Mutagenetix > Incidental Mutation

Incidental Mutation 'R5043:Dnah12'

393315

Institutional Source

Beutler Lab

Gene Symbol

Dnah12

Ensembl Gene

ENSMUSG00000021879

Gene Name

dynein, axonemal, heavy chain 12

Synonyms

DHC3, Hdhc3, HL-19, Dnahc7l, 4921531P07Rik, LOC380889, DLP12, HL19, Dnahc12

MMRRC Submission

042633-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.184) question?

Stock #

R5043 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

26693274-26891703 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 26884190 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Serine to Leucine at position 3776 (S3776L)

Ref Sequence

ENSEMBL: ENSMUSP00000022433 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000022433]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000022433
AA Change: S3776L

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000022433
Gene: ENSMUSG00000021879
AA Change: S3776L

Domain	Start	End	E-Value	Type
low complexity region	127	140	N/A	INTRINSIC
coiled coil region	588	666	N/A	INTRINSIC
Pfam:DHC_N2	676	1113	1.1e-147	PFAM
AAA	1268	1407	1.15e0	SMART
Pfam:AAA_5	1552	1695	1.5e-7	PFAM
Blast:AAA	1709	1827	2e-24	BLAST
Blast:AAA	1848	1898	1e-16	BLAST
AAA	1903	2051	5.42e-4	SMART
Pfam:AAA_8	2238	2316	2e-18	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000165269
AA Change: S1156L

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000130609
Gene: ENSMUSG00000021879
AA Change: S1156L

Domain	Start	End	E-Value	Type
Pfam:MT	1	248	5.7e-40	PFAM
Pfam:AAA_9	270	495	3.8e-96	PFAM
low complexity region	593	606	N/A	INTRINSIC
Pfam:Dynein_heavy	631	1336	2e-287	PFAM

Meta Mutation Damage Score

0.1160

Coding Region Coverage

1x: 99.1%
3x: 98.3%
10x: 96.3%
20x: 92.4%

Validation Efficiency

98% (44/45)

