Mutagenetix > Incidental Mutation

Incidental Mutation 'R4610:Fry'

344597

Institutional Source

Beutler Lab

Gene Symbol

Fry

Ensembl Gene

ENSMUSG00000056602

Gene Name

FRY microtubule binding protein

Synonyms

cg003, 9330186A19Rik

MMRRC Submission

041821-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.460) question?

Stock #

R4610 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

150042110-150421218 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 150309569 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Proline at position 671 (L671P)

Ref Sequence

ENSEMBL: ENSMUSP00000084454 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000087204]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000087204
AA Change: L671P

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000084454
Gene: ENSMUSG00000056602
AA Change: L671P

Domain	Start	End	E-Value	Type
Pfam:MOR2-PAG1_N	165	697	5.3e-170	PFAM
low complexity region	1014	1040	N/A	INTRINSIC
Pfam:MOR2-PAG1_mid	1188	1380	1.2e-15	PFAM
Pfam:MOR2-PAG1_mid	1398	1534	1.5e-5	PFAM
Pfam:MOR2-PAG1_mid	1632	1704	1.8e-7	PFAM
Pfam:MOR2-PAG1_mid	1772	1906	4.9e-10	PFAM
low complexity region	1936	1956	N/A	INTRINSIC
low complexity region	1962	1980	N/A	INTRINSIC
Pfam:MOR2-PAG1_C	2050	2303	1.9e-74	PFAM
low complexity region	2369	2385	N/A	INTRINSIC
low complexity region	2463	2482	N/A	INTRINSIC
low complexity region	2525	2534	N/A	INTRINSIC
low complexity region	2836	2852	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000202841

Meta Mutation Damage Score

0.4104

Coding Region Coverage

1x: 99.3%
3x: 98.7%
10x: 97.4%
20x: 95.5%

Validation Efficiency

98% (121/124)

Allele List at MGI

Other mutations in this stock

Total: 117 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aars2	T	A	17: 45,827,847 (GRCm39)	D555E	probably damaging	Het
Adgre1	C	A	17: 57,757,073 (GRCm39)	Q777K	possibly damaging	Het
Agpat4	G	A	17: 12,429,264 (GRCm39)		probably null	Het
Ak7	G	A	12: 105,679,834 (GRCm39)	V123M	probably benign	Het
Ankle1	AT	A	8: 71,859,851 (GRCm39)		probably benign	Het
Ankrd44	T	G	1: 54,805,907 (GRCm39)		probably benign	Het
Aprt	A	T	8: 123,302,154 (GRCm39)		probably null	Het
Aptx	T	C	4: 40,702,766 (GRCm39)		probably null	Het
Arsi	G	A	18: 61,049,723 (GRCm39)	G202E	probably benign	Het
AY358078	T	A	14: 52,063,532 (GRCm39)	C393S	possibly damaging	Het
Bbip1	T	C	19: 53,920,606 (GRCm39)	M1V	probably null	Het
Cacng7	T	A	7: 3,385,207 (GRCm39)	M36K	probably benign	Het
Camta1	A	G	4: 151,169,284 (GRCm39)	W156R	probably damaging	Het
Casd1	G	A	6: 4,631,165 (GRCm39)		probably null	Het
Casz1	T	A	4: 149,017,724 (GRCm39)	Y338N	probably damaging	Het
Ccdc66	T	C	14: 27,222,377 (GRCm39)	N122S	probably damaging	Het
Celf2	G	T	2: 6,590,831 (GRCm39)	N279K	possibly damaging	Het
Cfap96	A	T	8: 46,423,505 (GRCm39)	I69N	probably damaging	Het
Cit	A	G	5: 116,132,146 (GRCm39)	T1801A	probably benign	Het
Cnot2	A	G	10: 116,335,323 (GRCm39)	I275T	probably damaging	Het
Ddx4	T	C	13: 112,748,594 (GRCm39)	K435E	probably damaging	Het
Dnajc6	T	C	4: 101,468,461 (GRCm39)	F166L	probably damaging	Het
Dst	T	C	1: 34,208,937 (GRCm39)	L820P	probably damaging	Het
Dusp11	T	A	6: 85,927,037 (GRCm39)	N193Y	probably damaging	Het
Eif1ad7	T	C	12: 88,238,544 (GRCm39)	N72S	probably benign	Het
Eif3m	A	T	2: 104,843,633 (GRCm39)	N116K	probably benign	Het
Epb41l1	A	T	2: 156,351,181 (GRCm39)	E418D	possibly damaging	Het
Esyt2	T	G	12: 116,282,510 (GRCm39)	N153K	probably damaging	Het
Exoc6b	T	G	6: 84,980,141 (GRCm39)		probably benign	Het
Ezr	C	T	17: 7,007,121 (GRCm39)	E502K	possibly damaging	Het
Fbxw11	T	A	11: 32,661,859 (GRCm39)	Y66N	possibly damaging	Het
Frem2	A	G	3: 53,455,228 (GRCm39)	L2116S	possibly damaging	Het
Galnt7	A	G	8: 57,998,803 (GRCm39)	I262T	probably damaging	Het
Glp1r	T	C	17: 31,150,221 (GRCm39)	F381S	probably benign	Het
Gm3867	T	C	9: 36,168,567 (GRCm39)		noncoding transcript	Het
Gm8741	G	T	17: 35,555,062 (GRCm39)		noncoding transcript	Het
Golgb1	A	G	16: 36,738,987 (GRCm39)	D2442G	probably damaging	Het
Gp1bb	A	T	16: 18,439,893 (GRCm39)	L67Q	probably damaging	Het
Gstm7	G	A	3: 107,834,235 (GRCm39)	T206I	possibly damaging	Het
H2bc7	A	T	13: 23,758,231 (GRCm39)	V45E	possibly damaging	Het
Hs3st5	A	T	10: 36,704,802 (GRCm39)	D35V	probably benign	Het
Hspa13	T	C	16: 75,558,190 (GRCm39)	H125R	probably benign	Het
Hspa1a	T	G	17: 35,190,156 (GRCm39)	H249P	probably damaging	Het
Igkv10-95	A	T	6: 68,657,562 (GRCm39)	Q6L	probably damaging	Het
Il1rap	T	A	16: 26,533,526 (GRCm39)	L474H	probably benign	Het
Ipo11	T	A	13: 107,016,245 (GRCm39)	Y489F	probably benign	Het
Itga5	A	G	15: 103,259,259 (GRCm39)	Y723H	probably damaging	Het
Itih2	T	C	2: 10,109,971 (GRCm39)	N594S	probably damaging	Het
Itk	T	A	11: 46,227,342 (GRCm39)	Q427L	probably benign	Het
Kif26b	A	G	1: 178,506,920 (GRCm39)	Y332C	probably damaging	Het
Kmt2c	G	A	5: 25,559,382 (GRCm39)	R1086W	probably damaging	Het
Ktn1	T	A	14: 47,963,636 (GRCm39)		probably benign	Het
Lars2	T	A	9: 123,247,758 (GRCm39)	I305N	probably damaging	Het
Lgmn	G	T	12: 102,366,383 (GRCm39)		probably benign	Het
Ltbp4	C	T	7: 27,006,125 (GRCm39)	E1453K	probably damaging	Het
Lypd8	G	A	11: 58,277,675 (GRCm39)	M152I	probably benign	Het
Man2a1	T	A	17: 65,019,454 (GRCm39)	S773T	probably benign	Het
Map2k6	T	G	11: 110,390,300 (GRCm39)	L278R	probably damaging	Het
Mbtps1	A	T	8: 120,262,086 (GRCm39)	D354E	probably damaging	Het
Mcpt9	C	T	14: 56,266,049 (GRCm39)	V60M	probably damaging	Het
Mical3	C	A	6: 120,911,799 (GRCm39)	E1083*	probably null	Het
Mms19	A	G	19: 41,933,935 (GRCm39)	V811A	possibly damaging	Het
Mrc2	G	A	11: 105,239,257 (GRCm39)		probably null	Het
Mslnl	G	A	17: 25,961,908 (GRCm39)	V128M	probably damaging	Het
Mtcl1	T	A	17: 66,684,882 (GRCm39)	H520L	probably benign	Het
Mymk	A	T	2: 26,952,719 (GRCm39)	F130I	probably damaging	Het
Myo1f	C	T	17: 33,801,306 (GRCm39)	R333C	probably damaging	Het
Myo9a	T	A	9: 59,779,165 (GRCm39)	H1640Q	probably benign	Het
Nav1	A	G	1: 135,520,186 (GRCm39)		probably benign	Het
Ncbp3	G	T	11: 72,969,844 (GRCm39)	G564C	probably damaging	Het
Ncoa4	A	T	14: 31,898,682 (GRCm39)	I501L	probably benign	Het
Ngp	T	A	9: 110,249,883 (GRCm39)	N60K	possibly damaging	Het
Npc1l1	G	T	11: 6,178,215 (GRCm39)	D398E	probably damaging	Het
Nphs2	T	A	1: 156,153,701 (GRCm39)	M264K	probably damaging	Het
Or4s2b	G	A	2: 88,508,240 (GRCm39)	V14I	probably benign	Het
Or4s2b	T	G	2: 88,508,523 (GRCm39)	V101G	probably benign	Het
Or7e165	T	A	9: 19,694,442 (GRCm39)	Y4*	probably null	Het
Or8b8	T	A	9: 37,809,622 (GRCm39)	S307R	probably benign	Het
Patz1	A	G	11: 3,256,241 (GRCm39)	Y509C	probably damaging	Het
Pax8	G	A	2: 24,311,595 (GRCm39)	P447S	probably damaging	Het
Pde11a	A	G	2: 75,988,677 (GRCm39)	V488A	probably benign	Het
Pex11g	C	T	8: 3,515,899 (GRCm39)	V45M	probably benign	Het
Pik3ip1	T	A	11: 3,283,327 (GRCm39)	S142R	probably damaging	Het
Pitpnm2	C	G	5: 124,263,434 (GRCm39)	A819P	probably damaging	Het
Pla2g4e	T	G	2: 120,016,863 (GRCm39)	H226P	possibly damaging	Het
Plin4	T	A	17: 56,412,418 (GRCm39)	M538L	probably benign	Het
Ppp3cb	T	C	14: 20,570,714 (GRCm39)	N339S	possibly damaging	Het
Rev1	T	C	1: 38,092,730 (GRCm39)	E1202G	probably damaging	Het
Rngtt	T	A	4: 33,339,133 (GRCm39)		probably benign	Het
Serpinb12	T	A	1: 106,876,883 (GRCm39)	D66E	probably benign	Het
Sgsm1	A	T	5: 113,403,173 (GRCm39)	F958Y	probably damaging	Het
Slc35e2	T	C	4: 155,702,106 (GRCm39)	F290S	probably benign	Het
Sorl1	C	T	9: 41,943,210 (GRCm39)	V889M	possibly damaging	Het
Sptlc3	G	A	2: 139,478,600 (GRCm39)	V520I	probably benign	Het
Stam	A	T	2: 14,120,669 (GRCm39)	H53L	probably damaging	Het
Stox2	A	G	8: 47,645,970 (GRCm39)	S497P	probably damaging	Het
Tarbp1	A	G	8: 127,201,069 (GRCm39)	Y246H	probably damaging	Het
Tbx15	A	G	3: 99,259,683 (GRCm39)	Y518C	probably damaging	Het
Tdrd5	T	A	1: 156,111,944 (GRCm39)	T479S	probably benign	Het
Tescl	T	C	7: 24,032,683 (GRCm39)	E214G	probably damaging	Het
Tex10	T	C	4: 48,452,946 (GRCm39)	D671G	probably benign	Het
Tmem132d	A	G	5: 128,061,360 (GRCm39)	V414A	probably benign	Het
Tmem41b	T	A	7: 109,573,941 (GRCm39)		probably benign	Het
Tnfrsf18	A	G	4: 156,106,337 (GRCm39)		probably benign	Het
Tulp4	T	A	17: 6,249,108 (GRCm39)	D42E	probably damaging	Het
Ubtd1	A	G	19: 42,022,103 (GRCm39)	N125S	probably damaging	Het
Ubxn4	T	A	1: 128,183,186 (GRCm39)	F68I	probably benign	Het
Urb1	A	G	16: 90,573,159 (GRCm39)	S958P	probably benign	Het
Vash2	T	C	1: 190,692,498 (GRCm39)	S226G	probably benign	Het
Vmn2r120	C	T	17: 57,816,120 (GRCm39)	G745E	probably damaging	Het
Vmn2r58	T	A	7: 41,487,117 (GRCm39)	I593F	probably benign	Het
Zfp398	T	C	6: 47,817,361 (GRCm39)	L67P	probably damaging	Het
Zfp607b	T	A	7: 27,403,120 (GRCm39)	H525Q	probably damaging	Het
Zfp629	T	C	7: 127,211,492 (GRCm39)	T106A	probably benign	Het
Zfp980	G	A	4: 145,428,653 (GRCm39)	G461S	probably benign	Het
Zic5	T	A	14: 122,702,212 (GRCm39)	D173V	probably damaging	Het
Zranb2	G	A	3: 157,247,521 (GRCm39)		probably benign	Het

