Mutagenetix > Incidental Mutation

Incidental Mutation 'R7608:Dnah11'

628165

Institutional Source

Beutler Lab

Gene Symbol

Dnah11

Ensembl Gene

ENSMUSG00000018581

Gene Name

dynein, axonemal, heavy chain 11

Synonyms

b2b598Clo, Dnahc11, b2b1289Clo, lrd, b2b1727Clo, b2b1203Clo, b2b1279Clo

MMRRC Submission

045678-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.492) question?

Stock #

R7608 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

117877982-118199043 bp(-) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

G to T at 118140770 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000081867 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000084806]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000084806

SMART Domains

Protein: ENSMUSP00000081867
Gene: ENSMUSG00000018581

Domain	Start	End	E-Value	Type
low complexity region	18	28	N/A	INTRINSIC
Pfam:DHC_N1	218	794	1.6e-162	PFAM
low complexity region	1266	1282	N/A	INTRINSIC
Pfam:DHC_N2	1297	1705	1e-130	PFAM
low complexity region	1757	1773	N/A	INTRINSIC
AAA	1869	1963	1.51e0	SMART
Pfam:AAA_5	2150	2286	1.6e-12	PFAM
AAA	2474	2619	1.48e-1	SMART
AAA	2819	2931	4.57e-1	SMART
Pfam:MT	3069	3413	3.2e-162	PFAM
Pfam:AAA_9	3434	3656	2.9e-88	PFAM
Pfam:Dynein_heavy	3790	4486	7.1e-235	PFAM

