Incidental Mutation 'R7831:Clip1'
| ID |
605609 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Clip1
|
| Ensembl Gene |
ENSMUSG00000049550 |
| Gene Name |
CAP-GLY domain containing linker protein 1 |
| Synonyms |
Rsn, CLIP-170, 4631429H07Rik, restin, Clip 170, 1110007I12Rik, Clip50, cytoplasmic linker protein 50 |
| MMRRC Submission |
045885-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7831 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
123715857-123822527 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 123751342 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Lysine
at position 813
(M813K)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000031382]
[ENSMUST00000063905]
[ENSMUST00000111561]
[ENSMUST00000111564]
[ENSMUST00000111566]
[ENSMUST00000149410]
|
| AlphaFold |
Q922J3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000031382
|
| SMART Domains |
Protein: ENSMUSP00000031382
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2.28e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2.28e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
451 |
N/A |
INTRINSIC |
|
coiled coil region
|
474 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
581 |
620 |
N/A |
INTRINSIC |
|
coiled coil region
|
652 |
1352 |
N/A |
INTRINSIC |
|
low complexity region
|
1362 |
1373 |
N/A |
INTRINSIC |
|
Pfam:CLIP1_ZNF
|
1375 |
1392 |
5.8e-9 |
PFAM |
|
ZnF_C2HC
|
1417 |
1433 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000063905
|
| SMART Domains |
Protein: ENSMUSP00000068241
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
3.3e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
3.3e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
524 |
N/A |
INTRINSIC |
|
coiled coil region
|
570 |
609 |
N/A |
INTRINSIC |
|
coiled coil region
|
641 |
1075 |
N/A |
INTRINSIC |
|
coiled coil region
|
1115 |
1235 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1256 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1300 |
1316 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111561
|
| SMART Domains |
Protein: ENSMUSP00000107186
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
1.93e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
1.93e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
524 |
N/A |
INTRINSIC |
|
coiled coil region
|
570 |
609 |
N/A |
INTRINSIC |
|
coiled coil region
|
641 |
1341 |
N/A |
INTRINSIC |
|
low complexity region
|
1351 |
1362 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1406 |
1422 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111564
|
| SMART Domains |
Protein: ENSMUSP00000107190
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2.5e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2.5e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
489 |
N/A |
INTRINSIC |
|
coiled coil region
|
535 |
574 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
1230 |
N/A |
INTRINSIC |
|
low complexity region
|
1240 |
1251 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1295 |
1311 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111566
|
| SMART Domains |
Protein: ENSMUSP00000107192
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
489 |
N/A |
INTRINSIC |
|
coiled coil region
|
535 |
574 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
1306 |
N/A |
INTRINSIC |
|
low complexity region
|
1316 |
1327 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1371 |
1387 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000137363
|
| SMART Domains |
Protein: ENSMUSP00000121425
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
CAP_GLY
|
2 |
31 |
2.59e0 |
SMART |
|
low complexity region
|
39 |
57 |
N/A |
INTRINSIC |
|
low complexity region
|
58 |
84 |
N/A |
INTRINSIC |
|
coiled coil region
|
101 |
276 |
N/A |
INTRINSIC |
|
coiled coil region
|
322 |
361 |
N/A |
INTRINSIC |
|
coiled coil region
|
393 |
980 |
N/A |
INTRINSIC |
|
low complexity region
|
991 |
1002 |
N/A |
INTRINSIC |
|
Pfam:CLIP1_ZNF
|
1004 |
1021 |
4.2e-9 |
PFAM |
|
ZnF_C2HC
|
1046 |
1062 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000144121
|
| SMART Domains |
Protein: ENSMUSP00000119641
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
CAP_GLY
|
37 |
102 |
1.05e-31 |
SMART |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000122064
Gene: ENSMUSG00000049550
AA Change: M813K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
43 |
59 |
N/A |
INTRINSIC |
|
low complexity region
|
165 |
176 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
352 |
375 |
1.56e-8 |
PROSPERO |
|
internal_repeat_3
|
358 |
377 |
5.32e-6 |
PROSPERO |
|
internal_repeat_1
|
450 |
473 |
1.56e-8 |
PROSPERO |
|
internal_repeat_3
|
544 |
563 |
5.32e-6 |
PROSPERO |
|
internal_repeat_2
|
553 |
575 |
2.88e-7 |
PROSPERO |
|
low complexity region
|
735 |
744 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
781 |
803 |
2.88e-7 |
PROSPERO |
|
low complexity region
|
819 |
830 |
N/A |
INTRINSIC |
|
low complexity region
|
962 |
977 |
N/A |
INTRINSIC |
|
low complexity region
|
1081 |
1099 |
N/A |
INTRINSIC |
|
low complexity region
|
1110 |
1121 |
N/A |
INTRINSIC |
|
low complexity region
|
1164 |
1175 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000149410
|
| SMART Domains |
Protein: ENSMUSP00000115965
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
26 |
32 |
N/A |
INTRINSIC |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
334 |
458 |
N/A |
INTRINSIC |
|
coiled coil region
|
504 |
543 |
N/A |
INTRINSIC |
|
coiled coil region
|
575 |
827 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
100% (87/87) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
PHENOTYPE: Mice homozygous for a targeted allele display reduced male fertility and teratozoospermia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca13 |
G |
A |
11: 9,247,404 (GRCm39) |
V2384I |
possibly damaging |
Het |
| Acsl1 |
A |
G |
8: 46,972,043 (GRCm39) |
D297G |
probably benign |
Het |
| Ap2a1 |
C |
A |
7: 44,550,436 (GRCm39) |
R944L |
probably damaging |
Het |
| Apbb1ip |
A |
G |
2: 22,756,933 (GRCm39) |
Y398C |
probably damaging |
Het |
| Atp8a2 |
A |
T |
14: 60,011,202 (GRCm39) |
V968D |
probably damaging |
Het |
| Becn1 |
T |
C |
11: 101,181,279 (GRCm39) |
T341A |
probably benign |
Het |
| Card11 |
G |
T |
5: 140,859,167 (GRCm39) |
S1126R |
possibly damaging |
Het |
| Ccdc51 |
T |
C |
9: 108,921,058 (GRCm39) |
L315S |
probably damaging |
Het |
| Cdk12 |
T |
C |
11: 98,140,653 (GRCm39) |
L1298P |
unknown |
Het |
| Cep170b |
A |
T |
12: 112,711,234 (GRCm39) |
D1538V |
probably benign |
Het |
| Cfap52 |
A |
T |
11: 67,826,782 (GRCm39) |
F348I |
possibly damaging |
Het |
| Col19a1 |
G |
A |
1: 24,565,563 (GRCm39) |
T256I |
unknown |
Het |
| Col6a3 |
A |
T |
1: 90,724,268 (GRCm39) |
C2027* |
probably null |
Het |
| Crisp4 |
A |
T |
1: 18,199,013 (GRCm39) |
N140K |
probably benign |
Het |
| Crocc2 |
G |
T |
1: 93,143,195 (GRCm39) |
A1266S |
probably benign |
Het |
| Cyfip2 |
G |
A |
11: 46,087,273 (GRCm39) |
R1206C |
probably damaging |
Het |
| Cyp24a1 |
T |
A |
2: 170,327,860 (GRCm39) |
M461L |
probably damaging |
Het |
| Cyp2a5 |
C |
T |
7: 26,534,940 (GRCm39) |
T51I |
possibly damaging |
Het |
| Cyp2b19 |
C |
T |
7: 26,466,565 (GRCm39) |
H398Y |
possibly damaging |
Het |
| Cyp4a29 |
G |
A |
4: 115,107,367 (GRCm39) |
V234I |
probably benign |
Het |
| Dicer1 |
T |
G |
12: 104,675,059 (GRCm39) |
K734N |
probably damaging |
Het |
| Dnai1 |
T |
C |
4: 41,614,695 (GRCm39) |
|
probably null |
Het |
| Entpd3 |
G |
A |
9: 120,373,025 (GRCm39) |
G14D |
probably damaging |
Het |
| Entrep3 |
G |
A |
3: 89,091,520 (GRCm39) |
|
probably null |
Het |
| Ermp1 |
T |
C |
19: 29,595,367 (GRCm39) |
T634A |
probably benign |
Het |
| Evc |
C |
T |
5: 37,476,427 (GRCm39) |
G374D |
probably damaging |
Het |
| Fcgbp |
C |
A |
7: 27,806,404 (GRCm39) |
T2124K |
probably damaging |
Het |
| Fgf8 |
G |
A |
19: 45,730,876 (GRCm39) |
P50S |
probably benign |
Het |
| Fmnl1 |
C |
T |
11: 103,088,999 (GRCm39) |
R1074W |
unknown |
Het |
| Galnt18 |
C |
T |
7: 111,155,665 (GRCm39) |
V223M |
possibly damaging |
Het |
| Galnt2 |
A |
G |
8: 125,058,817 (GRCm39) |
N295S |
probably benign |
Het |
| Grip1 |
T |
G |
10: 119,854,011 (GRCm39) |
V600G |
probably damaging |
Het |
| Insm2 |
T |
A |
12: 55,647,323 (GRCm39) |
C356S |
probably damaging |
Het |
| Itpr2 |
T |
A |
6: 146,193,082 (GRCm39) |
I1672F |
probably benign |
Het |
| Kdm1b |
T |
G |
13: 47,204,098 (GRCm39) |
N76K |
probably benign |
Het |
| Khnyn |
T |
A |
14: 56,125,303 (GRCm39) |
|
probably null |
Het |
| Kidins220 |
C |
T |
12: 25,111,230 (GRCm39) |
A1167V |
possibly damaging |
Het |
| Krt40 |
T |
C |
11: 99,432,087 (GRCm39) |
D208G |
probably benign |
Het |
| Lars1 |
T |
A |
18: 42,350,627 (GRCm39) |
D894V |
probably benign |
Het |
| Lmx1a |
A |
T |
1: 167,668,521 (GRCm39) |
N266I |
probably benign |
Het |
| Mrgprb5 |
T |
A |
7: 47,817,997 (GRCm39) |
K246M |
probably benign |
Het |
| Mrpl2 |
G |
A |
17: 46,959,598 (GRCm39) |
G176R |
possibly damaging |
Het |
| Muc21 |
T |
A |
17: 35,929,651 (GRCm39) |
T1512S |
unknown |
Het |
| Nell1 |
T |
A |
7: 49,632,548 (GRCm39) |
F60L |
possibly damaging |
Het |
| Nnt |
G |
A |
13: 119,506,630 (GRCm39) |
A453V |
possibly damaging |
Het |
| Opa1 |
A |
G |
16: 29,467,755 (GRCm39) |
K940R |
probably benign |
Het |
| Opn5 |
A |
C |
17: 42,891,510 (GRCm39) |
I309S |
probably null |
Het |
| Or1af1 |
C |
T |
2: 37,109,723 (GRCm39) |
T74I |
probably damaging |
Het |
| Or1r1 |
A |
C |
11: 73,875,257 (GRCm39) |
M59R |
probably damaging |
Het |
| Or2ag15 |
T |
A |
7: 106,340,620 (GRCm39) |
I174F |
probably damaging |
Het |
| P3h3 |
T |
G |
6: 124,832,118 (GRCm39) |
E256A |
possibly damaging |
Het |
| Pald1 |
G |
T |
10: 61,191,593 (GRCm39) |
T65K |
probably damaging |
Het |
| Pcnx3 |
T |
C |
19: 5,735,989 (GRCm39) |
Y279C |
probably damaging |
Het |
| Pik3c2b |
G |
A |
1: 132,998,980 (GRCm39) |
S367N |
possibly damaging |
Het |
| Pik3cb |
T |
C |
9: 98,970,666 (GRCm39) |
T342A |
probably benign |
Het |
| Pkd1l3 |
A |
T |
8: 110,357,990 (GRCm39) |
E837D |
possibly damaging |
Het |
| Ppp2r2b |
T |
A |
18: 42,834,597 (GRCm39) |
Y191F |
probably benign |
Het |
| Ppp4r4 |
G |
A |
12: 103,557,080 (GRCm39) |
E439K |
possibly damaging |
Het |
| Ptprk |
A |
G |
10: 28,444,404 (GRCm39) |
I946V |
possibly damaging |
Het |
| Ror1 |
A |
G |
4: 100,298,295 (GRCm39) |
N556S |
probably benign |
Het |
| Ryr3 |
C |
T |
2: 112,757,183 (GRCm39) |
A391T |
possibly damaging |
Het |
| Selp |
G |
A |
1: 163,972,584 (GRCm39) |
|
probably null |
Het |
| Setx |
T |
C |
2: 29,047,120 (GRCm39) |
L1866S |
probably damaging |
Het |
| Setx |
T |
A |
2: 29,069,866 (GRCm39) |
V2557E |
possibly damaging |
Het |
| Slc66a3 |
T |
A |
12: 17,047,632 (GRCm39) |
|
probably null |
Het |
| Slit2 |
A |
G |
5: 48,402,025 (GRCm39) |
T805A |
probably benign |
Het |
| Sorbs3 |
T |
G |
14: 70,440,481 (GRCm39) |
N89T |
possibly damaging |
Het |
| Sorl1 |
C |
A |
9: 42,001,257 (GRCm39) |
V248L |
probably benign |
Het |
| Srebf2 |
T |
A |
15: 82,066,288 (GRCm39) |
V612E |
probably damaging |
Het |
| Sv2c |
T |
A |
13: 96,113,200 (GRCm39) |
Y583F |
probably damaging |
Het |
| Tada1 |
G |
T |
1: 166,217,442 (GRCm39) |
R193I |
probably damaging |
Het |
| Tnrc6b |
C |
G |
15: 80,764,580 (GRCm39) |
A694G |
possibly damaging |
Het |
| Ttll3 |
CAAAGTAA |
CAAAGTAAAGTAA |
6: 113,376,118 (GRCm39) |
|
probably null |
Het |
| Ttn |
C |
T |
2: 76,711,425 (GRCm39) |
G8372D |
unknown |
Het |
| Ube2g2 |
A |
G |
10: 77,470,576 (GRCm39) |
T68A |
|
Het |
| Ubl7 |
T |
G |
9: 57,821,918 (GRCm39) |
V89G |
possibly damaging |
Het |
| Ush2a |
T |
A |
1: 188,492,038 (GRCm39) |
I3109N |
probably damaging |
Het |
| Utp20 |
T |
A |
10: 88,598,632 (GRCm39) |
K115* |
probably null |
Het |
| Vmn2r26 |
T |
A |
6: 124,016,758 (GRCm39) |
Y407* |
probably null |
Het |
| Yod1 |
G |
T |
1: 130,646,986 (GRCm39) |
V288F |
probably damaging |
Het |
| Zbed5 |
A |
C |
5: 129,930,798 (GRCm39) |
N249T |
possibly damaging |
Het |
| Zbtb5 |
T |
C |
4: 44,995,244 (GRCm39) |