Allele List at MGI

Other mutations in this stock

Total: 40 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700018F24Rik	T	A	5: 145,044,100 (GRCm38)	Y106*	probably null	Het
1700061G19Rik	A	G	17: 56,885,198 (GRCm38)	Y587C	probably damaging	Het
Akap12	G	C	10: 4,355,047 (GRCm38)	G619A	probably damaging	Het
Arhgap29	A	G	3: 121,974,004 (GRCm38)	K32E	probably benign	Het
Capg	T	A	6: 72,558,254 (GRCm38)	Y253*	probably null	Het
Cntnap3	A	T	13: 64,794,348 (GRCm38)	F189L	probably damaging	Het
Cp	T	C	3: 19,973,917 (GRCm38)	S496P	probably benign	Het
Cxcl11	T	C	5: 92,363,152 (GRCm38)		probably null	Het
Dennd3	T	C	15: 73,527,936 (GRCm38)	L217P	probably benign	Het
Dip2c	G	T	13: 9,551,827 (GRCm38)	R274L	possibly damaging	Het
Emcn	A	G	3: 137,391,601 (GRCm38)	T94A	possibly damaging	Het
Fnip2	A	T	3: 79,492,867 (GRCm38)	Y397*	probably null	Het
Gabrp	T	C	11: 33,568,072 (GRCm38)	N79D	probably benign	Het
Glmp	T	G	3: 88,326,676 (GRCm38)		probably benign	Het
Gm12794	T	C	4: 101,940,524 (GRCm38)	F40L	possibly damaging	Het
Gm5921	C	T	9: 115,438,019 (GRCm38)		noncoding transcript	Het
Gm6483	A	G	8: 19,693,670 (GRCm38)	T104A	probably benign	Het
Ifi206	A	T	1: 173,486,718 (GRCm38)	M52K	probably damaging	Het
Iqcc	T	C	4: 129,618,277 (GRCm38)		probably benign	Het
Klra2	T	A	6: 131,220,172 (GRCm38)	H288L	probably benign	Het
Myo5b	T	C	18: 74,638,153 (GRCm38)		probably null	Het
Nisch	A	G	14: 31,176,465 (GRCm38)		probably benign	Het
Nlrp4c	A	G	7: 6,066,825 (GRCm38)	N575S	probably benign	Het
Olfr354	A	C	2: 36,906,965 (GRCm38)	R6S	probably benign	Het
Olfr913	A	G	9: 38,594,841 (GRCm38)	I207V	probably damaging	Het
Phlda1	T	A	10: 111,507,291 (GRCm38)	L296Q	unknown	Het
Rab36	G	A	10: 75,051,005 (GRCm38)	E182K	probably benign	Het
Rasa3	G	A	8: 13,570,368 (GRCm38)	T767M	possibly damaging	Het
Serpinb11	G	A	1: 107,369,465 (GRCm38)	V24M	probably damaging	Het
Slc7a14	T	G	3: 31,237,466 (GRCm38)	N221T	probably damaging	Het
Smg6	T	C	11: 74,929,895 (GRCm38)	S331P	possibly damaging	Het
Snx1	C	T	9: 66,097,436 (GRCm38)	A183T	probably benign	Het
Srpk2	T	C	5: 23,524,517 (GRCm38)	T375A	probably benign	Het
Tecpr1	T	C	5: 144,197,854 (GRCm38)		probably null	Het
Topaz1	A	T	9: 122,748,404 (GRCm38)	E126D	probably benign	Het
Ugt2b1	C	G	5: 86,917,644 (GRCm38)	C512S	possibly damaging	Het
Ugt2b37	C	T	5: 87,251,860 (GRCm38)	W263*	probably null	Het
Utp20	A	T	10: 88,798,746 (GRCm38)	M750K	possibly damaging	Het
Yeats2	A	T	16: 20,208,465 (GRCm38)	Q822L	probably damaging	Het
Zfp609	T	C	9: 65,700,827 (GRCm38)	Y1257C	probably damaging	Het

