Incidental Mutation 'R1503:Sned1'
| ID |
169412 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sned1
|
| Ensembl Gene |
ENSMUSG00000047793 |
| Gene Name |
sushi, nidogen and EGF-like domains 1 |
| Synonyms |
D430044C15Rik, 6720455I24Rik, Snep |
| MMRRC Submission |
039553-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.076)
|
| Stock # |
R1503 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
93163563-93228787 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 93209376 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Methionine
at position 830
(V830M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000050832
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000062202]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000062202
AA Change: V830M
PolyPhen 2
Score 0.895 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000050832
Gene: ENSMUSG00000047793
AA Change: V830M
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
24 |
N/A |
INTRINSIC |
|
NIDO
|
103 |
260 |
2.98e-54 |
SMART |
|
EGF
|
271 |
309 |
3.79e-6 |
SMART |
|
EGF_CA
|
311 |
347 |
2.42e-13 |
SMART |
|
EGF
|
352 |
385 |
1.02e-6 |
SMART |
|
EGF_CA
|
387 |
423 |
1.91e-11 |
SMART |
|
EGF
|
432 |
465 |
2.96e-8 |
SMART |
|
EGF
|
471 |
500 |
6.02e0 |
SMART |
|
EGF
|
544 |
577 |
3.54e-6 |
SMART |
|
EGF
|
583 |
616 |
6.06e-5 |
SMART |
|
EGF_CA
|
619 |
655 |
2.33e-6 |
SMART |
|
EGF
|
660 |
693 |
1.77e-6 |
SMART |
|
CCP
|
698 |
751 |
2.5e-11 |
SMART |
|
EGF_CA
|
753 |
789 |
1.66e-11 |
SMART |
|
EGF_CA
|
791 |
827 |
1.38e-8 |
SMART |
|
EGF_CA
|
829 |
865 |
1.92e-7 |
SMART |
|
EGF
|
870 |
903 |
2.35e-2 |
SMART |
|
FN3
|
906 |
991 |
1.7e-4 |
SMART |
|
FN3
|
1005 |
1084 |
1.38e-4 |
SMART |
|
FN3
|
1104 |
1185 |
1.6e-9 |
SMART |
|
EGF
|
1309 |
1342 |
6.16e-6 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000163688
AA Change: V39M
|
| SMART Domains |
Protein: ENSMUSP00000132455
Gene: ENSMUSG00000047793
AA Change: V39M
| Domain | Start | End | E-Value | Type |
|---|
|
EGF_CA
|
1 |
37 |
6.7e-7 |
SMART |
|
EGF_CA
|
39 |
75 |
1.92e-7 |
SMART |
|
EGF
|
80 |
113 |
2.35e-2 |
SMART |
|
FN3
|
116 |
201 |
1.7e-4 |
SMART |
|
FN3
|
215 |
294 |
1.38e-4 |
SMART |
|
FN3
|
314 |
395 |
1.6e-9 |
SMART |
|
EGF
|
487 |
520 |
6.16e-6 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000165843
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000172289
|
| Meta Mutation Damage Score |
0.1152 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.2%
- 10x: 96.1%
- 20x: 92.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Arhgef6 |
T |
C |
X: 56,383,922 (GRCm39) |
M5V |
probably benign |
Het |
| Atf7ip |
G |
T |
6: 136,583,865 (GRCm39) |
V1299L |
probably damaging |
Het |
| Atp12a |
A |
T |
14: 56,610,881 (GRCm39) |
N342Y |
probably damaging |
Het |
| Atp8b5 |
G |
A |
4: 43,344,430 (GRCm39) |
G439D |
probably damaging |
Het |
| Bpifb2 |
G |
A |
2: 153,731,430 (GRCm39) |
D269N |
possibly damaging |
Het |
| Btd |
T |
G |
14: 31,389,612 (GRCm39) |
C444W |
probably damaging |
Het |
| Cacna1a |
A |
G |
8: 85,328,575 (GRCm39) |
D1624G |
probably benign |
Het |
| Carmil3 |
A |
C |
14: 55,735,737 (GRCm39) |
N563T |
probably damaging |
Het |
| Cars1 |
T |
C |
7: 143,122,726 (GRCm39) |
R538G |
probably benign |
Het |
| Catsperd |
A |
G |
17: 56,961,525 (GRCm39) |
K416E |
possibly damaging |
Het |
| Cc2d2a |
A |
T |
