Incidental Mutation 'R4610:Nav1'
| ID |
377738 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nav1
|
| Ensembl Gene |
ENSMUSG00000009418 |
| Gene Name |
neuron navigator 1 |
| Synonyms |
steerin-1, C230080M11Rik, unc53H1, 9930003A20Rik, POMFIL3 |
| MMRRC Submission |
041821-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.933)
|
| Stock # |
R4610 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
135434580-135607295 bp(-) (GRCm38) |
| Type of Mutation |
intron |
| DNA Base Change (assembly) |
A to G
at 135592448 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000140322
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000190298]
|
| AlphaFold |
Q8CH77 |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000067468
|
| SMART Domains |
Protein: ENSMUSP00000067952
Gene: ENSMUSG00000054412
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
118 |
146 |
N/A |
INTRINSIC |
|
transmembrane domain
|
164 |
181 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000190298
|
| SMART Domains |
Protein: ENSMUSP00000140322
Gene: ENSMUSG00000009418
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
33 |
N/A |
INTRINSIC |
|
low complexity region
|
48 |
65 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
303 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
414 |
428 |
N/A |
INTRINSIC |
|
low complexity region
|
436 |
456 |
N/A |
INTRINSIC |
|
low complexity region
|
739 |
749 |
N/A |
INTRINSIC |
|
low complexity region
|
807 |
818 |
N/A |
INTRINSIC |
|
low complexity region
|
892 |
913 |
N/A |
INTRINSIC |
|
low complexity region
|
975 |
989 |
N/A |
INTRINSIC |
|
coiled coil region
|
1013 |
1048 |
N/A |
INTRINSIC |
|
low complexity region
|
1122 |
1153 |
N/A |
INTRINSIC |
|
low complexity region
|
1200 |
1221 |
N/A |
INTRINSIC |
|
low complexity region
|
1236 |
1244 |
N/A |
INTRINSIC |
|
coiled coil region
|
1268 |
1300 |
N/A |
INTRINSIC |
|
AAA
|
1488 |
1642 |
3.16e-5 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.5%
|
| Validation Efficiency |
98% (121/124) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 117 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aars2 |
T |
A |
17: 45,516,921 (GRCm38) |
D555E |
probably damaging |
Het |
| Adgre1 |
C |
A |
17: 57,450,073 (GRCm38) |
Q777K |
possibly damaging |
Het |
| Agpat4 |
G |
A |
17: 12,210,377 (GRCm38) |
|
probably null |
Het |
| Ak7 |
G |
A |
12: 105,713,575 (GRCm38) |
V123M |
probably benign |
Het |
| Ankle1 |
AT |
A |
8: 71,407,207 (GRCm38) |
|
probably benign |
Het |
| Ankrd44 |
T |
G |
1: 54,766,748 (GRCm38) |
|
probably benign |
Het |
| Aprt |
A |
T |
8: 122,575,415 (GRCm38) |
|
probably null |
Het |
| Aptx |
T |
C |
4: 40,702,766 (GRCm38) |
|
probably null |
Het |
| Arsi |
G |
A |
18: 60,916,651 (GRCm38) |
G202E |
probably benign |
Het |
| AY358078 |
T |
A |
14: 51,826,075 (GRCm38) |
C393S |
possibly damaging |
Het |
| Bbip1 |
T |
C |
19: 53,932,175 (GRCm38) |
M1V |
probably null |
Het |
| Cacng7 |
T |
A |
