Incidental Mutation 'R9652:Mical2'
| ID |
735381 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mical2
|
| Ensembl Gene |
ENSMUSG00000038244 |
| Gene Name |
microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| Synonyms |
4921517J23Rik, Ebitein1, 5330438E18Rik, Micalcl |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.298)
|
| Stock # |
R9652 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
111825063-112012313 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 111945996 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Leucine
at position 986
(R986L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000047639
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037991]
[ENSMUST00000050149]
|
| AlphaFold |
Q8BML1
Q9D5U9 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000037991
AA Change: R986L
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000047639
Gene: ENSMUSG00000038244
AA Change: R986L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:FAD_binding_3
|
86 |
143 |
1e-8 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
3.2e-6 |
PFAM |
|
low complexity region
|
175 |
188 |
N/A |
INTRINSIC |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
CH
|
518 |
617 |
4.14e-17 |
SMART |
|
low complexity region
|
691 |
700 |
N/A |
INTRINSIC |
|
low complexity region
|
894 |
925 |
N/A |
INTRINSIC |
|
LIM
|
979 |
1033 |
9.91e-10 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000050149
AA Change: R759L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000051163
Gene: ENSMUSG00000038244
AA Change: R759L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:FAD_binding_3
|
86 |
143 |
1.1e-8 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
1.5e-6 |
PFAM |
|
Pfam:Pyr_redox_2
|
88 |
259 |
1.3e-6 |
PFAM |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
CH
|
518 |
617 |
4.14e-17 |
SMART |
|
low complexity region
|
691 |
700 |
N/A |
INTRINSIC |
|
LIM
|
752 |
806 |
9.91e-10 |
SMART |
|
low complexity region
|
918 |
926 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000123341
Gene: ENSMUSG00000038244
AA Change: R20L
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
14 |
68 |
9.91e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000215412
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000216652
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.8%
- 10x: 99.6%
- 20x: 99.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Afap1l1 |
G |
A |
18: 61,876,432 (GRCm39) |
T395M |
probably damaging |
Het |
| Akap8l |
T |
C |
17: 32,557,783 (GRCm39) |
N35D |
probably damaging |
Het |
| Atr |
T |
A |
9: 95,756,887 (GRCm39) |
L922Q |
probably damaging |
Het |
| B3gnt9 |
G |
T |
8: 105,981,129 (GRCm39) |
F86L |
probably damaging |
Het |
| Bmp1 |
T |
C |
14: 70,715,360 (GRCm39) |
D925G |
probably damaging |
Het |
| Camkmt |
A |
T |
17: 85,759,713 (GRCm39) |
R284S |
probably benign |
Het |
| Cavin3 |
G |
T |
7: 105,131,304 (GRCm39) |
H21Q |
probably damaging |
Het |
| Ccp110 |
A |
G |
7: 118,334,553 (GRCm39) |
H180R |
|
Het |
| Cdh23 |
A |
T |
10: 60,167,135 (GRCm39) |
V1837E |
probably damaging |
Het |
| Ces3b |
G |
T |
8: 105,812,257 (GRCm39) |
A169S |
probably damaging |
Het |
| Chpt1 |
T |
C |
10: 88,325,499 (GRCm39) |
N122S |
probably benign |
Het |
| Cramp1 |
C |
A |
17: 25,201,783 (GRCm39) |
K566N |
probably damaging |
Het |
| Ctbp2 |
C |
G |
7: 132,615,933 (GRCm39) |
R334P |
probably damaging |
Het |
| Cwh43 |
T |
C |
5: 73,572,340 (GRCm39) |
S193P |
probably benign |
Het |
| Dcstamp |
A |
T |
15: 39,623,792 (GRCm39) |
D469V |
probably benign |
Het |
| Dst |
T |
A |
1: 34,219,458 (GRCm39) |
I1966N |
probably benign |
Het |
| Eif3i |
G |
T |
4: 129,489,094 (GRCm39) |
F121L |
probably benign |
Het |
| Erbb2 |
T |
C |
11: 98,326,812 (GRCm39) |
S1074P |
probably damaging |
Het |
| Fam186b |
G |
A |
15: 99,177,616 (GRCm39) |
A570V |
probably damaging |
Het |
| Fbn2 |
A |
G |
18: 58,146,722 (GRCm39) |
|
probably null |
Het |
| Foxo3 |
C |
T |
10: 42,073,021 (GRCm39) |
V499M |
probably damaging |
Het |
| Gm2a |
T |
C |
11: 54,999,764 (GRCm39) |
V95A |
probably benign |
Het |
| Gp5 |
A |
C |
16: 30,128,393 (GRCm39) |
F94V |
probably damaging |
Het |
| Gramd4 |
G |
A |
15: 86,016,160 (GRCm39) |
E504K |
probably damaging |
Het |
| Gusb |
A |
G |
5: 130,026,652 (GRCm39) |
S450P |
probably damaging |
Het |
| Htr5a |
A |
G |
5: 28,047,838 (GRCm39) |
N131S |
possibly damaging |
Het |
| Itga2 |
G |
A |
13: 115,020,991 (GRCm39) |
P120L |
probably benign |
Het |
| Itpkb |
G |
T |
1: 180,160,056 (GRCm39) |
E61* |
probably null |
Het |
| Katnbl1 |
T |
A |
2: 112,239,497 (GRCm39) |
V232D |
probably damaging |
Het |
| Kifap3 |
T |
C |
1: 163,689,657 (GRCm39) |
L547P |
probably damaging |
Het |
| Krt6a |
C |
T |
15: 101,599,120 (GRCm39) |
V482M |
probably benign |
Het |
| Lrfn5 |
T |
A |
12: 61,890,418 (GRCm39) |
V569D |
probably damaging |
Het |
| Luzp2 |
A |
G |
7: 54,702,580 (GRCm39) |
T48A |
probably damaging |
Het |
| Mroh8 |
G |
A |
2: 157,094,970 (GRCm39) |
Q339* |
probably null |
Het |
| Msln |
A |
T |
17: 25,968,042 (GRCm39) |
V541E |
probably damaging |
Het |
| Muc16 |
T |
A |
9: 18,498,178 (GRCm39) |
M6590L |
probably benign |
Het |
| Nhsl3 |
T |
C |
4: 129,117,962 (GRCm39) |
E279G |
possibly damaging |
Het |
| Nisch |
A |
T |
14: 30,893,628 (GRCm39) |
V1315E |
probably damaging |
Het |
| Nubp2 |
G |
A |
17: 25,103,382 (GRCm39) |
T165I |
probably damaging |
Het |
| Oog3 |
T |
G |
4: 143,884,489 (GRCm39) |
R482S |
probably benign |
Het |
| Or2a7 |
A |
G |
6: 43,150,991 (GRCm39) |
M24V |
probably benign |
Het |
| Or56a42-ps1 |
A |
T |
7: 104,775,985 (GRCm39) |
N164K |
probably benign |
Het |
| Or6c33 |
T |
C |
10: 129,853,809 (GRCm39) |
I193T |
possibly damaging |
Het |
| Or7a41 |
T |
C |
10: 78,871,230 (GRCm39) |
I200T |
probably benign |
Het |
| Or8k39 |
A |
T |
2: 86,563,636 (GRCm39) |
F107I |
probably damaging |
Het |
| P3h4 |
A |
T |
11: 100,304,499 (GRCm39) |
C247* |
probably null |
Het |
| Pakap |
G |
A |
4: 57,710,125 (GRCm39) |
A357T |
possibly damaging |
Het |
| Plch2 |
T |
A |
4: 155,082,942 (GRCm39) |
M569L |
probably benign |
Het |
| Plcl1 |
A |
G |
1: 55,735,450 (GRCm39) |
T264A |
probably benign |
Het |
| Rad51ap1 |
G |
T |
6: 126,904,526 (GRCm39) |
N178K |
probably benign |
Het |
| Rasa4 |
T |
C |
5: 136,130,494 (GRCm39) |
L340P |
probably damaging |
Het |
| Rassf10 |
A |
G |
7: 112,554,784 (GRCm39) |
T462A |
probably benign |
Het |
| Rlf |
G |
C |
4: 121,007,865 (GRCm39) |
L482V |
probably damaging |
Het |
| Robo1 |
T |
G |
16: 72,821,330 (GRCm39) |
S1357A |
possibly damaging |
Het |
| Rp1l1 |
T |
C |
14: 64,269,714 (GRCm39) |
S1767P |
probably damaging |
Het |
| Rpl3l |
T |
A |
17: 24,947,328 (GRCm39) |
L14Q |
probably damaging |
Het |
| Ryr3 |
T |
A |
2: 112,635,047 (GRCm39) |
T2024S |
possibly damaging |
Het |
| Sbf2 |
T |
C |
7: 110,040,702 (GRCm39) |
Q375R |
possibly damaging |
Het |
| Sema6a |
T |
C |
18: 47,382,252 (GRCm39) |
Q765R |
probably damaging |
Het |
| Senp6 |
T |
A |
9: 80,021,228 (GRCm39) |
Y303N |
probably damaging |
Het |
| Sertad4 |
C |
T |
1: 192,528,836 (GRCm39) |
D327N |
probably damaging |
Het |
| Slc22a15 |
T |
A |
3: 101,790,848 (GRCm39) |
Y219F |
possibly damaging |
Het |
| Slco1b2 |
T |
G |
6: 141,594,358 (GRCm39) |
|
probably null |
Het |
| Snrnp200 |
G |
T |
2: 127,067,959 (GRCm39) |
V819L |
probably damaging |
Het |
| Ssb |
C |
A |
2: 69,700,784 (GRCm39) |
A288E |
probably damaging |
Het |
| Syne2 |
A |
G |
12: 76,101,620 (GRCm39) |
H638R |
probably benign |
Het |
| Tm7sf3 |
A |
G |
6: 146,527,698 (GRCm39) |
S43P |
probably benign |
Het |
| Tmem200c |
A |
G |
17: 69,149,181 (GRCm39) |
H588R |
probably benign |
Het |
| Tnpo3 |
G |
A |
6: 29,560,173 (GRCm39) |
R657* |
probably null |
Het |
| Traf6 |
T |
C |
2: 101,518,927 (GRCm39) |
C139R |
probably damaging |
Het |
| Txnrd1 |
C |
A |
10: 82,720,390 (GRCm39) |
N424K |
possibly damaging |
Het |
| Ubqln3 |
T |
C |
7: 103,791,962 (GRCm39) |
I43V |
probably damaging |
Het |
| Usp32 |
A |
G |
11: 84,921,317 (GRCm39) |
V699A |
probably damaging |
Het |
| Vmn2r103 |
T |
C |
17: 20,014,027 (GRCm39) |
V273A |
probably benign |
Het |
| Vmn2r8 |
A |
G |
5: 108,951,107 (GRCm39) |
S113P |
probably benign |
Het |
| Wdr7 |
T |
A |
18: 63,860,826 (GRCm39) |
I161N |
probably damaging |
Het |
| Zfp474 |
A |
T |
18: 52,772,015 (GRCm39) |
I223F |
probably damaging |
Het |
| Zfp583 |
A |
G |
7: 6,320,328 (GRCm39) |
L228P |
probably damaging |
Het |
| Zfyve27 |
A |
G |
