Incidental Mutation 'R8116:Shprh'
| ID |
631213 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Shprh
|
| Ensembl Gene |
ENSMUSG00000090112 |
| Gene Name |
SNF2 histone linker PHD RING helicase |
| Synonyms |
2610103K11Rik, D230017O13Rik |
| MMRRC Submission |
067545-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8116 (G1)
|
| Quality Score |
191.009 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
11025171-11093339 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 11089205 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 1648
(S1648P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000039422
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000044053]
[ENSMUST00000054814]
[ENSMUST00000159541]
|
| AlphaFold |
Q7TPQ3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000044053
AA Change: S1648P
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000039422
Gene: ENSMUSG00000090112
AA Change: S1648P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
Pfam:Helicase_C
|
1500 |
1613 |
1.6e-8 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000054814
|
| SMART Domains |
Protein: ENSMUSP00000125849
Gene: ENSMUSG00000090112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
SCOP:d1fuka_
|
1504 |
1616 |
6e-8 |
SMART |
|
Blast:HELICc
|
1533 |
1613 |
4e-46 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159541
|
| SMART Domains |
Protein: ENSMUSP00000132870
Gene: ENSMUSG00000090112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
SCOP:d1fuka_
|
1504 |
1619 |
4e-8 |
SMART |
|
Blast:HELICc
|
1533 |
1613 |
6e-46 |
BLAST |
|
| Coding Region Coverage |
- 1x: 99.8%
- 3x: 99.6%
- 10x: 98.5%
- 20x: 93.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006 [PubMed 17108083]).[supplied by OMIM, Mar 2008]
PHENOTYPE: The gene product is an E3 ligase involved in poly-ubiquitination of Pcna. Neither homozygous truncation nor KO affect B cell somatic hypermutation or class switching. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 69 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca8a |
A |
T |
11: 109,982,420 (GRCm39) |
N7K |
probably benign |
Het |
| Akap9 |
T |
A |
5: 4,111,183 (GRCm39) |
D3081E |
probably benign |
Het |
| Amer2 |
G |
A |
14: 60,616,854 (GRCm39) |
A350T |
probably damaging |
Het |
| Amotl1 |
A |
G |
9: 14,466,868 (GRCm39) |
|
probably null |
Het |
| Ankib1 |
A |
T |
5: 3,752,995 (GRCm39) |
V651E |
probably damaging |
Het |
| Aox1 |
T |
C |
1: 58,115,283 (GRCm39) |
V756A |
probably damaging |
Het |
| Arap2 |
A |
C |
5: 62,887,954 (GRCm39) |
I464S |
probably benign |
Het |
| Atp8a2 |
A |
C |
14: 60,263,657 (GRCm39) |
M359R |
probably damaging |
Het |
| Aunip |
T |
C |
4: 134,250,618 (GRCm39) |
S188P |
possibly damaging |
Het |
| Cdt1 |
A |
G |
8: 123,298,728 (GRCm39) |
E455G |
probably benign |
Het |
| Cyp2r1 |
G |
T |
7: 114,149,590 (GRCm39) |
H475N |
probably benign |
Het |
| Dnah7a |
G |
T |
1: 53,543,049 (GRCm39) |
H2374N |
probably benign |
Het |
| Dsc2 |
C |
T |
18: 20,165,331 (GRCm39) |
G881R |
possibly damaging |
Het |
| Dst |
G |
A |
1: 34,313,261 (GRCm39) |
A4343T |
probably benign |
Het |
| Efcab3 |
A |
G |
11: 105,002,677 (GRCm39) |
D304G |
possibly damaging |
Het |
| Efcc1 |
T |
C |
6: 87,728,772 (GRCm39) |
L409P |
probably damaging |
Het |
| Eno1 |
G |
T |
4: 150,325,526 (GRCm39) |
S37I |
probably damaging |
Het |
| Ermp1 |
A |
T |
19: 29,601,196 (GRCm39) |
L517Q |
probably damaging |
Het |
| Farp1 |
T |
G |
14: 121,471,232 (GRCm39) |
I196S |
probably damaging |
Het |
| Fbxo21 |
A |
G |
5: 118,128,919 (GRCm39) |
T310A |
possibly damaging |
Het |
| Fbxo31 |
C |
T |
8: 122,287,127 (GRCm39) |
V149M |
probably damaging |
Het |
| Ggcx |
C |
A |
6: 72,406,511 (GRCm39) |
T658N |
possibly damaging |
Het |
| Gpc5 |
A |
C |
14: 115,636,637 (GRCm39) |
H440P |
probably damaging |
Het |
| H13 |
C |
T |
2: 152,537,446 (GRCm39) |
