Incidental Mutation 'R7399:Nup205'
| ID |
574023 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nup205
|
| Ensembl Gene |
ENSMUSG00000038759 |
| Gene Name |
nucleoporin 205 |
| Synonyms |
3830404O05Rik |
| MMRRC Submission |
045481-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.962)
|
| Stock # |
R7399 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
35154551-35224534 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 35191611 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Asparagine
at position 1032
(I1032N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000144126
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043815]
[ENSMUST00000170234]
[ENSMUST00000201374]
|
| AlphaFold |
A0A0J9YUD5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000043815
AA Change: I979N
PolyPhen 2
Score 0.992 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000039656
Gene: ENSMUSG00000038759
AA Change: I979N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
13 |
N/A |
INTRINSIC |
|
Pfam:Nup192
|
14 |
1684 |
N/A |
PFAM |
|
low complexity region
|
1995 |
2005 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000170234
|
| SMART Domains |
Protein: ENSMUSP00000130033
Gene: ENSMUSG00000038759
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3414
|
13 |
322 |
9.7e-98 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000201374
AA Change: I1032N
PolyPhen 2
Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000144126
Gene: ENSMUSG00000038759
AA Change: I1032N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
36 |
50 |
N/A |
INTRINSIC |
|
Pfam:Nup192
|
67 |
1737 |
N/A |
PFAM |
|
low complexity region
|
2048 |
2058 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.5835 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
99% (74/75) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a nucleoporin, which is a subunit of the nuclear pore complex that functions in active transport of proteins, RNAs and ribonucleoprotein particles between the nucleus and cytoplasm. Mutations in this gene are associated with steroid-resistant nephrotic syndrome. [provided by RefSeq, Jul 2016]
|
| Allele List at MGI |
All alleles(32) : Targeted(2) Gene trapped(30)
|
| Other mutations in this stock |
Total: 74 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acaca |
T |
G |
11: 84,151,505 (GRCm39) |
V801G |
possibly damaging |
Het |
| Actbl2 |
T |
A |
13: 111,392,127 (GRCm39) |
M154K |
probably benign |
Het |
| Adam7 |
A |
T |
14: 68,741,915 (GRCm39) |
|
probably null |
Het |
| Arfgef1 |
T |
A |
1: 10,251,122 (GRCm39) |
T888S |
probably benign |
Het |
| AW554918 |
C |
T |
18: 25,302,117 (GRCm39) |
P10L |
possibly damaging |
Het |
| Bcap29 |
A |
G |
12: 31,680,881 (GRCm39) |
I35T |
probably damaging |
Het |
| Bhlhe40 |
TG |
TGG |
6: 108,641,818 (GRCm39) |
254 |
probably null |
Het |
| Cby2 |
A |
G |
14: 75,830,077 (GRCm39) |
S39P |
probably benign |
Het |
| Cdc25b |
A |
G |
2: 131,036,574 (GRCm39) |
D458G |
probably damaging |
Het |
| Cdc42bpb |
T |
C |
12: 111,272,101 (GRCm39) |
K1104R |
probably benign |
Het |
| Cep89 |
A |
G |
7: 35,137,803 (GRCm39) |
N729S |
probably damaging |
Het |
| Clec4a4 |
T |
A |
6: 122,968,788 (GRCm39) |
M51K |
possibly damaging |
Het |
| Dcdc2b |
A |
G |
4: 129,503,422 (GRCm39) |
L270P |
probably damaging |
Het |
| Dennd5b |
G |
T |
6: 148,937,981 (GRCm39) |
H639N |
probably damaging |
Het |
| Dnah11 |
T |
G |
