Incidental Mutation 'R4610:Nav1'
| ID |
377738 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nav1
|
| Ensembl Gene |
ENSMUSG00000009418 |
| Gene Name |
neuron navigator 1 |
| Synonyms |
9930003A20Rik, unc53H1, steerin-1, POMFIL3, C230080M11Rik |
| MMRRC Submission |
041821-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.934)
|
| Stock # |
R4610 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
135362318-135615843 bp(-) (GRCm39) |
| Type of Mutation |
intron |
| DNA Base Change (assembly) |
A to G
at 135520186 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000140322
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000190298]
|
| AlphaFold |
Q8CH77 |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000067468
|
| SMART Domains |
Protein: ENSMUSP00000067952
Gene: ENSMUSG00000054412
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
118 |
146 |
N/A |
INTRINSIC |
|
transmembrane domain
|
164 |
181 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000190298
|
| SMART Domains |
Protein: ENSMUSP00000140322
Gene: ENSMUSG00000009418
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
33 |
N/A |
INTRINSIC |
|
low complexity region
|
48 |
65 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
303 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
414 |
428 |
N/A |
INTRINSIC |
|
low complexity region
|
436 |
456 |
N/A |
INTRINSIC |
|
low complexity region
|
739 |
749 |
N/A |
INTRINSIC |
|
low complexity region
|
807 |
818 |
N/A |
INTRINSIC |
|
low complexity region
|
892 |
913 |
N/A |
INTRINSIC |
|
low complexity region
|
975 |
989 |
N/A |
INTRINSIC |
|
coiled coil region
|
1013 |
1048 |
N/A |
INTRINSIC |
|
low complexity region
|
1122 |
1153 |
N/A |
INTRINSIC |
|
low complexity region
|
1200 |
1221 |
N/A |
INTRINSIC |
|
low complexity region
|
1236 |
1244 |
N/A |
INTRINSIC |
|
coiled coil region
|
1268 |
1300 |
N/A |
INTRINSIC |
|
AAA
|
1488 |
1642 |
3.16e-5 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.5%
|
| Validation Efficiency |
98% (121/124) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 117 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aars2 |
T |
A |
17: 45,827,847 (GRCm39) |
D555E |
probably damaging |
Het |
| Adgre1 |
C |
A |
17: 57,757,073 (GRCm39) |
Q777K |
possibly damaging |
Het |
| Agpat4 |
G |
A |
17: 12,429,264 (GRCm39) |
|
probably null |
Het |
| Ak7 |
G |
A |
12: 105,679,834 (GRCm39) |
V123M |
probably benign |
Het |
| Ankle1 |
AT |
A |
8: 71,859,851 (GRCm39) |
|
probably benign |
Het |
| Ankrd44 |
T |
G |
1: 54,805,907 (GRCm39) |
|
probably benign |
Het |
| Aprt |
A |
T |
8: 123,302,154 (GRCm39) |
|
probably null |
Het |
| Aptx |
T |
C |
4: 40,702,766 (GRCm39) |
|
probably null |
Het |
| Arsi |
G |
A |
18: 61,049,723 (GRCm39) |
G202E |
probably benign |
Het |
| AY358078 |
T |
A |
14: 52,063,532 (GRCm39) |
C393S |
possibly damaging |
Het |
| Bbip1 |
T |
C |
19: 53,920,606 (GRCm39) |
M1V |
probably null |
Het |
| Cacng7 |
T |
A |
7: 3,385,207 (GRCm39) |
M36K |
probably benign |
Het |
| Camta1 |
A |
G |
4: 151,169,284 (GRCm39) |
W156R |
probably damaging |
Het |
| Casd1 |
G |
A |
6: 4,631,165 (GRCm39) |
|
probably null |
Het |
| Casz1 |
T |
A |
4: 149,017,724 (GRCm39) |
Y338N |
probably damaging |
Het |
| Ccdc66 |
T |
C |
14: 27,222,377 (GRCm39) |
N122S |
probably damaging |
Het |
| Celf2 |
G |
T |
2: 6,590,831 (GRCm39) |
N279K |
possibly damaging |
Het |
| Cfap96 |
A |
T |
8: 46,423,505 (GRCm39) |
I69N |