Meta Mutation Damage Score

0.9755

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.1%

Validation Efficiency

100% (51/51)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a ciliary outer dynein arm protein and is a member of the dynein heavy chain family. It is a microtubule-dependent motor ATPase and has been reported to be involved in the movement of respiratory cilia. Mutations in this gene have been implicated in causing Kartagener Syndrome (a combination of situs inversus totalis and Primary Ciliary Dyskinesia (PCD), also called Immotile Cilia Syndrome 1 (ICS1)) and male sterility. [provided by RefSeq, Mar 2013]
PHENOTYPE: Approximately half of live-born homozygous mutants show situs inversus indicating that this gene is no longer properly controlling left-right asymmetry. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 50 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb6	A	G	1: 75,177,703 (GRCm38)	F311S	probably benign	Het
Adamts7	C	A	9: 90,173,773 (GRCm38)	T193N	possibly damaging	Het
Akr1b7	A	G	6: 34,420,522 (GRCm38)	N273S	probably damaging	Het
Asz1	G	A	6: 18,077,253 (GRCm38)	T151M	probably damaging	Het
Atrnl1	T	A	19: 57,714,687 (GRCm38)	Y1046N	probably damaging	Het
Cacna2d1	T	C	5: 16,359,024 (GRCm38)	S902P	probably damaging	Het
Casp3	T	A	8: 46,634,333 (GRCm38)	I105K	probably benign	Het
Ccdc146	C	T	5: 21,301,452 (GRCm38)	V664I	probably benign	Het
Cfap61	G	A	2: 145,963,531 (GRCm38)	C267Y	possibly damaging	Het
Dgkz	A	T	2: 91,934,054 (GRCm38)		probably null	Het
Duox1	C	A	2: 122,326,135 (GRCm38)	Y514*	probably null	Het
Epha7	C	T	4: 28,871,937 (GRCm38)	S422L	probably benign	Het
Fam214b	A	G	4: 43,036,533 (GRCm38)	L66P	probably damaging	Het
Fan1	A	T	7: 64,354,231 (GRCm38)		probably null	Het
Fgfrl1	A	T	5: 108,705,345 (GRCm38)	K278M	probably damaging	Het
Fign	T	C	2: 63,978,719 (GRCm38)	I736V	possibly damaging	Het
Galns	A	G	8: 122,591,445 (GRCm38)	F410S	probably benign	Het
Hspbp1	C	A	7: 4,660,822 (GRCm38)	K341N	possibly damaging	Het
Idh3b	A	T	2: 130,280,980 (GRCm38)	S296R	probably damaging	Het
Ifi44	A	G	3: 151,732,408 (GRCm38)	F414S	probably damaging	Het
Kdm3a	T	A	6: 71,600,747 (GRCm38)	M690L	probably benign	Het
Lrrc49	C	T	9: 60,602,722 (GRCm38)	G488S	probably null	Het
Mcc	T	C	18: 44,491,227 (GRCm38)	N417S	possibly damaging	Het
Melk	T	A	4: 44,325,571 (GRCm38)		probably null	Het
Mtcl1	T	C	17: 66,343,305 (GRCm38)	R1722G	probably damaging	Het
Olfr1252	A	G	2: 89,721,298 (GRCm38)	V271A	probably benign	Het
Olfr1475	G	A	19: 13,479,592 (GRCm38)	T202I	possibly damaging	Het
Olfr562-ps1	A	G	7: 102,781,925 (GRCm38)	I150V	probably benign	Het
Olfr924	T	A	9: 38,848,510 (GRCm38)	V132D	possibly damaging	Het
Pdzrn3	T	C	6: 101,151,752 (GRCm38)	E651G	probably damaging	Het
Pop5	A	G	5: 115,237,872 (GRCm38)		probably benign	Het
Prox1	T	A	1: 190,153,445 (GRCm38)	M602L	probably benign	Het
Prpf39	G	A	12: 65,053,446 (GRCm38)	A298T	probably benign	Het
Scg2	T	C	1: 79,436,181 (GRCm38)	E275G	probably benign	Het
Scn11a	A	T	9: 119,815,313 (GRCm38)		probably null	Het
Slc16a4	A	T	3: 107,303,127 (GRCm38)	Y371F	probably damaging	Het
Slc4a1ap	T	A	5: 31,536,189 (GRCm38)	M489K	possibly damaging	Het
Spata13	A	G	14: 60,692,507 (GRCm38)	N505D	possibly damaging	Het
Tas2r129	A	G	6: 132,951,193 (GRCm38)	N31S	probably damaging	Het
Tmem159	A	G	7: 120,104,788 (GRCm38)	K19E	probably damaging	Het
Tnn	A	T	1: 160,088,414 (GRCm38)	Y1508*	probably null	Het
Trim23	T	C	13: 104,192,033 (GRCm38)	V354A	probably benign	Het
Tsc1	A	T	2: 28,658,736 (GRCm38)	T18S	probably benign	Het
Txlnb	A	G	10: 17,815,398 (GRCm38)	K232R	probably damaging	Het
Vmn1r53	C	T	6: 90,224,122 (GRCm38)	M73I	probably benign	Het
Vmn1r67	G	A	7: 10,447,363 (GRCm38)	V185M	possibly damaging	Het
Vmn2r14	A	G	5: 109,221,410 (GRCm38)	I99T	probably benign	Het
Zfp318	T	G	17: 46,400,009 (GRCm38)	V886G	probably damaging	Het
Zfp760	A	G	17: 21,722,816 (GRCm38)	N324S	probably benign	Het
Zfp819	T	C	7: 43,616,933 (GRCm38)	V280A	probably benign	Het

Other mutations in Dnah11

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00341:Dnah11	APN	12	118,198,745 (GRCm38)	missense	probably benign	0.28
IGL00422:Dnah11	APN	12	118,068,096 (GRCm38)	missense	probably damaging	1.00
IGL00436:Dnah11	APN	12	118,036,459 (GRCm38)	missense	possibly damaging	0.56
IGL00540:Dnah11	APN	12	118,186,922 (GRCm38)	missense	probably benign	0.01
IGL00687:Dnah11	APN	12	117,922,004 (GRCm38)	splice site	probably benign
IGL00833:Dnah11	APN	12	118,179,580 (GRCm38)	missense	probably damaging	1.00
IGL00906:Dnah11	APN	12	117,911,202 (GRCm38)	missense	probably damaging	1.00
IGL00952:Dnah11	APN	12	118,196,651 (GRCm38)	missense	possibly damaging	0.56
IGL01111:Dnah11	APN	12	118,142,934 (GRCm38)	splice site	probably benign
IGL01121:Dnah11	APN	12	118,050,695 (GRCm38)	missense	probably benign	0.02
IGL01143:Dnah11	APN	12	118,012,740 (GRCm38)	missense	probably damaging	1.00
IGL01359:Dnah11	APN	12	117,982,999 (GRCm38)	missense	probably damaging	0.99
IGL01372:Dnah11	APN	12	118,192,399 (GRCm38)	missense	probably damaging	1.00
IGL01410:Dnah11	APN	12	118,047,256 (GRCm38)	nonsense	probably null
IGL01418:Dnah11	APN	12	117,987,482 (GRCm38)	nonsense	probably null
IGL01444:Dnah11	APN	12	118,020,232 (GRCm38)	missense	possibly damaging	0.91
IGL01606:Dnah11	APN	12	117,983,032 (GRCm38)	missense	probably benign	0.15
IGL01645:Dnah11	APN	12	118,186,998 (GRCm38)	missense	possibly damaging	0.90
IGL01932:Dnah11	APN	12	118,192,270 (GRCm38)	splice site	probably benign
IGL02104:Dnah11	APN	12	118,192,390 (GRCm38)	missense	probably benign
IGL02151:Dnah11	APN	12	118,059,888 (GRCm38)	splice site	probably benign
IGL02189:Dnah11	APN	12	118,082,579 (GRCm38)	missense	probably benign	0.00
IGL02417:Dnah11	APN	12	118,057,180 (GRCm38)	missense	probably damaging	1.00
IGL02421:Dnah11	APN	12	118,186,902 (GRCm38)	missense	probably damaging	1.00
IGL02444:Dnah11	APN	12	117,975,873 (GRCm38)	splice site	probably benign
IGL02474:Dnah11	APN	12	118,027,445 (GRCm38)	splice site	probably null
IGL02526:Dnah11	APN	12	118,179,618 (GRCm38)	missense	possibly damaging	0.70
IGL02887:Dnah11	APN	12	117,911,040 (GRCm38)	missense	probably damaging	1.00
IGL03011:Dnah11	APN	12	118,012,377 (GRCm38)	missense	probably benign	0.08
IGL03061:Dnah11	APN	12	117,903,121 (GRCm38)	missense	probably damaging	1.00
IGL03182:Dnah11	APN	12	118,030,291 (GRCm38)	missense	probably damaging	0.99
IGL03220:Dnah11	APN	12	118,105,985 (GRCm38)	missense	probably benign
IGL03238:Dnah11	APN	12	118,109,898 (GRCm38)	missense	probably damaging	1.00
IGL03493:Dnah11	APN	12	118,012,798 (GRCm38)	missense	probably benign	0.00
P0045:Dnah11	UTSW	12	118,030,327 (GRCm38)	missense	probably benign
R0009:Dnah11	UTSW	12	118,045,522 (GRCm38)	missense	possibly damaging	0.90
R0066:Dnah11	UTSW	12	118,126,886 (GRCm38)	missense	probably benign	0.05
R0172:Dnah11	UTSW	12	117,987,453 (GRCm38)	missense	probably damaging	1.00
R0206:Dnah11	UTSW	12	118,043,774 (GRCm38)	missense	probably damaging	0.98
R0206:Dnah11	UTSW	12	118,043,774 (GRCm38)	missense	probably damaging	0.98
R0208:Dnah11	UTSW	12	118,043,774 (GRCm38)	missense	probably damaging	0.98
R0230:Dnah11	UTSW	12	117,983,056 (GRCm38)	nonsense	probably null
R0270:Dnah11	UTSW	12	118,041,013 (GRCm38)	missense	probably damaging	1.00
R0311:Dnah11	UTSW	12	118,127,133 (GRCm38)	missense	probably benign	0.03
R0325:Dnah11	UTSW	12	118,012,339 (GRCm38)	missense	probably benign
R0370:Dnah11	UTSW	12	117,995,227 (GRCm38)	missense	probably benign
R0416:Dnah11	UTSW	12	117,911,058 (GRCm38)	missense	probably damaging	1.00
R0505:Dnah11	UTSW	12	118,106,510 (GRCm38)	missense	probably damaging	1.00
R0540:Dnah11	UTSW	12	118,082,511 (GRCm38)	missense	probably damaging	1.00
R0554:Dnah11	UTSW	12	117,931,178 (GRCm38)	missense	probably benign	0.01
R0607:Dnah11	UTSW	12	118,082,511 (GRCm38)	missense	probably damaging	1.00
R0620:Dnah11	UTSW	12	117,987,469 (GRCm38)	missense	probably damaging	1.00
R0635:Dnah11	UTSW	12	118,007,996 (GRCm38)	missense	probably damaging	1.00
R0755:Dnah11	UTSW	12	118,198,625 (GRCm38)	missense	probably benign	0.17
R0755:Dnah11	UTSW	12	117,954,829 (GRCm38)	missense	possibly damaging	0.95
R0789:Dnah11	UTSW	12	117,911,232 (GRCm38)	missense	probably damaging	1.00
R0833:Dnah11	UTSW	12	118,196,662 (GRCm38)	missense	probably benign	0.01
R0835:Dnah11	UTSW	12	117,916,788 (GRCm38)	missense	probably damaging	1.00
R0836:Dnah11	UTSW	12	118,196,662 (GRCm38)	missense	probably benign	0.01
R0846:Dnah11	UTSW	12	117,933,850 (GRCm38)	missense	probably damaging	0.97
R0865:Dnah11	UTSW	12	118,190,844 (GRCm38)	nonsense	probably null
R0928:Dnah11	UTSW	12	118,045,562 (GRCm38)	missense	probably damaging	1.00
R0939:Dnah11	UTSW	12	118,060,407 (GRCm38)	missense	probably damaging	1.00
R1203:Dnah11	UTSW	12	117,933,812 (GRCm38)	missense	possibly damaging	0.81
R1394:Dnah11	UTSW	12	117,972,364 (GRCm38)	missense	possibly damaging	0.75
R1398:Dnah11	UTSW	12	118,057,106 (GRCm38)	nonsense	probably null
R1465:Dnah11	UTSW	12	118,038,695 (GRCm38)	missense	probably damaging	1.00
R1465:Dnah11	UTSW	12	118,038,695 (GRCm38)	missense	probably damaging	1.00
R1500:Dnah11	UTSW	12	118,012,829 (GRCm38)	splice site	probably null
R1535:Dnah11	UTSW	12	118,018,730 (GRCm38)	missense	probably damaging	1.00
R1539:Dnah11	UTSW	12	117,931,256 (GRCm38)	missense	probably benign	0.01
R1554:Dnah11	UTSW	12	118,082,499 (GRCm38)	missense	possibly damaging	0.92
R1574:Dnah11	UTSW	12	118,060,317 (GRCm38)	missense	probably damaging	1.00
R1574:Dnah11	UTSW	12	118,060,317 (GRCm38)	missense	probably damaging	1.00
R1615:Dnah11	UTSW	12	118,050,722 (GRCm38)	missense	probably damaging	1.00
R1618:Dnah11	UTSW	12	118,015,465 (GRCm38)	missense	probably damaging	0.98
R1638:Dnah11	UTSW	12	118,015,419 (GRCm38)	missense	possibly damaging	0.81
R1659:Dnah11	UTSW	12	118,120,724 (GRCm38)	missense	possibly damaging	0.94
R1671:Dnah11	UTSW	12	117,916,788 (GRCm38)	missense	probably damaging	1.00
R1678:Dnah11	UTSW	12	117,933,845 (GRCm38)	missense	possibly damaging	0.50
R1699:Dnah11	UTSW	12	118,190,868 (GRCm38)	missense	probably damaging	1.00
R1712:Dnah11	UTSW	12	118,196,644 (GRCm38)	missense	probably benign	0.32
R1728:Dnah11	UTSW	12	117,916,931 (GRCm38)	missense	probably damaging	1.00
R1729:Dnah11	UTSW	12	117,916,931 (GRCm38)	missense	probably damaging	1.00
R1764:Dnah11	UTSW	12	118,190,825 (GRCm38)	missense	probably benign	0.31
R1780:Dnah11	UTSW	12	118,027,558 (GRCm38)	missense	probably damaging	1.00
R1789:Dnah11	UTSW	12	118,038,780 (GRCm38)	missense	probably damaging	0.99
R1800:Dnah11	UTSW	12	117,916,788 (GRCm38)	missense	probably damaging	1.00
R1863:Dnah11	UTSW	12	118,063,852 (GRCm38)	missense	possibly damaging	0.92
R1892:Dnah11	UTSW	12	118,106,474 (GRCm38)	missense	possibly damaging	0.53
R1907:Dnah11	UTSW	12	118,127,556 (GRCm38)	missense	possibly damaging	0.66
R1964:Dnah11	UTSW	12	118,142,292 (GRCm38)	missense	possibly damaging	0.56
R1967:Dnah11	UTSW	12	117,916,788 (GRCm38)	missense	probably damaging	1.00
R1997:Dnah11	UTSW	12	118,082,468 (GRCm38)	missense	possibly damaging	0.64
R2086:Dnah11	UTSW	12	118,113,871 (GRCm38)	missense	possibly damaging	0.82
R2092:Dnah11	UTSW	12	118,012,716 (GRCm38)	missense	possibly damaging	0.50
R2108:Dnah11	UTSW	12	118,020,353 (GRCm38)	missense	probably damaging	1.00
R2140:Dnah11	UTSW	12	118,008,810 (GRCm38)	missense	probably benign	0.01
R2261:Dnah11	UTSW	12	117,966,639 (GRCm38)	missense	probably damaging	0.99
R2261:Dnah11	UTSW	12	117,880,025 (GRCm38)	missense	probably benign	0.06
R2262:Dnah11	UTSW	12	117,966,639 (GRCm38)	missense	probably damaging	0.99
R2262:Dnah11	UTSW	12	117,880,025 (GRCm38)	missense	probably benign	0.06
R2263:Dnah11	UTSW	12	117,880,025 (GRCm38)	missense	probably benign	0.06
R2263:Dnah11	UTSW	12	117,966,639 (GRCm38)	missense	probably damaging	0.99
R2328:Dnah11	UTSW	12	117,886,686 (GRCm38)	missense	probably damaging	0.98
R2352:Dnah11	UTSW	12	117,928,330 (GRCm38)	missense	probably damaging	1.00
R2410:Dnah11	UTSW	12	118,027,527 (GRCm38)	missense	probably damaging	1.00
R2885:Dnah11	UTSW	12	117,987,427 (GRCm38)	nonsense	probably null
R3499:Dnah11	UTSW	12	117,911,023 (GRCm38)	missense	probably damaging	1.00
R3741:Dnah11	UTSW	12	118,131,341 (GRCm38)	missense	probably benign	0.05
R3742:Dnah11	UTSW	12	118,131,341 (GRCm38)	missense	probably benign	0.05
R3779:Dnah11	UTSW	12	118,130,713 (GRCm38)	splice site	probably benign
R3785:Dnah11	UTSW	12	118,017,602 (GRCm38)	missense	probably damaging	1.00
R3883:Dnah11	UTSW	12	117,978,453 (GRCm38)	splice site	probably benign
R4014:Dnah11	UTSW	12	117,974,914 (GRCm38)	missense	probably benign	0.16
R4043:Dnah11	UTSW	12	117,879,943 (GRCm38)	missense	probably damaging	1.00
R4072:Dnah11	UTSW	12	118,106,492 (GRCm38)	missense	probably damaging	1.00
R4073:Dnah11	UTSW	12	118,045,678 (GRCm38)	missense	probably benign	0.01
R4074:Dnah11	UTSW	12	118,045,678 (GRCm38)	missense	probably benign	0.01
R4076:Dnah11	UTSW	12	118,045,678 (GRCm38)	missense	probably benign	0.01
R4201:Dnah11	UTSW	12	117,966,659 (GRCm38)	missense	possibly damaging	0.63
R4224:Dnah11	UTSW	12	118,130,892 (GRCm38)	missense	probably benign	0.06
R4233:Dnah11	UTSW	12	117,916,791 (GRCm38)	missense	probably damaging	1.00
R4358:Dnah11	UTSW	12	118,125,843 (GRCm38)	nonsense	probably null
R4430:Dnah11	UTSW	12	117,983,011 (GRCm38)	missense	probably benign	0.26
R4465:Dnah11	UTSW	12	117,987,451 (GRCm38)	missense	probably benign	0.09
R4489:Dnah11	UTSW	12	117,916,896 (GRCm38)	missense	probably benign	0.31
R4572:Dnah11	UTSW	12	118,010,125 (GRCm38)	missense	probably benign	0.00
R4574:Dnah11	UTSW	12	118,012,255 (GRCm38)	critical splice donor site	probably null
R4657:Dnah11	UTSW	12	118,192,427 (GRCm38)	missense	probably benign	0.02
R4709:Dnah11	UTSW	12	118,018,760 (GRCm38)	missense	probably benign	0.26
R4740:Dnah11	UTSW	12	118,120,544 (GRCm38)	missense	probably benign	0.28
R4803:Dnah11	UTSW	12	118,127,608 (GRCm38)	missense	possibly damaging	0.50
R4896:Dnah11	UTSW	12	117,995,200 (GRCm38)	missense	probably damaging	1.00
R4908:Dnah11	UTSW	12	118,126,883 (GRCm38)	missense	probably benign	0.37
R5018:Dnah11	UTSW	12	118,130,728 (GRCm38)	missense	probably benign	0.00
R5071:Dnah11	UTSW	12	118,082,453 (GRCm38)	nonsense	probably null
R5074:Dnah11	UTSW	12	118,082,453 (GRCm38)	nonsense	probably null
R5080:Dnah11	UTSW	12	118,198,830 (GRCm38)	start codon destroyed	probably null	0.01
R5097:Dnah11	UTSW	12	118,017,700 (GRCm38)	missense	probably damaging	1.00
R5131:Dnah11	UTSW	12	117,954,751 (GRCm38)	missense	probably damaging	1.00
R5215:Dnah11	UTSW	12	118,157,361 (GRCm38)	missense	probably benign	0.09
R5252:Dnah11	UTSW	12	118,125,941 (GRCm38)	missense	probably damaging	1.00
R5296:Dnah11	UTSW	12	117,883,416 (GRCm38)	missense	probably damaging	1.00
R5308:Dnah11	UTSW	12	118,085,680 (GRCm38)	missense	possibly damaging	0.60
R5368:Dnah11	UTSW	12	117,954,893 (GRCm38)	missense	probably damaging	1.00
R5383:Dnah11	UTSW	12	118,085,697 (GRCm38)	missense	probably damaging	0.99
R5499:Dnah11	UTSW	12	118,106,474 (GRCm38)	missense	possibly damaging	0.53
R5503:Dnah11	UTSW	12	117,880,451 (GRCm38)	critical splice donor site	probably null
R5546:Dnah11	UTSW	12	117,975,848 (GRCm38)	missense	possibly damaging	0.83
R5578:Dnah11	UTSW	12	118,018,802 (GRCm38)	missense	probably damaging	0.99
R5657:Dnah11	UTSW	12	117,883,617 (GRCm38)	missense	probably damaging	1.00
R5702:Dnah11	UTSW	12	118,113,907 (GRCm38)	missense	probably benign	0.04
R5706:Dnah11	UTSW	12	118,023,935 (GRCm38)	missense	probably damaging	1.00
R5727:Dnah11	UTSW	12	118,127,106 (GRCm38)	missense	probably damaging	1.00
R5737:Dnah11	UTSW	12	118,192,390 (GRCm38)	missense	probably benign
R5884:Dnah11	UTSW	12	118,177,534 (GRCm38)	missense	probably benign	0.00
R5900:Dnah11	UTSW	12	118,082,431 (GRCm38)	splice site	probably null
R5905:Dnah11	UTSW	12	117,954,924 (GRCm38)	missense	probably damaging	1.00
R5928:Dnah11	UTSW	12	117,914,636 (GRCm38)	splice site	probably null
R5973:Dnah11	UTSW	12	118,110,952 (GRCm38)	missense	probably benign	0.02
R6024:Dnah11	UTSW	12	118,030,272 (GRCm38)	missense	probably benign	0.34
R6056:Dnah11	UTSW	12	117,928,456 (GRCm38)	missense	probably benign	0.03
R6075:Dnah11	UTSW	12	118,104,851 (GRCm38)	missense	probably damaging	1.00
R6092:Dnah11	UTSW	12	117,928,456 (GRCm38)	missense	probably benign
R6191:Dnah11	UTSW	12	118,190,897 (GRCm38)	missense	probably benign
R6197:Dnah11	UTSW	12	118,179,747 (GRCm38)	missense	probably benign	0.03
R6262:Dnah11	UTSW	12	117,931,178 (GRCm38)	missense	probably damaging	0.98
R6321:Dnah11	UTSW	12	118,142,292 (GRCm38)	missense	possibly damaging	0.56
R6454:Dnah11	UTSW	12	117,916,855 (GRCm38)	missense	probably benign	0.01
R6614:Dnah11	UTSW	12	117,886,676 (GRCm38)	missense	possibly damaging	0.72
R6694:Dnah11	UTSW	12	118,186,882 (GRCm38)	splice site	probably null
R6712:Dnah11	UTSW	12	118,050,722 (GRCm38)	missense	probably damaging	1.00
R6720:Dnah11	UTSW	12	118,045,646 (GRCm38)	missense	probably damaging	1.00
R6742:Dnah11	UTSW	12	118,113,894 (GRCm38)	missense	possibly damaging	0.82
R6806:Dnah11	UTSW	12	117,987,676 (GRCm38)	splice site	probably null
R6895:Dnah11	UTSW	12	117,995,191 (GRCm38)	missense	probably damaging	0.99
R6939:Dnah11	UTSW	12	118,106,562 (GRCm38)	missense	probably damaging	1.00
R6940:Dnah11	UTSW	12	118,198,768 (GRCm38)	missense	probably benign
R6945:Dnah11	UTSW	12	118,060,310 (GRCm38)	missense	probably damaging	1.00
R6958:Dnah11	UTSW	12	117,933,809 (GRCm38)	missense	probably damaging	1.00
R6970:Dnah11	UTSW	12	118,108,944 (GRCm38)	missense	probably benign	0.00
R6976:Dnah11	UTSW	12	118,198,643 (GRCm38)	missense	probably benign	0.16
R7000:Dnah11	UTSW	12	118,017,661 (GRCm38)	missense	probably damaging	1.00
R7011:Dnah11	UTSW	12	117,922,018 (GRCm38)	frame shift	probably null
R7101:Dnah11	UTSW	12	118,068,145 (GRCm38)	missense	probably benign
R7106:Dnah11	UTSW	12	117,961,149 (GRCm38)	missense	probably benign	0.15
R7203:Dnah11	UTSW	12	118,045,522 (GRCm38)	missense	possibly damaging	0.90
R7219:Dnah11	UTSW	12	118,126,889 (GRCm38)	missense	probably benign	0.00
R7219:Dnah11	UTSW	12	118,041,095 (GRCm38)	missense	possibly damaging	0.95
R7308:Dnah11	UTSW	12	117,995,275 (GRCm38)	missense	probably damaging	1.00
R7361:Dnah11	UTSW	12	118,018,742 (GRCm38)	missense	probably damaging	1.00
R7367:Dnah11	UTSW	12	117,987,442 (GRCm38)	missense	possibly damaging	0.59
R7399:Dnah11	UTSW	12	118,125,785 (GRCm38)	missense	probably damaging	1.00
R7399:Dnah11	UTSW	12	118,027,477 (GRCm38)	missense	probably benign	0.00
R7404:Dnah11	UTSW	12	118,104,808 (GRCm38)	missense	probably benign	0.36
R7473:Dnah11	UTSW	12	117,903,176 (GRCm38)	missense	probably benign	0.19
R7545:Dnah11	UTSW	12	117,931,204 (GRCm38)	missense	probably damaging	1.00
R7625:Dnah11	UTSW	12	118,196,642 (GRCm38)	missense	probably benign
R7761:Dnah11	UTSW	12	118,023,913 (GRCm38)	missense	probably damaging	1.00
R7879:Dnah11	UTSW	12	118,041,009 (GRCm38)	missense	probably damaging	1.00
R7881:Dnah11	UTSW	12	117,987,502 (GRCm38)	missense	probably benign	0.04
R7904:Dnah11	UTSW	12	117,903,268 (GRCm38)	missense	possibly damaging	0.72
R8100:Dnah11	UTSW	12	117,966,633 (GRCm38)	missense	probably damaging	0.99
R8179:Dnah11	UTSW	12	117,878,549 (GRCm38)	missense	possibly damaging	0.90
R8192:Dnah11	UTSW	12	118,012,446 (GRCm38)	missense	probably benign
R8254:Dnah11	UTSW	12	117,878,524 (GRCm38)	missense	possibly damaging	0.89
R8268:Dnah11	UTSW	12	118,027,508 (GRCm38)	nonsense	probably null
R8272:Dnah11	UTSW	12	118,111,017 (GRCm38)	missense	probably benign	0.01
R8344:Dnah11	UTSW	12	118,085,731 (GRCm38)	missense	probably benign	0.00
R8515:Dnah11	UTSW	12	117,975,798 (GRCm38)	missense	probably damaging	1.00
R8528:Dnah11	UTSW	12	118,008,803 (GRCm38)	missense	probably damaging	0.96
R8557:Dnah11	UTSW	12	117,878,512 (GRCm38)	missense	probably benign
R8676:Dnah11	UTSW	12	118,190,804 (GRCm38)	missense	probably damaging	1.00
R8738:Dnah11	UTSW	12	118,085,649 (GRCm38)	critical splice donor site	probably null
R8773:Dnah11	UTSW	12	117,995,215 (GRCm38)	missense	possibly damaging	0.94
R8818:Dnah11	UTSW	12	117,911,029 (GRCm38)	missense	probably damaging	1.00
R8855:Dnah11	UTSW	12	118,192,372 (GRCm38)	missense	probably benign	0.03
R8866:Dnah11	UTSW	12	118,192,372 (GRCm38)	missense	probably benign	0.03
R8881:Dnah11	UTSW	12	118,126,815 (GRCm38)	missense	probably benign	0.05
R8881:Dnah11	UTSW	12	118,113,912 (GRCm38)	missense	probably benign	0.00
R8920:Dnah11	UTSW	12	118,113,939 (GRCm38)	missense	probably damaging	0.99
R8944:Dnah11	UTSW	12	118,127,646 (GRCm38)	missense	possibly damaging	0.63
R8945:Dnah11	UTSW	12	118,023,983 (GRCm38)	missense	probably benign	0.36
R8962:Dnah11	UTSW	12	117,954,895 (GRCm38)	missense	probably damaging	1.00
R8962:Dnah11	UTSW	12	117,952,538 (GRCm38)	missense	probably damaging	1.00
R9059:Dnah11	UTSW	12	118,130,843 (GRCm38)	missense	probably benign	0.00
R9155:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9162:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9164:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9171:Dnah11	UTSW	12	117,931,183 (GRCm38)	missense	probably damaging	0.99
R9186:Dnah11	UTSW	12	118,190,897 (GRCm38)	missense	probably benign
R9205:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9208:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9234:Dnah11	UTSW	12	117,987,360 (GRCm38)	missense	probably damaging	1.00
R9264:Dnah11	UTSW	12	118,027,527 (GRCm38)	missense	probably damaging	1.00
R9290:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9291:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9315:Dnah11	UTSW	12	118,179,606 (GRCm38)	missense	probably benign	0.11
R9353:Dnah11	UTSW	12	118,179,699 (GRCm38)	missense	probably benign	0.00
R9375:Dnah11	UTSW	12	117,920,968 (GRCm38)	missense	possibly damaging	0.67
R9392:Dnah11	UTSW	12	118,177,555 (GRCm38)	missense	probably benign	0.00
R9392:Dnah11	UTSW	12	118,047,320 (GRCm38)	nonsense	probably null
R9433:Dnah11	UTSW	12	118,012,272 (GRCm38)	missense	probably damaging	1.00
R9511:Dnah11	UTSW	12	117,914,617 (GRCm38)	missense	probably damaging	1.00
R9526:Dnah11	UTSW	12	118,186,976 (GRCm38)	missense	probably damaging	0.98
R9566:Dnah11	UTSW	12	117,974,993 (GRCm38)	missense	possibly damaging	0.69
R9673:Dnah11	UTSW	12	118,018,778 (GRCm38)	missense	possibly damaging	0.91
R9705:Dnah11	UTSW	12	118,131,035 (GRCm38)	missense	probably damaging	1.00
R9716:Dnah11	UTSW	12	118,060,413 (GRCm38)	missense	probably damaging	0.99
R9746:Dnah11	UTSW	12	117,878,576 (GRCm38)	nonsense	probably null
R9764:Dnah11	UTSW	12	117,920,969 (GRCm38)	missense	probably benign	0.05
RF023:Dnah11	UTSW	12	117,954,850 (GRCm38)	missense	probably damaging	1.00
RF047:Dnah11	UTSW	12	118,010,083 (GRCm38)	missense	probably damaging	1.00
Z1088:Dnah11	UTSW	12	117,895,012 (GRCm38)	missense	probably damaging	1.00
Z1088:Dnah11	UTSW	12	117,982,969 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah11	UTSW	12	118,130,799 (GRCm38)	missense	probably damaging	0.97
Z1176:Dnah11	UTSW	12	118,127,119 (GRCm38)	missense	probably benign	0.00
Z1176:Dnah11	UTSW	12	117,931,177 (GRCm38)	missense	possibly damaging	0.81

Predicted Primers

PCR Primer
(F):5'- GGCCGTTTATGGGACTGAATTTAAC -3'
(R):5'- ATGTAGGCAGGGCAGATTTG -3'

Sequencing Primer
(F):5'- TTATGGGACTGAATTTAACCAAGGG -3'
(R):5'- TGAAAGTCCCTCCTGGCTACAG -3'

Posted On

2020-01-28