Incidental Mutation 'R7699:Dip2c'
| ID |
593880 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dip2c
|
| Ensembl Gene |
ENSMUSG00000048264 |
| Gene Name |
disco interacting protein 2 homolog C |
| Synonyms |
2900024P20Rik |
| MMRRC Submission |
045760-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.589)
|
| Stock # |
R7699 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
9326564-9718964 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 9709347 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Alanine
at position 1396
(S1396A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133806
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000166299]
[ENSMUST00000169960]
[ENSMUST00000174552]
|
| AlphaFold |
E9PWR4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000166299
AA Change: S1397A
PolyPhen 2
Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)
|
| SMART Domains |
Protein: ENSMUSP00000126827
Gene: ENSMUSG00000048264
AA Change: S1397A
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
120 |
3.55e-43 |
SMART |
|
low complexity region
|
170 |
187 |
N/A |
INTRINSIC |
|
low complexity region
|
275 |
287 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
324 |
801 |
3.6e-23 |
PFAM |
|
Pfam:AMP-binding
|
977 |
1451 |
1.5e-72 |
PFAM |
|
low complexity region
|
1514 |
1526 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000169960
AA Change: S1367A
PolyPhen 2
Score 0.684 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000131238
Gene: ENSMUSG00000048264
AA Change: S1367A
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
176 |
3.02e-37 |
SMART |
|
low complexity region
|
226 |
243 |
N/A |
INTRINSIC |
|
low complexity region
|
331 |
343 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
380 |
637 |
5.9e-10 |
PFAM |
|
SCOP:d1lci__
|
675 |
875 |
2e-8 |
SMART |
|
Pfam:AMP-binding
|
947 |
1421 |
1.2e-56 |
PFAM |
|
low complexity region
|
1484 |
1496 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000174552
AA Change: S1396A
PolyPhen 2
Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)
|
| SMART Domains |
Protein: ENSMUSP00000133806
Gene: ENSMUSG00000048264
AA Change: S1396A
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
120 |
3.55e-43 |
SMART |
|
low complexity region
|
170 |
187 |
N/A |
INTRINSIC |
|
low complexity region
|
275 |
287 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
324 |
800 |
2.7e-20 |
PFAM |
|
Pfam:AMP-binding
|
976 |
1450 |
1.3e-56 |
PFAM |
|
low complexity region
|
1513 |
1525 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| Meta Mutation Damage Score |
0.0707 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the disco-interacting protein homolog 2 family. The protein shares strong similarity with a Drosophila protein which interacts with the transcription factor disco and is expressed in the nervous system. [provided by RefSeq, Oct 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1810009A15Rik |
T |
C |
19: 8,867,417 (GRCm39) |
L72P |
probably benign |
Het |
| 4930407I10Rik |
C |
A |
15: 81,948,306 (GRCm39) |
H734Q |
probably benign |
Het |
| Acadl |
A |
G |
1: 66,877,522 (GRCm39) |
V343A |
possibly damaging |
Het |
| Acot4 |
A |
T |
12: 84,090,011 (GRCm39) |
D236V |
probably damaging |
Het |
| App |
T |
A |
16: 84,837,197 (GRCm39) |
|
probably null |
Het |
| Arfgef1 |
G |
A |
1: 10,264,636 (GRCm39) |
T470I |
possibly damaging |
Het |
| Arhgef5 |
T |
C |
6: 43,251,691 (GRCm39) |
I814T |
probably benign |
Het |
| Atr |
A |
T |
9: 95,757,743 (GRCm39) |
R968* |
probably null |
Het |
| Bltp1 |
T |
A |
3: 37,028,321 (GRCm39) |
N2329K |
possibly damaging |
Het |
| Bltp1 |
C |
T |
3: 37,080,303 (GRCm39) |
S267L |
probably benign |