probably damaging |
Het |
| Cit |
A |
G |
5: 116,132,146 (GRCm39) |
T1801A |
probably benign |
Het |
| Cnot2 |
A |
G |
10: 116,335,323 (GRCm39) |
I275T |
probably damaging |
Het |
| Ddx4 |
T |
C |
13: 112,748,594 (GRCm39) |
K435E |
probably damaging |
Het |
| Dnajc6 |
T |
C |
4: 101,468,461 (GRCm39) |
F166L |
probably damaging |
Het |
| Dst |
T |
C |
1: 34,208,937 (GRCm39) |
L820P |
probably damaging |
Het |
| Dusp11 |
T |
A |
6: 85,927,037 (GRCm39) |
N193Y |
probably damaging |
Het |
| Eif1ad7 |
T |
C |
12: 88,238,544 (GRCm39) |
N72S |
probably benign |
Het |
| Eif3m |
A |
T |
2: 104,843,633 (GRCm39) |
N116K |
probably benign |
Het |
| Epb41l1 |
A |
T |
2: 156,351,181 (GRCm39) |
E418D |
possibly damaging |
Het |
| Esyt2 |
T |
G |
12: 116,282,510 (GRCm39) |
N153K |
probably damaging |
Het |
| Exoc6b |
T |
G |
6: 84,980,141 (GRCm39) |
|
probably benign |
Het |
| Ezr |
C |
T |
17: 7,007,121 (GRCm39) |
E502K |
possibly damaging |
Het |
| Fbxw11 |
T |
A |
11: 32,661,859 (GRCm39) |
Y66N |
possibly damaging |
Het |
| Frem2 |
A |
G |
3: 53,455,228 (GRCm39) |
L2116S |
possibly damaging |
Het |
| Fry |
T |
C |
5: 150,309,569 (GRCm39) |
L671P |
probably damaging |
Het |
| Galnt7 |
A |
G |
8: 57,998,803 (GRCm39) |
I262T |
probably damaging |
Het |
| Glp1r |
T |
C |
17: 31,150,221 (GRCm39) |
F381S |
probably benign |
Het |
| Gm3867 |
T |
C |
9: 36,168,567 (GRCm39) |
|
noncoding transcript |
Het |
| Gm8741 |
G |
T |
17: 35,555,062 (GRCm39) |
|
noncoding transcript |
Het |
| Golgb1 |
A |
G |
16: 36,738,987 (GRCm39) |
D2442G |
probably damaging |
Het |
| Gp1bb |
A |
T |
16: 18,439,893 (GRCm39) |
L67Q |
probably damaging |
Het |
| Gstm7 |
G |
A |
3: 107,834,235 (GRCm39) |
T206I |
possibly damaging |
Het |
| H2bc7 |
A |
T |
13: 23,758,231 (GRCm39) |
V45E |
possibly damaging |
Het |
| Hs3st5 |
A |
T |
10: 36,704,802 (GRCm39) |
D35V |
probably benign |
Het |
| Hspa13 |
T |
C |
16: 75,558,190 (GRCm39) |
H125R |
probably benign |
Het |
| Hspa1a |
T |
G |
17: 35,190,156 (GRCm39) |
H249P |
probably damaging |
Het |
| Igkv10-95 |
A |
T |
6: 68,657,562 (GRCm39) |
Q6L |
probably damaging |
Het |
| Il1rap |
T |
A |
16: 26,533,526 (GRCm39) |
L474H |
probably benign |
Het |
| Ipo11 |
T |
A |
13: 107,016,245 (GRCm39) |
Y489F |
probably benign |
Het |
| Itga5 |
A |
G |
15: 103,259,259 (GRCm39) |
Y723H |
probably damaging |
Het |
| Itih2 |
T |
C |
2: 10,109,971 (GRCm39) |
N594S |
probably damaging |
Het |
| Itk |
T |
A |
11: 46,227,342 (GRCm39) |
Q427L |
probably benign |
Het |
| Kif26b |
A |
G |
1: 178,506,920 (GRCm39) |
Y332C |
probably damaging |
Het |
| Kmt2c |
G |
A |
5: 25,559,382 (GRCm39) |
R1086W |
probably damaging |
Het |
| Ktn1 |
T |
A |
14: 47,963,636 (GRCm39) |
|
probably benign |
Het |
| Lars2 |
T |
A |
9: 123,247,758 (GRCm39) |
I305N |
probably damaging |
Het |
| Lgmn |
G |
T |
12: 102,366,383 (GRCm39) |
|
probably benign |
Het |
| Ltbp4 |
C |
T |
7: 27,006,125 (GRCm39) |
E1453K |
probably damaging |
Het |
| Lypd8 |
G |
A |
11: 58,277,675 (GRCm39) |
M152I |
probably benign |
Het |
| Man2a1 |
T |
A |
17: 65,019,454 (GRCm39) |
S773T |
probably benign |
Het |
| Map2k6 |
T |
G |
11: 110,390,300 (GRCm39) |
L278R |
probably damaging |
Het |
| Mbtps1 |
A |
T |
8: 120,262,086 (GRCm39) |
D354E |
probably damaging |
Het |
| Mcpt9 |
C |
T |
14: 56,266,049 (GRCm39) |
V60M |
probably damaging |
Het |
| Mical3 |
C |
A |
6: 120,911,799 (GRCm39) |
E1083* |
probably null |
Het |
| Mms19 |
A |
G |
19: 41,933,935 (GRCm39) |
V811A |
possibly damaging |
Het |
| Mrc2 |
G |
A |
11: 105,239,257 (GRCm39) |
|
probably null |
Het |
| Mslnl |
G |
A |
17: 25,961,908 (GRCm39) |
V128M |
probably damaging |
Het |
| Mtcl1 |
T |
A |
17: 66,684,882 (GRCm39) |
H520L |
probably benign |
Het |
| Mymk |
A |
T |
2: 26,952,719 (GRCm39) |
F130I |
probably damaging |
Het |
| Myo1f |
C |
T |
17: 33,801,306 (GRCm39) |
R333C |
probably damaging |
Het |
| Myo9a |
T |
A |
9: 59,779,165 (GRCm39) |
H1640Q |
probably benign |
Het |
| Ncbp3 |
G |
T |
11: 72,969,844 (GRCm39) |
G564C |
probably damaging |
Het |
| Ncoa4 |
A |
T |
14: 31,898,682 (GRCm39) |
I501L |
probably benign |
Het |
| Ngp |
T |
A |
9: 110,249,883 (GRCm39) |
N60K |
possibly damaging |
Het |
| Npc1l1 |
G |
T |
11: 6,178,215 (GRCm39) |
D398E |
probably damaging |
Het |
| Nphs2 |
T |
A |
1: 156,153,701 (GRCm39) |
M264K |
probably damaging |
Het |
| Or4s2b |
G |
A |
2: 88,508,240 (GRCm39) |
V14I |
probably benign |
Het |
| Or4s2b |
T |
G |
2: 88,508,523 (GRCm39) |
V101G |
probably benign |
Het |
| Or7e165 |
T |
A |
9: 19,694,442 (GRCm39) |
Y4* |
probably null |
Het |
| Or8b8 |
T |
A |
9: 37,809,622 (GRCm39) |
S307R |
probably benign |
Het |
| Patz1 |
A |
G |
11: 3,256,241 (GRCm39) |
Y509C |
probably damaging |
Het |
| Pax8 |
G |
A |
2: 24,311,595 (GRCm39) |
P447S |
probably damaging |
Het |
| Pde11a |
A |
G |
2: 75,988,677 (GRCm39) |
V488A |
probably benign |
Het |
| Pex11g |
C |
T |
8: 3,515,899 (GRCm39) |
V45M |
probably benign |
Het |
| Pik3ip1 |
T |
A |
11: 3,283,327 (GRCm39) |
S142R |
probably damaging |
Het |
| Pitpnm2 |
C |
G |
5: 124,263,434 (GRCm39) |
A819P |
probably damaging |
Het |
| Pla2g4e |
T |
G |
2: 120,016,863 (GRCm39) |
H226P |
possibly damaging |
Het |
| Plin4 |
T |
A |
17: 56,412,418 (GRCm39) |
M538L |
probably benign |
Het |
| Ppp3cb |
T |
C |
14: 20,570,714 (GRCm39) |
N339S |
possibly damaging |
Het |
| Rev1 |
T |
C |
1: 38,092,730 (GRCm39) |
E1202G |
probably damaging |
Het |
| Rngtt |
T |
A |
4: 33,339,133 (GRCm39) |
|
probably benign |
Het |
| Serpinb12 |
T |
A |
1: 106,876,883 (GRCm39) |
D66E |
probably benign |
Het |
| Sgsm1 |
A |
T |
5: 113,403,173 (GRCm39) |
F958Y |
probably damaging |
Het |
| Slc35e2 |
T |
C |
4: 155,702,106 (GRCm39) |
F290S |
probably benign |
Het |
| Sorl1 |
C |
T |
9: 41,943,210 (GRCm39) |
V889M |
possibly damaging |
Het |
| Sptlc3 |
G |
A |
2: 139,478,600 (GRCm39) |
V520I |
probably benign |
Het |
| Stam |
A |
T |
2: 14,120,669 (GRCm39) |
H53L |
probably damaging |
Het |
| Stox2 |
A |
G |
8: 47,645,970 (GRCm39) |
S497P |
probably damaging |
Het |
| Tarbp1 |
A |
G |
8: 127,201,069 (GRCm39) |
Y246H |
probably damaging |
Het |
| Tbx15 |
A |
G |
3: 99,259,683 (GRCm39) |
Y518C |
probably damaging |
Het |
| Tdrd5 |
T |
A |
1: 156,111,944 (GRCm39) |
T479S |
probably benign |
Het |
| Tescl |
T |
C |
7: 24,032,683 (GRCm39) |
E214G |
probably damaging |
Het |
| Tex10 |
T |
C |
4: 48,452,946 (GRCm39) |
D671G |
probably benign |
Het |
| Tmem132d |
A |
G |
5: 128,061,360 (GRCm39) |
V414A |
probably benign |
Het |
| Tmem41b |
T |
A |
7: 109,573,941 (GRCm39) |
|
probably benign |
Het |
| Tnfrsf18 |
A |
G |
4: 156,106,337 (GRCm39) |
|
probably benign |
Het |
| Tulp4 |
T |
A |
17: 6,249,108 (GRCm39) |
D42E |
probably damaging |
Het |
| Ubtd1 |
A |
G |
19: 42,022,103 (GRCm39) |
N125S |
probably damaging |
Het |
| Ubxn4 |
T |
A |
1: 128,183,186 (GRCm39) |
F68I |
probably benign |
Het |
| Urb1 |
A |
G |
16: 90,573,159 (GRCm39) |
S958P |
probably benign |
Het |
| Vash2 |
T |
C |
1: 190,692,498 (GRCm39) |
S226G |
probably benign |
Het |
| Vmn2r120 |
C |
T |
17: 57,816,120 (GRCm39) |
G745E |
probably damaging |
Het |
| Vmn2r58 |
T |
A |
7: 41,487,117 (GRCm39) |
I593F |
probably benign |
Het |
| Zfp398 |
T |
C |
6: 47,817,361 (GRCm39) |
L67P |
probably damaging |
Het |
| Zfp607b |
T |
A |
7: 27,403,120 (GRCm39) |
H525Q |
probably damaging |
Het |
| Zfp629 |
T |
C |
7: 127,211,492 (GRCm39) |
T106A |
probably benign |
Het |
| Zfp980 |
G |
A |
4: 145,428,653 (GRCm39) |
G461S |
probably benign |
Het |
| Zic5 |
T |
A |
14: 122,702,212 (GRCm39) |
D173V |
probably damaging |
Het |
| Zranb2 |
G |
A |
3: 157,247,521 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Nav1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01061:Nav1
|
APN |
1 |
135,378,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01455:Nav1
|
APN |
1 |
135,397,373 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL01650:Nav1
|
APN |
1 |
135,382,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01872:Nav1
|
APN |
1 |
135,381,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01967:Nav1
|
APN |
1 |
135,464,983 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02167:Nav1
|
APN |
1 |
135,398,699 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02278:Nav1
|
APN |
1 |
135,391,452 (GRCm39) |
splice site |
probably benign |
|
|
IGL02343:Nav1
|
APN |
1 |
135,382,490 (GRCm39) |
nonsense |
probably null |
|
|
IGL02378:Nav1
|
APN |
1 |
135,397,716 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02554:Nav1
|
APN |
1 |
135,512,651 (GRCm39) |
synonymous |
silent |
|
|
IGL03148:Nav1
|
APN |
1 |
135,397,762 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03286:Nav1
|
APN |
1 |
135,382,274 (GRCm39) |
missense |
probably benign |
|
|
IGL03372:Nav1
|
APN |
1 |
135,378,641 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4802001:Nav1
|
UTSW |
1 |
135,380,671 (GRCm39) |
missense |
unknown |
|
|
R0388:Nav1
|
UTSW |
1 |
135,376,655 (GRCm39) |
splice site |
probably benign |
|
|
R0390:Nav1
|
UTSW |
1 |
135,377,704 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0395:Nav1
|
UTSW |
1 |
135,460,361 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0395:Nav1
|
UTSW |
1 |
135,460,359 (GRCm39) |
nonsense |
probably null |
|
|
R0416:Nav1
|
UTSW |
1 |
135,398,864 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R0463:Nav1
|
UTSW |
1 |
135,379,945 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R0538:Nav1
|
UTSW |
1 |
135,392,430 (GRCm39) |
splice site |
probably benign |
|
|
R0594:Nav1
|
UTSW |
1 |
135,395,381 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R0696:Nav1
|
UTSW |
1 |
135,460,352 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0699:Nav1
|
UTSW |
1 |
135,380,687 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0759:Nav1
|
UTSW |
1 |
135,382,998 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1164:Nav1
|
UTSW |
1 |
135,400,148 (GRCm39) |
missense |
probably benign |
|
|
R1169:Nav1
|
UTSW |
1 |
135,382,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1401:Nav1
|
UTSW |
1 |
135,388,163 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1421:Nav1
|
UTSW |
1 |
135,512,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1642:Nav1
|
UTSW |
1 |
135,380,010 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1705:Nav1
|
UTSW |
1 |
135,512,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1713:Nav1
|
UTSW |
1 |
135,522,972 (GRCm39) |
intron |
probably benign |
|
|
R1728:Nav1
|
UTSW |
1 |
135,512,465 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1729:Nav1
|
UTSW |
1 |
135,512,465 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1730:Nav1
|
UTSW |
1 |
135,512,465 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1739:Nav1
|
UTSW |
1 |
135,512,465 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1740:Nav1
|
UTSW |
1 |
135,386,127 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1762:Nav1
|
UTSW |
1 |
135,512,465 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1783:Nav1
|
UTSW |
1 |
135,512,465 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1784:Nav1
|
UTSW |
1 |
135,512,465 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1785:Nav1
|
UTSW |
1 |
135,512,465 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1895:Nav1
|
UTSW |
1 |
135,386,396 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1896:Nav1
|
UTSW |
1 |
135,388,475 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1901:Nav1
|
UTSW |
1 |
135,400,148 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1902:Nav1
|
UTSW |
1 |
135,400,148 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1925:Nav1
|
UTSW |
1 |
135,534,967 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R1939:Nav1
|
UTSW |
1 |
135,393,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1971:Nav1
|
UTSW |
1 |
135,460,091 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2063:Nav1
|
UTSW |
1 |
135,376,742 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2066:Nav1
|
UTSW |
1 |
135,376,742 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2084:Nav1
|
UTSW |
1 |
135,535,158 (GRCm39) |
unclassified |
probably benign |
|
|
R2090:Nav1
|
UTSW |
1 |
135,534,903 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R2107:Nav1
|
UTSW |
1 |
135,376,742 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2110:Nav1
|
UTSW |
1 |
135,376,742 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2111:Nav1
|
UTSW |
1 |
135,376,742 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2112:Nav1
|
UTSW |
1 |
135,376,742 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2136:Nav1
|
UTSW |
1 |
135,382,174 (GRCm39) |
missense |
probably null |
0.18 |
|
R2268:Nav1
|
UTSW |
1 |
135,399,974 (GRCm39) |
nonsense |
probably null |
|
|
R2269:Nav1
|
UTSW |
1 |
135,399,974 (GRCm39) |
nonsense |
probably null |
|
|
R2847:Nav1
|
UTSW |
1 |
135,378,382 (GRCm39) |
splice site |
probably null |
|
|
R2869:Nav1
|
UTSW |
1 |
135,388,495 (GRCm39) |
synonymous |
silent |
|
|
R2871:Nav1
|
UTSW |
1 |
135,388,495 (GRCm39) |
synonymous |
silent |
|
|
R2872:Nav1
|
UTSW |
1 |
135,388,495 (GRCm39) |
synonymous |
silent |
|
|
R2904:Nav1
|
UTSW |
1 |
135,512,976 (GRCm39) |
missense |
probably benign |
|
|
R3690:Nav1
|
UTSW |
1 |
135,395,382 (GRCm39) |
missense |
probably benign |
0.11 |
|
R3716:Nav1
|
UTSW |
1 |
135,378,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3717:Nav1
|
UTSW |
1 |
135,378,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3718:Nav1
|
UTSW |
1 |
135,378,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3815:Nav1
|
UTSW |
1 |
135,398,862 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4282:Nav1
|
UTSW |
1 |
135,385,651 (GRCm39) |
intron |
probably benign |
|
|
R4361:Nav1
|
UTSW |
1 |
135,535,175 (GRCm39) |
unclassified |
probably benign |
|
|
R4730:Nav1
|
UTSW |
1 |
135,535,049 (GRCm39) |