7: 3,336,691 (GRCm38) |
M36K |
probably benign |
Het |
| Camta1 |
A |
G |
4: 151,084,827 (GRCm38) |
W156R |
probably damaging |
Het |
| Casd1 |
G |
A |
6: 4,631,165 (GRCm38) |
|
probably null |
Het |
| Casz1 |
T |
A |
4: 148,933,267 (GRCm38) |
Y338N |
probably damaging |
Het |
| Ccdc66 |
T |
C |
14: 27,500,420 (GRCm38) |
N122S |
probably damaging |
Het |
| Celf2 |
G |
T |
2: 6,586,020 (GRCm38) |
N279K |
possibly damaging |
Het |
| Cfap96 |
A |
T |
8: 45,970,468 (GRCm38) |
I69N |
probably damaging |
Het |
| Cit |
A |
G |
5: 115,994,087 (GRCm38) |
T1801A |
probably benign |
Het |
| Cnot2 |
A |
G |
10: 116,499,418 (GRCm38) |
I275T |
probably damaging |
Het |
| Ddx4 |
T |
C |
13: 112,612,060 (GRCm38) |
K435E |
probably damaging |
Het |
| Dnajc6 |
T |
C |
4: 101,611,264 (GRCm38) |
F166L |
probably damaging |
Het |
| Dst |
T |
C |
1: 34,169,856 (GRCm38) |
L820P |
probably damaging |
Het |
| Dusp11 |
T |
A |
6: 85,950,055 (GRCm38) |
N193Y |
probably damaging |
Het |
| Eif1ad7 |
T |
C |
12: 88,271,774 (GRCm38) |
N72S |
probably benign |
Het |
| Eif3m |
A |
T |
2: 105,013,288 (GRCm38) |
N116K |
probably benign |
Het |
| Epb41l1 |
A |
T |
2: 156,509,261 (GRCm38) |
E418D |
possibly damaging |
Het |
| Esyt2 |
T |
G |
12: 116,318,890 (GRCm38) |
N153K |
probably damaging |
Het |
| Exoc6b |
T |
G |
6: 85,003,159 (GRCm38) |
|
probably benign |
Het |
| Ezr |
C |
T |
17: 6,739,722 (GRCm38) |
E502K |
possibly damaging |
Het |
| Fbxw11 |
T |
A |
11: 32,711,859 (GRCm38) |
Y66N |
possibly damaging |
Het |
| Frem2 |
A |
G |
3: 53,547,807 (GRCm38) |
L2116S |
possibly damaging |
Het |
| Fry |
T |
C |
5: 150,386,104 (GRCm38) |
L671P |
probably damaging |
Het |
| Galnt7 |
A |
G |
8: 57,545,769 (GRCm38) |
I262T |
probably damaging |
Het |
| Glp1r |
T |
C |
17: 30,931,247 (GRCm38) |
F381S |
probably benign |
Het |
| Gm3867 |
T |
C |
9: 36,257,271 (GRCm38) |
|
noncoding transcript |
Het |
| Gm8741 |
G |
T |
17: 35,336,086 (GRCm38) |
|
noncoding transcript |
Het |
| Golgb1 |
A |
G |
16: 36,918,625 (GRCm38) |
D2442G |
probably damaging |
Het |
| Gp1bb |
A |
T |
16: 18,621,143 (GRCm38) |
L67Q |
probably damaging |
Het |
| Gstm7 |
G |
A |
3: 107,926,919 (GRCm38) |
T206I |
possibly damaging |
Het |
| H2bc7 |
A |
T |
13: 23,574,057 (GRCm38) |
V45E |
possibly damaging |
Het |
| Hs3st5 |
A |
T |
10: 36,828,806 (GRCm38) |
D35V |
probably benign |
Het |
| Hspa13 |
T |
C |
16: 75,761,302 (GRCm38) |
H125R |
probably benign |
Het |
| Hspa1a |
T |
G |
17: 34,971,180 (GRCm38) |
H249P |
probably damaging |
Het |
| Igkv10-95 |
A |
T |
6: 68,680,578 (GRCm38) |
Q6L |
probably damaging |
Het |
| Il1rap |
T |
A |
16: 26,714,776 (GRCm38) |
L474H |
probably benign |
Het |
| Ipo11 |
T |
A |
13: 106,879,737 (GRCm38) |
Y489F |
probably benign |
Het |
| Itga5 |
A |
G |
15: 103,350,832 (GRCm38) |
Y723H |
probably damaging |
Het |
| Itih2 |
T |
C |
2: 10,105,160 (GRCm38) |
N594S |
probably damaging |
Het |
| Itk |
T |
A |
11: 46,336,515 (GRCm38) |
Q427L |
probably benign |