Het |
| Capn7 |
C |
T |
14: 31,074,401 (GRCm39) |
T268I |
probably benign |
Het |
| Ccn1 |
C |
T |
3: 145,354,447 (GRCm39) |
G155R |
probably damaging |
Het |
| Cubn |
A |
T |
2: 13,352,989 (GRCm39) |
F1916L |
probably benign |
Het |
| Cubn |
A |
G |
2: 13,494,728 (GRCm39) |
V107A |
possibly damaging |
Het |
| Cyp11b1 |
T |
A |
15: 74,707,691 (GRCm39) |
T473S |
probably damaging |
Het |
| Dyrk1b |
T |
C |
7: 27,883,737 (GRCm39) |
Y198H |
probably damaging |
Het |
| Echdc2 |
G |
T |
4: 108,031,274 (GRCm39) |
R206L |
probably benign |
Het |
| Ep400 |
C |
T |
5: 110,843,898 (GRCm39) |
R1594Q |
unknown |
Het |
| Fmnl2 |
G |
A |
2: 52,926,520 (GRCm39) |
R69Q |
|
Het |
| Fry |
T |
A |
5: 150,328,792 (GRCm39) |
H1308Q |
probably damaging |
Het |
| Fyb2 |
T |
A |
4: 104,867,651 (GRCm39) |
D667E |
probably benign |
Het |
| Gimap7 |
T |
A |
6: 48,700,791 (GRCm39) |
Y126N |
possibly damaging |
Het |
| Gm1979 |
A |
T |
5: 26,205,178 (GRCm39) |
W266R |
probably damaging |
Het |
| Gm28042 |
T |
A |
2: 119,870,197 (GRCm39) |
M712K |
possibly damaging |
Het |
| Gm3238 |
A |
G |
10: 77,606,469 (GRCm39) |
*231R |
probably null |
Het |
| Gm5592 |
C |
A |
7: 40,935,831 (GRCm39) |
A111E |
probably damaging |
Het |
| Gm7694 |
A |
G |
1: 170,128,717 (GRCm39) |
*271Q |
probably null |
Het |
| Ift81 |
T |
C |
5: 122,732,623 (GRCm39) |
M304V |
possibly damaging |
Het |
| Igfals |
T |
C |
17: 25,099,548 (GRCm39) |
L213P |
probably damaging |
Het |
| Ints3 |
G |
A |
3: 90,329,111 (GRCm39) |
P83S |
probably benign |
Het |
| Kcna10 |
T |
G |
3: 107,102,856 (GRCm39) |
S496A |
probably damaging |
Het |
| Kmt2d |
G |
A |
15: 98,741,600 (GRCm39) |
A4520V |
unknown |
Het |
| Lemd3 |
A |
T |
10: 120,813,995 (GRCm39) |
Y413N |
probably damaging |
Het |
| Lgr6 |
T |
C |
1: 134,923,770 (GRCm39) |
N453S |
probably damaging |
Het |
| Lmtk3 |
A |
C |
7: 45,441,998 (GRCm39) |
D352A |
probably damaging |
Het |
| Lrrc4c |
T |
C |
2: 97,461,024 (GRCm39) |
M550T |
possibly damaging |
Het |
| Maml2 |
A |
T |
9: 13,532,385 (GRCm39) |
Q533L |
|
Het |
| Mdn1 |
T |
A |
4: 32,741,344 (GRCm39) |
D3815E |
probably damaging |
Het |
| Megf8 |
C |
T |
7: 25,029,353 (GRCm39) |
A299V |
possibly damaging |
Het |
| Meis3 |
G |
T |
7: 15,911,481 (GRCm39) |
E59D |
probably benign |
Het |
| Mppe1 |
A |
G |
18: 67,358,775 (GRCm39) |
*398R |
probably null |
Het |
| Mtmr7 |
G |
A |
8: 41,059,927 (GRCm39) |
A62V |
possibly damaging |
Het |
| Mtus1 |
T |
A |
8: 41,537,006 (GRCm39) |
T237S |
possibly damaging |
Het |
| Ndfip2 |
T |
A |
14: 105,525,193 (GRCm39) |
V158E |
possibly damaging |
Het |
| Nrbp2 |
T |
G |
15: 75,962,746 (GRCm39) |
T53P |
probably damaging |
Het |
| Nrde2 |
G |
A |
12: 100,097,094 (GRCm39) |
P902L |
probably benign |
Het |
| Or10ab5 |
T |
A |
7: 108,244,879 (GRCm39) |
K301N |
probably damaging |
Het |
| Or11g24 |
T |
A |
14: 50,662,792 (GRCm39) |
M272K |
probably benign |
Het |
| Or2y13 |
A |
G |
11: 49,415,381 (GRCm39) |
Y277C |
probably damaging |
Het |
| Or51a10 |
T |
A |
7: 103,699,800 (GRCm39) |
|
probably benign |
Het |
| Or6c202 |
T |
C |
10: 128,995,924 (GRCm39) |
M310V |
probably benign |
Het |
| Pcdha1 |
A |
G |
18: 37,064,115 (GRCm39) |
T260A |
probably damaging |
Het |
| Pdlim1 |
T |
G |
19: 40,238,102 (GRCm39) |
K98N |
probably damaging |
Het |
| Phrf1 |
G |
A |
7: 140,834,842 (GRCm39) |
G207R |
unknown |
Het |
| Pik3r6 |
A |
G |
11: 68,419,389 (GRCm39) |
K124R |
probably damaging |
Het |
| Polr2b |
T |
A |
5: 77,488,268 (GRCm39) |
F823I |
probably benign |
Het |
| Prss58 |
T |
C |
6: 40,872,322 (GRCm39) |
I234V |
probably damaging |
Het |
| Ptpn14 |
A |
T |
1: 189,597,608 (GRCm39) |
N766I |
probably benign |
Het |
| Qrfprl |
T |
A |
6: 65,429,940 (GRCm39) |
I212N |
probably benign |
Het |
| Repin1 |
T |
A |
6: 48,574,756 (GRCm39) |
S562T |
probably damaging |
Het |
| Rgr |
C |
T |
14: 36,766,552 (GRCm39) |
D165N |
probably damaging |
Het |
| Rho |
T |
C |
6: 115,912,200 (GRCm39) |
F221L |
probably damaging |
Het |
| Rictor |
C |
T |
15: 6,801,635 (GRCm39) |
S441L |
probably benign |
Het |
| Rnase2a |
A |
G |
14: 51,493,248 (GRCm39) |
I39T |
probably damaging |
Het |
| Rpl13a |
T |
G |
7: 44,776,660 (GRCm39) |
I43L |
probably benign |
Het |
| Rpp30 |
T |
C |
19: 36,066,558 (GRCm39) |
V97A |
probably benign |
Het |
| Scube3 |
T |
C |
17: 28,386,023 (GRCm39) |
Y755H |
probably damaging |
Het |
| Sec24a |
A |
T |
11: 51,603,084 (GRCm39) |
V788E |
probably damaging |
Het |
| Spns2 |
A |
T |
11: 72,380,443 (GRCm39) |
L60* |
probably null |
Het |
| Strc |
T |
C |
2: 121,202,229 (GRCm39) |
N1213S |
possibly damaging |
Het |
| Tec |
A |
T |
5: 72,943,367 (GRCm39) |
I116N |
possibly damaging |
Het |
| Tll1 |
A |
T |
8: 64,546,988 (GRCm39) |
D319E |
probably benign |
Het |
| Tmem121b |
T |
C |
6: 120,470,388 (GRCm39) |
T110A |
unknown |
Het |
| Tmem232 |
T |
A |
17: 65,572,213 (GRCm39) |
I593F |
probably damaging |
Het |
| Tpp2 |
A |
G |
1: 44,009,626 (GRCm39) |
I487V |
probably benign |
Het |
| Ubr4 |
C |
A |
4: 139,136,178 (GRCm39) |
C934* |
probably null |
Het |
| Vmn1r68 |
A |
G |
7: 10,261,559 (GRCm39) |
Y180H |
probably benign |
Het |
| Vmn2r25 |
T |
C |
6: 123,816,882 (GRCm39) |
D233G |
possibly damaging |
Het |
| Wdr6 |
A |
G |
9: 108,453,560 (GRCm39) |
W108R |
possibly damaging |
Het |
| Zng1 |
A |
G |
19: 24,920,045 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Dip2c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00392:Dip2c
|
APN |
13 |
9,543,144 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL00426:Dip2c
|
APN |
13 |
9,656,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00503:Dip2c
|
APN |
13 |
9,617,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00586:Dip2c
|
APN |
13 |
9,660,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01306:Dip2c
|
APN |
13 |
9,625,179 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL01580:Dip2c
|
APN |
13 |
9,687,124 (GRCm39) |
splice site |
probably null |
|
|
IGL01985:Dip2c
|
APN |
13 |
9,603,303 (GRCm39) |
splice site |
probably benign |
|
|
IGL02060:Dip2c
|
APN |
13 |
9,672,666 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02122:Dip2c
|
APN |
13 |
9,556,695 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL02170:Dip2c
|
APN |
13 |
9,656,371 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02211:Dip2c
|
APN |
13 |
9,660,883 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02755:Dip2c
|
APN |
13 |
9,600,356 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02836:Dip2c
|
APN |
13 |
9,660,826 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02935:Dip2c
|
APN |
13 |
9,712,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03032:Dip2c
|
APN |
13 |
9,601,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ANU23:Dip2c
|
UTSW |
13 |
9,625,179 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
P0038:Dip2c
|
UTSW |
13 |
9,697,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0009:Dip2c
|
UTSW |
13 |
9,671,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0268:Dip2c
|
UTSW |
13 |
9,687,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0271:Dip2c
|
UTSW |
13 |
9,665,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0306:Dip2c
|
UTSW |
13 |
9,654,635 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0415:Dip2c
|
UTSW |
13 |
9,618,325 (GRCm39) |
splice site |
probably benign |
|
|
R0519:Dip2c
|
UTSW |
13 |
9,613,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0557:Dip2c
|
UTSW |
13 |
9,603,495 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0964:Dip2c
|
UTSW |
13 |
9,618,699 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0973:Dip2c
|
UTSW |
13 |
9,626,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0973:Dip2c
|
UTSW |
13 |
9,626,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0974:Dip2c
|
UTSW |
13 |
9,626,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1101:Dip2c
|
UTSW |
13 |
9,684,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1171:Dip2c
|
UTSW |
13 |
9,543,162 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1403:Dip2c
|
UTSW |
13 |
9,603,300 (GRCm39) |
splice site |
probably null |
|
|
R1403:Dip2c
|
UTSW |
13 |
9,603,300 (GRCm39) |
splice site |
probably null |
|
|
R1432:Dip2c
|
UTSW |
13 |
9,603,340 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1481:Dip2c
|
UTSW |
13 |
9,601,902 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1588:Dip2c
|
UTSW |
13 |
9,715,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1721:Dip2c
|
UTSW |
13 |
9,709,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1726:Dip2c
|
UTSW |
13 |
9,625,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1867:Dip2c
|
UTSW |
13 |
9,671,985 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R1909:Dip2c
|
UTSW |
13 |
9,583,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2013:Dip2c
|
UTSW |
13 |
9,617,882 (GRCm39) |
nonsense |
probably null |
|
|
R2022:Dip2c
|
UTSW |
13 |
9,601,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2517:Dip2c
|
UTSW |
13 |
9,659,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3746:Dip2c
|
UTSW |
13 |
9,651,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3794:Dip2c
|
UTSW |
13 |
9,654,597 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3884:Dip2c
|
UTSW |
13 |
9,601,894 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4019:Dip2c
|
UTSW |
13 |
9,664,401 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4110:Dip2c
|
UTSW |
13 |
9,687,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4111:Dip2c
|
UTSW |
13 |
9,687,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4113:Dip2c
|
UTSW |
13 |
9,687,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4256:Dip2c
|
UTSW |
13 |
9,659,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4300:Dip2c
|
UTSW |
13 |
9,660,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4494:Dip2c
|
UTSW |
13 |
9,621,098 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4739:Dip2c
|
UTSW |
13 |
9,583,375 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4812:Dip2c
|
UTSW |
13 |
9,687,166 (GRCm39) |
nonsense |
probably null |
|
|
R4814:Dip2c
|
UTSW |
13 |
9,586,896 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4816:Dip2c
|
UTSW |
13 |
9,625,186 (GRCm39) |
missense |
probably benign |
0.37 |
|
R4828:Dip2c
|
UTSW |
13 |
9,610,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4915:Dip2c
|
UTSW |
13 |
9,671,905 (GRCm39) |
splice site |
probably null |
|
|
R4917:Dip2c
|
UTSW |
13 |
9,671,905 (GRCm39) |
splice site |
probably null |
|
|
R4932:Dip2c
|
UTSW |
13 |
9,674,008 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4993:Dip2c
|
UTSW |
13 |
9,625,259 (GRCm39) |
nonsense |
probably null |
|
|
R5043:Dip2c
|
UTSW |
13 |
9,601,863 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5349:Dip2c
|
UTSW |
13 |
9,672,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5744:Dip2c
|
UTSW |
13 |
9,618,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5840:Dip2c
|
UTSW |
13 |
9,556,712 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6110:Dip2c
|
UTSW |
13 |
9,673,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6160:Dip2c
|