unclassified |
probably benign |
|
|
R4784:Nav1
|
UTSW |
1 |
135,386,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4788:Nav1
|
UTSW |
1 |
135,397,461 (GRCm39) |
missense |
probably benign |
|
|
R4808:Nav1
|
UTSW |
1 |
135,382,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4996:Nav1
|
UTSW |
1 |
135,393,709 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5284:Nav1
|
UTSW |
1 |
135,377,701 (GRCm39) |
nonsense |
probably null |
|
|
R5514:Nav1
|
UTSW |
1 |
135,398,299 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5769:Nav1
|
UTSW |
1 |
135,379,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5834:Nav1
|
UTSW |
1 |
135,460,144 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5898:Nav1
|
UTSW |
1 |
135,512,884 (GRCm39) |
missense |
probably benign |
|
|
R6081:Nav1
|
UTSW |
1 |
135,398,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6344:Nav1
|
UTSW |
1 |
135,378,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6378:Nav1
|
UTSW |
1 |
135,382,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7001:Nav1
|
UTSW |
1 |
135,382,349 (GRCm39) |
splice site |
probably null |
|
|
R7185:Nav1
|
UTSW |
1 |
135,398,746 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7291:Nav1
|
UTSW |
1 |
135,393,597 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7361:Nav1
|
UTSW |
1 |
135,380,591 (GRCm39) |
missense |
unknown |
|
|
R7390:Nav1
|
UTSW |
1 |
135,512,656 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7464:Nav1
|
UTSW |
1 |
135,512,647 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7502:Nav1
|
UTSW |
1 |
135,397,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7601:Nav1
|
UTSW |
1 |
135,388,176 (GRCm39) |
missense |
unknown |
|
|
R7625:Nav1
|
UTSW |
1 |
135,395,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7639:Nav1
|
UTSW |
1 |
135,398,860 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7786:Nav1
|
UTSW |
1 |
135,397,733 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7808:Nav1
|
UTSW |
1 |
135,379,986 (GRCm39) |
missense |
unknown |
|
|
R7815:Nav1
|
UTSW |
1 |
135,512,377 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R7825:Nav1
|
UTSW |
1 |
135,377,782 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8030:Nav1
|
UTSW |
1 |
135,464,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8370:Nav1
|
UTSW |
1 |
135,398,882 (GRCm39) |
nonsense |
probably null |
|
|
R8405:Nav1
|
UTSW |
1 |
135,382,508 (GRCm39) |
missense |
unknown |
|
|
R8720:Nav1
|
UTSW |
1 |
135,388,464 (GRCm39) |
missense |
unknown |
|
|
R8868:Nav1
|
UTSW |
1 |
135,512,943 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8973:Nav1
|
UTSW |
1 |
135,512,463 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9039:Nav1
|
UTSW |
1 |
135,371,487 (GRCm39) |
missense |
unknown |
|
|
R9261:Nav1
|
UTSW |
1 |
135,388,095 (GRCm39) |
missense |
unknown |
|
|
R9523:Nav1
|
UTSW |
1 |
135,379,929 (GRCm39) |
missense |
unknown |
|
|
Z1088:Nav1
|
UTSW |
1 |
135,398,462 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1176:Nav1
|
UTSW |
1 |
135,400,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Nav1
|
UTSW |
1 |
135,380,624 (GRCm39) |
missense |
unknown |
|
|
Z1177:Nav1
|
UTSW |
1 |
135,397,469 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTATGACAAGTGTTCTGGACCC -3'
(R):5'- AGCATTAGGGGCCATGGTTG -3'
Sequencing Primer
(F):5'- GAGTACACTGTAGCTGTCTTCAGAC -3'
(R):5'- CCATGGTTGCCAGGAGATG -3'
|
| Posted On |
2016-04-01 |
Incidental Mutation