T47A |
probably damaging |
Het |
| Zcchc14 |
T |
C |
8: 122,331,984 (GRCm39) |
T460A |
not run |
Het |
| Zfp712 |
A |
C |
13: 67,200,483 (GRCm39) |
|
probably null |
Het |
| Zfyve16 |
A |
T |
13: 92,658,836 (GRCm39) |
H358Q |
probably benign |
Het |
|
| Other mutations in Clip1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00159:Clip1
|
APN |
5 |
123,741,717 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01067:Clip1
|
APN |
5 |
123,768,867 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01524:Clip1
|
APN |
5 |
123,717,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01632:Clip1
|
APN |
5 |
123,755,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01798:Clip1
|
APN |
5 |
123,721,612 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01874:Clip1
|
APN |
5 |
123,741,729 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL01908:Clip1
|
APN |
5 |
123,761,270 (GRCm39) |
splice site |
probably benign |
|
|
IGL02120:Clip1
|
APN |
5 |
123,785,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02309:Clip1
|
APN |
5 |
123,755,763 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02555:Clip1
|
APN |
5 |
123,759,857 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03027:Clip1
|
APN |
5 |
123,759,919 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL03336:Clip1
|
APN |
5 |
123,791,633 (GRCm39) |
nonsense |
probably null |
|
|
IGL03365:Clip1
|
APN |
5 |
123,721,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02802:Clip1
|
UTSW |
5 |
123,769,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4812001:Clip1
|
UTSW |
5 |
123,768,738 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0254:Clip1
|
UTSW |
5 |
123,755,395 (GRCm39) |
splice site |
probably benign |
|
|
R0401:Clip1
|
UTSW |
5 |
123,791,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0530:Clip1
|
UTSW |
5 |
123,778,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0744:Clip1
|
UTSW |
5 |
123,768,784 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0833:Clip1
|
UTSW |
5 |
123,768,784 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1116:Clip1
|
UTSW |
5 |
123,717,554 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1182:Clip1
|
UTSW |
5 |
123,785,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1656:Clip1
|
UTSW |
5 |
123,768,466 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1700:Clip1
|
UTSW |
5 |
123,768,433 (GRCm39) |
missense |
probably benign |
|
|
R1889:Clip1
|
UTSW |
5 |
123,791,559 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1975:Clip1
|
UTSW |
5 |
123,761,281 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2406:Clip1
|
UTSW |
5 |
123,741,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3545:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3547:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3548:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3911:Clip1
|
UTSW |
5 |
123,728,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3944:Clip1
|
UTSW |
5 |
123,755,892 (GRCm39) |
unclassified |
probably benign |
|
|
R4660:Clip1
|
UTSW |
5 |
123,717,437 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4784:Clip1
|
UTSW |
5 |
123,717,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4785:Clip1
|
UTSW |
5 |
123,717,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4824:Clip1
|
UTSW |
5 |
123,769,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4831:Clip1
|
UTSW |
5 |
123,721,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4951:Clip1
|
UTSW |
5 |
123,768,408 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4960:Clip1
|
UTSW |
5 |
123,792,066 (GRCm39) |
nonsense |
probably null |
|
|
R5014:Clip1
|
UTSW |
5 |
123,755,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5116:Clip1
|
UTSW |
5 |
123,768,770 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5212:Clip1
|
UTSW |
5 |
123,768,744 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5238:Clip1
|
UTSW |
5 |
123,785,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5318:Clip1
|
UTSW |
5 |
123,751,147 (GRCm39) |
unclassified |
probably benign |
|
|
R5372:Clip1
|
UTSW |
5 |
123,768,303 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5701:Clip1
|
UTSW |
5 |
123,751,366 (GRCm39) |
unclassified |
probably benign |
|
|
R5734:Clip1
|
UTSW |
5 |
123,753,217 (GRCm39) |
unclassified |
probably benign |
|
|
R5757:Clip1
|
UTSW |
5 |
123,765,460 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6024:Clip1
|
UTSW |
5 |
123,753,152 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6160:Clip1
|
UTSW |
5 |
123,751,604 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6177:Clip1
|
UTSW |
5 |
123,751,897 (GRCm39) |
unclassified |
probably benign |
|
|
R6183:Clip1
|
UTSW |
5 |
123,780,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6377:Clip1
|
UTSW |
5 |
123,741,717 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6436:Clip1
|
UTSW |
5 |
123,779,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6471:Clip1
|
UTSW |
5 |
123,778,612 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6766:Clip1
|
UTSW |
5 |
123,752,827 (GRCm39) |
unclassified |
probably benign |
|
|
R7015:Clip1
|
UTSW |
5 |
123,751,675 (GRCm39) |
unclassified |
probably benign |
|
|
R7094:Clip1
|
UTSW |
5 |
123,761,333 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7143:Clip1
|
UTSW |
5 |
123,791,673 (GRCm39) |
missense |
probably benign |
|
|
R7222:Clip1
|
UTSW |
5 |
123,749,904 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7233:Clip1
|
UTSW |
5 |
123,749,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Clip1
|
UTSW |
5 |
123,751,328 (GRCm39) |
missense |
|
|
|
R7249:Clip1
|
UTSW |
5 |
123,741,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7283:Clip1
|
UTSW |
5 |
123,751,857 (GRCm39) |
missense |
|
|
|
R7295:Clip1
|
UTSW |
5 |
123,765,419 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7447:Clip1
|
UTSW |
5 |
123,791,696 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7458:Clip1
|
UTSW |
5 |
123,778,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7483:Clip1
|
UTSW |
5 |
123,755,447 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7516:Clip1
|
UTSW |
5 |
123,721,448 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7619:Clip1
|
UTSW |
5 |
123,752,342 (GRCm39) |
missense |
|
|
|
R7897:Clip1
|
UTSW |
5 |
123,760,861 (GRCm39) |
missense |
probably benign |
|
|
R8155:Clip1
|
UTSW |
5 |
123,751,699 (GRCm39) |
missense |
|
|
|
R8157:Clip1
|
UTSW |
5 |
123,768,782 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8232:Clip1
|
UTSW |
5 |
123,785,981 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8396:Clip1
|
UTSW |
5 |
123,780,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8446:Clip1
|
UTSW |
5 |
123,794,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8486:Clip1
|
UTSW |
5 |
123,752,770 (GRCm39) |
unclassified |
probably benign |
|
|
R8511:Clip1
|
UTSW |
5 |
123,791,969 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8731:Clip1
|
UTSW |
5 |
123,752,756 (GRCm39) |
missense |
|
|
|
R8889:Clip1
|
UTSW |
5 |
123,717,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8892:Clip1
|
UTSW |
5 |
123,717,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9058:Clip1
|
UTSW |
5 |
123,752,645 (GRCm39) |
missense |
|
|
|
R9106:Clip1
|
UTSW |
5 |
123,753,223 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9212:Clip1
|
UTSW |
5 |
123,721,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9217:Clip1
|
UTSW |
5 |
123,717,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9223:Clip1
|
UTSW |
5 |
123,784,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9325:Clip1
|
UTSW |
5 |
123,751,186 (GRCm39) |
missense |
|
|
|
R9752:Clip1
|
UTSW |
5 |
123,760,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Clip1
|
UTSW |
5 |
123,755,413 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTGCTAAGTACTCGAACCTCTC -3'
(R):5'- GACCCTCAAAAGCGACTTCG -3'
Sequencing Primer
(F):5'- CGAATGAAGGGTCTCAAGCTCTC -3'
(R):5'- GCTGCCCTTTCCAAGTCCAAG -3'
|
| Posted On |
2019-12-20 |
Incidental Mutation