Other mutations in Dnah12

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01412:Dnah12	APN	14	26,771,005 (GRCm38)	missense	probably damaging	1.00
IGL01602:Dnah12	APN	14	26,710,275 (GRCm38)	splice site	probably benign
IGL01681:Dnah12	APN	14	26,722,160 (GRCm38)	missense	probably benign
IGL02082:Dnah12	APN	14	26,707,162 (GRCm38)	missense	possibly damaging	0.79
IGL02140:Dnah12	APN	14	26,716,577 (GRCm38)	missense	probably benign	0.20
IGL02170:Dnah12	APN	14	26,773,112 (GRCm38)	missense	probably damaging	0.99
IGL02174:Dnah12	APN	14	26,706,917 (GRCm38)	missense	probably benign	0.00
IGL02367:Dnah12	APN	14	26,709,161 (GRCm38)	missense	probably benign	0.30
IGL02418:Dnah12	APN	14	26,773,722 (GRCm38)	missense	probably damaging	1.00
IGL03039:Dnah12	APN	14	26,724,512 (GRCm38)	missense	probably benign	0.02
IGL03066:Dnah12	APN	14	26,697,398 (GRCm38)	missense	probably benign	0.06
drippings	UTSW	14	26,854,804 (GRCm38)	missense	probably damaging	1.00
grueben	UTSW	14	26,878,079 (GRCm38)	missense	probably damaging	1.00
BB010:Dnah12	UTSW	14	26,766,115 (GRCm38)	missense	probably benign	0.00
BB020:Dnah12	UTSW	14	26,766,115 (GRCm38)	missense	probably benign	0.00
F5770:Dnah12	UTSW	14	26,773,093 (GRCm38)	missense	possibly damaging	0.95
FR4304:Dnah12	UTSW	14	26,849,385 (GRCm38)	missense	probably damaging	1.00
FR4340:Dnah12	UTSW	14	26,849,385 (GRCm38)	missense	probably damaging	1.00
FR4342:Dnah12	UTSW	14	26,849,385 (GRCm38)	missense	probably damaging	1.00
FR4589:Dnah12	UTSW	14	26,849,385 (GRCm38)	missense	probably damaging	1.00
IGL03055:Dnah12	UTSW	14	26,872,740 (GRCm38)	missense	probably damaging	1.00
LCD18:Dnah12	UTSW	14	26,849,385 (GRCm38)	missense	probably damaging	1.00
R0003:Dnah12	UTSW	14	26,772,644 (GRCm38)	missense	probably damaging	1.00
R0110:Dnah12	UTSW	14	26,798,899 (GRCm38)	missense	probably damaging	1.00
R0302:Dnah12	UTSW	14	26,799,999 (GRCm38)	missense	probably damaging	1.00
R0355:Dnah12	UTSW	14	26,706,117 (GRCm38)	splice site	probably null
R0364:Dnah12	UTSW	14	26,724,473 (GRCm38)	missense	probably benign	0.10
R0469:Dnah12	UTSW	14	26,798,899 (GRCm38)	missense	probably damaging	1.00
R0558:Dnah12	UTSW	14	26,709,310 (GRCm38)	missense	probably benign	0.00
R0709:Dnah12	UTSW	14	26,884,265 (GRCm38)	splice site	probably benign
R0734:Dnah12	UTSW	14	26,800,013 (GRCm38)	missense	probably benign	0.00
R1273:Dnah12	UTSW	14	26,739,220 (GRCm38)	nonsense	probably null
R1496:Dnah12	UTSW	14	26,710,248 (GRCm38)	missense	probably benign
R1503:Dnah12	UTSW	14	26,773,692 (GRCm38)	missense	probably damaging	1.00
R1535:Dnah12	UTSW	14	26,816,322 (GRCm38)	missense	possibly damaging	0.91
R1608:Dnah12	UTSW	14	26,766,190 (GRCm38)	missense	probably damaging	1.00
R1682:Dnah12	UTSW	14	26,778,883 (GRCm38)	missense	possibly damaging	0.71
R1758:Dnah12	UTSW	14	26,766,114 (GRCm38)	missense	probably benign	0.02
R1826:Dnah12	UTSW	14	26,711,019 (GRCm38)	missense	probably benign	0.01
R1829:Dnah12	UTSW	14	26,800,075 (GRCm38)	missense	probably damaging	1.00
R1829:Dnah12	UTSW	14	26,773,023 (GRCm38)	missense	probably damaging	1.00
