Incidental Mutation 'R4717:Plxnb2'
| ID |
354170 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnb2
|
| Ensembl Gene |
ENSMUSG00000036606 |
| Gene Name |
plexin B2 |
| Synonyms |
1110007H23Rik, Debt |
| MMRRC Submission |
041984-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.938)
|
| Stock # |
R4717 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
15 |
| Chromosomal Location |
89039752-89064960 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
A to T
at 89041622 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Stop codon
at position 1727
(C1727*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000104955
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000060808]
[ENSMUST00000109331]
|
| AlphaFold |
B2RXS4 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000060808
AA Change: C1727*
|
| SMART Domains |
Protein: ENSMUSP00000051731
Gene: ENSMUSG00000036606
AA Change: C1727*
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Sema
|
34 |
452 |
8.87e-92 |
SMART |
|
PSI
|
470 |
521 |
1.94e-10 |
SMART |
|
PSI
|
616 |
669 |
4.09e-1 |
SMART |
|
PSI
|
761 |
804 |
7.02e-8 |
SMART |
|
IPT
|
805 |
896 |
8.14e-19 |
SMART |
|
IPT
|
897 |
983 |
1.1e-15 |
SMART |
|
IPT
|
985 |
1096 |
5.06e-6 |
SMART |
|
Pfam:Plexin_cytopl
|
1275 |
1809 |
1.6e-225 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000109331
AA Change: C1727*
|
| SMART Domains |
Protein: ENSMUSP00000104955
Gene: ENSMUSG00000036606
AA Change: C1727*
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Sema
|
34 |
452 |
8.87e-92 |
SMART |
|
PSI
|
470 |
521 |
1.94e-10 |
SMART |
|
PSI
|
616 |
669 |
4.09e-1 |
SMART |
|
PSI
|
761 |
804 |
7.02e-8 |
SMART |
|
IPT
|
805 |
896 |
8.14e-19 |
SMART |
|
IPT
|
897 |
983 |
1.1e-15 |
SMART |
|
IPT
|
985 |
1096 |
5.06e-6 |
SMART |
|
Pfam:Plexin_cytopl
|
1274 |
1809 |
4.4e-251 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139372
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000143014
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151418
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000229966
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000230393
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. (2002) [PubMed 12183458]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Homozygotes for a targeted mutation of this gene die perinatally of exencephaly or survive and seem normal despite severe abnormalities in cerebellar layering and foliation; the external granule cell layer is disorganized due to continued proliferation and migration of differentiated granule cells. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9330159F19Rik |
T |
C |
10: 29,097,783 (GRCm39) |
L60P |
probably damaging |
Het |
| Acsf2 |
T |
G |
11: 94,450,372 (GRCm39) |
M512L |
probably benign |
Het |
| Ahrr |
T |
A |
13: 74,363,885 (GRCm39) |
H312L |
probably benign |
Het |
| Akr1c18 |
T |
C |
13: 4,186,717 (GRCm39) |
M244V |
probably benign |
Het |
| Aldh3b2 |
A |
G |
19: 4,031,128 (GRCm39) |
Y459C |
probably damaging |
Het |
| Arhgap29 |
A |
T |
3: 121,803,607 (GRCm39) |
I796L |
possibly damaging |
Het |
| Arrdc4 |
T |
A |
7: 68,391,406 (GRCm39) |
D287V |
probably damaging |
Het |
| Astn2 |
A |
T |
4: 65,562,991 (GRCm39) |
I930N |
possibly damaging |
Het |
| Bace2 |
T |
A |
16: 97,238,073 (GRCm39) |
L508Q |
probably damaging |
Het |
| Baz2a |
G |
T |
10: 127,960,811 (GRCm39) |
C1537F |
possibly damaging |
Het |
| Cad |
A |
G |
5: 31,224,030 (GRCm39) |
|
probably null |
Het |
| Capn5 |
A |
T |
7: 97,773,126 (GRCm39) |
I626N |
probably benign |
Het |
| Car8 |
A |
T |
4: 8,169,685 (GRCm39) |
N274K |
probably damaging |
Het |
| Casp14 |
T |
C |
10: 78,550,958 (GRCm39) |
I76V |
probably benign |
Het |
| Ccdc88c |
A |
G |
12: 100,882,925 (GRCm39) |
V1649A |
probably benign |
Het |
| Cemip |
A |
T |
7: 83,596,488 (GRCm39) |
I1092N |
probably damaging |
Het |
| Clspn |
A |
G |
4: 126,453,849 (GRCm39) |
N91D |
probably damaging |
Het |
| Cpxm2 |
A |
G |
7: 131,656,574 (GRCm39) |
Y563H |
possibly damaging |
Het |
| Csnk1g2 |
T |
C |
10: 80,473,749 (GRCm39) |
V72A |
probably benign |
Het |
| Cyp46a1 |
T |
C |
12: 108,318,285 (GRCm39) |
|
probably null |
Het |
| Cyp4x1 |
T |
C |
4: 114,978,902 (GRCm39) |
H206R |
probably benign |
Het |
| Dapk1 |
T |
A |
13: 60,874,476 (GRCm39) |
|
probably null |
Het |
| Ddx1 |
A |
G |
12: 13,290,888 (GRCm39) |
W76R |
probably damaging |
Het |
| Dhx29 |
G |
A |
13: 113,083,469 (GRCm39) |
R508H |
unknown |
Het |
| Dnah2 |
T |
C |
11: 69,320,183 (GRCm39) |
D3962G |
probably benign |
Het |
| Dnajc14 |
T |
A |
10: 128,642,113 (GRCm39) |
C12S |
possibly damaging |
Het |
| Dock1 |
T |
C |
7: 134,449,899 (GRCm39) |
I804T |
probably damaging |
Het |
| Efs |
G |
T |
14: 55,157,801 (GRCm39) |
S170Y |
probably damaging |
Het |
| Eml4 |
G |
T |
17: 83,755,654 (GRCm39) |
W295C |
probably benign |
Het |
| Fkbp15 |
A |
G |
4: 62,226,306 (GRCm39) |
S748P |
probably damaging |
Het |
| Ghr |
T |
G |
15: 3,349,235 (GRCm39) |
I648L |
possibly damaging |
Het |
| Gigyf1 |
T |
A |
5: 137,523,494 (GRCm39) |
I942N |
probably damaging |
Het |
| Gpam |
T |
A |
19: 55,064,046 (GRCm39) |
E682D |
probably benign |
Het |
| Gsr |
A |
T |
8: 34,183,886 (GRCm39) |
K383* |
probably null |
Het |
| Hapln1 |
C |
A |
13: 89,753,579 (GRCm39) |
S248R |
probably benign |
Het |
| Haus2 |
G |
T |
2: 120,449,583 (GRCm39) |
R209L |
probably benign |
Het |
| Hhatl |
A |
G |
9: 121,618,943 (GRCm39) |
F63S |
probably damaging |
Het |
| Hmcn1 |
A |
G |
1: 150,494,816 (GRCm39) |
M4091T |
probably benign |
Het |
| Hspb7 |
A |
G |
4: 141,149,896 (GRCm39) |
D94G |
probably damaging |
Het |
| Irf6 |
T |
A |
1: 192,849,742 (GRCm39) |
|
probably null |
Het |
| Itgb2 |
T |
A |
10: 77,381,878 (GRCm39) |
L60* |
probably null |
Het |
| Jmjd1c |
C |
T |
10: 66,993,830 (GRCm39) |
Q104* |
probably null |
Het |
| Kcnh1 |
A |
G |
1: 191,959,025 (GRCm39) |
D193G |
probably damaging |
Het |
| Klhl25 |
G |
T |
7: 75,516,528 (GRCm39) |
C478F |
probably damaging |
Het |
| Klhl3 |
T |
C |
13: 58,178,330 (GRCm39) |
D267G |
probably damaging |
Het |
| L3mbtl4 |
T |
G |
17: 68,762,708 (GRCm39) |
H80Q |
probably null |
Het |
| Lhcgr |
C |
A |
17: 89,049,895 (GRCm39) |
V544F |
probably benign |
Het |
| Mfsd4a |
T |
C |
1: 131,985,633 (GRCm39) |
N168D |
probably benign |
Het |
| Mmp3 |
A |
G |
9: 7,449,881 (GRCm39) |
Q255R |
possibly damaging |
Het |
| Mrgprb3 |
C |
A |
7: 48,293,000 (GRCm39) |
G184C |
probably benign |
Het |
| Mtpap |
C |
T |
18: 4,396,394 (GRCm39) |
A562V |
possibly damaging |
Het |
| Nid1 |
T |
C |
13: 13,681,086 (GRCm39) |
V1072A |
probably benign |
Het |
| Nsf |
T |
G |
11: 103,714,595 (GRCm39) |
K728T |
probably damaging |
Het |
| Or10ak7 |
T |
C |
4: 118,791,626 (GRCm39) |
N140D |
probably benign |
Het |
| Or12j3 |
T |
C |
7: 139,953,328 (GRCm39) |
N65S |
probably damaging |
Het |
| Or1e17 |
T |
A |
11: 73,831,641 (GRCm39) |
S190T |
possibly damaging |
Het |
| Or2a5 |
T |
C |
6: 42,874,158 (GRCm39) |
Y258H |
probably damaging |
Het |
| Or4k15b |
A |
T |
14: 50,272,821 (GRCm39) |
V13E |
probably damaging |
Het |
| Pcsk5 |
A |
T |
19: 17,502,631 (GRCm39) |
C894S |
probably damaging |
Het |
| Pde2a |
A |
G |
7: 101,143,879 (GRCm39) |
D166G |
probably benign |
Het |
| Pfpl |
G |
A |
19: 12,406,618 (GRCm39) |
E290K |
probably benign |
Het |
| Pi4kb |
A |
C |
3: 94,906,162 (GRCm39) |
I570L |
probably damaging |
Het |
| Poln |
A |
T |
5: 34,286,792 (GRCm39) |
D125E |
possibly damaging |
Het |
| Pomgnt1 |
A |
G |
4: 116,011,412 (GRCm39) |
D259G |
possibly damaging |
Het |
| Prx |
A |
T |
7: 27,216,152 (GRCm39) |
M218L |
probably benign |
Het |
| Pxn |
A |
T |
5: 115,690,001 (GRCm39) |
Q342L |
probably damaging |
Het |
| Rhpn2 |
A |
G |
7: 35,033,775 (GRCm39) |
D3G |
possibly damaging |
Het |
| Rnase2b |
C |
T |
14: 51,400,174 (GRCm39) |
T85I |
possibly damaging |
Het |
| Rnaseh2b |
C |
A |
14: 62,591,075 (GRCm39) |
T142K |
probably damaging |
Het |
| Sacs |
T |
C |
14: 61,450,304 (GRCm39) |
S4117P |
probably damaging |
Het |
| Sdk2 |
T |
C |
11: 113,745,195 (GRCm39) |
N700S |
probably damaging |
Het |
| Sec62 |
A |
C |
3: 30,864,020 (GRCm39) |
K101Q |
unknown |
Het |
| Sel1l2 |
A |
C |
2: 140,071,943 (GRCm39) |
L659R |
possibly damaging |
Het |
| Septin11 |
A |
G |
5: 93,304,815 (GRCm39) |
I211V |
possibly damaging |
Het |
| Slc25a42 |
C |
T |
8: 70,642,107 (GRCm39) |
E112K |
probably damaging |
Het |
| Spem2 |
T |
C |
11: 69,708,609 (GRCm39) |
N119D |
probably benign |
Het |
| Themis |
G |
A |
10: 28,665,748 (GRCm39) |
E604K |
probably benign |
Het |
| Tie1 |
T |
C |
4: 118,343,414 (GRCm39) |
K150E |
probably damaging |
Het |
| Top6bl |
A |
G |
19: 4,675,901 (GRCm39) |
|
probably benign |
Het |
| Ubap2 |
G |
A |
4: 41,218,333 (GRCm39) |
T258I |
possibly damaging |
Het |
| Ushbp1 |
C |
T |
8: 71,838,313 (GRCm39) |
A664T |
probably damaging |
Het |
| Vmn1r1 |
T |
C |
1: 181,984,774 (GRCm39) |
N297S |
possibly damaging |
Het |
| Vmn1r173 |
A |
C |
7: 23,402,637 (GRCm39) |
I291L |
probably damaging |
Het |
| Yy1 |
A |
G |
12: 108,759,972 (GRCm39) |
I212V |
possibly damaging |
Het |
| Zfp442 |
A |
T |
2: 150,250,149 (GRCm39) |
F527L |
probably damaging |
Het |
| Zyg11b |
T |
A |
4: 108,099,069 (GRCm39) |
H632L |
probably damaging |
Het |
|
| Other mutations in Plxnb2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00546:Plxnb2
|
APN |
15 |
89,046,569 (GRCm39) |
splice site |
probably benign |
|
|
IGL01574:Plxnb2
|
APN |
15 |
89,046,886 (GRCm39) |
splice site |
probably null |
|
|
IGL01695:Plxnb2
|
APN |
15 |
89,041,417 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL01763:Plxnb2
|
APN |
15 |
89,046,184 (GRCm39) |
splice site |
probably null |
|
|
IGL01921:Plxnb2
|
APN |
15 |
89,048,474 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL02129:Plxnb2
|
APN |
15 |
89,044,613 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02153:Plxnb2
|
APN |
15 |
89,050,016 (GRCm39) |
nonsense |
probably null |
|
|
IGL02637:Plxnb2
|
APN |
15 |
89,048,260 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
IGL02892:Plxnb2
|
APN |
15 |
89,045,425 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03108:Plxnb2
|
APN |
15 |
89,042,234 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL03115:Plxnb2
|
APN |
15 |
89,046,641 (GRCm39) |
splice site |
probably benign |
|
|
P0040:Plxnb2
|
UTSW |
15 |
89,047,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0022:Plxnb2
|
UTSW |
15 |
89,047,479 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0095:Plxnb2
|
UTSW |
15 |
89,049,534 (GRCm39) |
missense |
probably benign |
|
|
R0103:Plxnb2
|
UTSW |
15 |
89,045,972 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0544:Plxnb2
|
UTSW |
15 |
89,042,816 (GRCm39) |
splice site |
probably benign |
|
|
R0671:Plxnb2
|
UTSW |
15 |
89,042,184 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1279:Plxnb2
|
UTSW |
15 |
89,046,524 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1530:Plxnb2
|
UTSW |
15 |
89,051,395 (GRCm39) |
missense |
probably benign |
|
|
R1542:Plxnb2
|
UTSW |
15 |
89,050,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1610:Plxnb2
|
UTSW |
15 |
89,042,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1686:Plxnb2
|
UTSW |
15 |
89,046,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1702:Plxnb2
|
UTSW |
15 |
89,046,187 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1996:Plxnb2
|
UTSW |
15 |
89,042,971 (GRCm39) |
missense |
probably benign |
0.13 |
|
R1997:Plxnb2
|
UTSW |
15 |
89,042,971 (GRCm39) |
missense |
probably benign |
0.13 |
|
R2031:Plxnb2
|
UTSW |
15 |
89,047,013 (GRCm39) |
nonsense |
probably null |
|
|
R2049:Plxnb2
|
UTSW |
15 |
89,043,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2072:Plxnb2
|
UTSW |
15 |
89,042,654 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2076:Plxnb2
|
UTSW |
15 |
89,042,229 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2140:Plxnb2
|
UTSW |
15 |
89,040,765 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2418:Plxnb2
|
UTSW |
15 |
89,045,272 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2419:Plxnb2
|
UTSW |
15 |
89,045,272 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R3752:Plxnb2
|
UTSW |
15 |
89,041,458 (GRCm39) |
splice site |
probably benign |
|
|
R3825:Plxnb2
|
UTSW |
15 |
89,050,602 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4154:Plxnb2
|
UTSW |
15 |
89,043,845 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4197:Plxnb2
|
UTSW |
15 |
89,041,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4385:Plxnb2
|
UTSW |
15 |
89,044,826 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4434:Plxnb2
|
UTSW |
15 |
89,047,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4678:Plxnb2
|
UTSW |
15 |
89,045,131 (GRCm39) |
missense |
probably benign |
0.37 |
|
R4773:Plxnb2
|
UTSW |
15 |
89,051,150 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4905:Plxnb2
|
UTSW |
15 |
89,041,614 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5368:Plxnb2
|
UTSW |
15 |
89,043,796 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5418:Plxnb2
|
UTSW |
15 |
89,050,694 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5484:Plxnb2
|
UTSW |
15 |
89,048,412 (GRCm39) |
splice site |
probably null |
|
|
R5520:Plxnb2
|
UTSW |
15 |
89,051,746 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5566:Plxnb2
|
UTSW |
15 |
89,048,223 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5568:Plxnb2
|
UTSW |
15 |
89,041,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5619:Plxnb2
|
UTSW |
15 |
89,047,012 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5685:Plxnb2
|
UTSW |
15 |
89,051,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5688:Plxnb2
|
UTSW |
15 |
89,042,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5809:Plxnb2
|
UTSW |
15 |
89,051,774 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R5813:Plxnb2
|
UTSW |
15 |
89,044,962 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5866:Plxnb2
|
UTSW |
15 |
89,051,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6016:Plxnb2
|
UTSW |
15 |
89,045,225 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R6117:Plxnb2
|
UTSW |
15 |
89,042,203 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6187:Plxnb2
|
UTSW |
15 |
89,051,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6260:Plxnb2
|
UTSW |
15 |
89,049,494 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6263:Plxnb2
|
UTSW |
15 |
89,046,189 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6269:Plxnb2
|
UTSW |
15 |
89,044,916 (GRCm39) |
missense |
probably benign |
0.18 |
|
R6351:Plxnb2
|
UTSW |
15 |
89,041,973 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6522:Plxnb2
|
UTSW |
15 |
89,048,629 (GRCm39) |
missense |
probably benign |
0.18 |
|
R6856:Plxnb2
|
UTSW |
15 |
89,048,523 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6930:Plxnb2
|
UTSW |
15 |
89,044,592 (GRCm39) |
missense |
probably benign |
|
|
R7354:Plxnb2
|
UTSW |
15 |
89,049,928 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7513:Plxnb2
|
UTSW |
15 |
89,042,525 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7522:Plxnb2
|
UTSW |
15 |
89,045,977 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7730:Plxnb2
|
UTSW |
15 |
89,046,533 (GRCm39) |
missense |
probably benign |
|
|
R7766:Plxnb2
|
UTSW |
15 |
89,045,474 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7781:Plxnb2
|
UTSW |
15 |
89,041,225 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8126:Plxnb2
|
UTSW |
15 |
89,047,506 (GRCm39) |
missense |
probably benign |
|
|
R8131:Plxnb2
|
UTSW |
15 |
89,042,916 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8372:Plxnb2
|
UTSW |
15 |
89,042,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8736:Plxnb2
|
UTSW |
15 |
89,046,261 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8772:Plxnb2
|
UTSW |
15 |
89,046,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9022:Plxnb2
|
UTSW |
15 |
89,048,471 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R9044:Plxnb2
|
UTSW |
15 |
89,044,566 (GRCm39) |
splice site |
probably benign |
|
|
R9253:Plxnb2
|
UTSW |
15 |
89,052,015 (GRCm39) |
missense |
probably benign |
|
|
R9398:Plxnb2
|
UTSW |
15 |
89,045,122 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9562:Plxnb2
|
UTSW |
15 |
89,050,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9568:Plxnb2
|
UTSW |
15 |
89,045,160 (GRCm39) |
nonsense |
probably null |
|
|
R9613:Plxnb2
|
UTSW |
15 |
89,048,496 (GRCm39) |
missense |
probably benign |
0.01 |
|
X0027:Plxnb2
|
UTSW |
15 |
89,044,916 (GRCm39) |
missense |
probably benign |
0.18 |
|
Z1177:Plxnb2
|
UTSW |
15 |
89,043,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCCTGCGGAAGACAAAAGC -3'
(R):5'- CCATATCTGGAAAACCAACAGGTG -3'
Sequencing Primer
(F):5'- AAAGCTTTTGACACTGGGCTAGC -3'
(R):5'- ACCAACAGGTGAGGCTTCTG -3'
|
| Posted On |
2015-10-21 |
Incidental Mutation