Het |
| Kif26b |
A |
G |
1: 178,679,355 (GRCm38) |
Y332C |
probably damaging |
Het |
| Kmt2c |
G |
A |
5: 25,354,384 (GRCm38) |
R1086W |
probably damaging |
Het |
| Ktn1 |
T |
A |
14: 47,726,179 (GRCm38) |
|
probably benign |
Het |
| Lars2 |
T |
A |
9: 123,418,693 (GRCm38) |
I305N |
probably damaging |
Het |
| Lgmn |
G |
T |
12: 102,400,124 (GRCm38) |
|
probably benign |
Het |
| Ltbp4 |
C |
T |
7: 27,306,700 (GRCm38) |
E1453K |
probably damaging |
Het |
| Lypd8 |
G |
A |
11: 58,386,849 (GRCm38) |
M152I |
probably benign |
Het |
| Man2a1 |
T |
A |
17: 64,712,459 (GRCm38) |
S773T |
probably benign |
Het |
| Map2k6 |
T |
G |
11: 110,499,474 (GRCm38) |
L278R |
probably damaging |
Het |
| Mbtps1 |
A |
T |
8: 119,535,347 (GRCm38) |
D354E |
probably damaging |
Het |
| Mcpt9 |
C |
T |
14: 56,028,592 (GRCm38) |
V60M |
probably damaging |
Het |
| Mical3 |
C |
A |
6: 120,934,838 (GRCm38) |
E1083* |
probably null |
Het |
| Mms19 |
A |
G |
19: 41,945,496 (GRCm38) |
V811A |
possibly damaging |
Het |
| Mrc2 |
G |
A |
11: 105,348,431 (GRCm38) |
|
probably null |
Het |
| Mslnl |
G |
A |
17: 25,742,934 (GRCm38) |
V128M |
probably damaging |
Het |
| Mtcl1 |
T |
A |
17: 66,377,887 (GRCm38) |
H520L |
probably benign |
Het |
| Mymk |
A |
T |
2: 27,062,707 (GRCm38) |
F130I |
probably damaging |
Het |
| Myo1f |
C |
T |
17: 33,582,332 (GRCm38) |
R333C |
probably damaging |
Het |
| Myo9a |
T |
A |
9: 59,871,882 (GRCm38) |
H1640Q |
probably benign |
Het |
| Ncbp3 |
G |
T |
11: 73,079,018 (GRCm38) |
G564C |
probably damaging |
Het |
| Ncoa4 |
A |
T |
14: 32,176,725 (GRCm38) |
I501L |
probably benign |
Het |
| Ngp |
T |
A |
9: 110,420,815 (GRCm38) |
N60K |
possibly damaging |
Het |
| Npc1l1 |
G |
T |
11: 6,228,215 (GRCm38) |
D398E |
probably damaging |
Het |
| Nphs2 |
T |
A |
1: 156,326,131 (GRCm38) |
M264K |
probably damaging |
Het |
| Or4s2b |
T |
G |
2: 88,678,179 (GRCm38) |
V101G |
probably benign |
Het |
| Or4s2b |
G |
A |
2: 88,677,896 (GRCm38) |
V14I |
probably benign |
Het |
| Or7e165 |
T |
A |
9: 19,783,146 (GRCm38) |
Y4* |
probably null |
Het |
| Or8b8 |
T |
A |
9: 37,898,326 (GRCm38) |
S307R |
probably benign |
Het |
| Patz1 |
A |
G |
11: 3,306,241 (GRCm38) |
Y509C |
probably damaging |
Het |
| Pax8 |
G |
A |
2: 24,421,583 (GRCm38) |
P447S |
probably damaging |
Het |
| Pde11a |
A |
G |
2: 76,158,333 (GRCm38) |
V488A |
probably benign |
Het |
| Pex11g |
C |
T |
8: 3,465,899 (GRCm38) |
V45M |
probably benign |
Het |
| Pik3ip1 |
T |
A |
11: 3,333,327 (GRCm38) |
S142R |
probably damaging |
Het |
| Pitpnm2 |
C |
G |
5: 124,125,371 (GRCm38) |
A819P |
probably damaging |
Het |
| Pla2g4e |
T |
G |
2: 120,186,382 (GRCm38) |
H226P |
possibly damaging |
Het |
| Plin4 |
T |
A |
17: 56,105,418 (GRCm38) |
M538L |
probably benign |
Het |
| Ppp3cb |
T |
C |
14: 20,520,646 (GRCm38) |
N339S |
possibly damaging |
Het |
| Rev1 |
T |
C |
1: 38,053,649 (GRCm38) |
E1202G |
probably damaging |
Het |
| Rngtt |
T |
A |
4: 33,339,133 (GRCm38) |