R1862:Dnah12	UTSW	14	26,709,257 (GRCm38)	missense	probably benign	0.30
R1862:Dnah12	UTSW	14	26,697,398 (GRCm38)	missense	probably benign	0.06
R1913:Dnah12	UTSW	14	26,792,264 (GRCm38)	splice site	probably null
R1933:Dnah12	UTSW	14	26,734,495 (GRCm38)	missense	probably damaging	0.98
R2006:Dnah12	UTSW	14	26,814,459 (GRCm38)	missense	possibly damaging	0.95
R2045:Dnah12	UTSW	14	26,781,528 (GRCm38)	missense	probably null	1.00
R2113:Dnah12	UTSW	14	26,766,141 (GRCm38)	missense	probably damaging	1.00
R2125:Dnah12	UTSW	14	26,724,458 (GRCm38)	nonsense	probably null
R2126:Dnah12	UTSW	14	26,724,458 (GRCm38)	nonsense	probably null
R2207:Dnah12	UTSW	14	26,781,787 (GRCm38)	missense	probably damaging	0.99
R2213:Dnah12	UTSW	14	26,739,330 (GRCm38)	missense	probably benign	0.06
R2511:Dnah12	UTSW	14	26,769,950 (GRCm38)	missense	possibly damaging	0.65
R2875:Dnah12	UTSW	14	26,876,950 (GRCm38)	missense	probably benign	0.05
R2875:Dnah12	UTSW	14	26,693,470 (GRCm38)	missense	probably benign	0.04
R3551:Dnah12	UTSW	14	26,770,972 (GRCm38)	missense	probably benign	0.01
R3713:Dnah12	UTSW	14	26,812,790 (GRCm38)	missense	probably benign
R3729:Dnah12	UTSW	14	26,706,065 (GRCm38)	missense	probably benign	0.02
R3799:Dnah12	UTSW	14	26,770,923 (GRCm38)	missense	probably damaging	1.00
R3846:Dnah12	UTSW	14	26,710,211 (GRCm38)	missense	probably benign	0.00
R3892:Dnah12	UTSW	14	26,856,616 (GRCm38)	missense	probably benign	0.03
R3921:Dnah12	UTSW	14	26,771,051 (GRCm38)	missense	probably damaging	1.00
R3940:Dnah12	UTSW	14	26,723,599 (GRCm38)	missense	probably benign
R4065:Dnah12	UTSW	14	26,770,448 (GRCm38)	missense	probably benign	0.02
R4113:Dnah12	UTSW	14	26,693,567 (GRCm38)	missense	probably damaging	0.98
R4249:Dnah12	UTSW	14	26,709,186 (GRCm38)	missense	possibly damaging	0.70
R4259:Dnah12	UTSW	14	26,798,926 (GRCm38)	missense	probably benign	0.01
R4260:Dnah12	UTSW	14	26,798,926 (GRCm38)	missense	probably benign	0.01
R4348:Dnah12	UTSW	14	26,814,541 (GRCm38)	missense	possibly damaging	0.94
R4457:Dnah12	UTSW	14	26,815,507 (GRCm38)	missense	probably damaging	1.00
R4490:Dnah12	UTSW	14	26,734,603 (GRCm38)	missense	possibly damaging	0.67
R4491:Dnah12	UTSW	14	26,734,603 (GRCm38)	missense	possibly damaging	0.67
R4494:Dnah12	UTSW	14	26,871,855 (GRCm38)	missense	probably damaging	0.99
R4523:Dnah12	UTSW	14	26,876,958 (GRCm38)	missense	possibly damaging	0.83
R4523:Dnah12	UTSW	14	26,770,022 (GRCm38)	missense	probably damaging	0.97
R4546:Dnah12	UTSW	14	26,773,014 (GRCm38)	missense	probably damaging	1.00
R4584:Dnah12	UTSW	14	26,772,594 (GRCm38)	missense	probably damaging	1.00
R4624:Dnah12	UTSW	14	26,735,758 (GRCm38)	missense	possibly damaging	0.82
R4689:Dnah12	UTSW	14	26,706,839 (GRCm38)	missense	probably benign	0.00
R4727:Dnah12	UTSW	14	26,872,317 (GRCm38)	missense	probably damaging	1.00
R4732:Dnah12	UTSW	14	26,781,784 (GRCm38)	missense	probably damaging	1.00
R4733:Dnah12	UTSW	14	26,781,784 (GRCm38)	missense	probably damaging	1.00
R4851:Dnah12	UTSW	14	26,716,629 (GRCm38)	nonsense	probably null
R4879:Dnah12	UTSW	14	26,718,046 (GRCm38)	critical splice donor site	probably null
R4893:Dnah12	UTSW	14	26,710,170 (GRCm38)	missense	possibly damaging	0.66
R4915:Dnah12	UTSW	14	26,734,570 (GRCm38)	missense	probably damaging	1.00
R4927:Dnah12	UTSW	14	26,861,805 (GRCm38)	nonsense	probably null
R4939:Dnah12	UTSW	14	26,891,524 (GRCm38)	missense	probably damaging	1.00
R4962:Dnah12	UTSW	14	26,716,700 (GRCm38)	missense	probably benign	0.00
R5011:Dnah12	UTSW	14	26,710,171 (GRCm38)	missense	probably benign	0.03
R5013:Dnah12	UTSW	14	26,710,171 (GRCm38)	missense	probably benign	0.03
R5049:Dnah12	UTSW	14	26,735,697 (GRCm38)	missense	probably benign	0.09
R5122:Dnah12	UTSW	14	26,718,000 (GRCm38)	missense	probably benign	0.00
R5135:Dnah12	UTSW	14	26,770,477 (GRCm38)	missense	probably damaging	0.99
R5149:Dnah12	UTSW	14	26,850,926 (GRCm38)	nonsense	probably null
R5154:Dnah12	UTSW	14	26,849,363 (GRCm38)	missense	probably benign	0.12
R5206:Dnah12	UTSW	14	26,769,985 (GRCm38)	missense	probably damaging	1.00
R5307:Dnah12	UTSW	14	26,693,486 (GRCm38)	missense	possibly damaging	0.49
R5330:Dnah12	UTSW	14	26,773,830 (GRCm38)	missense	probably damaging	1.00
R5335:Dnah12	UTSW	14	26,879,738 (GRCm38)	missense	probably damaging	1.00
R5339:Dnah12	UTSW	14	26,814,537 (GRCm38)	missense	possibly damaging	0.83
R5354:Dnah12	UTSW	14	26,774,342 (GRCm38)	splice site	probably null
R5389:Dnah12	UTSW	14	26,735,749 (GRCm38)	missense	probably damaging	1.00
R5434:Dnah12	UTSW	14	26,859,299 (GRCm38)	missense	probably damaging	1.00
R5466:Dnah12	UTSW	14	26,771,050 (GRCm38)	missense	probably damaging	1.00
R5655:Dnah12	UTSW	14	26,710,269 (GRCm38)	missense	probably benign	0.01
R5681:Dnah12	UTSW	14	26,815,495 (GRCm38)	missense	probably benign	0.32
R5824:Dnah12	UTSW	14	26,770,518 (GRCm38)	critical splice donor site	probably null
R5863:Dnah12	UTSW	14	26,854,921 (GRCm38)	missense	probably damaging	1.00
R5890:Dnah12	UTSW	14	26,706,884 (GRCm38)	missense	probably benign	0.09
R5912:Dnah12	UTSW	14	26,770,008 (GRCm38)	nonsense	probably null
R5916:Dnah12	UTSW	14	26,706,918 (GRCm38)	missense	possibly damaging	0.92
R5941:Dnah12	UTSW	14	26,706,867 (GRCm38)	missense	probably benign	0.00
R5987:Dnah12	UTSW	14	26,886,871 (GRCm38)	missense	possibly damaging	0.54
R5992:Dnah12	UTSW	14	26,697,341 (GRCm38)	missense	probably benign	0.04
R6132:Dnah12	UTSW	14	26,717,911 (GRCm38)	missense	probably damaging	1.00
R6136:Dnah12	UTSW	14	26,875,270 (GRCm38)	missense	probably damaging	0.99
R6158:Dnah12	UTSW	14	26,773,685 (GRCm38)	missense	possibly damaging	0.95
R6183:Dnah12	UTSW	14	26,861,769 (GRCm38)	missense	probably damaging	1.00
R6191:Dnah12	UTSW	14	26,710,257 (GRCm38)	missense	probably benign	0.03
R6235:Dnah12	UTSW	14	26,854,804 (GRCm38)	missense	probably damaging	1.00
R6277:Dnah12	UTSW	14	26,770,482 (GRCm38)	missense	probably damaging	1.00
R6332:Dnah12	UTSW	14	26,717,974 (GRCm38)	missense	probably damaging	0.99
R6334:Dnah12	UTSW	14	26,706,834 (GRCm38)	missense	possibly damaging	0.51
R6443:Dnah12	UTSW	14	26,878,051 (GRCm38)	missense	probably benign	0.06