A297V |
probably damaging |
Het |
| H2-DMb1 |
T |
A |
17: 34,374,443 (GRCm39) |
L31Q |
probably damaging |
Het |
| Ifi207 |
G |
A |
1: 173,557,746 (GRCm39) |
P331S |
unknown |
Het |
| Il11ra1 |
G |
T |
4: 41,766,251 (GRCm39) |
A263S |
probably benign |
Het |
| Il1a |
C |
A |
2: 129,144,864 (GRCm39) |
V185F |
probably damaging |
Het |
| Ippk |
C |
T |
13: 49,599,818 (GRCm39) |
P226S |
|
Het |
| Kdm4d |
T |
A |
9: 14,375,237 (GRCm39) |
K207M |
probably damaging |
Het |
| Lrrc37 |
A |
T |
11: 103,434,115 (GRCm39) |
M3018K |
unknown |
Het |
| Lrrc4b |
T |
C |
7: 44,110,533 (GRCm39) |
L135P |
probably damaging |
Het |
| Lrrk1 |
A |
G |
7: 65,912,371 (GRCm39) |
Y1730H |
possibly damaging |
Het |
| Mcpt2 |
C |
A |
14: 56,279,663 (GRCm39) |
A18D |
probably damaging |
Het |
| Mtmr4 |
C |
T |
11: 87,502,756 (GRCm39) |
R937* |
probably null |
Het |
| Muc16 |
T |
A |
9: 18,570,033 (GRCm39) |
T829S |
unknown |
Het |
| Myof |
A |
C |
19: 37,921,167 (GRCm39) |
I1365S |
probably damaging |
Het |
| Npc2 |
C |
T |
12: 84,807,612 (GRCm39) |
R82Q |
probably benign |
Het |
| Or10ag2 |
T |
A |
2: 87,249,081 (GRCm39) |
S228T |
probably damaging |
Het |
| Or10d1c |
A |
T |
9: 38,894,169 (GRCm39) |
M57K |
probably damaging |
Het |
| Or10j2 |
T |
A |
1: 173,098,047 (GRCm39) |
F102I |
possibly damaging |
Het |
| Or2g25 |
G |
A |
17: 37,970,631 (GRCm39) |
L198F |
probably damaging |
Het |
| Or4k45 |
T |
C |
2: 111,395,783 (GRCm39) |
D2G |
probably benign |
Het |
| Or8b3b |
A |
T |
9: 38,584,464 (GRCm39) |
I92N |
possibly damaging |
Het |
| Or8d2b |
T |
A |
9: 38,789,026 (GRCm39) |
S185T |
probably damaging |
Het |
| Pdzph1 |
T |
C |
17: 59,282,138 (GRCm39) |
N48S |
probably benign |
Het |
| Plce1 |
A |
T |
19: 38,513,262 (GRCm39) |
H187L |
probably benign |
Het |
| Pramel6 |
G |
T |
2: 87,338,808 (GRCm39) |
V3F |
probably benign |
Het |
| Prr5l |
CCTCGCTCGCTCGCTCGC |
CCTCGCTCGCTCGC |
2: 101,627,919 (GRCm39) |
|
probably null |
Het |
| Pwwp3a |
G |
A |
10: 80,076,231 (GRCm39) |
G474S |
probably damaging |
Het |
| Rabgap1l |
A |
G |
1: 160,530,012 (GRCm39) |
Y358H |
probably benign |
Het |
| Rbbp8 |
T |
C |
18: 11,855,727 (GRCm39) |
S625P |
probably damaging |
Het |
| Rhot1 |
A |
T |
11: 80,141,879 (GRCm39) |
K461I |
probably benign |
Het |
| Rpa1 |
G |
A |
11: 75,193,501 (GRCm39) |
T610I |
possibly damaging |
Het |
| Ryr1 |
G |
T |
7: 28,810,308 (GRCm39) |
H316N |
probably benign |
Het |
| Sipa1 |
A |
T |
19: 5,702,140 (GRCm39) |
D923E |
possibly damaging |
Het |
| Spata6 |
A |
G |
4: 111,685,517 (GRCm39) |
Y474C |
possibly damaging |
Het |
| Sptbn1 |
A |
T |
11: 30,089,117 (GRCm39) |
I715N |
probably damaging |
Het |
| Stab1 |
A |
T |
14: 30,880,910 (GRCm39) |
D627E |
possibly damaging |
Het |
| Stard9 |
T |
A |
2: 120,495,420 (GRCm39) |
C98* |
probably null |
Het |
| Tfpi2 |
T |
C |
6: 3,963,872 (GRCm39) |
T187A |
probably damaging |
Het |
| Tmem63a |
G |
T |
1: 180,788,048 (GRCm39) |
K267N |
probably benign |
Het |
| Topaz1 |
C |
T |
9: 122,604,708 (GRCm39) |
A1104V |
probably benign |
Het |
| Trmt11 |
A |
G |
10: 30,442,490 (GRCm39) |
I231T |
possibly damaging |
Het |
| Utp15 |
G |
A |
13: 98,387,371 (GRCm39) |
T401I |
probably benign |
Het |
| Vmn2r13 |
T |
C |
5: 109,322,926 (GRCm39) |
K121R |
probably benign |
Het |
| Xab2 |
C |
T |
8: 3,663,830 (GRCm39) |
R363H |
probably damaging |
Het |
| Zfand2b |
T |
A |
1: 75,145,504 (GRCm39) |
F3L |
possibly damaging |
Het |
| Zfyve28 |
A |
T |
5: 34,374,944 (GRCm39) |
S357T |
probably damaging |
Het |
|
| Other mutations in Shprh |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00492:Shprh
|
APN |
10 |
11,063,902 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00583:Shprh
|
APN |
10 |
11,063,764 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL00684:Shprh
|
APN |
10 |
11,038,781 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL01295:Shprh
|
APN |
10 |
11,059,612 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01387:Shprh
|
APN |
10 |
11,045,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01635:Shprh
|
APN |
10 |
11,045,763 (GRCm39) |
nonsense |
probably null |
|
|
IGL01833:Shprh
|
APN |
10 |
11,066,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02013:Shprh
|
APN |
10 |
11,057,246 (GRCm39) |
splice site |
probably benign |
|
|
IGL02502:Shprh
|
APN |
10 |
11,070,101 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL02819:Shprh
|
APN |
10 |
11,030,509 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
PIT4581001:Shprh
|
UTSW |
10 |
11,068,238 (GRCm39) |
frame shift |
probably null |
|
|
R0010:Shprh
|
UTSW |
10 |
11,027,675 (GRCm39) |
missense |
probably benign |
|
|
R0010:Shprh
|
UTSW |
10 |
11,027,675 (GRCm39) |
missense |
probably benign |
|
|
R0053:Shprh
|
UTSW |
10 |
11,070,116 (GRCm39) |
splice site |
probably null |
|
|
R0053:Shprh
|
UTSW |
10 |
11,070,116 (GRCm39) |
splice site |
probably null |
|
|
R0255:Shprh
|
UTSW |
10 |
11,062,135 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0325:Shprh
|
UTSW |
10 |
11,045,853 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0331:Shprh
|
UTSW |
10 |
11,069,914 (GRCm39) |
splice site |
probably benign |
|
|
R0494:Shprh
|
UTSW |
10 |
11,032,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0532:Shprh
|
UTSW |
10 |
11,038,556 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0546:Shprh
|
UTSW |
10 |
11,059,631 (GRCm39) |
splice site |
probably benign |
|
|
R0574:Shprh
|
UTSW |
10 |
11,038,821 (GRCm39) |
unclassified |
probably benign |
|
|
R0605:Shprh
|
UTSW |
10 |
11,082,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0662:Shprh
|
UTSW |
10 |
11,062,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1148:Shprh
|
UTSW |
10 |
11,089,226 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1148:Shprh
|
UTSW |
10 |
11,089,226 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1263:Shprh
|
UTSW |
10 |
11,035,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1588:Shprh
|
UTSW |
10 |
11,040,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1638:Shprh
|
UTSW |
10 |
11,032,822 (GRCm39) |
missense |
probably benign |
|
|
R1830:Shprh
|
UTSW |
10 |
11,062,655 (GRCm39) |
splice site |
probably null |
|
|
R1898:Shprh
|
UTSW |
10 |
11,062,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1903:Shprh
|
UTSW |
10 |
11,059,541 (GRCm39) |
nonsense |
probably null |
|
|
R2060:Shprh
|
UTSW |
10 |
11,027,864 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2225:Shprh
|
UTSW |
10 |
11,037,979 (GRCm39) |
unclassified |
probably benign |
|
|
R2363:Shprh
|
UTSW |
10 |
11,047,697 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2509:Shprh
|
UTSW |
10 |
11,042,468 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2891:Shprh
|
UTSW |
10 |
11,040,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3077:Shprh
|
UTSW |
10 |
11,046,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3150:Shprh
|
UTSW |
10 |
11,045,774 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3796:Shprh
|
UTSW |
10 |
11,054,501 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4196:Shprh
|
UTSW |
10 |
11,083,604 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4423:Shprh
|
UTSW |
10 |
11,062,262 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4488:Shprh
|
UTSW |
10 |
11,036,215 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4748:Shprh
|
UTSW |
10 |
11,046,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4768:Shprh
|
UTSW |
10 |
11,057,284 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4867:Shprh
|
UTSW |
10 |
11,040,301 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4937:Shprh
|
UTSW |
10 |
11,032,863 (GRCm39) |
missense |
probably benign |
|
|
R5140:Shprh
|
UTSW |
10 |
11,030,449 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5318:Shprh
|
UTSW |
10 |
11,042,301 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5323:Shprh
|
UTSW |
10 |
11,046,041 (GRCm39) |
splice site |
probably null |
|
|
R5450:Shprh
|
UTSW |
10 |
11,088,074 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R5872:Shprh
|
UTSW |
10 |
11,063,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6030:Shprh
|
UTSW |
10 |
11,027,735 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6030:Shprh
|
UTSW |
10 |
11,027,735 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6392:Shprh
|
UTSW |
10 |
11,054,485 (GRCm39) |
nonsense |
probably null |
|
|
R6416:Shprh
|
UTSW |
10 |
11,043,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6470:Shprh
|
UTSW |
10 |
11,047,681 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6513:Shprh
|
UTSW |
10 |
11,062,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6530:Shprh
|
UTSW |
10 |
11,070,011 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6678:Shprh
|
UTSW |
10 |
11,042,289 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6757:Shprh
|
UTSW |
10 |
11,057,252 (GRCm39) |
splice site |
probably null |
|
|
R6971:Shprh
|
UTSW |
10 |
11,042,437 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7158:Shprh
|
UTSW |
10 |
11,042,474 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7582:Shprh
|
UTSW |
10 |
11,040,449 (GRCm39) |
missense |
probably benign |
|
|
R7757:Shprh
|
UTSW |
10 |
11,037,924 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7812:Shprh
|
UTSW |
10 |
11,027,735 (GRCm39) |
missense |
probably benign |
|
|
R7998:Shprh
|
UTSW |
10 |
11,061,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8061:Shprh
|
UTSW |
10 |
11,088,077 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8082:Shprh
|
UTSW |
10 |
11,027,555 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8390:Shprh
|
UTSW |
10 |
11,063,727 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8445:Shprh
|
UTSW |
10 |
11,057,313 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8530:Shprh
|
UTSW |
10 |
11,027,678 (GRCm39) |
missense |
probably benign |
0.37 |
|
R8759:Shprh
|
UTSW |
10 |
11,032,908 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8937:Shprh
|
UTSW |
10 |
11,061,181 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R8995:Shprh
|
UTSW |
10 |
11,040,574 (GRCm39) |
nonsense |
probably null |
|
|
R9053:Shprh
|
UTSW |
10 |
11,030,446 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9131:Shprh
|
UTSW |
10 |
11,038,589 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R9176:Shprh
|
UTSW |
10 |
11,036,320 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9391:Shprh
|
UTSW |
10 |
11,038,633 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9423:Shprh
|
UTSW |
10 |
11,081,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9563:Shprh
|
UTSW |
10 |
11,042,235 (GRCm39) |
nonsense |
probably null |
|
|
R9668:Shprh
|
UTSW |
10 |
11,082,076 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9709:Shprh
|
UTSW |
10 |
11,038,574 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9718:Shprh
|
UTSW |
10 |
11,089,248 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9750:Shprh
|
UTSW |
10 |
11,040,204 (GRCm39) |
missense |
probably damaging |
0.98 |
|
RF012:Shprh
|
UTSW |
10 |
11,040,585 (GRCm39) |
missense |
probably benign |
0.02 |
|
V8831:Shprh
|
UTSW |
10 |
11,062,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Shprh
|
UTSW |
10 |
11,062,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Shprh
|
UTSW |
10 |
11,040,297 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Shprh
|
UTSW |
10 |
11,027,506 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGAACCTGCTTGACAACAGTTG -3'
(R):5'- GGAACCAATTGCCAATTATTACTAGGC -3'
Sequencing Primer
(F):5'- AGCATTTTCTGACAAAGCTTCAG -3'
(R):5'- AATTGCCAATTATTACTAGGCTAGAG -3'
|
| Posted On |
2020-06-30 |
Incidental Mutation