5: 43,852,581 (GRCm39) |
Y386F |
probably damaging |
Het |
| Ccpg1 |
A |
G |
9: 72,906,760 (GRCm39) |
N66S |
probably benign |
Het |
| Cd48 |
T |
A |
1: 171,523,415 (GRCm39) |
L86H |
probably damaging |
Het |
| Cdan1 |
A |
T |
2: 120,560,056 (GRCm39) |
H369Q |
probably damaging |
Het |
| Chil4 |
T |
C |
3: 106,113,350 (GRCm39) |
D189G |
probably benign |
Het |
| Cit |
T |
A |
5: 116,011,959 (GRCm39) |
Y189N |
possibly damaging |
Het |
| Cntn3 |
G |
A |
6: 102,441,526 (GRCm39) |
Q7* |
probably null |
Het |
| Csn1s2a |
A |
T |
5: 87,923,658 (GRCm39) |
I5F |
possibly damaging |
Het |
| Ctnnd1 |
C |
T |
2: 84,435,523 (GRCm39) |
|
probably null |
Het |
| Dmxl2 |
A |
T |
9: 54,354,272 (GRCm39) |
Y391* |
probably null |
Het |
| Dnah12 |
T |
C |
14: 26,495,649 (GRCm39) |
S1426P |
probably damaging |
Het |
| Dnhd1 |
T |
G |
7: 105,342,867 (GRCm39) |
S1404A |
possibly damaging |
Het |
| Drosha |
T |
A |
15: 12,848,159 (GRCm39) |
C484S |
probably benign |
Het |
| Dsg4 |
A |
T |
18: 20,582,736 (GRCm39) |
I125F |
probably damaging |
Het |
| Egfr |
T |
A |
11: 16,819,301 (GRCm39) |
M277K |
possibly damaging |
Het |
| Eml5 |
G |
T |
12: 98,797,433 (GRCm39) |
L1059I |
probably damaging |
Het |
| Erbb4 |
G |
T |
1: 68,385,705 (GRCm39) |
H295N |
probably benign |
Het |
| Etl4 |
T |
G |
2: 20,748,685 (GRCm39) |
V139G |
possibly damaging |
Het |
| Fhip1a |
T |
A |
3: 85,579,784 (GRCm39) |
Y807F |
possibly damaging |
Het |
| Frem3 |
A |
T |
8: 81,413,647 (GRCm39) |
E1969D |
probably damaging |
Het |
| Gdf3 |
T |
A |
6: 122,583,296 (GRCm39) |
D357V |
probably damaging |
Het |
| Gimap8 |
T |
A |
6: 48,624,463 (GRCm39) |
|
probably null |
Het |
| Gml2 |
C |
A |
15: 74,693,201 (GRCm39) |
S68* |
probably null |
Het |
| Gphn |
A |
G |
12: 78,551,403 (GRCm39) |
I248V |
possibly damaging |
Het |
| Greb1 |
A |
T |
12: 16,774,820 (GRCm39) |
Y192* |
probably null |
Het |
| Hmbs |
A |
C |
9: 44,248,729 (GRCm39) |
L215W |
probably benign |
Het |
| Iglon5 |
T |
A |
7: 43,128,449 (GRCm39) |
T123S |
probably benign |
Het |
| Ints2 |
C |
T |
11: 86,117,607 (GRCm39) |
R705H |
probably damaging |
Het |
| Ints8 |
A |
T |
4: 11,245,842 (GRCm39) |
L212Q |
probably damaging |
Het |
| Itgad |
A |
G |
7: 127,797,293 (GRCm39) |
Y846C |
probably benign |
Het |
| Kcnj1 |
A |
G |
9: 32,307,788 (GRCm39) |
T51A |
probably damaging |
Het |
| Kif9 |
A |
T |
9: 110,339,506 (GRCm39) |
K449N |
possibly damaging |
Het |
| Kifbp |
A |
G |
10: 62,395,187 (GRCm39) |
V485A |
probably damaging |
Het |
| Klk1b11 |
G |
A |
7: 43,428,333 (GRCm39) |
W241* |
probably null |
Het |
| Krt32 |
T |
C |
11: 99,974,936 (GRCm39) |
|
probably null |
Het |
| Loxl1 |
A |
G |
9: 58,200,923 (GRCm39) |
F513S |
probably damaging |
Het |
| Mapk8ip3 |
A |
T |
17: 25,123,897 (GRCm39) |
S571T |
probably damaging |
Het |
| Mcam |
C |
T |
9: 44,052,588 (GRCm39) |
R606C |
probably damaging |
Het |
| Mtss1 |
T |
C |
15: 58,823,521 (GRCm39) |
N282S |
probably damaging |
Het |
| Myh13 |
T |
A |
11: 67,244,500 (GRCm39) |
D1012E |
probably benign |
Het |
| Myo16 |
A |
G |
8: 10,552,817 (GRCm39) |
T952A |
probably benign |
Het |
| Neb |
T |
C |
2: 52,188,632 (GRCm39) |
D874G |
probably damaging |
Het |
| Nek11 |
A |
G |
9: 105,040,403 (GRCm39) |
Y553H |
probably damaging |
Het |
| Nr2c2 |
T |
A |
6: 92,082,312 (GRCm39) |
V9D |
probably benign |
Het |
| Nxf1 |
T |
A |
19: 8,739,800 (GRCm39) |
F51L |
probably benign |
Het |
| Or1e1f |
T |
G |
11: 73,855,394 (GRCm39) |
|
probably null |
Het |
| Or1j15 |
A |
T |
2: 36,458,885 (GRCm39) |
I92F |
probably damaging |
Het |
| Or2aj5 |
A |
G |
16: 19,425,062 (GRCm39) |
S119P |
probably benign |
Het |
| Or4c35 |
T |
C |
2: 89,808,872 (GRCm39) |
V250A |
probably damaging |
Het |
| Or5bw2 |
A |
G |
7: 6,573,470 (GRCm39) |
N160S |
probably damaging |
Het |
| Or6s1 |
A |
G |
14: 51,308,191 (GRCm39) |
S220P |
probably damaging |
Het |
| Or6z6 |
T |
C |
7: 6,491,178 (GRCm39) |
I232V |
probably damaging |
Het |
| Pcdhb8 |
A |
T |
18: 37,489,572 (GRCm39) |
N76Y |
probably damaging |
Het |
| Pdzrn4 |
T |
A |
15: 92,297,685 (GRCm39) |
F217I |
probably damaging |
Het |
| Ppp1r16a |
T |
A |
15: 76,578,599 (GRCm39) |
H434Q |
probably benign |
Het |
| Prpf19 |
T |
A |
19: 10,878,386 (GRCm39) |
F291I |
possibly damaging |
Het |
| R3hdm2 |
G |
T |
10: 127,307,695 (GRCm39) |
E319* |
probably null |
Het |
| Sel1l3 |
A |
G |
5: 53,295,271 (GRCm39) |
Y777H |
probably damaging |
Het |
| Serpinb5 |
G |
A |
1: 106,798,019 (GRCm39) |
A3T |
possibly damaging |
Het |
| Skp2 |
C |
A |
15: 9,127,998 (GRCm39) |
V88F |
probably damaging |
Het |
| Slc25a16 |
T |
C |
10: 62,764,155 (GRCm39) |
Y71H |
probably damaging |
Het |
| Slc6a6 |
T |
A |
6: 91,717,973 (GRCm39) |
I304N |
probably damaging |
Het |
| Sox17 |
C |
A |
1: 4,562,151 (GRCm39) |
G222C |
probably damaging |
Het |
| Trmu |
T |
A |
15: 85,779,220 (GRCm39) |
V289E |
possibly damaging |
Het |
| Vdac2 |
A |
G |
14: 21,887,945 (GRCm39) |
E96G |
probably damaging |
Het |
| Wdhd1 |
A |
T |
14: 47,484,857 (GRCm39) |
D885E |
probably benign |
Het |
| Zfp646 |
A |
G |
7: 127,479,308 (GRCm39) |
N495S |
probably damaging |
Het |
| Zfp663 |
T |
C |
2: 165,194,573 (GRCm39) |
T549A |
probably damaging |
Het |
| Zfp935 |
G |
A |
13: 62,602,951 (GRCm39) |
A83V |
possibly damaging |
Het |
|
| Other mutations in Sned1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00785:Sned1
|
APN |
1 |
93,201,891 (GRCm39) |
splice site |
probably benign |
|
|
IGL00955:Sned1
|
APN |
1 |
93,202,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01367:Sned1
|
APN |
1 |
93,210,936 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL02116:Sned1
|
APN |
1 |
93,209,447 (GRCm39) |
nonsense |
probably null |
|
|
IGL02195:Sned1
|
APN |
1 |
93,201,882 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02390:Sned1
|
APN |
1 |
93,189,386 (GRCm39) |
missense |
probably benign |
|
|
IGL02423:Sned1
|
APN |
1 |
93,211,322 (GRCm39) |
missense |
probably benign |
|
|
IGL02451:Sned1
|
APN |
1 |
93,163,930 (GRCm39) |
splice site |
probably benign |
|
|
IGL02567:Sned1
|
APN |
1 |
93,202,069 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03184:Sned1
|
APN |
1 |
93,202,390 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03328:Sned1
|
APN |
1 |
93,217,089 (GRCm39) |
missense |
probably benign |
|
|
Bulger
|
UTSW |
1 |
93,199,385 (GRCm39) |
nonsense |
probably null |
|
|
farina
|
UTSW |
1 |
93,209,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Millet
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
triticale
|
UTSW |
1 |
93,281,654 (GRCm39) |
missense |
|
|
|
R0257:Sned1
|
UTSW |
1 |
93,192,819 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R0372:Sned1
|
UTSW |
1 |
93,213,673 (GRCm39) |
splice site |
probably benign |
|
|
R0525:Sned1
|
UTSW |
1 |
93,199,696 (GRCm39) |
splice site |
probably null |
|
|
R0727:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0759:Sned1
|
UTSW |
1 |
93,200,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0965:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0968:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0969:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1006:Sned1
|
UTSW |
1 |
93,184,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1068:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1069:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1070:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1112:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1113:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1114:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1115:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1118:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1119:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1144:Sned1
|
UTSW |
1 |
93,208,298 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1228:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1230:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1231:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1313:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1313:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1340:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1382:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1383:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1394:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1395:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1397:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1414:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1430:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1432:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1473:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1563:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1565:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1689:Sned1
|
UTSW |
1 |
93,211,094 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1695:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1734:Sned1
|
UTSW |
1 |
93,187,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1764:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1767:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1896:Sned1
|
UTSW |
1 |
93,192,769 (GRCm39) |
missense |
probably benign |
0.16 |
|
R1916:Sned1
|
UTSW |
1 |
93,201,884 (GRCm39) |
missense |
probably null |
1.00 |
|
R1945:Sned1
|
UTSW |
1 |
93,198,960 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1972:Sned1
|
UTSW |
1 |
93,192,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1973:Sned1
|
UTSW |
1 |
93,192,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2143:Sned1
|
UTSW |
1 |
93,199,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2144:Sned1
|
UTSW |
1 |
93,199,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2145:Sned1
|
UTSW |
1 |
93,199,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2153:Sned1
|
UTSW |
1 |
93,202,379 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2273:Sned1
|
UTSW |
1 |
93,209,364 (GRCm39) |
splice site |
probably null |
|
|
R2274:Sned1
|
UTSW |
1 |
93,209,364 (GRCm39) |
splice site |
probably null |
|
|
R2275:Sned1
|
UTSW |
1 |
93,209,364 (GRCm39) |
splice site |
probably null |
|
|
R2340:Sned1
|
UTSW |
1 |
93,184,174 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3237:Sned1
|
UTSW |
1 |
93,186,725 (GRCm39) |
missense |
probably benign |
0.21 |
|
R3747:Sned1
|
UTSW |
1 |
93,189,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3879:Sned1
|
UTSW |
1 |
93,192,752 (GRCm39) |
splice site |
probably benign |
|
|
R4281:Sned1
|
UTSW |
1 |
93,213,577 (GRCm39) |
nonsense |
probably null |
|
|
R4282:Sned1
|
UTSW |
1 |
93,213,577 (GRCm39) |
nonsense |
probably null |
|
|
R4356:Sned1
|
UTSW |
1 |
93,193,113 (GRCm39) |
splice site |
probably null |
|
|
R4358:Sned1
|
UTSW |
1 |
93,202,381 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4677:Sned1
|
UTSW |
1 |
93,224,019 (GRCm39) |
unclassified |
probably benign |
|
|
R5291:Sned1
|
UTSW |
1 |
93,223,446 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5340:Sned1
|
UTSW |
1 |
93,210,479 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5542:Sned1
|
UTSW |
1 |
93,199,324 (GRCm39) |
missense |
probably benign |
|
|
R5582:Sned1
|
UTSW |
1 |
93,210,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5874:Sned1
|
UTSW |
1 |
93,193,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6159:Sned1
|
UTSW |
1 |
93,210,659 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6175:Sned1
|
UTSW |
1 |
93,203,196 (GRCm39) |
splice site |
probably null |
|
|
R6445:Sned1
|
UTSW |
1 |
93,211,318 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6631:Sned1
|
UTSW |
1 |
93,209,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7018:Sned1
|
UTSW |
1 |
93,212,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7035:Sned1
|
UTSW |
1 |
93,189,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7047:Sned1
|
UTSW |
1 |
93,213,540 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R7347:Sned1
|
UTSW |
1 |
93,209,458 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7427:Sned1
|
UTSW |
1 |
93,217,080 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7581:Sned1
|
UTSW |
1 |
93,184,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7679:Sned1
|
UTSW |
1 |
93,163,760 (GRCm39) |
missense |
unknown |
|
|
R7899:Sned1
|
UTSW |
1 |
93,201,804 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8093:Sned1
|
UTSW |
1 |
93,202,387 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8124:Sned1
|
UTSW |
1 |
93,210,711 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8489:Sned1
|
UTSW |
1 |
93,210,978 (GRCm39) |
nonsense |
probably null |
|
|
R9012:Sned1
|
UTSW |
1 |
93,212,320 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9290:Sned1
|
UTSW |
1 |
93,199,385 (GRCm39) |
nonsense |
probably null |
|
|
R9560:Sned1
|
UTSW |
1 |
93,202,110 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9775:Sned1
|
UTSW |
1 |
93,199,604 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0025:Sned1
|
UTSW |
1 |
93,189,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Sned1
|
UTSW |
1 |
93,186,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Sned1
|
UTSW |
1 |
93,213,542 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCATCCTCTTGCTGGACAAGCTAC -3'
(R):5'- TCCTGAAAAGCCTGACCAAGTGTG -3'
Sequencing Primer
(F):5'- TTGCTGGACAAGCTACTCAGAG -3'
(R):5'- GCCTATCCAGGGACAACAGAG -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation