Incidental Mutation 'R5068:Chd6'
| ID |
388414 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Chd6
|
| Ensembl Gene |
ENSMUSG00000057133 |
| Gene Name |
chromodomain helicase DNA binding protein 6 |
| Synonyms |
5430439G14Rik, 6330406J24Rik |
| MMRRC Submission |
042658-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.745)
|
| Stock # |
R5068 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
160788898-160950995 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 160808289 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Isoleucine
at position 1642
(L1642I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000042291
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039782]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000039782
AA Change: L1642I
PolyPhen 2
Score 0.539 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000042291
Gene: ENSMUSG00000057133
AA Change: L1642I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
86 |
106 |
N/A |
INTRINSIC |
|
low complexity region
|
113 |
143 |
N/A |
INTRINSIC |
|
low complexity region
|
214 |
229 |
N/A |
INTRINSIC |
|
CHROMO
|
289 |
355 |
1.35e-4 |
SMART |
|
CHROMO
|
372 |
430 |
3.48e-7 |
SMART |
|
DEXDc
|
456 |
658 |
1.73e-39 |
SMART |
|
HELICc
|
812 |
896 |
3.84e-23 |
SMART |
|
low complexity region
|
1080 |
1094 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1108 |
1153 |
4e-23 |
BLAST |
|
SANT
|
1445 |
1504 |
1.51e0 |
SMART |
|
low complexity region
|
1866 |
1875 |
N/A |
INTRINSIC |
|
low complexity region
|
2048 |
2057 |
N/A |
INTRINSIC |
|
low complexity region
|
2130 |
2140 |
N/A |
INTRINSIC |
|
low complexity region
|
2277 |
2290 |
N/A |
INTRINSIC |
|
low complexity region
|
2333 |
2349 |
N/A |
INTRINSIC |
|
low complexity region
|
2437 |
2446 |
N/A |
INTRINSIC |
|
low complexity region
|
2539 |
2563 |
N/A |
INTRINSIC |
|
low complexity region
|
2652 |
2659 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000137152
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000143081
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a member of the chromodomain/helicase/DNA-binding domain family of chromatin remodeling enzymes. This protein has been found to be specifically involved in transcription initiation and elongation. Homozygous knockout mice exhibit impaired motor coordination. A pseudogene has been identified on chromosome 8. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014]
PHENOTYPE: Homozygous null mice display impaired coordination that is not due to muscle weakness or bradykinesia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 110 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3425401B19Rik |
A |
G |
14: 32,383,749 (GRCm39) |
S739P |
possibly damaging |
Het |
| 6030468B19Rik |
A |
G |
11: 117,693,701 (GRCm39) |
Y56C |
possibly damaging |
Het |
| Actn2 |
A |
G |
13: 12,303,408 (GRCm39) |
I464T |
possibly damaging |
Het |
| Add2 |
T |
A |
6: 86,084,440 (GRCm39) |
L496Q |
probably damaging |
Het |
| Akt1s1 |
T |
C |
7: 44,499,432 (GRCm39) |
|
probably null |
Het |
| Als2 |
G |
T |
1: 59,250,433 (GRCm39) |
P437Q |
probably benign |
Het |
| Ankar |
T |
C |
1: 72,719,369 (GRCm39) |
|
probably null |
Het |
| Ankrd17 |
T |
C |
5: 90,402,667 (GRCm39) |
R1464G |
probably damaging |
Het |
| Ankrd24 |
T |
C |
10: 81,475,699 (GRCm39) |
S121P |
possibly damaging |
Het |
| Arvcf |
A |
G |
16: 18,217,736 (GRCm39) |
Y412C |
probably damaging |
Het |
| Birc6 |
C |
T |
17: 74,872,967 (GRCm39) |
R409C |
probably damaging |
Het |
| Bnip3l |
T |
C |
14: 67,237,081 (GRCm39) |
E57G |
possibly damaging |
Het |
| Calcoco1 |
A |
G |
15: 102,619,527 (GRCm39) |
L354P |
probably damaging |
Het |
| Cc2d1b |
T |
C |
4: 108,480,661 (GRCm39) |
V27A |
possibly damaging |
Het |
| Cdc37 |
T |
C |
9: 21,061,099 (GRCm39) |
T19A |
probably damaging |
Het |
| Cep152 |
T |
C |
2: 125,413,736 (GRCm39) |
I1199V |
probably benign |
Het |
| Chst13 |
T |
C |
6: 90,286,551 (GRCm39) |
E137G |
possibly damaging |
Het |
| Cnrip1 |
A |
G |
11: 17,004,687 (GRCm39) |
D79G |
probably damaging |
Het |
| Dars2 |
A |
T |
1: 160,869,483 (GRCm39) |
C589S |
probably benign |
Het |
| Dhx15 |
T |
G |
5: 52,327,409 (GRCm39) |
I102L |
possibly damaging |
Het |
| Dip2a |
A |
G |
10: 76,153,877 (GRCm39) |
L151P |
possibly damaging |
Het |
| Dlc1 |
T |
C |
8: 37,405,184 (GRCm39) |
T202A |
probably benign |
Het |
| Dlg1 |
G |
T |
16: 31,503,113 (GRCm39) |
|
probably null |
Het |
| Dlgap4 |
T |
C |
2: 156,549,031 (GRCm39) |
F464L |
probably benign |
Het |
| Dnah3 |
T |
C |
7: 119,632,013 (GRCm39) |
H1314R |
probably benign |
Het |
| Dsp |
A |
C |
13: 38,381,099 (GRCm39) |
T2615P |
possibly damaging |
Het |
| Dthd1 |
C |
A |
5: 62,976,059 (GRCm39) |
D244E |
probably benign |
Het |
| Dtl |
A |
T |
1: 191,300,485 (GRCm39) |
D126E |
probably damaging |
Het |
| Ell2 |
A |
G |
13: 75,911,737 (GRCm39) |
N341S |
probably benign |
Het |
| Enpp2 |
T |
C |
15: 54,727,450 (GRCm39) |
Y513C |
probably damaging |
Het |
| Erbb4 |
A |
T |
1: 68,083,061 (GRCm39) |
|
probably null |
Het |
| Erc2 |
A |
T |
14: 28,024,900 (GRCm39) |
H593L |
possibly damaging |
Het |
| Ercc6 |
T |
C |
14: 32,292,020 (GRCm39) |
V1128A |
probably benign |
Het |
| Fyn |
A |
G |
10: 39,402,839 (GRCm39) |
K204E |
probably damaging |
Het |
| Gm4847 |
A |
T |
1: 166,465,953 (GRCm39) |
F212Y |
possibly damaging |
Het |
| Gpc5 |
T |
C |
14: 115,654,676 (GRCm39) |
*499R |
probably null |
Het |
| Hcn4 |
T |
C |
9: 58,767,304 (GRCm39) |
L955P |
unknown |
Het |
| Hook2 |
C |
A |
8: 85,720,028 (GRCm39) |
L111I |
possibly damaging |
Het |
| Hook3 |
C |
T |
8: 26,585,785 (GRCm39) |
|
probably null |
Het |
| Hvcn1 |
T |
C |
5: 122,371,544 (GRCm39) |
F28S |
probably damaging |
Het |
| Igkv6-32 |
A |
G |
6: 70,051,267 (GRCm39) |
F30L |
possibly damaging |
Het |
| Inpp5b |
G |
A |
4: 124,636,442 (GRCm39) |
|
probably null |
Het |
| Itgb2 |
G |
A |
10: 77,384,595 (GRCm39) |
A239T |
probably damaging |
Het |
| Kcnrg |
T |
C |
14: 61,845,266 (GRCm39) |
L102P |
probably damaging |
Het |
| Kif16b |
A |
T |
2: 142,553,627 (GRCm39) |
M1068K |
probably benign |
Het |
| Kifc3 |
T |
C |
8: 95,836,844 (GRCm39) |
R109G |
possibly damaging |
Het |
| Klhl28 |
A |
T |
12: 65,004,486 (GRCm39) |
M9K |
probably benign |
Het |
| Kptn |
T |
C |
7: 15,857,027 (GRCm39) |
Y172H |
probably damaging |
Het |
| Mib1 |
A |
G |
18: 10,793,002 (GRCm39) |
E646G |
probably damaging |
Het |
| Mmp14 |
T |
A |
14: 54,676,570 (GRCm39) |
Y372N |
probably damaging |
Het |
| Mrc1 |
T |
A |
2: 14,311,327 (GRCm39) |
M868K |
probably benign |
Het |
| Mterf1a |
T |
C |
5: 3,941,854 (GRCm39) |
N5D |
probably benign |
Het |
| Muc5b |
T |
C |
7: 141,412,345 (GRCm39) |
S1764P |
unknown |
Het |
| Myo9b |
T |
C |
8: 71,801,699 (GRCm39) |
Y1275H |
probably damaging |
Het |
| Nek1 |
T |
C |
8: 61,469,330 (GRCm39) |
I129T |
probably damaging |
Het |
| Net1 |
G |
A |
13: 3,936,740 (GRCm39) |
A221V |
probably benign |
Het |
| Nuak2 |
A |
T |
1: 132,259,509 (GRCm39) |
D429V |
probably benign |
Het |
| Nup98 |
T |
C |
7: 101,794,862 (GRCm39) |
T882A |
probably benign |
Het |
| Or11g2 |
T |
A |
14: 50,856,197 (GRCm39) |
C173S |
probably damaging |
Het |
| Or11h4 |
C |
A |
14: 50,974,531 (GRCm39) |
L29F |
probably benign |
Het |
| Or52ab4 |
A |
T |
7: 102,987,229 (GRCm39) |
|
probably null |
Het |
| Or52h1 |
T |
A |
7: 103,829,448 (GRCm39) |
S56C |
probably damaging |
Het |
| Or8b42 |
T |
C |
9: 38,341,760 (GRCm39) |
Y61H |
probably damaging |
Het |
| Otx1 |
C |
A |
11: 21,947,037 (GRCm39) |
A91S |
probably damaging |
Het |
| Pcdh7 |
T |
C |
5: 57,879,508 (GRCm39) |
V1021A |
probably damaging |
Het |
| Pclo |
G |
C |
5: 14,729,087 (GRCm39) |
|
probably benign |
Het |
| Pds5a |
A |
C |
5: 65,772,615 (GRCm39) |
D1329E |
probably damaging |
Het |
| Pex5 |
A |
G |
6: 124,390,555 (GRCm39) |
S97P |
probably benign |
Het |
| Pias3 |
A |
G |
3: 96,611,171 (GRCm39) |
K431E |
probably damaging |
Het |
| Piwil1 |
T |
C |
5: 128,818,678 (GRCm39) |
S158P |
probably damaging |
Het |
| Plxnc1 |
A |
T |
10: 94,635,239 (GRCm39) |
I1329N |
possibly damaging |
Het |
| Pnkp |
C |
T |
7: 44,511,827 (GRCm39) |
S113L |
probably damaging |
Het |
| Pnpla1 |
T |
A |
17: 29,098,397 (GRCm39) |
|
probably null |
Het |
| Prdm10 |
T |
C |
9: 31,270,343 (GRCm39) |
Y827H |
probably damaging |
Het |
| Prss3b |
A |
C |
6: 41,009,370 (GRCm39) |
Y155D |
probably benign |
Het |
| Psma2 |
G |
A |
13: 14,790,613 (GRCm39) |
V20I |
probably benign |
Het |
| Pwwp4a |
T |
C |
X: 72,171,577 (GRCm39) |
I323T |
probably damaging |
Het |
| Rgl3 |
A |
G |
9: 21,899,340 (GRCm39) |
|
probably null |
Het |
| Rnf17 |
T |
C |
14: 56,743,385 (GRCm39) |
V1317A |
probably damaging |
Het |
| Rpp40 |
T |
C |
13: 36,082,681 (GRCm39) |
N254D |
probably benign |
Het |
| Scin |
T |
A |
12: 40,174,699 (GRCm39) |
H128L |
probably damaging |
Het |
| Sh3bp2 |
A |
T |
5: 34,714,311 (GRCm39) |
M225L |
probably benign |
Het |
| Shisa9 |
C |
A |
16: 12,085,412 (GRCm39) |
H324Q |
possibly damaging |
Het |
| Sipa1l1 |
A |
G |
12: 82,484,601 (GRCm39) |
D1585G |
probably damaging |
Het |
| Slc11a1 |
G |
A |
1: 74,424,343 (GRCm39) |
A434T |
probably damaging |
Het |
| Slc5a8 |
A |
T |
10: 88,722,460 (GRCm39) |
I98F |
possibly damaging |
Het |
| Slc6a13 |
T |
C |
6: 121,310,301 (GRCm39) |
L320P |
probably damaging |
Het |
| Spats2l |
A |
G |
1: 57,982,380 (GRCm39) |
T421A |
probably benign |
Het |
| Spryd3 |
A |
T |
15: 102,037,046 (GRCm39) |
D207E |
probably benign |
Het |
| Srrt |
T |
C |
5: 137,294,803 (GRCm39) |
N392S |
possibly damaging |
Het |
| Stk36 |
G |
T |
1: 74,661,504 (GRCm39) |
R510S |
probably benign |
Het |
| Sucnr1 |
A |
G |
3: 59,994,288 (GRCm39) |
Y272C |
probably damaging |
Het |
| Taar7b |
T |
G |
10: 23,876,359 (GRCm39) |
S175A |
probably benign |
Het |
| Tmem131 |
A |
G |
1: 36,893,986 (GRCm39) |
I139T |
probably damaging |
Het |
| Tph2 |
T |
A |
10: 114,987,079 (GRCm39) |
Y237F |
probably benign |
Het |
| Trim35 |
C |
T |
14: 66,546,421 (GRCm39) |
|
probably benign |
Het |
| Tsc22d1 |
T |
C |
14: 76,655,750 (GRCm39) |
I661T |
probably benign |
Het |
| Ttc27 |
T |
A |
17: 75,106,337 (GRCm39) |
H541Q |
probably damaging |
Het |
| Uap1 |
G |
T |
1: 169,989,032 (GRCm39) |
P130Q |
probably damaging |
Het |
| Ube3c |
T |
C |
5: 29,806,352 (GRCm39) |
|
probably null |
Het |
| Umad1 |
A |
T |
6: 8,401,157 (GRCm39) |
|
probably null |
Het |
| Usp34 |
T |
C |
11: 23,410,665 (GRCm39) |
V2705A |
possibly damaging |
Het |
| Vps13a |
T |
C |
19: 16,723,422 (GRCm39) |
S259G |
probably benign |
Het |
| Vwa7 |
G |
A |
17: 35,243,166 (GRCm39) |
V615I |
probably benign |
Het |
| Wdfy3 |
T |
C |
5: 102,042,803 (GRCm39) |
T1983A |
probably benign |
Het |
| Wdr24 |
T |
G |
17: 26,044,753 (GRCm39) |
F203V |
possibly damaging |
Het |
| Xlr4c |
T |
A |
X: 72,282,290 (GRCm39) |
K121M |
probably damaging |
Het |
| Zfc3h1 |
T |
A |
10: 115,254,688 (GRCm39) |
C1427* |
probably null |
Het |
| Zfp282 |
A |
C |
6: 47,854,637 (GRCm39) |
Q11P |
probably benign |
Het |
| Zfp750 |
T |
A |
11: 121,403,021 (GRCm39) |
T576S |
probably benign |
Het |
|
| Other mutations in Chd6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00837:Chd6
|
APN |
2 |
160,883,999 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00899:Chd6
|
APN |
2 |
160,871,218 (GRCm39) |
splice site |
probably benign |
|
|
IGL01104:Chd6
|
APN |
2 |
160,803,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01295:Chd6
|
APN |
2 |
160,830,290 (GRCm39) |
splice site |
probably benign |
|
|
IGL01717:Chd6
|
APN |
2 |
160,807,179 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL01795:Chd6
|
APN |
2 |
160,803,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01814:Chd6
|
APN |
2 |
160,901,849 (GRCm39) |
missense |
probably benign |
0.25 |
|
IGL02016:Chd6
|
APN |
2 |
160,825,598 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02104:Chd6
|
APN |
2 |
160,819,432 (GRCm39) |
missense |
probably benign |
|
|
IGL02158:Chd6
|
APN |
2 |
160,868,212 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL02313:Chd6
|
APN |
2 |
160,807,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02472:Chd6
|
APN |
2 |
160,826,372 (GRCm39) |
splice site |
probably benign |
|
|
IGL02522:Chd6
|
APN |
2 |
160,807,716 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02626:Chd6
|
APN |
2 |
160,881,270 (GRCm39) |
splice site |
probably benign |
|
|
IGL02727:Chd6
|
APN |
2 |
160,811,383 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02738:Chd6
|
APN |
2 |
160,807,618 (GRCm39) |
missense |
probably benign |
0.45 |
|
IGL02743:Chd6
|
APN |
2 |
160,802,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02800:Chd6
|
APN |
2 |
160,826,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02811:Chd6
|
APN |
2 |
160,832,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02850:Chd6
|
APN |
2 |
160,861,536 (GRCm39) |
nonsense |
probably null |
|
|
IGL02979:Chd6
|
APN |
2 |
160,808,090 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL02993:Chd6
|
APN |
2 |
160,894,304 (GRCm39) |
splice site |
probably benign |
|
|
IGL03277:Chd6
|
APN |
2 |
160,824,981 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL03346:Chd6
|
APN |
2 |
160,802,282 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03357:Chd6
|
APN |
2 |
160,859,936 (GRCm39) |
splice site |
probably benign |
|
|
IGL03134:Chd6
|
UTSW |
2 |
160,807,403 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R0106:Chd6
|
UTSW |
2 |
160,809,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0106:Chd6
|
UTSW |
2 |
160,809,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0212:Chd6
|
UTSW |
2 |
160,894,767 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0363:Chd6
|
UTSW |
2 |
160,856,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0399:Chd6
|
UTSW |
2 |
160,894,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0511:Chd6
|
UTSW |
2 |
160,834,111 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0771:Chd6
|
UTSW |
2 |
160,861,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1147:Chd6
|
UTSW |
2 |
160,832,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1147:Chd6
|
UTSW |
2 |
160,832,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1184:Chd6
|
UTSW |
2 |
160,872,722 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1277:Chd6
|
UTSW |
2 |
160,809,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1396:Chd6
|
UTSW |
2 |
160,825,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1647:Chd6
|
UTSW |
2 |
160,883,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1648:Chd6
|
UTSW |
2 |
160,883,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1745:Chd6
|
UTSW |
2 |
160,823,587 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1766:Chd6
|
UTSW |
2 |
160,808,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1871:Chd6
|
UTSW |
2 |
160,832,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1928:Chd6
|
UTSW |
2 |
160,809,920 (GRCm39) |
splice site |
probably benign |
|
|
R1973:Chd6
|
UTSW |
2 |
160,808,307 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2200:Chd6
|
UTSW |
2 |
160,825,673 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2340:Chd6
|
UTSW |
2 |
160,807,679 (GRCm39) |
frame shift |
probably null |
|
|
R2341:Chd6
|
UTSW |
2 |
160,807,679 (GRCm39) |
frame shift |
probably null |
|
|
R2519:Chd6
|
UTSW |
2 |
160,871,796 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R2919:Chd6
|
UTSW |
2 |
160,809,800 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3025:Chd6
|
UTSW |
2 |
160,808,472 (GRCm39) |
small deletion |
probably benign |
|
|
R3426:Chd6
|
UTSW |
2 |
160,832,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3427:Chd6
|
UTSW |
2 |
160,832,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4042:Chd6
|
UTSW |
2 |
160,830,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4273:Chd6
|
UTSW |
2 |
160,803,211 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4360:Chd6
|
UTSW |
2 |
160,791,776 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R4399:Chd6
|
UTSW |
2 |
160,807,238 (GRCm39) |
missense |
probably benign |
|
|
R4458:Chd6
|
UTSW |
2 |
160,871,796 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4583:Chd6
|
UTSW |
2 |
160,856,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4625:Chd6
|
UTSW |
2 |
160,811,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4740:Chd6
|
UTSW |
2 |
160,812,103 (GRCm39) |
missense |
probably benign |
|
|
R4765:Chd6
|
UTSW |
2 |
160,808,164 (GRCm39) |
nonsense |
probably null |
|
|
R4779:Chd6
|
UTSW |
2 |
160,791,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4877:Chd6
|
UTSW |
2 |
160,871,219 (GRCm39) |
splice site |
probably benign |
|
|
R5215:Chd6
|
UTSW |
2 |
160,791,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5275:Chd6
|
UTSW |
2 |
160,811,283 (GRCm39) |
missense |
probably benign |
|
|
R5405:Chd6
|
UTSW |
2 |
160,807,310 (GRCm39) |
missense |
probably benign |
|
|
R5598:Chd6
|
UTSW |
2 |
160,856,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5693:Chd6
|
UTSW |
2 |
160,807,185 (GRCm39) |
missense |
probably benign |
|
|
R5697:Chd6
|
UTSW |
2 |
160,859,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5715:Chd6
|
UTSW |
2 |
160,791,798 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5759:Chd6
|
UTSW |
2 |
160,825,682 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5761:Chd6
|
UTSW |
2 |
160,798,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5761:Chd6
|
UTSW |
2 |
160,798,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5954:Chd6
|
UTSW |
2 |
160,807,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6025:Chd6
|
UTSW |
2 |
160,807,502 (GRCm39) |
missense |
probably benign |
|
|
R6104:Chd6
|
UTSW |
2 |
160,856,052 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6247:Chd6
|
UTSW |
2 |
160,791,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6393:Chd6
|
UTSW |
2 |
160,821,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6452:Chd6
|
UTSW |
2 |
160,807,418 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6468:Chd6
|
UTSW |
2 |
160,854,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6784:Chd6
|
UTSW |
2 |
160,808,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6803:Chd6
|
UTSW |
2 |
160,802,279 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R6869:Chd6
|
UTSW |
2 |
160,807,650 (GRCm39) |
missense |
probably benign |
|
|
R6895:Chd6
|
UTSW |
2 |
160,830,260 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6925:Chd6
|
UTSW |
2 |
160,855,047 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7061:Chd6
|
UTSW |
2 |
160,867,885 (GRCm39) |
nonsense |
probably null |
|
|
R7064:Chd6
|
UTSW |
2 |
160,791,983 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7248:Chd6
|
UTSW |
2 |
160,803,199 (GRCm39) |
nonsense |
probably null |
|
|
R7287:Chd6
|
UTSW |
2 |
160,850,312 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7431:Chd6
|
UTSW |
2 |
160,868,248 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7486:Chd6
|
UTSW |
2 |
160,791,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7509:Chd6
|
UTSW |
2 |
160,855,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7699:Chd6
|
UTSW |
2 |
160,867,863 (GRCm39) |
missense |
probably benign |
0.13 |
|
R7748:Chd6
|
UTSW |
2 |
160,808,539 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7785:Chd6
|
UTSW |
2 |
160,812,095 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8002:Chd6
|
UTSW |
2 |
160,832,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8261:Chd6
|
UTSW |
2 |
160,799,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8317:Chd6
|
UTSW |
2 |
160,832,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8388:Chd6
|
UTSW |
2 |
160,861,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8865:Chd6
|
UTSW |
2 |
160,862,989 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8867:Chd6
|
UTSW |
2 |
160,862,989 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8996:Chd6
|
UTSW |
2 |
160,823,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9091:Chd6
|
UTSW |
2 |
160,871,793 (GRCm39) |
nonsense |
probably null |
|
|
R9270:Chd6
|
UTSW |
2 |
160,871,793 (GRCm39) |
nonsense |
probably null |
|
|
R9310:Chd6
|
UTSW |
2 |
160,881,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9367:Chd6
|
UTSW |
2 |
160,871,784 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9438:Chd6
|
UTSW |
2 |
160,799,078 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9756:Chd6
|
UTSW |
2 |
160,802,259 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Chd6
|
UTSW |
2 |
160,808,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTTCTCCAAAGACTCAGGC -3'
(R):5'- TGGGAAACATGATCGAGACCTG -3'
Sequencing Primer
(F):5'- GACTCAGGCAGCAAGTTTTC -3'
(R):5'- ACATGATCGAGACCTGCTCATTGG -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation