Incidental Mutation 'R8906:Mical2'
| ID |
680112 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mical2
|
| Ensembl Gene |
ENSMUSG00000038244 |
| Gene Name |
microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| Synonyms |
4921517J23Rik, Ebitein1, 5330438E18Rik, Micalcl |
| MMRRC Submission |
068699-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.298)
|
| Stock # |
R8906 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
111825063-112012313 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 111980671 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Asparagine
at position 105
(I105N)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000033033]
[ENSMUST00000051308]
[ENSMUST00000106645]
|
| AlphaFold |
Q8BML1
Q9D5U9 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000033033
AA Change: I281N
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000033033
Gene: ENSMUSG00000030771
AA Change: I281N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
18 |
N/A |
INTRINSIC |
|
low complexity region
|
72 |
100 |
N/A |
INTRINSIC |
|
low complexity region
|
393 |
404 |
N/A |
INTRINSIC |
|
low complexity region
|
415 |
432 |
N/A |
INTRINSIC |
|
low complexity region
|
545 |
562 |
N/A |
INTRINSIC |
|
coiled coil region
|
569 |
597 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000051308
AA Change: I215N
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000062443
Gene: ENSMUSG00000030771
AA Change: I215N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
34 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
338 |
N/A |
INTRINSIC |
|
low complexity region
|
349 |
366 |
N/A |
INTRINSIC |
|
low complexity region
|
479 |
496 |
N/A |
INTRINSIC |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
DUF3585
|
526 |
668 |
6.86e-56 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106645
AA Change: I215N
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000102256
Gene: ENSMUSG00000030771
AA Change: I215N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
34 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
338 |
N/A |
INTRINSIC |
|
low complexity region
|
349 |
366 |
N/A |
INTRINSIC |
|
low complexity region
|
479 |
496 |
N/A |
INTRINSIC |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
DUF3585
|
526 |
668 |
6.86e-56 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000213108
AA Change: I105N
PolyPhen 2
Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000215412
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000216652
AA Change: I427N
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.4%
|
| Validation Efficiency |
100% (88/88) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1810055G02Rik |
A |
C |
19: 3,766,686 (GRCm39) |
N91T |
possibly damaging |
Het |
| 2510009E07Rik |
CCGGAAGGGGAGGAGCAGTGACCCAGTTTCGGA |
CCGGA |
16: 21,472,148 (GRCm39) |
|
probably null |
Het |
| 4932414N04Rik |
A |
G |
2: 68,562,498 (GRCm39) |
D375G |
possibly damaging |
Het |
| Adad2 |
C |
A |
8: 120,339,725 (GRCm39) |
P69Q |
probably benign |
Het |
| Adamts3 |
G |
A |
5: 89,825,575 (GRCm39) |
T1088I |
probably damaging |
Het |
| Ank2 |
A |
G |
3: 126,726,720 (GRCm39) |
V858A |
probably benign |
Het |
| Ankrd13a |
A |
G |
5: 114,939,798 (GRCm39) |
N475S |
probably benign |
Het |
| Barhl2 |
G |
A |
5: 106,603,352 (GRCm39) |
T269I |
probably benign |
Het |
| Boc |
G |
A |
16: 44,323,931 (GRCm39) |
R157W |
|
Het |
| Bsn |
G |
T |
9: 107,984,752 (GRCm39) |
P3101T |
unknown |
Het |
| Catsperb |
C |
A |
12: 101,486,904 (GRCm39) |
A477E |
possibly damaging |
Het |
| Ccser1 |
T |
A |
6: 61,787,842 (GRCm39) |
I220K |