R6480:Dnah12	UTSW	14	26,872,455 (GRCm38)	missense	probably damaging	1.00
R6530:Dnah12	UTSW	14	26,735,710 (GRCm38)	missense	probably damaging	1.00
R6678:Dnah12	UTSW	14	26,735,692 (GRCm38)	missense	probably damaging	1.00
R6709:Dnah12	UTSW	14	26,872,749 (GRCm38)	missense	probably damaging	1.00
R6724:Dnah12	UTSW	14	26,796,223 (GRCm38)	missense	probably benign	0.02
R6745:Dnah12	UTSW	14	26,707,228 (GRCm38)	missense	probably damaging	0.99
R6788:Dnah12	UTSW	14	26,801,513 (GRCm38)	missense	probably damaging	0.99
R6894:Dnah12	UTSW	14	26,735,749 (GRCm38)	missense	probably damaging	1.00
R6912:Dnah12	UTSW	14	26,878,079 (GRCm38)	missense	probably damaging	1.00
R6982:Dnah12	UTSW	14	26,799,076 (GRCm38)	splice site	probably null
R7001:Dnah12	UTSW	14	26,879,724 (GRCm38)	missense	probably damaging	0.99
R7002:Dnah12	UTSW	14	26,876,998 (GRCm38)	missense	probably damaging	1.00
R7017:Dnah12	UTSW	14	26,735,680 (GRCm38)	missense	probably benign
R7107:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7108:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7121:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7122:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7135:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7135:Dnah12	UTSW	14	26,801,413 (GRCm38)	missense	probably damaging	0.99
R7150:Dnah12	UTSW	14	26,861,732 (GRCm38)	missense	probably damaging	0.99
R7188:Dnah12	UTSW	14	26,814,413 (GRCm38)	missense	probably benign	0.04
R7201:Dnah12	UTSW	14	26,814,622 (GRCm38)	missense	probably benign	0.08
R7202:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7204:Dnah12	UTSW	14	26,781,485 (GRCm38)	missense	probably damaging	0.99
R7204:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7205:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7206:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7219:Dnah12	UTSW	14	26,854,880 (GRCm38)	missense	probably damaging	0.99
R7337:Dnah12	UTSW	14	26,766,577 (GRCm38)	splice site	probably null
R7339:Dnah12	UTSW	14	26,872,320 (GRCm38)	missense	probably benign
R7363:Dnah12	UTSW	14	26,724,611 (GRCm38)	missense	probably benign
R7426:Dnah12	UTSW	14	26,724,626 (GRCm38)	missense	probably benign	0.01
R7472:Dnah12	UTSW	14	26,856,635 (GRCm38)	missense	probably benign	0.01
R7579:Dnah12	UTSW	14	26,770,503 (GRCm38)	missense	probably benign	0.05
R7655:Dnah12	UTSW	14	26,859,316 (GRCm38)	missense	probably benign	0.21
R7656:Dnah12	UTSW	14	26,859,316 (GRCm38)	missense	probably benign	0.21
R7694:Dnah12	UTSW	14	26,781,380 (GRCm38)	missense	probably damaging	1.00
R7730:Dnah12	UTSW	14	26,785,933 (GRCm38)	missense	probably damaging	1.00
R7837:Dnah12	UTSW	14	26,796,219 (GRCm38)	missense	probably benign	0.01
R7855:Dnah12	UTSW	14	26,829,329 (GRCm38)	missense	probably benign	0.14
R7870:Dnah12	UTSW	14	26,856,529 (GRCm38)	missense	probably benign	0.00
R7920:Dnah12	UTSW	14	26,856,542 (GRCm38)	missense	possibly damaging	0.58
R7933:Dnah12	UTSW	14	26,766,115 (GRCm38)	missense	probably benign	0.00
R7956:Dnah12	UTSW	14	26,709,272 (GRCm38)	missense	probably damaging	0.96