|
probably benign |
Het |
| Serpinb12 |
T |
A |
1: 106,949,153 (GRCm38) |
D66E |
probably benign |
Het |
| Sgsm1 |
A |
T |
5: 113,255,307 (GRCm38) |
F958Y |
probably damaging |
Het |
| Slc35e2 |
T |
C |
4: 155,617,649 (GRCm38) |
F290S |
probably benign |
Het |
| Sorl1 |
C |
T |
9: 42,031,914 (GRCm38) |
V889M |
possibly damaging |
Het |
| Sptlc3 |
G |
A |
2: 139,636,680 (GRCm38) |
V520I |
probably benign |
Het |
| Stam |
A |
T |
2: 14,115,858 (GRCm38) |
H53L |
probably damaging |
Het |
| Stox2 |
A |
G |
8: 47,192,935 (GRCm38) |
S497P |
probably damaging |
Het |
| Tarbp1 |
A |
G |
8: 126,474,330 (GRCm38) |
Y246H |
probably damaging |
Het |
| Tbx15 |
A |
G |
3: 99,352,367 (GRCm38) |
Y518C |
probably damaging |
Het |
| Tdrd5 |
T |
A |
1: 156,284,374 (GRCm38) |
T479S |
probably benign |
Het |
| Tescl |
T |
C |
7: 24,333,258 (GRCm38) |
E214G |
probably damaging |
Het |
| Tex10 |
T |
C |
4: 48,452,946 (GRCm38) |
D671G |
probably benign |
Het |
| Tmem132d |
A |
G |
5: 127,984,296 (GRCm38) |
V414A |
probably benign |
Het |
| Tmem41b |
T |
A |
7: 109,974,734 (GRCm38) |
|
probably benign |
Het |
| Tnfrsf18 |
A |
G |
4: 156,021,880 (GRCm38) |
|
probably benign |
Het |
| Tulp4 |
T |
A |
17: 6,198,833 (GRCm38) |
D42E |
probably damaging |
Het |
| Ubtd1 |
A |
G |
19: 42,033,664 (GRCm38) |
N125S |
probably damaging |
Het |
| Ubxn4 |
T |
A |
1: 128,255,449 (GRCm38) |
F68I |
probably benign |
Het |
| Urb1 |
A |
G |
16: 90,776,271 (GRCm38) |
S958P |
probably benign |
Het |
| Vash2 |
T |
C |
1: 190,960,301 (GRCm38) |
S226G |
probably benign |
Het |
| Vmn2r120 |
C |
T |
17: 57,509,120 (GRCm38) |
G745E |
probably damaging |
Het |
| Vmn2r58 |
T |
A |
7: 41,837,693 (GRCm38) |
I593F |
probably benign |
Het |
| Zfp398 |
T |
C |
6: 47,840,427 (GRCm38) |
L67P |
probably damaging |
Het |
| Zfp607b |
T |
A |
7: 27,703,695 (GRCm38) |
H525Q |
probably damaging |
Het |
| Zfp629 |
T |
C |
7: 127,612,320 (GRCm38) |
T106A |
probably benign |
Het |
| Zfp980 |
G |
A |
4: 145,702,083 (GRCm38) |
G461S |
probably benign |
Het |
| Zic5 |
T |
A |
14: 122,464,800 (GRCm38) |
D173V |
probably damaging |
Het |
| Zranb2 |
G |
A |
3: 157,541,884 (GRCm38) |
|
probably benign |
Het |
|
| Other mutations in Nav1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01061:Nav1
|
APN |
1 |
135,450,630 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01455:Nav1
|
APN |
1 |
135,469,635 (GRCm38) |
missense |
probably benign |
0.44 |
|
IGL01650:Nav1
|
APN |
1 |
135,454,760 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01872:Nav1
|
APN |
1 |
135,454,076 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01967:Nav1
|
APN |
1 |
135,537,245 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02167:Nav1
|
APN |
1 |
135,470,961 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02278:Nav1
|
APN |
1 |
135,463,714 (GRCm38) |
splice site |
probably benign |
|
|
IGL02343:Nav1
|
APN |
1 |
135,454,752 (GRCm38) |
nonsense |
probably null |
|
|
IGL02378:Nav1
|
APN |
1 |
135,469,978 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL02554:Nav1
|
APN |
1 |
135,584,913 (GRCm38) |
synonymous |
silent |
|
|
IGL03148:Nav1
|
APN |
1 |
135,470,024 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL03286:Nav1
|
APN |
1 |
135,454,536 (GRCm38) |
missense |
probably benign |
|
|
IGL03372:Nav1
|
APN |
1 |
135,450,903 (GRCm38) |
missense |
probably damaging |
0.99 |
|
PIT4802001:Nav1
|
UTSW |
1 |
135,452,933 (GRCm38) |
missense |
unknown |
|
|
R0388:Nav1
|
UTSW |
1 |
135,448,917 (GRCm38) |
splice site |
probably benign |
|
|
R0390:Nav1
|
UTSW |
1 |
135,449,966 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R0395:Nav1
|
UTSW |
1 |
135,532,623 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R0395:Nav1
|
UTSW |
1 |
135,532,621 (GRCm38) |
nonsense |
probably null |
|
|
R0416:Nav1
|
UTSW |
1 |
135,471,126 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R0463:Nav1
|
UTSW |
1 |
135,452,207 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
R0538:Nav1
|
UTSW |
1 |
135,464,692 (GRCm38) |
splice site |
probably benign |
|
|
R0594:Nav1
|
UTSW |
1 |
135,467,643 (GRCm38) |
missense |
possibly damaging |
0.74 |
|
R0696:Nav1
|
UTSW |
1 |
135,532,614 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0699:Nav1
|
UTSW |
1 |
135,452,949 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0759:Nav1
|
UTSW |
1 |
135,455,260 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R1164:Nav1
|
UTSW |
1 |
135,472,410 (GRCm38) |
missense |
probably benign |
|
|
R1169:Nav1
|
UTSW |
1 |
135,455,205 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1401:Nav1
|
UTSW |
1 |
135,460,425 (GRCm38) |
missense |
probably benign |
0.20 |
|
R1421:Nav1
|
UTSW |
1 |
135,585,010 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1642:Nav1
|
UTSW |
1 |
135,452,272 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1705:Nav1
|
UTSW |
1 |
135,584,599 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1713:Nav1
|
UTSW |
1 |
135,595,234 (GRCm38) |
intron |
probably benign |
|
|
R1728:Nav1
|
UTSW |
1 |
135,584,727 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R1729:Nav1
|
UTSW |
1 |
135,584,727 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R1730:Nav1
|
UTSW |
1 |
135,584,727 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R1739:Nav1
|
UTSW |
1 |
135,584,727 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R1740:Nav1
|
UTSW |
1 |
135,458,389 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1762:Nav1
|
UTSW |
1 |
135,584,727 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R1783:Nav1
|
UTSW |
1 |
135,584,727 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R1784:Nav1
|
UTSW |
1 |
135,584,727 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R1785:Nav1
|
UTSW |
1 |
135,584,727 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R1895:Nav1
|
UTSW |
1 |
135,458,658 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1896:Nav1
|
UTSW |
1 |