12: 117,991,212 (GRCm39) |
T2385P |
probably benign |
Het |
| Dnah11 |
T |
C |
12: 118,089,520 (GRCm39) |
E1182G |
probably damaging |
Het |
| Dok7 |
T |
C |
5: 35,223,815 (GRCm39) |
V81A |
probably damaging |
Het |
| Dtx1 |
T |
A |
5: 120,820,458 (GRCm39) |
M494L |
possibly damaging |
Het |
| Foxj1 |
A |
T |
11: 116,223,080 (GRCm39) |
L241Q |
possibly damaging |
Het |
| Gbp10 |
G |
A |
5: 105,384,015 (GRCm39) |
|
probably benign |
Het |
| Hnmt |
T |
A |
2: 23,893,892 (GRCm39) |
T201S |
probably benign |
Het |
| Jup |
G |
T |
11: 100,269,177 (GRCm39) |
T412K |
possibly damaging |
Het |
| Kcnh2 |
G |
A |
5: 24,527,057 (GRCm39) |
S954F |
probably damaging |
Het |
| Klhdc7b |
A |
C |
15: 89,272,847 (GRCm39) |
K585T |
possibly damaging |
Het |
| Klk7 |
T |
A |
7: 43,461,424 (GRCm39) |
S14T |
probably benign |
Het |
| Lama4 |
G |
A |
10: 38,923,944 (GRCm39) |
E451K |
probably damaging |
Het |
| Ldhb |
A |
G |
6: 142,441,399 (GRCm39) |
C164R |
probably damaging |
Het |
| Malrd1 |
G |
A |
2: 15,614,901 (GRCm39) |
D239N |
|
Het |
| Mgam |
T |
A |
6: 40,643,788 (GRCm39) |
V572E |
probably damaging |
Het |
| Mrgprb2 |
G |
T |
7: 48,201,890 (GRCm39) |
N278K |
probably damaging |
Het |
| Msto1 |
A |
G |
3: 88,819,130 (GRCm39) |
Y206H |
probably damaging |
Het |
| Myo6 |
A |
G |
9: 80,169,573 (GRCm39) |
S467G |
unknown |
Het |
| Mysm1 |
T |
A |
4: 94,849,964 (GRCm39) |
I447L |
probably benign |
Het |
| Nav3 |
T |
C |
10: 109,688,795 (GRCm39) |
E494G |
possibly damaging |
Het |
| Nol10 |
T |
G |
12: 17,452,174 (GRCm39) |
V376G |
probably damaging |
Het |
| Oog2 |
A |
G |
4: 143,921,851 (GRCm39) |
K254E |
probably benign |
Het |
| Or10ac1 |
A |
G |
6: 42,515,662 (GRCm39) |
F98S |
possibly damaging |
Het |
| Or52z12 |
A |
T |
7: 103,233,588 (GRCm39) |
I120L |
possibly damaging |
Het |
| Or5b98 |
A |
G |
19: 12,931,811 (GRCm39) |
N286S |
probably damaging |
Het |
| Or5d41 |
A |
T |
2: 88,055,366 (GRCm39) |
Y3* |
probably null |
Het |
| Or5g25 |
T |
A |
2: 85,477,768 (GRCm39) |
D299V |
possibly damaging |
Het |
| Or5g27 |
A |
G |
2: 85,409,640 (GRCm39) |
D19G |
probably benign |
Het |
| Or6b1 |
T |
G |
6: 42,815,680 (GRCm39) |
Y288* |
probably null |
Het |
| Or6c6 |
A |
T |
10: 129,186,426 (GRCm39) |
|
probably benign |
Het |
| Or8h10 |
G |
A |
2: 86,808,501 (GRCm39) |
T213I |
probably benign |
Het |
| Osbpl11 |
T |
A |
16: 33,056,649 (GRCm39) |
D694E |
probably benign |
Het |
| Pcm1 |
T |
A |
8: 41,746,547 (GRCm39) |
Y1210N |
probably benign |
Het |
| Pdxk |
T |
C |
10: 78,276,697 (GRCm39) |
M293V |
probably benign |
Het |
| Plcb3 |
T |
C |
19: 6,940,235 (GRCm39) |
I451V |
probably benign |
Het |
| Plekhm2 |
A |
G |
4: 141,361,687 (GRCm39) |
F272S |
probably damaging |
Het |
| Pramel32 |
C |
A |
4: 88,546,202 (GRCm39) |
R380L |
probably benign |
Het |
| Ptgdr |
A |
T |
14: 45,095,689 (GRCm39) |
|
probably null |
Het |
| Ptprf |
C |
T |
4: 118,083,720 (GRCm39) |
V788I |
probably benign |
Het |
| Ralbp1 |
C |
T |
17: 66,161,143 (GRCm39) |
V467I |
probably benign |
Het |
| Ralgds |
A |
C |
2: 28,433,667 (GRCm39) |
Q229P |
possibly damaging |
Het |
| Recql |
T |
C |
6: 142,320,610 (GRCm39) |
D146G |
probably damaging |
Het |
| Reln |
T |
C |
5: 22,256,365 (GRCm39) |
N493S |
probably damaging |
Het |
| Rfxank |
C |
T |
8: 70,587,936 (GRCm39) |
|
probably null |
Het |
| Scn5a |
A |
T |
9: 119,315,596 (GRCm39) |
M1704K |
probably damaging |
Het |
| Slc7a7 |
G |
T |
14: 54,611,725 (GRCm39) |
A316E |