UTSW |
13 |
9,583,290 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6161:Dip2c
|
UTSW |
13 |
9,697,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6477:Dip2c
|
UTSW |
13 |
9,673,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6522:Dip2c
|
UTSW |
13 |
9,625,264 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6603:Dip2c
|
UTSW |
13 |
9,704,624 (GRCm39) |
splice site |
probably null |
|
|
R6658:Dip2c
|
UTSW |
13 |
9,543,213 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6672:Dip2c
|
UTSW |
13 |
9,617,866 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6697:Dip2c
|
UTSW |
13 |
9,671,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6991:Dip2c
|
UTSW |
13 |
9,684,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6991:Dip2c
|
UTSW |
13 |
9,601,896 (GRCm39) |
nonsense |
probably null |
|
|
R7018:Dip2c
|
UTSW |
13 |
9,709,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7053:Dip2c
|
UTSW |
13 |
9,660,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7102:Dip2c
|
UTSW |
13 |
9,654,572 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7171:Dip2c
|
UTSW |
13 |
9,556,684 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7371:Dip2c
|
UTSW |
13 |
9,642,785 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7395:Dip2c
|
UTSW |
13 |
9,664,413 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7489:Dip2c
|
UTSW |
13 |
9,583,348 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7575:Dip2c
|
UTSW |
13 |
9,678,048 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7642:Dip2c
|
UTSW |
13 |
9,672,741 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7687:Dip2c
|
UTSW |
13 |
9,654,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7700:Dip2c
|
UTSW |
13 |
9,709,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7715:Dip2c
|
UTSW |
13 |
9,664,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7842:Dip2c
|
UTSW |
13 |
9,656,569 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7845:Dip2c
|
UTSW |
13 |
9,659,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8354:Dip2c
|
UTSW |
13 |
9,671,918 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8685:Dip2c
|
UTSW |
13 |
9,687,161 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8779:Dip2c
|
UTSW |
13 |
9,660,845 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8786:Dip2c
|
UTSW |
13 |
9,665,830 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8815:Dip2c
|
UTSW |
13 |
9,673,834 (GRCm39) |
nonsense |
probably null |
|
|
R8833:Dip2c
|
UTSW |
13 |
9,625,519 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8868:Dip2c
|
UTSW |
13 |
9,625,503 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8873:Dip2c
|
UTSW |
13 |
9,625,182 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8887:Dip2c
|
UTSW |
13 |
9,673,989 (GRCm39) |
splice site |
probably benign |
|
|
R8923:Dip2c
|
UTSW |
13 |
9,673,901 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9112:Dip2c
|
UTSW |
13 |
9,660,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9424:Dip2c
|
UTSW |
13 |
9,709,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9474:Dip2c
|
UTSW |
13 |
9,544,963 (GRCm39) |
missense |
unknown |
|
|
R9527:Dip2c
|
UTSW |
13 |
9,544,875 (GRCm39) |
missense |
unknown |
|
|
R9593:Dip2c
|
UTSW |
13 |
9,704,683 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9615:Dip2c
|
UTSW |
13 |
9,625,191 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9801:Dip2c
|
UTSW |
13 |
9,626,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATTGTGGAAAACAGGTTGCTG -3'
(R):5'- TTTCAGATGAGTAAGGGCAAGC -3'
Sequencing Primer
(F):5'- TGGAAAACAGGTTGCTGTGTAG -3'
(R):5'- TGGTGTGGCTCTCAACCTCAAAG -3'
|
| Posted On |
2019-11-12 |
Incidental Mutation