probably benign |
Het |
| Cd200r3 |
A |
T |
16: 44,778,102 (GRCm39) |
I242F |
possibly damaging |
Het |
| Cdc34b |
A |
C |
11: 94,632,911 (GRCm39) |
D37A |
probably damaging |
Het |
| Chek2 |
A |
G |
5: 111,013,458 (GRCm39) |
|
probably benign |
Het |
| Cngb1 |
A |
T |
8: 95,989,736 (GRCm39) |
V792D |
probably damaging |
Het |
| Cops7a |
T |
C |
6: 124,939,371 (GRCm39) |
K93E |
possibly damaging |
Het |
| Crispld1 |
T |
C |
1: 17,820,995 (GRCm39) |
I345T |
possibly damaging |
Het |
| Dgkd |
A |
G |
1: 87,869,157 (GRCm39) |
D1170G |
probably damaging |
Het |
| Dhx35 |
A |
G |
2: 158,648,918 (GRCm39) |
T115A |
possibly damaging |
Het |
| Dnai1 |
G |
A |
4: 41,625,125 (GRCm39) |
R363H |
probably benign |
Het |
| Dnmbp |
T |
A |
19: 43,878,681 (GRCm39) |
Q130L |
probably benign |
Het |
| Egfr |
A |
G |
11: 16,861,635 (GRCm39) |
Y1138C |
probably damaging |
Het |
| Elf3 |
A |
T |
1: 135,182,678 (GRCm39) |
L329Q |
probably damaging |
Het |
| Enkur |
A |
G |
2: 21,201,568 (GRCm39) |
M39T |
probably benign |
Het |
| Epha7 |
T |
C |
4: 28,821,615 (GRCm39) |
I260T |
probably damaging |
Het |
| Fbxo28 |
A |
T |
1: 182,144,634 (GRCm39) |
I310K |
probably damaging |
Het |
| Fga |
C |
A |
3: 82,939,111 (GRCm39) |
N495K |
probably benign |
Het |
| Galnt6 |
T |
C |
15: 100,601,247 (GRCm39) |
D344G |
probably damaging |
Het |
| Gm572 |
A |
G |
4: 148,751,290 (GRCm39) |
Q221R |
probably benign |
Het |
| Gpa33 |
G |
A |
1: 165,974,216 (GRCm39) |
A18T |
probably benign |
Het |
| Gpatch11 |
C |
T |
17: 79,145,289 (GRCm39) |
T6I |
probably benign |
Het |
| Gpr84 |
T |
A |
15: 103,217,625 (GRCm39) |
S151C |
probably damaging |
Het |
| H2-M11 |
T |
A |
17: 36,859,851 (GRCm39) |
Y281* |
probably null |
Het |
| Hadh |
T |
C |
3: 131,038,891 (GRCm39) |
N155S |
probably benign |
Het |
| Hoxd13 |
A |
G |
2: 74,500,266 (GRCm39) |
Y269C |
|
Het |
| Iars1 |
T |
A |
13: 49,882,177 (GRCm39) |
C1074S |
probably benign |
Het |
| Ibtk |
G |
T |
9: 85,625,457 (GRCm39) |
H98N |
possibly damaging |
Het |
| Igsf10 |
C |
T |
3: 59,233,739 (GRCm39) |
G1665R |
probably benign |
Het |
| Inpp5d |
A |
G |
1: 87,625,337 (GRCm39) |
|
probably benign |
Het |
| Ipo9 |
A |
C |
1: 135,321,951 (GRCm39) |
V593G |
probably damaging |
Het |
| Irx3 |
T |
C |
8: 92,526,915 (GRCm39) |
D263G |
possibly damaging |
Het |
| Kif13a |
A |
G |
13: 46,927,154 (GRCm39) |
V1179A |
probably benign |
Het |
| Lrrc4c |
T |
C |
2: 97,460,393 (GRCm39) |
Y340H |
probably benign |
Het |
| Lysmd1 |
A |
G |
3: 95,045,219 (GRCm39) |
D155G |
probably damaging |
Het |
| Mob2 |
A |
T |
7: 141,563,261 (GRCm39) |
L66Q |
probably damaging |
Het |
| Myh1 |
A |
G |
11: 67,096,739 (GRCm39) |
S337G |
probably benign |
Het |
| Neb |
T |
C |
2: 52,096,259 (GRCm39) |
D1002G |
probably benign |
Het |
| Nebl |
A |
T |
2: 17,382,928 (GRCm39) |
N116K |
probably benign |
Het |
| Nkx2-6 |
T |
C |
14: 69,412,623 (GRCm39) |
S264P |
probably benign |
Het |
| Nlgn3 |
T |
C |
X: 100,352,390 (GRCm39) |
V179A |
probably damaging |
Het |
| Nlrp4e |
A |
G |
7: 23,020,556 (GRCm39) |
T348A |
possibly damaging |
Het |
| Nomo1 |
A |
T |
7: 45,722,004 (GRCm39) |
I982F |
probably benign |
Het |
| Or10j5 |
A |
G |
1: 172,784,186 (GRCm39) |
|
probably benign |
Het |
| Or11g24 |
T |
G |
14: 50,662,291 (GRCm39) |
F105C |
probably damaging |
Het |
| Or1j19 |
A |
T |
2: 36,676,621 (GRCm39) |
Y28F |
probably benign |
Het |
| Or8g22 |
A |
G |
9: 38,958,077 (GRCm39) |
F213L |
possibly damaging |
Het |
| Palld |
A |
G |
8: 62,003,198 (GRCm39) |
|
probably null |
Het |
| Pcdh7 |
A |
G |
5: 57,879,154 (GRCm39) |
Y903C |
probably damaging |
Het |
| Pknox2 |
G |
A |
9: 36,804,167 (GRCm39) |
T460M |
possibly damaging |
Het |
| Ppm1h |
C |
T |
10: 122,714,451 (GRCm39) |
T330I |
probably damaging |
Het |
| Ppp2r2b |
C |
T |
18: 42,821,399 (GRCm39) |
R253H |
probably damaging |
Het |
| Pramel58 |
G |
T |
5: 94,831,413 (GRCm39) |
R140L |
possibly damaging |
Het |
| Prr18 |
G |
A |
17: 8,560,476 (GRCm39) |
A211T |
probably benign |
Het |
| Ptgs2 |
A |
G |
1: 149,979,859 (GRCm39) |
I321M |
|
Het |
| Rara |
G |
T |
11: 98,860,989 (GRCm39) |
R159L |
probably damaging |
Het |
| Rasa4 |
T |
A |
5: 136,133,446 (GRCm39) |
I635N |
probably benign |
Het |
| Rxfp2 |
A |
T |
5: 149,989,888 (GRCm39) |
H423L |
possibly damaging |
Het |
| Scn4b |
A |
G |
9: 45,059,169 (GRCm39) |
I147V |
possibly damaging |
Het |
| Scrn3 |
G |
A |
2: 73,161,352 (GRCm39) |
V313I |
probably benign |
Het |
| Scrn3 |
C |
A |
2: 73,161,355 (GRCm39) |
P314T |
possibly damaging |
Het |
| Sh2b1 |
A |
G |
7: 126,070,292 (GRCm39) |
|
probably null |
Het |
| Slc26a10 |
T |
C |
10: 127,016,459 (GRCm39) |
Q3R |
probably benign |
Het |
| Slitrk1 |
A |
G |
14: 109,149,139 (GRCm39) |
I524T |
probably damaging |
Het |
| Smcp |
T |
A |
3: 92,491,530 (GRCm39) |
N106Y |
unknown |
Het |
| Spata31h1 |
T |
C |
10: 82,122,379 (GRCm39) |
T3544A |
probably benign |
Het |
| St8sia5 |
G |
A |
18: 77,336,172 (GRCm39) |
V202M |
probably damaging |
Het |
| Stxbp5l |
A |
T |
16: 37,028,526 (GRCm39) |
D512E |
probably damaging |
Het |
| Tas1r2 |
A |
G |
4: 139,397,046 (GRCm39) |
E795G |
probably damaging |
Het |
| Tdrd1 |
T |
A |
19: 56,831,145 (GRCm39) |
V320D |
probably damaging |
Het |
| Tmem71 |
T |
A |
15: 66,404,606 (GRCm39) |
I261L |
probably benign |
Het |
| Tns2 |
T |
C |
15: 102,020,039 (GRCm39) |
L643P |
probably damaging |
Het |
| Upf1 |
G |
A |
8: 70,786,815 (GRCm39) |
Q890* |
probably null |
Het |
| Usp43 |
A |
T |
11: 67,782,307 (GRCm39) |
H370Q |
possibly damaging |
Het |
| Vmn1r236 |
T |
A |
17: 21,507,356 (GRCm39) |
I158N |
possibly damaging |
Het |
| Vmn2r98 |
T |
A |
17: 19,286,532 (GRCm39) |
N343K |
probably benign |
Het |
| Vwa8 |
T |
C |
14: 79,329,815 (GRCm39) |
S1216P |
probably benign |
Het |
| Yars1 |
A |
C |
4: 129,090,747 (GRCm39) |
D97A |
probably damaging |
Het |
| Zer1 |
G |
A |
2: 30,001,035 (GRCm39) |
H129Y |
probably benign |
Het |
| Zfat |
C |
T |
15: 67,956,404 (GRCm39) |
D1143N |
possibly damaging |
Het |
|
| Other mutations in Mical2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Mical2
|
APN |
7 |
111,981,352 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00886:Mical2
|
APN |
7 |
111,914,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00934:Mical2
|
APN |
7 |
111,948,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00941:Mical2
|
APN |
7 |
111,920,652 (GRCm39) |
splice site |
probably benign |
|
|
IGL01020:Mical2
|
APN |
7 |
111,914,283 (GRCm39) |
splice site |
probably benign |
|
|
IGL01395:Mical2
|
APN |
7 |
111,922,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01658:Mical2
|
APN |
7 |
111,914,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01775:Mical2
|
APN |
7 |
111,981,269 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02040:Mical2
|
APN |
7 |
111,910,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02051:Mical2
|
APN |
7 |
111,980,597 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02388:Mical2
|
APN |
7 |
111,934,620 (GRCm39) |
missense |
probably benign |
|
|
IGL02551:Mical2
|
APN |
7 |
111,923,197 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02578:Mical2
|
APN |
7 |
111,950,580 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02751:Mical2
|
APN |
7 |
111,931,243 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL03114:Mical2
|
APN |
7 |
111,996,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0091:Mical2
|
UTSW |
7 |
111,980,503 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0101:Mical2
|
UTSW |
7 |
111,936,074 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0415:Mical2
|
UTSW |
7 |
111,980,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0504:Mical2
|
UTSW |
7 |
111,870,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0594:Mical2
|
UTSW |
7 |
111,917,657 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0609:Mical2
|
UTSW |
7 |
111,920,647 (GRCm39) |
splice site |
probably null |
|
|
R0962:Mical2
|
UTSW |
7 |
111,979,624 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1521:Mical2
|
UTSW |
7 |
111,980,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1542:Mical2
|
UTSW |
7 |
111,908,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1611:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1740:Mical2
|
UTSW |
7 |
111,933,043 (GRCm39) |
missense |
probably benign |
|
|
R1815:Mical2
|
UTSW |
7 |
112,012,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1855:Mical2
|
UTSW |
7 |
111,944,489 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1958:Mical2
|
UTSW |
7 |
111,980,311 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1962:Mical2
|
UTSW |
7 |
112,012,051 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2086:Mical2
|
UTSW |
7 |
111,917,810 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2136:Mical2
|
UTSW |
7 |
111,870,722 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2418:Mical2
|
UTSW |
7 |
111,919,941 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2439:Mical2
|
UTSW |
7 |
111,994,002 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3053:Mical2
|
UTSW |
7 |
111,910,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3979:Mical2
|
UTSW |
7 |
112,006,885 (GRCm39) |
splice site |
probably null |
|
|
R4308:Mical2
|
UTSW |
7 |
111,931,199 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4551:Mical2
|
UTSW |
7 |
111,981,123 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4583:Mical2
|
UTSW |
7 |
112,012,154 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4663:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4868:Mical2
|
UTSW |
7 |
111,917,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Mical2
|
UTSW |
7 |
111,936,107 (GRCm39) |
missense |
probably benign |
|
|
R5112:Mical2
|
UTSW |
7 |
111,919,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5459:Mical2
|
UTSW |
7 |
111,981,444 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5487:Mical2
|
UTSW |
7 |
111,919,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5563:Mical2
|
UTSW |
7 |
111,914,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5763:Mical2
|
UTSW |
7 |
111,973,861 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5817:Mical2
|
UTSW |
7 |
111,922,866 (GRCm39) |
missense |
probably benign |
|
|
R5987:Mical2
|
UTSW |
7 |
111,934,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6042:Mical2
|
UTSW |
7 |
111,979,619 (GRCm39) |
missense |
probably benign |
0.40 |
|
R6087:Mical2
|
UTSW |
7 |
111,917,692 (GRCm39) |
nonsense |
probably null |
|
|
R6189:Mical2
|
UTSW |
7 |
112,012,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Mical2
|
UTSW |
7 |
111,923,293 (GRCm39) |
splice site |
probably null |
|
|
R6311:Mical2
|
UTSW |
7 |
111,922,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6319:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6578:Mical2
|
UTSW |
7 |
111,910,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6750:Mical2
|
UTSW |
7 |
111,981,046 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6782:Mical2
|
UTSW |
7 |
111,945,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6798:Mical2
|
UTSW |
7 |
111,975,266 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R7061:Mical2
|
UTSW |
7 |
111,946,008 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7147:Mical2
|
UTSW |
7 |
111,922,810 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7260:Mical2
|
UTSW |
7 |
111,919,001 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7266:Mical2
|
UTSW |
7 |
111,902,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7347:Mical2
|
UTSW |
7 |
111,981,358 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7391:Mical2
|
UTSW |
7 |
111,919,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7747:Mical2
|
UTSW |
7 |
111,933,046 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7783:Mical2
|
UTSW |
7 |
112,012,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7818:Mical2
|
UTSW |
7 |
111,944,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7824:Mical2
|
UTSW |
7 |
112,006,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Mical2
|
UTSW |
7 |
111,980,975 (GRCm39) |
missense |
probably benign |
0.31 |
|
R8022:Mical2
|
UTSW |
7 |
111,902,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8429:Mical2
|
UTSW |
7 |
111,944,460 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8505:Mical2
|
UTSW |
7 |
111,919,007 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8532:Mical2
|
UTSW |
7 |
111,917,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8830:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8862:Mical2
|
UTSW |
7 |
111,910,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8988:Mical2
|
UTSW |
7 |
111,910,661 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9006:Mical2
|
UTSW |
7 |
111,981,323 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9123:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9127:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9128:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9129:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9140:Mical2
|
UTSW |
7 |
112,006,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9187:Mical2
|
UTSW |
7 |
111,902,797 (GRCm39) |
nonsense |
probably null |
|
|
R9233:Mical2
|
UTSW |
7 |
111,981,399 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9304:Mical2
|
UTSW |
7 |
111,980,974 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9310:Mical2
|
UTSW |
7 |
111,950,920 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9377:Mical2
|
UTSW |
7 |
111,981,246 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9399:Mical2
|
UTSW |
7 |
111,946,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Mical2
|
UTSW |
7 |
112,010,665 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9500:Mical2
|
UTSW |
7 |
111,936,054 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9620:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9652:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Mical2
|
UTSW |
7 |
111,921,806 (GRCm39) |
missense |
probably benign |
0.37 |
|
R9756:Mical2
|
UTSW |
7 |
111,902,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9789:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF008:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0062:Mical2
|
UTSW |
7 |
111,946,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAACCTAGCTCTTGGTGCTG -3'
(R):5'- GAGACCTAAGGATGGCATTTGC -3'
Sequencing Primer
(F):5'- CTCTTGGTGCTGCAGGGAAC -3'
(R):5'- ACCTAAGGATGGCATTTGCTATGAG -3'
|
| Posted On |
2021-08-31 |
Incidental Mutation