possibly damaging |
Het |
| Slco1a6 |
A |
T |
6: 142,036,794 (GRCm39) |
C538S |
probably benign |
Het |
| Stard6 |
T |
C |
18: 70,631,718 (GRCm39) |
|
probably null |
Het |
| Strip2 |
T |
A |
6: 29,927,612 (GRCm39) |
M219K |
possibly damaging |
Het |
| Tcam1 |
T |
C |
11: 106,174,911 (GRCm39) |
V122A |
probably damaging |
Het |
| Tha1 |
A |
G |
11: 117,760,516 (GRCm39) |
V236A |
possibly damaging |
Het |
| Tmem201 |
A |
T |
4: 149,815,554 (GRCm39) |
I132N |
possibly damaging |
Het |
| Tnc |
T |
C |
4: 63,938,894 (GRCm39) |
|
probably benign |
Het |
| Vmn1r42 |
T |
C |
6: 89,822,495 (GRCm39) |
T25A |
probably benign |
Het |
| Vmn2r94 |
T |
A |
17: 18,464,765 (GRCm39) |
|
probably null |
Het |
| Wdfy4 |
A |
C |
14: 32,790,863 (GRCm39) |
V2188G |
|
Het |
| Zfp623 |
T |
C |
15: 75,819,247 (GRCm39) |
S68P |
probably damaging |
Het |
| Zfp950 |
A |
T |
19: 61,107,593 (GRCm39) |
C497S |
probably damaging |
Het |
| Zkscan2 |
C |
T |
7: 123,079,327 (GRCm39) |
E877K |
probably damaging |
Het |
| Zp3r |
C |
A |
1: 130,504,790 (GRCm39) |
V536L |
probably damaging |
Het |
|
| Other mutations in Nup205 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00484:Nup205
|
APN |
6 |
35,191,737 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01086:Nup205
|
APN |
6 |
35,185,871 (GRCm39) |
splice site |
probably benign |
|
|
IGL01138:Nup205
|
APN |
6 |
35,185,019 (GRCm39) |
nonsense |
probably null |
|
|
IGL01333:Nup205
|
APN |
6 |
35,217,998 (GRCm39) |
missense |
probably benign |
|
|
IGL01399:Nup205
|
APN |
6 |
35,196,624 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL01466:Nup205
|
APN |
6 |
35,176,894 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01913:Nup205
|
APN |
6 |
35,204,365 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL02159:Nup205
|
APN |
6 |
35,166,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02442:Nup205
|
APN |
6 |
35,167,003 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02447:Nup205
|
APN |
6 |
35,204,511 (GRCm39) |
splice site |
probably null |
|
|
IGL02558:Nup205
|
APN |
6 |
35,166,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03306:Nup205
|
APN |
6 |
35,185,104 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03328:Nup205
|
APN |
6 |
35,209,349 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Figaro
|
UTSW |
6 |
35,173,649 (GRCm39) |
splice site |
probably null |
|
|
Marcellina
|
UTSW |
6 |
35,160,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Spirit
|
UTSW |
6 |
35,209,343 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Susanna
|
UTSW |
6 |
35,185,044 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
voyager
|
UTSW |
6 |
35,166,820 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
BB007:Nup205
|
UTSW |
6 |
35,171,511 (GRCm39) |
missense |
probably damaging |
0.98 |
|
BB017:Nup205
|
UTSW |
6 |
35,171,511 (GRCm39) |
missense |
probably damaging |
0.98 |
|
P0012:Nup205
|
UTSW |
6 |
35,173,478 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0102:Nup205
|
UTSW |
6 |
35,202,715 (GRCm39) |
splice site |
probably benign |
|
|
R0102:Nup205
|
UTSW |
6 |
35,202,715 (GRCm39) |
splice site |
probably benign |
|
|
R0362:Nup205
|
UTSW |
6 |
35,173,649 (GRCm39) |
splice site |
probably null |
|
|
R0374:Nup205
|
UTSW |
6 |
35,185,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0415:Nup205
|
UTSW |
6 |
35,191,569 (GRCm39) |
splice site |
probably benign |
|
|
R0427:Nup205
|
UTSW |
6 |