R8192:Dnah12	UTSW	14	26,706,881 (GRCm38)	missense	probably benign
R8263:Dnah12	UTSW	14	26,891,464 (GRCm38)	missense	noncoding transcript
R8287:Dnah12	UTSW	14	26,812,603 (GRCm38)	missense	probably benign
R8336:Dnah12	UTSW	14	26,711,065 (GRCm38)	missense	probably benign	0.01
R8362:Dnah12	UTSW	14	26,854,831 (GRCm38)	missense	probably damaging	1.00
R8392:Dnah12	UTSW	14	26,885,912 (GRCm38)	missense	probably benign
R8458:Dnah12	UTSW	14	26,826,892 (GRCm38)	critical splice acceptor site	probably null
R8481:Dnah12	UTSW	14	26,853,796 (GRCm38)	missense	probably benign	0.02
R8551:Dnah12	UTSW	14	26,774,270 (GRCm38)	missense	probably damaging	0.97
R8669:Dnah12	UTSW	14	26,830,625 (GRCm38)	splice site	probably benign
R8698:Dnah12	UTSW	14	26,707,263 (GRCm38)	missense	probably benign	0.02
R8709:Dnah12	UTSW	14	26,693,602 (GRCm38)	missense	probably benign	0.00
R8778:Dnah12	UTSW	14	26,734,563 (GRCm38)	missense	probably benign	0.29
R9049:Dnah12	UTSW	14	26,722,120 (GRCm38)	missense	probably benign	0.00
R9087:Dnah12	UTSW	14	26,824,546 (GRCm38)	missense	probably damaging	1.00
R9099:Dnah12	UTSW	14	26,770,368 (GRCm38)	missense	probably benign	0.31
R9153:Dnah12	UTSW	14	26,814,612 (GRCm38)	missense	probably damaging	1.00
R9177:Dnah12	UTSW	14	26,849,298 (GRCm38)	missense	possibly damaging	0.84
R9214:Dnah12	UTSW	14	26,723,905 (GRCm38)	missense	probably benign	0.02
R9268:Dnah12	UTSW	14	26,849,298 (GRCm38)	missense	possibly damaging	0.84
R9274:Dnah12	UTSW	14	26,815,417 (GRCm38)	missense	probably benign	0.00
R9293:Dnah12	UTSW	14	26,773,059 (GRCm38)	missense	probably benign
R9322:Dnah12	UTSW	14	26,770,977 (GRCm38)	missense	possibly damaging	0.75
R9353:Dnah12	UTSW	14	26,856,550 (GRCm38)	missense	probably damaging	1.00
R9506:Dnah12	UTSW	14	26,792,211 (GRCm38)	missense	probably benign	0.00
R9518:Dnah12	UTSW	14	26,773,756 (GRCm38)	missense	probably damaging	1.00
R9524:Dnah12	UTSW	14	26,850,537 (GRCm38)	missense	probably null	0.91
R9562:Dnah12	UTSW	14	26,875,324 (GRCm38)	missense	possibly damaging	0.58
R9565:Dnah12	UTSW	14	26,875,324 (GRCm38)	missense	possibly damaging	0.58
R9573:Dnah12	UTSW	14	26,693,464 (GRCm38)	missense	probably benign
R9581:Dnah12	UTSW	14	26,770,028 (GRCm38)	missense	probably damaging	1.00
R9689:Dnah12	UTSW	14	26,868,914 (GRCm38)	missense	probably null	1.00
R9727:Dnah12	UTSW	14	26,801,553 (GRCm38)	nonsense	probably null
V7580:Dnah12	UTSW	14	26,773,093 (GRCm38)	missense	possibly damaging	0.95
V7581:Dnah12	UTSW	14	26,773,093 (GRCm38)	missense	possibly damaging	0.95
X0018:Dnah12	UTSW	14	26,814,480 (GRCm38)	missense	probably damaging	1.00
X0027:Dnah12	UTSW	14	26,816,288 (GRCm38)	missense	probably damaging	1.00
X0065:Dnah12	UTSW	14	26,814,645 (GRCm38)	missense	possibly damaging	0.93
Z1177:Dnah12	UTSW	14	26,875,215 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TTGCAGATTGTACATTGATGCG -3'
(R):5'- ACTGCACTATGTGGTCATTTGG -3'

Sequencing Primer
(F):5'- CAGATTGTACATTGATGCGTACTATC -3'
(R):5'- GGTCATTTGGGGCAATATTTTCAC -3'

Posted On

2016-06-15