135,460,737 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1901:Nav1
|
UTSW |
1 |
135,472,410 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1902:Nav1
|
UTSW |
1 |
135,472,410 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1925:Nav1
|
UTSW |
1 |
135,607,229 (GRCm38) |
utr 5 prime |
probably benign |
|
|
R1939:Nav1
|
UTSW |
1 |
135,465,898 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1971:Nav1
|
UTSW |
1 |
135,532,353 (GRCm38) |
missense |
probably benign |
0.06 |
|
R2063:Nav1
|
UTSW |
1 |
135,449,004 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2066:Nav1
|
UTSW |
1 |
135,449,004 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2084:Nav1
|
UTSW |
1 |
135,607,420 (GRCm38) |
unclassified |
probably benign |
|
|
R2090:Nav1
|
UTSW |
1 |
135,607,165 (GRCm38) |
utr 5 prime |
probably benign |
|
|
R2107:Nav1
|
UTSW |
1 |
135,449,004 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2110:Nav1
|
UTSW |
1 |
135,449,004 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2111:Nav1
|
UTSW |
1 |
135,449,004 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2112:Nav1
|
UTSW |
1 |
135,449,004 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2136:Nav1
|
UTSW |
1 |
135,454,436 (GRCm38) |
missense |
probably null |
0.18 |
|
R2268:Nav1
|
UTSW |
1 |
135,472,236 (GRCm38) |
nonsense |
probably null |
|
|
R2269:Nav1
|
UTSW |
1 |
135,472,236 (GRCm38) |
nonsense |
probably null |
|
|
R2847:Nav1
|
UTSW |
1 |
135,450,644 (GRCm38) |
splice site |
probably null |
|
|
R2869:Nav1
|
UTSW |
1 |
135,460,757 (GRCm38) |
synonymous |
silent |
|
|
R2871:Nav1
|
UTSW |
1 |
135,460,757 (GRCm38) |
synonymous |
silent |
|
|
R2872:Nav1
|
UTSW |
1 |
135,460,757 (GRCm38) |
synonymous |
silent |
|
|
R2904:Nav1
|
UTSW |
1 |
135,585,238 (GRCm38) |
missense |
probably benign |
|
|
R3690:Nav1
|
UTSW |
1 |
135,467,644 (GRCm38) |
missense |
probably benign |
0.11 |
|
R3716:Nav1
|
UTSW |
1 |
135,450,630 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3717:Nav1
|
UTSW |
1 |
135,450,630 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3718:Nav1
|
UTSW |
1 |
135,450,630 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3815:Nav1
|
UTSW |
1 |
135,471,124 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R4282:Nav1
|
UTSW |
1 |
135,457,913 (GRCm38) |
intron |
probably benign |
|
|
R4361:Nav1
|
UTSW |
1 |
135,607,437 (GRCm38) |
unclassified |
probably benign |
|
|
R4730:Nav1
|
UTSW |
1 |
135,607,311 (GRCm38) |
unclassified |
probably benign |
|
|
R4784:Nav1
|
UTSW |
1 |
135,458,739 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4788:Nav1
|
UTSW |
1 |
135,469,723 (GRCm38) |
missense |
probably benign |
|
|
R4808:Nav1
|
UTSW |
1 |
135,455,204 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4996:Nav1
|
UTSW |
1 |
135,465,971 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5284:Nav1
|
UTSW |
1 |
135,449,963 (GRCm38) |
nonsense |
probably null |
|
|
R5514:Nav1
|
UTSW |
1 |
135,470,561 (GRCm38) |
missense |
probably benign |
0.04 |
|
R5769:Nav1
|
UTSW |
1 |
135,452,257 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5834:Nav1
|
UTSW |
1 |
135,532,406 (GRCm38) |
missense |
probably benign |
0.07 |
|
R5898:Nav1
|
UTSW |
1 |
135,585,146 (GRCm38) |
missense |
probably benign |
|
|
R6081:Nav1
|
UTSW |
1 |
135,470,822 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6344:Nav1
|
UTSW |
1 |
135,450,796 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6378:Nav1
|
UTSW |
1 |
135,454,695 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7001:Nav1
|
UTSW |
1 |
135,454,611 (GRCm38) |
splice site |
probably null |
|
|
R7185:Nav1
|
UTSW |
1 |
135,471,008 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R7291:Nav1
|
UTSW |
1 |
135,465,859 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7361:Nav1
|
UTSW |
1 |
135,452,853 (GRCm38) |
missense |
unknown |
|
|
R7390:Nav1
|
UTSW |
1 |
135,584,918 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7464:Nav1
|
UTSW |
1 |
135,584,909 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7502:Nav1
|
UTSW |
1 |
135,469,666 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7601:Nav1
|
UTSW |
1 |
135,460,438 (GRCm38) |
missense |
unknown |
|
|
R7625:Nav1
|
UTSW |
1 |
135,467,745 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7639:Nav1
|
UTSW |
1 |
135,471,122 (GRCm38) |
missense |
probably benign |
0.09 |
|
R7786:Nav1
|
UTSW |
1 |
135,469,995 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7808:Nav1
|
UTSW |
1 |
135,452,248 (GRCm38) |
missense |
unknown |
|
|
R7815:Nav1
|
UTSW |
1 |
135,584,639 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R7825:Nav1
|
UTSW |
1 |
135,450,044 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8030:Nav1
|
UTSW |
1 |
135,537,239 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8370:Nav1
|
UTSW |
1 |
135,471,144 (GRCm38) |
nonsense |
probably null |
|
|
R8405:Nav1
|
UTSW |
1 |
135,454,770 (GRCm38) |
missense |
unknown |
|
|
R8720:Nav1
|
UTSW |
1 |
135,460,726 (GRCm38) |
missense |
unknown |
|
|
R8868:Nav1
|
UTSW |
1 |
135,585,205 (GRCm38) |
missense |
probably benign |
0.05 |
|
R8973:Nav1
|
UTSW |
1 |
135,584,725 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9039:Nav1
|
UTSW |
1 |
135,443,749 (GRCm38) |
missense |
unknown |
|
|
R9261:Nav1
|
UTSW |
1 |
135,460,357 (GRCm38) |
missense |
unknown |
|
|
R9523:Nav1
|
UTSW |
1 |
135,452,191 (GRCm38) |
missense |
unknown |
|
|
Z1088:Nav1
|
UTSW |
1 |
135,470,724 (GRCm38) |
missense |
probably benign |
0.01 |
|
Z1176:Nav1
|
UTSW |
1 |
135,472,420 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Nav1
|
UTSW |
1 |
135,452,886 (GRCm38) |
missense |
unknown |
|
|
Z1177:Nav1
|
UTSW |
1 |
135,469,731 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTATGACAAGTGTTCTGGACCC -3'
(R):5'- AGCATTAGGGGCCATGGTTG -3'
Sequencing Primer
(F):5'- GAGTACACTGTAGCTGTCTTCAGAC -3'
(R):5'- CCATGGTTGCCAGGAGATG -3'
|
| Posted On |
2016-04-01 |
Incidental Mutation