19: 42,165,856 (GRCm39) |
T76A |
possibly damaging |
Het |
|
| Other mutations in Mical2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Mical2
|
APN |
7 |
111,981,352 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00886:Mical2
|
APN |
7 |
111,914,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00934:Mical2
|
APN |
7 |
111,948,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00941:Mical2
|
APN |
7 |
111,920,652 (GRCm39) |
splice site |
probably benign |
|
|
IGL01020:Mical2
|
APN |
7 |
111,914,283 (GRCm39) |
splice site |
probably benign |
|
|
IGL01395:Mical2
|
APN |
7 |
111,922,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01658:Mical2
|
APN |
7 |
111,914,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01775:Mical2
|
APN |
7 |
111,981,269 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02040:Mical2
|
APN |
7 |
111,910,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02051:Mical2
|
APN |
7 |
111,980,597 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02388:Mical2
|
APN |
7 |
111,934,620 (GRCm39) |
missense |
probably benign |
|
|
IGL02551:Mical2
|
APN |
7 |
111,923,197 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02578:Mical2
|
APN |
7 |
111,950,580 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02751:Mical2
|
APN |
7 |
111,931,243 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL03114:Mical2
|
APN |
7 |
111,996,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0091:Mical2
|
UTSW |
7 |
111,980,503 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0101:Mical2
|
UTSW |
7 |
111,936,074 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0415:Mical2
|
UTSW |
7 |
111,980,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0504:Mical2
|
UTSW |
7 |
111,870,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0594:Mical2
|
UTSW |
7 |
111,917,657 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0609:Mical2
|
UTSW |
7 |
111,920,647 (GRCm39) |
splice site |
probably null |
|
|
R0962:Mical2
|
UTSW |
7 |
111,979,624 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1521:Mical2
|
UTSW |
7 |
111,980,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1542:Mical2
|
UTSW |
7 |
111,908,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1611:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1740:Mical2
|
UTSW |
7 |
111,933,043 (GRCm39) |
missense |
probably benign |
|
|
R1815:Mical2
|
UTSW |
7 |
112,012,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1855:Mical2
|
UTSW |
7 |
111,944,489 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1958:Mical2
|
UTSW |
7 |
111,980,311 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1962:Mical2
|
UTSW |
7 |
112,012,051 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2086:Mical2
|
UTSW |
7 |
111,917,810 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2136:Mical2
|
UTSW |
7 |
111,870,722 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2418:Mical2
|
UTSW |
7 |
111,919,941 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2439:Mical2
|
UTSW |
7 |
111,994,002 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3053:Mical2
|
UTSW |
7 |
111,910,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3979:Mical2
|
UTSW |
7 |
112,006,885 (GRCm39) |
splice site |
probably null |
|
|
R4308:Mical2
|
UTSW |
7 |
111,931,199 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4551:Mical2
|
UTSW |
7 |
111,981,123 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4583:Mical2
|
UTSW |
7 |
112,012,154 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4663:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4868:Mical2
|
UTSW |
7 |
111,917,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Mical2
|
UTSW |
7 |
111,936,107 (GRCm39) |
missense |
probably benign |
|
|
R5112:Mical2
|
UTSW |
7 |
111,919,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5459:Mical2
|
UTSW |
7 |
111,981,444 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5487:Mical2
|
UTSW |
7 |
111,919,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5563:Mical2
|
UTSW |
7 |
111,914,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5763:Mical2
|
UTSW |
7 |
111,973,861 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5817:Mical2
|
UTSW |
7 |
111,922,866 (GRCm39) |
missense |
probably benign |
|
|
R5987:Mical2
|
UTSW |
7 |
111,934,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6042:Mical2
|
UTSW |
7 |
111,979,619 (GRCm39) |
missense |
probably benign |
0.40 |
|
R6087:Mical2
|
UTSW |
7 |
111,917,692 (GRCm39) |
nonsense |
probably null |
|
|
R6189:Mical2
|
UTSW |
7 |
112,012,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Mical2
|
UTSW |
7 |
111,923,293 (GRCm39) |
splice site |
probably null |
|
|
R6311:Mical2
|
UTSW |
7 |
111,922,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6319:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6578:Mical2
|
UTSW |
7 |
111,910,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6750:Mical2
|
UTSW |
7 |
111,981,046 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6782:Mical2
|
UTSW |
7 |
111,945,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6798:Mical2
|
UTSW |
7 |
111,975,266 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R7061:Mical2
|
UTSW |
7 |
111,946,008 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7147:Mical2
|
UTSW |
7 |
111,922,810 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7260:Mical2
|
UTSW |
7 |
111,919,001 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7266:Mical2
|
UTSW |
7 |
111,902,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7347:Mical2
|
UTSW |
7 |
111,981,358 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7391:Mical2
|
UTSW |
7 |
111,919,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7747:Mical2
|
UTSW |
7 |
111,933,046 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7783:Mical2
|
UTSW |
7 |
112,012,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7818:Mical2
|
UTSW |
7 |
111,944,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7824:Mical2
|
UTSW |
7 |
112,006,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Mical2
|
UTSW |
7 |
111,980,975 (GRCm39) |
missense |
probably benign |
0.31 |
|
R8022:Mical2
|
UTSW |
7 |
111,902,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8429:Mical2
|
UTSW |
7 |
111,944,460 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8505:Mical2
|
UTSW |
7 |
111,919,007 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8532:Mical2
|
UTSW |
7 |
111,917,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8830:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8862:Mical2
|
UTSW |
7 |
111,910,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8988:Mical2
|
UTSW |
7 |
111,910,661 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9006:Mical2
|
UTSW |
7 |
111,981,323 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9123:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9127:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9128:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9129:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9140:Mical2
|
UTSW |
7 |
112,006,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9187:Mical2
|
UTSW |
7 |
111,902,797 (GRCm39) |
nonsense |
probably null |
|
|
R9233:Mical2
|
UTSW |
7 |
111,981,399 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9304:Mical2
|
UTSW |
7 |
111,980,974 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9310:Mical2
|
UTSW |
7 |
111,950,920 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9377:Mical2
|
UTSW |
7 |
111,981,246 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9399:Mical2
|
UTSW |
7 |
111,946,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Mical2
|
UTSW |
7 |
112,010,665 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9500:Mical2
|
UTSW |
7 |
111,936,054 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9620:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9657:Mical2
|
UTSW |
7 |
111,921,806 (GRCm39) |
missense |
probably benign |
0.37 |
|
R9756:Mical2
|
UTSW |
7 |
111,902,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9789:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF008:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0062:Mical2
|
UTSW |
7 |
111,946,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATAAGCTGCAGCCAAGAGCC -3'
(R):5'- TCCCTAAGCACTGTTCCTGATG -3'
Sequencing Primer
(F):5'- AAGAGCCCAGAAGTCCCTGTG -3'
(R):5'- ATCATACTCCCTGTTGGTAAGTG -3'
|
| Posted On |
2022-11-14 |
Incidental Mutation