Other mutations in Fry

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00327:Fry	APN	5	150,263,869 (GRCm39)	nonsense	probably null
IGL00328:Fry	APN	5	150,263,869 (GRCm39)	nonsense	probably null
IGL00841:Fry	APN	5	150,346,189 (GRCm39)	missense	probably benign
IGL00938:Fry	APN	5	150,293,645 (GRCm39)	missense	probably damaging	1.00
IGL01015:Fry	APN	5	150,346,252 (GRCm39)	missense	probably benign	0.18
IGL01401:Fry	APN	5	150,362,253 (GRCm39)	missense	probably benign
IGL01616:Fry	APN	5	150,323,064 (GRCm39)	missense	probably damaging	1.00
IGL01616:Fry	APN	5	150,362,276 (GRCm39)	splice site	probably null
IGL01748:Fry	APN	5	150,269,116 (GRCm39)	splice site	probably benign
IGL01965:Fry	APN	5	150,305,086 (GRCm39)	missense	probably damaging	1.00
IGL02030:Fry	APN	5	150,395,083 (GRCm39)	splice site	probably benign
IGL02079:Fry	APN	5	150,323,089 (GRCm39)	missense	probably damaging	0.97
IGL02087:Fry	APN	5	150,327,059 (GRCm39)	missense	probably benign	0.23
IGL02113:Fry	APN	5	150,323,070 (GRCm39)	missense	probably benign
IGL02209:Fry	APN	5	150,360,491 (GRCm39)	missense	probably benign	0.00
IGL02250:Fry	APN	5	150,326,899 (GRCm39)	splice site	probably benign
IGL02265:Fry	APN	5	150,360,618 (GRCm39)	missense	probably damaging	1.00
IGL02486:Fry	APN	5	150,414,642 (GRCm39)	missense	probably damaging	0.99
IGL02552:Fry	APN	5	150,304,375 (GRCm39)	missense	probably damaging	1.00
IGL02881:Fry	APN	5	150,282,516 (GRCm39)	missense	probably damaging	0.99
IGL03008:Fry	APN	5	150,269,021 (GRCm39)	missense	possibly damaging	0.82
IGL03140:Fry	APN	5	150,419,166 (GRCm39)	missense	probably damaging	0.98
IGL03171:Fry	APN	5	150,304,274 (GRCm39)	missense	probably damaging	1.00
IGL03389:Fry	APN	5	150,317,696 (GRCm39)	missense	probably damaging	1.00
IGL03404:Fry	APN	5	150,249,633 (GRCm39)	missense	probably damaging	1.00
Brook	UTSW	5	150,249,597 (GRCm39)	missense	probably damaging	1.00
haydn	UTSW	5	150,341,929 (GRCm39)	missense	possibly damaging	0.94
miracle	UTSW	5	150,360,624 (GRCm39)	missense	probably damaging	0.99
quickening	UTSW	5	150,358,241 (GRCm39)	missense	probably damaging	1.00
seasons	UTSW	5	150,389,902 (GRCm39)	missense	probably benign	0.06
Vivaldi	UTSW	5	150,317,603 (GRCm39)	missense	possibly damaging	0.80
R0023:Fry	UTSW	5	150,374,563 (GRCm39)	missense	possibly damaging	0.78
R0024:Fry	UTSW	5	150,304,268 (GRCm39)	missense	probably benign	0.03
R0030:Fry	UTSW	5	150,296,034 (GRCm39)	nonsense	probably null
R0053:Fry	UTSW	5	150,384,842 (GRCm39)	splice site	probably benign
R0089:Fry	UTSW	5	150,263,892 (GRCm39)	missense	possibly damaging	0.91
R0212:Fry	UTSW	5	150,419,862 (GRCm39)	missense	probably damaging	0.99
R0241:Fry	UTSW	5	150,183,811 (GRCm39)	intron	probably benign
R0265:Fry	UTSW	5	150,358,241 (GRCm39)	missense	probably damaging	1.00
R0317:Fry	UTSW	5	150,394,933 (GRCm39)	missense	probably damaging	1.00
R0532:Fry	UTSW	5	150,402,226 (GRCm39)	splice site	probably benign
R0532:Fry	UTSW	5	150,357,172 (GRCm39)	unclassified	probably benign
R0599:Fry	UTSW	5	150,360,624 (GRCm39)	missense	probably damaging	0.99
R0631:Fry	UTSW	5	150,419,817 (GRCm39)	missense	possibly damaging	0.82
R0723:Fry	UTSW	5	150,419,825 (GRCm39)	missense	probably damaging	1.00
R0766:Fry	UTSW	5	150,326,897 (GRCm39)	splice site	probably benign
R0790:Fry	UTSW	5	150,389,902 (GRCm39)	missense	probably benign	0.06
R0928:Fry	UTSW	5	150,360,549 (GRCm39)	missense	probably damaging	1.00
R1104:Fry	UTSW	5	150,419,754 (GRCm39)	missense	probably damaging	1.00
R1144:Fry	UTSW	5	150,341,929 (GRCm39)	missense	possibly damaging	0.94
R1172:Fry	UTSW	5	150,404,959 (GRCm39)	nonsense	probably null
R1312:Fry	UTSW	5	150,326,897 (GRCm39)	splice site	probably benign
R1347:Fry	UTSW	5	150,419,283 (GRCm39)	missense	probably damaging	1.00
R1347:Fry	UTSW	5	150,419,283 (GRCm39)	missense	probably damaging	1.00
R1437:Fry	UTSW	5	150,233,890 (GRCm39)	missense	possibly damaging	0.92
R1458:Fry	UTSW	5	150,304,324 (GRCm39)	missense	probably damaging	1.00
R1542:Fry	UTSW	5	150,328,431 (GRCm39)	missense	probably benign	0.13
R1692:Fry	UTSW	5	150,293,692 (GRCm39)	missense	probably damaging	1.00
R1826:Fry	UTSW	5	150,360,174 (GRCm39)	missense	possibly damaging	0.82
R1874:Fry	UTSW	5	150,269,386 (GRCm39)	missense	probably damaging	1.00
R1875:Fry	UTSW	5	150,249,597 (GRCm39)	missense	probably damaging	1.00
R1881:Fry	UTSW	5	150,401,511 (GRCm39)	missense	probably damaging	0.97
R1884:Fry	UTSW	5	150,326,985 (GRCm39)	missense	probably benign	0.00
R1929:Fry	UTSW	5	150,324,389 (GRCm39)	missense	probably null	0.02
R2066:Fry	UTSW	5	150,293,584 (GRCm39)	splice site	probably benign
R2270:Fry	UTSW	5	150,324,389 (GRCm39)	missense	probably null	0.02
R2356:Fry	UTSW	5	150,394,897 (GRCm39)	missense	probably benign
R3720:Fry	UTSW	5	150,378,037 (GRCm39)	missense	probably damaging	1.00
R3773:Fry	UTSW	5	150,321,663 (GRCm39)	missense	probably damaging	0.96
R3824:Fry	UTSW	5	150,419,884 (GRCm39)	missense	possibly damaging	0.94
R3902:Fry	UTSW	5	150,269,392 (GRCm39)	missense	probably damaging	1.00
R3923:Fry	UTSW	5	150,336,814 (GRCm39)	missense	probably benign
R4250:Fry	UTSW	5	150,233,825 (GRCm39)	missense	probably damaging	0.99
R4332:Fry	UTSW	5	150,305,128 (GRCm39)	missense	probably damaging	1.00
R4495:Fry	UTSW	5	150,233,928 (GRCm39)	missense	probably damaging	1.00
R4682:Fry	UTSW	5	150,346,219 (GRCm39)	missense	probably damaging	1.00
R4732:Fry	UTSW	5	150,309,472 (GRCm39)	missense
R4733:Fry	UTSW	5	150,309,472 (GRCm39)	missense
R4755:Fry	UTSW	5	150,321,719 (GRCm39)	missense	probably damaging	0.99
R4788:Fry	UTSW	5	150,323,101 (GRCm39)	missense	probably benign	0.00
R4803:Fry	UTSW	5	150,322,998 (GRCm39)	missense	probably benign	0.31
R4858:Fry	UTSW	5	150,325,108 (GRCm39)	missense	possibly damaging	0.78
R4872:Fry	UTSW	5	150,317,704 (GRCm39)	critical splice donor site	probably null
R4902:Fry	UTSW	5	150,419,168 (GRCm39)	missense	probably benign	0.43
R4915:Fry	UTSW	5	150,402,328 (GRCm39)	missense	probably benign	0.30
R4938:Fry	UTSW	5	150,401,454 (GRCm39)	missense	probably damaging	1.00
R4983:Fry	UTSW	5	150,321,719 (GRCm39)	missense	probably damaging	1.00
R5004:Fry	UTSW	5	150,357,069 (GRCm39)	missense	probably benign	0.16
R5040:Fry	UTSW	5	150,312,319 (GRCm39)	missense	probably damaging	0.99
R5145:Fry	UTSW	5	150,293,689 (GRCm39)	missense	probably damaging	0.98
R5170:Fry	UTSW	5	150,353,319 (GRCm39)	missense	probably benign	0.03
R5233:Fry	UTSW	5	150,393,185 (GRCm39)	missense	possibly damaging	0.71
R5428:Fry	UTSW	5	150,328,824 (GRCm39)	missense	possibly damaging	0.89
R5468:Fry	UTSW	5	150,323,053 (GRCm39)	missense	probably benign	0.44
R5481:Fry	UTSW	5	150,183,784 (GRCm39)	missense	probably benign	0.01
R5494:Fry	UTSW	5	150,314,132 (GRCm39)	missense	probably damaging	1.00
R5538:Fry	UTSW	5	150,419,313 (GRCm39)	missense	probably damaging	1.00
R5638:Fry	UTSW	5	150,282,546 (GRCm39)	missense	possibly damaging	0.46
R5645:Fry	UTSW	5	150,304,332 (GRCm39)	missense	probably damaging	1.00
R5716:Fry	UTSW	5	150,293,686 (GRCm39)	nonsense	probably null
R5812:Fry	UTSW	5	150,323,136 (GRCm39)	missense	probably damaging	0.99
R5813:Fry	UTSW	5	150,323,136 (GRCm39)	missense	probably damaging	0.99
R5873:Fry	UTSW	5	150,302,350 (GRCm39)	missense	probably damaging	1.00
R5933:Fry	UTSW	5	150,314,265 (GRCm39)	intron	probably benign
R6037:Fry	UTSW	5	150,351,644 (GRCm39)	missense	probably benign	0.03
R6037:Fry	UTSW	5	150,351,644 (GRCm39)	missense	probably benign	0.03
R6158:Fry	UTSW	5	150,378,037 (GRCm39)	missense	probably damaging	1.00
R6178:Fry	UTSW	5	150,377,987 (GRCm39)	missense	probably damaging	1.00
R6481:Fry	UTSW	5	150,309,479 (GRCm39)	missense	probably damaging	1.00
R6562:Fry	UTSW	5	150,249,614 (GRCm39)	missense	probably damaging	1.00
R6676:Fry	UTSW	5	150,304,387 (GRCm39)	missense	probably benign	0.22
R6717:Fry	UTSW	5	150,419,777 (GRCm39)	missense	probably benign	0.00
R6828:Fry	UTSW	5	150,389,911 (GRCm39)	splice site	probably null
R6874:Fry	UTSW	5	150,360,768 (GRCm39)	missense	probably benign	0.00
R6930:Fry	UTSW	5	150,351,695 (GRCm39)	missense	probably benign	0.00
R6963:Fry	UTSW	5	150,381,309 (GRCm39)	missense	probably benign	0.17
R6965:Fry	UTSW	5	150,339,685 (GRCm39)	missense	possibly damaging	0.79
R7051:Fry	UTSW	5	150,318,634 (GRCm39)	missense	possibly damaging	0.93
R7085:Fry	UTSW	5	150,362,214 (GRCm39)	missense	probably benign	0.02
R7108:Fry	UTSW	5	150,414,555 (GRCm39)	missense
R7108:Fry	UTSW	5	150,319,251 (GRCm39)	missense	probably damaging	1.00
R7115:Fry	UTSW	5	150,309,532 (GRCm39)	missense	probably damaging	1.00
R7116:Fry	UTSW	5	150,319,334 (GRCm39)	critical splice donor site	probably null
R7197:Fry	UTSW	5	150,393,232 (GRCm39)	missense
R7256:Fry	UTSW	5	150,390,251 (GRCm39)	missense
R7318:Fry	UTSW	5	150,360,458 (GRCm39)	missense	probably damaging	0.98
R7323:Fry	UTSW	5	150,419,814 (GRCm39)	missense
R7358:Fry	UTSW	5	150,339,788 (GRCm39)	missense	probably benign
R7361:Fry	UTSW	5	150,360,312 (GRCm39)	missense	possibly damaging	0.92
R7395:Fry	UTSW	5	150,304,348 (GRCm39)	missense	possibly damaging	0.82
R7487:Fry	UTSW	5	150,338,039 (GRCm39)	missense	possibly damaging	0.79
R7491:Fry	UTSW	5	150,389,791 (GRCm39)	missense
R7574:Fry	UTSW	5	150,304,359 (GRCm39)	missense	probably benign	0.00
R7582:Fry	UTSW	5	150,419,847 (GRCm39)	missense
R7586:Fry	UTSW	5	150,349,683 (GRCm39)	missense	probably damaging	1.00
R7650:Fry	UTSW	5	150,336,883 (GRCm39)	missense	probably damaging	1.00
R7699:Fry	UTSW	5	150,328,792 (GRCm39)	missense	probably damaging	0.98
R7700:Fry	UTSW	5	150,328,792 (GRCm39)	missense	probably damaging	0.98
R7972:Fry	UTSW	5	150,233,861 (GRCm39)	missense	probably benign	0.05
R8058:Fry	UTSW	5	150,419,232 (GRCm39)	missense
R8070:Fry	UTSW	5	150,401,472 (GRCm39)	missense
R8159:Fry	UTSW	5	150,322,998 (GRCm39)	missense	probably benign	0.31
R8202:Fry	UTSW	5	150,355,202 (GRCm39)	missense	probably damaging	1.00
R8261:Fry	UTSW	5	150,369,372 (GRCm39)	missense	probably damaging	1.00
R8279:Fry	UTSW	5	150,419,726 (GRCm39)	missense
R8338:Fry	UTSW	5	150,282,516 (GRCm39)	missense	probably damaging	0.99
R8370:Fry	UTSW	5	150,319,284 (GRCm39)	missense	probably damaging	1.00
R8673:Fry	UTSW	5	150,318,576 (GRCm39)	missense	possibly damaging	0.91
R8786:Fry	UTSW	5	150,317,501 (GRCm39)	missense	probably benign	0.00
R8815:Fry	UTSW	5	150,317,603 (GRCm39)	missense	possibly damaging	0.80
R8847:Fry	UTSW	5	150,309,472 (GRCm39)	missense
R9023:Fry	UTSW	5	150,360,768 (GRCm39)	missense	probably benign	0.00
R9025:Fry	UTSW	5	150,219,273 (GRCm39)	intron	probably benign
R9125:Fry	UTSW	5	150,269,525 (GRCm39)	missense	probably damaging	0.97
R9172:Fry	UTSW	5	150,336,793 (GRCm39)	missense	probably benign
R9262:Fry	UTSW	5	150,305,109 (GRCm39)	missense	probably damaging	1.00
R9263:Fry	UTSW	5	150,322,728 (GRCm39)	missense	probably damaging	1.00
R9293:Fry	UTSW	5	150,419,297 (GRCm39)	missense
R9368:Fry	UTSW	5	150,401,403 (GRCm39)	missense
R9401:Fry	UTSW	5	150,302,403 (GRCm39)	missense	probably damaging	1.00
R9402:Fry	UTSW	5	150,360,318 (GRCm39)	missense	probably damaging	1.00
R9402:Fry	UTSW	5	150,357,161 (GRCm39)	missense	possibly damaging	0.91
R9420:Fry	UTSW	5	150,356,994 (GRCm39)	missense	possibly damaging	0.72
R9557:Fry	UTSW	5	150,389,781 (GRCm39)	missense
R9647:Fry	UTSW	5	150,292,984 (GRCm39)	missense	probably damaging	1.00
R9650:Fry	UTSW	5	150,369,375 (GRCm39)	missense	probably damaging	1.00
R9655:Fry	UTSW	5	150,362,251 (GRCm39)	missense	possibly damaging	0.90
R9664:Fry	UTSW	5	150,282,488 (GRCm39)	missense	probably damaging	0.98
R9668:Fry	UTSW	5	150,282,318 (GRCm39)	missense	probably damaging	1.00
R9732:Fry	UTSW	5	150,328,758 (GRCm39)	missense	probably benign	0.00
R9773:Fry	UTSW	5	150,322,728 (GRCm39)	missense	probably damaging	1.00
Z1177:Fry	UTSW	5	150,233,902 (GRCm39)	missense	possibly damaging	0.80

Predicted Primers

PCR Primer
(F):5'- GCATATCCTTTCTTCCACCTAGAAG -3'
(R):5'- TAAAGGTTCCCTAGGCTGCCTC -3'

Sequencing Primer
(F):5'- GAAAATGTAACCAAGTCAGCGATCTC -3'
(R):5'- ACATGAGTGTATGTGTGAGTGTG -3'

Posted On

2015-09-25