35,171,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0543:Nup205
|
UTSW |
6 |
35,175,904 (GRCm39) |
missense |
probably benign |
|
|
R0611:Nup205
|
UTSW |
6 |
35,202,903 (GRCm39) |
missense |
probably null |
1.00 |
|
R0761:Nup205
|
UTSW |
6 |
35,173,363 (GRCm39) |
splice site |
probably benign |
|
|
R0828:Nup205
|
UTSW |
6 |
35,171,501 (GRCm39) |
missense |
probably benign |
|
|
R0906:Nup205
|
UTSW |
6 |
35,213,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1023:Nup205
|
UTSW |
6 |
35,211,641 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1033:Nup205
|
UTSW |
6 |
35,204,377 (GRCm39) |
missense |
probably benign |
|
|
R1375:Nup205
|
UTSW |
6 |
35,177,006 (GRCm39) |
splice site |
probably benign |
|
|
R1447:Nup205
|
UTSW |
6 |
35,192,120 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1468:Nup205
|
UTSW |
6 |
35,202,917 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1468:Nup205
|
UTSW |
6 |
35,202,917 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1625:Nup205
|
UTSW |
6 |
35,168,878 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1652:Nup205
|
UTSW |
6 |
35,215,901 (GRCm39) |
missense |
probably benign |
|
|
R1659:Nup205
|
UTSW |
6 |
35,211,723 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1693:Nup205
|
UTSW |
6 |
35,187,906 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1769:Nup205
|
UTSW |
6 |
35,182,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1839:Nup205
|
UTSW |
6 |
35,196,649 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1959:Nup205
|
UTSW |
6 |
35,210,301 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2051:Nup205
|
UTSW |
6 |
35,207,451 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2267:Nup205
|
UTSW |
6 |
35,218,284 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R2401:Nup205
|
UTSW |
6 |
35,185,069 (GRCm39) |
nonsense |
probably null |
|
|
R3697:Nup205
|
UTSW |
6 |
35,165,646 (GRCm39) |
missense |
probably benign |
0.15 |
|
R3938:Nup205
|
UTSW |
6 |
35,196,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4074:Nup205
|
UTSW |
6 |
35,168,975 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4117:Nup205
|
UTSW |
6 |
35,217,947 (GRCm39) |
nonsense |
probably null |
|
|
R4364:Nup205
|
UTSW |
6 |
35,168,962 (GRCm39) |
missense |
probably benign |
0.38 |
|
R4366:Nup205
|
UTSW |
6 |
35,168,962 (GRCm39) |
missense |
probably benign |
0.38 |
|
R4594:Nup205
|
UTSW |
6 |
35,173,424 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4706:Nup205
|
UTSW |
6 |
35,178,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4787:Nup205
|
UTSW |
6 |
35,178,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4849:Nup205
|
UTSW |
6 |
35,207,505 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4850:Nup205
|
UTSW |
6 |
35,207,465 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4943:Nup205
|
UTSW |
6 |
35,201,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4966:Nup205
|
UTSW |
6 |
35,220,784 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5138:Nup205
|
UTSW |
6 |
35,202,801 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5251:Nup205
|
UTSW |
6 |
35,173,417 (GRCm39) |
splice site |
probably null |
|
|
R5444:Nup205
|
UTSW |
6 |
35,166,124 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5760:Nup205
|
UTSW |
6 |
35,224,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5762:Nup205
|
UTSW |
6 |
35,207,483 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5762:Nup205
