T |
16: 89,216,510 (GRCm39) |
Y152* |
probably null |
Het |
| Loricrin |
A |
T |
3: 91,988,460 (GRCm39) |
Y275* |
probably null |
Het |
| Map4 |
T |
C |
9: 109,863,720 (GRCm39) |
I315T |
probably benign |
Het |
| Mcpt1 |
T |
A |
14: 56,256,609 (GRCm39) |
|
probably null |
Het |
| Mdh1b |
C |
A |
1: 63,759,133 (GRCm39) |
S153I |
possibly damaging |
Het |
| Mfsd12 |
C |
A |
10: 81,193,718 (GRCm39) |
A96E |
probably benign |
Het |
| Mki67 |
T |
C |
7: 135,315,697 (GRCm39) |
E55G |
probably benign |
Het |
| Mterf4 |
T |
C |
1: 93,232,689 (GRCm39) |
E54G |
probably benign |
Het |
| Mucl3 |
A |
G |
17: 35,947,874 (GRCm39) |
S452P |
possibly damaging |
Het |
| Nuggc |
T |
A |
14: 65,882,490 (GRCm39) |
I745N |
probably damaging |
Het |
| Or6k6 |
T |
C |
1: 173,945,115 (GRCm39) |
I156V |
probably benign |
Het |
| Or7g18 |
A |
G |
9: 18,786,910 (GRCm39) |
T93A |
possibly damaging |
Het |
| Parg |
A |
T |
14: 31,930,758 (GRCm39) |
N126I |
possibly damaging |
Het |
| Pcdh9 |
T |
C |
14: 94,123,987 (GRCm39) |
I728V |
possibly damaging |
Het |
| Pcdha1 |
C |
G |
18: 37,065,511 (GRCm39) |
P725R |
probably benign |
Het |
| Pcdha11 |
T |
A |
18: 37,145,849 (GRCm39) |
L647M |
probably damaging |
Het |
| Phb2 |
T |
C |
6: 124,692,995 (GRCm39) |
|
probably null |
Het |
| Plb1 |
A |
G |
5: 32,483,610 (GRCm39) |
|
probably null |
Het |
| Pmch |
T |
A |
10: 87,927,113 (GRCm39) |
F39I |
probably benign |
Het |
| Psmd7 |
A |
T |
8: 108,307,920 (GRCm39) |
S188T |
possibly damaging |
Het |
| Pycr2 |
T |
A |
1: 180,733,913 (GRCm39) |
D168E |
probably damaging |
Het |
| Rab43 |
A |
G |
6: 87,771,692 (GRCm39) |
Y96H |
probably damaging |
Het |
| Ralgapa2 |
C |
T |
2: 146,184,334 (GRCm39) |
G1511S |
probably benign |
Het |
| Rb1cc1 |
T |
A |
1: 6,319,138 (GRCm39) |
C852* |
probably null |
Het |
| Rexo2 |
T |
C |
9: 48,380,145 (GRCm39) |
N229S |
probably damaging |
Het |
| Sema4f |
A |
G |
6: 82,890,941 (GRCm39) |
V622A |
possibly damaging |
Het |
| Serpina10 |
T |
C |
12: 103,594,806 (GRCm39) |
S138G |
probably benign |
Het |
| Sptbn4 |
T |
A |
7: 27,061,059 (GRCm39) |
T2415S |
possibly damaging |
Het |
| Tbc1d22b |
A |
G |
17: 29,792,040 (GRCm39) |
N257D |
probably benign |
Het |
| Tbl3 |
A |
G |
17: 24,921,205 (GRCm39) |
F529L |
probably damaging |
Het |
| Them6 |
A |
T |
15: 74,593,427 (GRCm39) |
N95I |
probably benign |
Het |
| Thrb |
T |
C |
14: 18,008,608 (GRCm38) |
S156P |
possibly damaging |
Het |
| Tmem186 |
G |
A |
16: 8,453,731 (GRCm39) |
R177C |
probably benign |
Het |
| Ttn |
T |
A |
2: 76,660,937 (GRCm39) |
|
probably null |
Het |
| Unc13a |
T |
A |
8: 72,110,979 (GRCm39) |
I411F |
probably benign |
Het |
| Uqcc1 |
T |
C |
2: 155,752,073 (GRCm39) |
|
probably null |
Het |
| Vmn1r56 |
T |
C |
7: 5,199,516 (GRCm39) |
T34A |
possibly damaging |
Het |
| Vps39 |
A |
T |
2: 120,155,680 (GRCm39) |
Y542* |
probably null |
Het |
| Wdr64 |
T |
C |
1: 175,556,542 (GRCm39) |
L263P |
probably damaging |
Het |
| Wfdc16 |
A |
G |
2: 164,477,785 (GRCm39) |
M88T |
probably benign |
Het |
| Wnk4 |
A |
G |
11: 101,160,403 (GRCm39) |
D679G |
probably damaging |
Het |
| Ykt6 |
T |
C |
11: 5,912,751 (GRCm39) |
I151T |
probably benign |
Het |
| Zbtb46 |
A |
G |
2: 181,033,225 (GRCm39) |
C479R |
probably damaging |
Het |
| Zc3h7a |
A |
G |
16: 10,967,115 (GRCm39) |
I559T |
probably benign |
Het |
| Zfhx3 |
A |
G |
8: 109,678,283 (GRCm39) |
N3111S |
possibly damaging |
Het |
| Zfp619 |
T |
C |
7: 39,184,432 (GRCm39) |
V154A |
possibly damaging |
Het |
| Zfp629 |
A |
T |
7: 127,211,601 (GRCm39) |
D69E |
probably benign |
Het |
| Zfp882 |
T |
A |
8: 72,668,073 (GRCm39) |
I300N |
possibly damaging |
Het |
| Zfp934 |
T |
C |
13: 62,666,358 (GRCm39) |
H106R |
possibly damaging |
Het |
| Zfta |
T |
C |
19: 7,399,737 (GRCm39) |
S495P |
probably damaging |
Het |
| Zfyve9 |
G |
A |
4: 108,576,298 (GRCm39) |
T261I |
possibly damaging |
Het |
|
| Other mutations in Wdr90 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00418:Wdr90
|
APN |
17 |
26,068,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01118:Wdr90
|
APN |
17 |
26,073,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01964:Wdr90
|
APN |
17 |
26,067,383 (GRCm39) |
missense |
probably benign |
|
|
IGL02116:Wdr90
|
APN |
17 |
26,078,466 (GRCm39) |
missense |
probably benign |
0.12 |
|
IGL02172:Wdr90
|
APN |
17 |
26,069,408 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL02716:Wdr90
|
APN |
17 |
26,076,194 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02961:Wdr90
|
APN |
17 |
26,067,649 (GRCm39) |
nonsense |
probably null |
|
|
IGL03229:Wdr90
|
APN |
17 |
26,064,437 (GRCm39) |
splice site |
probably benign |
|
|
IGL03367:Wdr90
|
APN |
17 |
26,066,765 (GRCm39) |
splice site |
probably benign |
|
|
IGL03098:Wdr90
|
UTSW |
17 |
26,078,961 (GRCm39) |
intron |
probably benign |
|
|
R0111:Wdr90
|
UTSW |
17 |
26,067,418 (GRCm39) |
splice site |
probably benign |
|
|
R0454:Wdr90
|
UTSW |
17 |
26,079,023 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0457:Wdr90
|
UTSW |
17 |
26,079,459 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0488:Wdr90
|
UTSW |
17 |
26,067,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0622:Wdr90
|
UTSW |
17 |
26,074,632 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0671:Wdr90
|
UTSW |
17 |
26,065,367 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0799:Wdr90
|
UTSW |
17 |
26,079,104 (GRCm39) |
missense |
probably benign |
0.38 |
|
R1177:Wdr90
|
UTSW |
17 |
26,065,028 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1460:Wdr90
|
UTSW |
17 |
26,079,422 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1468:Wdr90
|
UTSW |
17 |
26,073,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1468:Wdr90
|
UTSW |
17 |
26,073,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1544:Wdr90
|
UTSW |
17 |
26,068,284 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R2057:Wdr90
|
UTSW |
17 |
26,074,173 (GRCm39) |
missense |
probably benign |
0.05 |
|
R2087:Wdr90
|
UTSW |
17 |
26,065,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2159:Wdr90
|
UTSW |
17 |
26,070,715 (GRCm39) |
missense |
probably benign |
|
|
R2208:Wdr90
|
UTSW |
17 |
26,079,362 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2345:Wdr90
|
UTSW |
17 |
26,078,136 (GRCm39) |
missense |
probably benign |
0.05 |
|
R2391:Wdr90
|
UTSW |
17 |
26,070,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2394:Wdr90
|
UTSW |
17 |
26,070,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2520:Wdr90
|
UTSW |
17 |
26,074,326 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3798:Wdr90
|
UTSW |
17 |
26,069,472 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3979:Wdr90
|
UTSW |
17 |
26,078,252 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4111:Wdr90
|
UTSW |
17 |
26,068,342 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4326:Wdr90
|
UTSW |
17 |
26,072,705 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4459:Wdr90
|
UTSW |
17 |
26,079,976 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4697:Wdr90
|
UTSW |
17 |
26,074,337 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4735:Wdr90
|
UTSW |
17 |
26,078,424 (GRCm39) |
missense |
probably benign |
|
|
R4907:Wdr90
|
UTSW |
17 |
26,079,624 (GRCm39) |
intron |
probably benign |
|
|
R5070:Wdr90
|
UTSW |
17 |
26,065,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5230:Wdr90
|
UTSW |
17 |
26,074,277 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5268:Wdr90
|
UTSW |
17 |
26,069,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5287:Wdr90
|
UTSW |
17 |
26,080,441 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R5382:Wdr90
|
UTSW |
17 |
26,064,572 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5511:Wdr90
|
UTSW |
17 |
26,063,995 (GRCm39) |
unclassified |
probably benign |
|
|
R5545:Wdr90
|
UTSW |
17 |
26,064,830 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5707:Wdr90
|
UTSW |
17 |
26,076,166 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5973:Wdr90
|
UTSW |
17 |
26,065,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5973:Wdr90
|
UTSW |
17 |
26,064,107 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6385:Wdr90
|
UTSW |
17 |
26,067,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6481:Wdr90
|
UTSW |
17 |
26,064,885 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7078:Wdr90
|
UTSW |
17 |
26,068,623 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7214:Wdr90
|
UTSW |
17 |
26,064,367 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7288:Wdr90
|
UTSW |
17 |
26,065,286 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7304:Wdr90
|
UTSW |
17 |
26,070,480 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7309:Wdr90
|
UTSW |
17 |
26,079,676 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7391:Wdr90
|
UTSW |
17 |
26,065,502 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7622:Wdr90
|
UTSW |
17 |
26,073,083 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7646:Wdr90
|
UTSW |
17 |
26,079,104 (GRCm39) |
missense |
probably benign |
0.38 |
|
R7772:Wdr90
|
UTSW |
17 |
26,080,465 (GRCm39) |
start gained |
probably benign |
|
|
R7779:Wdr90
|
UTSW |
17 |
26,065,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7781:Wdr90
|
UTSW |
17 |
26,065,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7782:Wdr90
|
UTSW |
17 |
26,065,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7812:Wdr90
|
UTSW |
17 |
26,071,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7870:Wdr90
|
UTSW |
17 |
26,079,513 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7911:Wdr90
|
UTSW |
17 |
26,069,723 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8126:Wdr90
|
UTSW |
17 |
26,067,951 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8260:Wdr90
|
UTSW |
17 |
26,064,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8315:Wdr90
|
UTSW |
17 |
26,064,399 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8919:Wdr90
|
UTSW |
17 |
26,076,146 (GRCm39) |
missense |
|
|
|
R8938:Wdr90
|
UTSW |
17 |
26,076,146 (GRCm39) |
missense |
|
|
|
R8940:Wdr90
|
UTSW |
17 |
26,076,146 (GRCm39) |
missense |
|
|
|
R9038:Wdr90
|
UTSW |
17 |
26,076,200 (GRCm39) |
missense |
|
|
|
R9079:Wdr90
|
UTSW |
17 |
26,076,403 (GRCm39) |
missense |
|
|
|
R9401:Wdr90
|
UTSW |
17 |
26,064,750 (GRCm39) |
small insertion |
probably benign |
|
|
R9471:Wdr90
|
UTSW |
17 |
26,080,015 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R9642:Wdr90
|
UTSW |
17 |
26,072,694 (GRCm39) |
critical splice donor site |
probably null |
|
|
X0064:Wdr90
|
UTSW |
17 |
26,067,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Wdr90
|
UTSW |
17 |
26,079,470 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCCATTATGTGAGCCCAAC -3'
(R):5'- GGTGATCCAGTTTCAGGTGC -3'
Sequencing Primer
(F):5'- ACCCACAACCTGGAAGTGTGG -3'
(R):5'- TGCAACACTAGAGCTGTC -3'
|
| Posted On |
2019-11-26 |
Incidental Mutation