|
UTSW |
6 |
35,204,615 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5941:Nup205
|
UTSW |
6 |
35,209,343 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5969:Nup205
|
UTSW |
6 |
35,154,513 (GRCm39) |
unclassified |
probably benign |
|
|
R6003:Nup205
|
UTSW |
6 |
35,189,751 (GRCm39) |
missense |
probably benign |
|
|
R6178:Nup205
|
UTSW |
6 |
35,220,778 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6315:Nup205
|
UTSW |
6 |
35,213,804 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6392:Nup205
|
UTSW |
6 |
35,166,820 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6710:Nup205
|
UTSW |
6 |
35,224,308 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6954:Nup205
|
UTSW |
6 |
35,185,044 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7022:Nup205
|
UTSW |
6 |
35,220,871 (GRCm39) |
missense |
probably benign |
0.45 |
|
R7041:Nup205
|
UTSW |
6 |
35,201,470 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R7052:Nup205
|
UTSW |
6 |
35,192,077 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7310:Nup205
|
UTSW |
6 |
35,202,904 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7363:Nup205
|
UTSW |
6 |
35,209,508 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7428:Nup205
|
UTSW |
6 |
35,204,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7553:Nup205
|
UTSW |
6 |
35,178,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7665:Nup205
|
UTSW |
6 |
35,154,555 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7841:Nup205
|
UTSW |
6 |
35,224,372 (GRCm39) |
missense |
unknown |
|
|
R7930:Nup205
|
UTSW |
6 |
35,171,511 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7973:Nup205
|
UTSW |
6 |
35,222,274 (GRCm39) |
missense |
probably benign |
|
|
R7976:Nup205
|
UTSW |
6 |
35,175,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8073:Nup205
|
UTSW |
6 |
35,179,104 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8080:Nup205
|
UTSW |
6 |
35,204,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8118:Nup205
|
UTSW |
6 |
35,207,451 (GRCm39) |
missense |
probably benign |
0.29 |
|
R8213:Nup205
|
UTSW |
6 |
35,202,138 (GRCm39) |
missense |
probably benign |
0.26 |
|
R8237:Nup205
|
UTSW |
6 |
35,204,438 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8408:Nup205
|
UTSW |
6 |
35,202,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8807:Nup205
|
UTSW |
6 |
35,160,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8812:Nup205
|
UTSW |
6 |
35,191,269 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9061:Nup205
|
UTSW |
6 |
35,196,808 (GRCm39) |
intron |
probably benign |
|
|
R9261:Nup205
|
UTSW |
6 |
35,176,792 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9403:Nup205
|
UTSW |
6 |
35,176,909 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9648:Nup205
|
UTSW |
6 |
35,202,746 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9744:Nup205
|
UTSW |
6 |
35,209,510 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9800:Nup205
|
UTSW |
6 |
35,163,468 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
Z1177:Nup205
|
UTSW |
6 |
35,185,728 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1177:Nup205
|
UTSW |
6 |
35,154,540 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CATGGCATAATGAGGAAAACCTTG -3'
(R):5'- CAGCAAACATGTTAAATAGTTGCCC -3'
Sequencing Primer
(F):5'- GCATAATGAGGAAAACCTTGAAACTC -3'
(R):5'- GCCCATGTGTGGTACAGCTATAC -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation