Incidental Mutation 'R5022:Mdga2'
| ID |
389278 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mdga2
|
| Ensembl Gene |
ENSMUSG00000034912 |
| Gene Name |
MAM domain containing glycosylphosphatidylinositol anchor 2 |
| Synonyms |
Adp, 6720489L24Rik, Mamdc1, 9330209L04Rik, Mdga2 |
| MMRRC Submission |
042613-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5022 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
12 |
| Chromosomal Location |
66466060-67222549 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 66470760 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Tyrosine
at position 100
(C100Y)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109575
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037181]
[ENSMUST00000113942]
[ENSMUST00000222167]
[ENSMUST00000222623]
[ENSMUST00000222987]
[ENSMUST00000223141]
|
| AlphaFold |
P60755 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000037181
|
| SMART Domains |
Protein: ENSMUSP00000046761
Gene: ENSMUSG00000034912
| Domain | Start | End | E-Value | Type |
|---|
|
IGc2
|
122 |
186 |
1.38e-15 |
SMART |
|
IG
|
213 |
307 |
1.79e0 |
SMART |
|
IGc2
|
324 |
386 |
1.56e-14 |
SMART |
|
IGc2
|
419 |
493 |
4.43e-5 |
SMART |
|
low complexity region
|
495 |
507 |
N/A |
INTRINSIC |
|
IGc2
|
525 |
591 |
1.97e-11 |
SMART |
|
IG_like
|
621 |
687 |
2.5e0 |
SMART |
|
Blast:FN3
|
707 |
795 |
4e-40 |
BLAST |
|
MAM
|
812 |
990 |
3.4e-49 |
SMART |
|
transmembrane domain
|
999 |
1021 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000101379
|
| SMART Domains |
Protein: ENSMUSP00000098930
Gene: ENSMUSG00000034912
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
SCOP:d1cs6a1
|
40 |
72 |
2e-5 |
SMART |
|
Blast:IG
|
47 |
72 |
9e-11 |
BLAST |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000113942
AA Change: C100Y
PolyPhen 2
Score 0.827 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000109575
Gene: ENSMUSG00000034912
AA Change: C100Y
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
60 |
91 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000178814
|
| SMART Domains |
Protein: ENSMUSP00000137608
Gene: ENSMUSG00000034912
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
IGc2
|
53 |
117 |
1.38e-15 |
SMART |
|
IG
|
144 |
238 |
1.79e0 |
SMART |
|
IGc2
|
255 |
317 |
1.56e-14 |
SMART |
|
IGc2
|
350 |
424 |
4.43e-5 |
SMART |
|
low complexity region
|
426 |
438 |
N/A |
INTRINSIC |
|
IGc2
|
456 |
522 |
1.97e-11 |
SMART |
|
IG_like
|
552 |
618 |
2.5e0 |
SMART |
|
Blast:FN3
|
638 |
726 |
3e-40 |
BLAST |
|
MAM
|
736 |
914 |
1.38e-49 |
SMART |
|
transmembrane domain
|
923 |
945 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000222167
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000222623
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000222987
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000223141
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.4%
- 20x: 92.6%
|
| Validation Efficiency |
99% (110/111) |
| MGI Phenotype |
PHENOTYPE: Mice that paternally inherit an allele disrupted by transgene insertion exhibit varying degrees of abnormalities in the skull, paw, and tail. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca1 |
TCGACTGC |
T |
4: 53,041,570 (GRCm38) |
|
probably null |
Het |
| Abca15 |
T |
C |
7: 120,346,096 (GRCm38) |
I465T |
probably damaging |
Het |
| Abca3 |
C |
T |
17: 24,374,300 (GRCm38) |
R224C |
probably damaging |
Het |
| Abcb4 |
T |
A |
5: 8,909,054 (GRCm38) |
|
probably null |
Het |
| Acan |
T |
C |
7: 79,092,808 (GRCm38) |
|
probably null |
Het |
| Aebp2 |
G |
A |
6: 140,637,730 (GRCm38) |
R109Q |
possibly damaging |
Het |
| Agfg2 |
A |
T |
5: 137,660,160 (GRCm38) |
|
probably null |
Het |
| Ankib1 |
T |
A |
5: 3,734,011 (GRCm38) |
I322F |
possibly damaging |
Het |
| AW551984 |
A |
T |
9: 39,597,965 (GRCm38) |
N293K |
probably benign |
Het |
| BC028528 |
T |
A |
3: 95,888,823 (GRCm38) |
|
probably benign |
Het |
| Bicc1 |
A |
G |
10: 70,947,883 (GRCm38) |
S393P |
possibly damaging |
Het |
| Birc6 |
A |
G |
17: 74,692,332 (GRCm38) |
Y4656C |
probably damaging |
Het |
| Bmp3 |
A |
G |
5: 98,872,824 (GRCm38) |
R369G |
probably damaging |
Het |
| C1d |
T |
A |
11: 17,266,674 (GRCm38) |
N135K |
probably benign |
Het |
| Ccdc148 |
G |
A |
2: 58,827,632 (GRCm38) |
A453V |
probably damaging |
Het |
| Cd163 |
C |
T |
6: 124,325,288 (GRCm38) |
T937I |
probably damaging |
Het |
| Celf2 |
C |
T |
2: 6,607,847 (GRCm38) |
|
probably benign |
Het |
| Chga |
T |
C |
12: 102,562,837 (GRCm38) |
W358R |
probably damaging |
Het |
| Clec4b2 |
A |
T |
6: 123,200,956 (GRCm38) |
S77C |
probably null |
Het |
| Crim1 |
T |
C |
17: 78,280,129 (GRCm38) |
V221A |
possibly damaging |
Het |
| D630003M21Rik |
A |
T |
2: 158,217,633 (GRCm38) |
S116T |
probably damaging |
Het |
| Dlg5 |
T |
C |
14: 24,136,622 (GRCm38) |
E1847G |
probably damaging |
Het |
| Dmxl1 |
T |
A |
18: 49,895,127 (GRCm38) |
I2206K |
probably damaging |
Het |
| Dusp7 |
T |
A |
9: 106,373,741 (GRCm38) |
L355Q |
probably damaging |
Het |
| Exd2 |
T |
A |
12: 80,496,790 (GRCm38) |
N582K |
probably damaging |
Het |
| Fbln1 |
G |
A |
15: 85,237,626 (GRCm38) |
S316N |
probably damaging |
Het |
| Fchsd1 |
A |
G |
18: 37,964,810 (GRCm38) |
I340T |
possibly damaging |
Het |
| Fn1 |
T |
C |
1: 71,624,179 (GRCm38) |
Y1050C |
probably damaging |
Het |
| Fsip2 |
A |
G |
2: 82,979,429 (GRCm38) |
I2031V |
probably benign |
Het |
| Gm10803 |
A |
C |
2: 93,564,172 (GRCm38) |
L96F |
probably damaging |
Het |
| Gm12169 |
T |
A |
11: 46,528,532 (GRCm38) |
D58E |
probably damaging |
Het |
| Gm14569 |
T |
C |
X: 36,430,817 (GRCm38) |
D1413G |
probably benign |
Het |
| Gm15455 |
T |
C |
1: 33,837,351 (GRCm38) |
|
noncoding transcript |
Het |
| Gm1818 |
G |
C |
12: 48,555,535 (GRCm38) |
|
noncoding transcript |
Het |
| Gm4907 |
G |
A |
X: 23,907,241 (GRCm38) |
G327E |
probably damaging |
Het |
| Gm5039 |
T |
C |
12: 88,321,301 (GRCm38) |
I61V |
probably benign |
Het |
| Gm5420 |
A |
T |
10: 21,691,727 (GRCm38) |
|
noncoding transcript |
Het |
| Gm6803 |
A |
T |
12: 88,018,711 (GRCm38) |
S21T |
unknown |
Het |
| Gm7104 |
A |
T |
12: 88,285,759 (GRCm38) |
|
noncoding transcript |
Het |
| Gp2 |
A |
G |
7: 119,449,114 (GRCm38) |
I427T |
probably damaging |
Het |
| Gpc4 |
G |
A |
X: 52,074,563 (GRCm38) |
R148C |
probably damaging |
Het |
| Gpr142 |
A |
C |
11: 114,804,388 (GRCm38) |
S60R |
probably benign |
Het |
| Helz2 |
T |
C |
2: 181,240,569 (GRCm38) |
R144G |
probably benign |
Het |
| Herc1 |
A |
T |
9: 66,470,326 (GRCm38) |
K3458M |
possibly damaging |
Het |
| Hnf4g |
G |
T |
3: 3,644,587 (GRCm38) |
A144S |
probably damaging |
Het |
| Irs2 |
A |
C |
8: 10,987,012 (GRCm38) |
*1322G |
probably null |
Het |
| Keg1 |
A |
G |
19: 12,719,157 (GRCm38) |
N288S |
probably damaging |
Het |
| Kif19a |
G |
A |
11: 114,767,227 (GRCm38) |
M37I |
probably benign |
Het |
| Klhl1 |
G |
A |
14: 96,136,706 (GRCm38) |
P635S |
probably benign |
Het |
| Klk14 |
G |
A |
7: 43,692,077 (GRCm38) |
C51Y |
probably damaging |
Het |
| Lsm11 |
T |
C |
11: 45,944,839 (GRCm38) |
D25G |
probably damaging |
Het |
| Manea |
A |
T |
4: 26,336,630 (GRCm38) |
Y215* |
probably null |
Het |
| Mthfd1 |
T |
G |
12: 76,294,374 (GRCm38) |
V480G |
probably damaging |
Het |
| Mthfd1 |
T |
A |
12: 76,301,328 (GRCm38) |
M582K |
probably damaging |
Het |
| Myh7b |
G |
C |
2: 155,632,373 (GRCm38) |
R1669S |
possibly damaging |
Het |
| Nanos1 |
T |
C |
19: 60,756,980 (GRCm38) |
Y239H |
probably damaging |
Het |
| Nat8 |
G |
A |
6: 85,830,857 (GRCm38) |
T98I |
possibly damaging |
Het |
| Ndufs3 |
C |
A |
2: 90,898,660 (GRCm38) |
A161S |
probably benign |
Het |
| Nexmif |
A |
T |
X: 104,087,350 (GRCm38) |
N320K |
probably damaging |
Het |
| Olfr1216 |
A |
G |
2: 89,014,043 (GRCm38) |
V7A |
probably damaging |
Het |
| Olfr1228 |
C |
T |
2: 89,249,417 (GRCm38) |
M92I |
probably benign |
Het |
| Olfr164 |
A |
T |
16: 19,286,059 (GRCm38) |
V228D |
probably damaging |
Het |
| Olfr239 |
T |
C |
17: 33,199,777 (GRCm38) |
F239S |
probably damaging |
Het |
| Olfr457 |
A |
T |
6: 42,471,287 (GRCm38) |
V297E |
possibly damaging |
Het |
| Olfr589 |
G |
A |
7: 103,155,735 (GRCm38) |
P4L |
probably benign |
Het |
| Olfr727 |
T |
C |
14: 50,127,012 (GRCm38) |
V145A |
possibly damaging |
Het |
| Olfr822 |
T |
C |
10: 130,074,593 (GRCm38) |
L61P |
probably damaging |
Het |
| Pcdhb14 |
T |
A |
18: 37,450,170 (GRCm38) |
N776K |
probably benign |
Het |
| Pip5k1c |
G |
A |
10: 81,310,889 (GRCm38) |
|
probably null |
Het |
| Plk4 |
G |
A |
3: 40,802,077 (GRCm38) |
|
probably null |
Het |
| Prmt8 |
A |
G |
6: 127,711,163 (GRCm38) |
Y231H |
possibly damaging |
Het |
| Prpf4b |
T |
C |
13: 34,883,599 (GRCm38) |
|
probably benign |
Het |
| Ptpn21 |
G |
A |
12: 98,679,407 (GRCm38) |
R1091C |
probably damaging |
Het |
| Pwwp2b |
C |
T |
7: 139,255,578 (GRCm38) |
P312S |
possibly damaging |
Het |
| Rad21 |
A |
T |
15: 51,966,706 (GRCm38) |
I503K |
probably benign |
Het |
| Rai14 |
A |
G |
15: 10,574,506 (GRCm38) |
S789P |
probably damaging |
Het |
| Rbm26 |
C |
T |
14: 105,144,252 (GRCm38) |
D486N |
probably damaging |
Het |
| Rnf20 |
A |
G |
4: 49,642,016 (GRCm38) |
|
probably benign |
Het |
| Ros1 |
A |
G |
10: 52,124,075 (GRCm38) |
V1118A |
possibly damaging |
Het |
| Sema3d |
A |
C |
5: 12,584,956 (GRCm38) |
Y663S |
probably damaging |
Het |
| Serpina6 |
A |
G |
12: 103,651,712 (GRCm38) |
W281R |
probably damaging |
Het |
| Slc8a3 |
A |
G |
12: 81,199,558 (GRCm38) |
V900A |
probably damaging |
Het |
| Spats2l |
G |
T |
1: 57,879,556 (GRCm38) |
V30L |
probably damaging |
Het |
| Spg21 |
A |
G |
9: 65,475,949 (GRCm38) |
D139G |
probably damaging |
Het |
| Sun3 |
T |
C |
11: 9,038,314 (GRCm38) |
T3A |
probably damaging |
Het |
| Tcrg-V1 |
T |
A |
13: 19,340,231 (GRCm38) |
S42T |
probably benign |
Het |
| Tep1 |
A |
G |
14: 50,828,999 (GRCm38) |
Y2335H |
probably benign |
Het |
| Timm21 |
C |
A |
18: 84,949,414 (GRCm38) |
V112L |
possibly damaging |
Het |
| Tlk1 |
A |
T |
2: 70,742,065 (GRCm38) |
N386K |
probably benign |
Het |
| Trappc10 |
G |
T |
10: 78,217,160 (GRCm38) |
F260L |
possibly damaging |
Het |
| Trmt112 |
T |
C |
19: 6,910,753 (GRCm38) |
V91A |
probably benign |
Het |
| Ucp2 |
A |
T |
7: 100,498,372 (GRCm38) |
N186I |
possibly damaging |
Het |
| Vmn1r119 |
A |
G |
7: 21,012,320 (GRCm38) |
S46P |
probably benign |
Het |
| Vmn2r101 |
A |
T |
17: 19,611,387 (GRCm38) |
|
probably null |
Het |
| Vmn2r105 |
T |
A |
17: 20,208,414 (GRCm38) |
H800L |
probably damaging |
Het |
| Vmn2r69 |
T |
C |
7: 85,411,159 (GRCm38) |
M406V |
possibly damaging |
Het |
| Vmn2r84 |
A |
G |
10: 130,386,548 (GRCm38) |
L601P |
probably damaging |
Het |
| Vps16 |
A |
G |
2: 130,439,452 (GRCm38) |
S235G |
probably benign |
Het |
| Wap |
T |
C |
11: 6,637,339 (GRCm38) |
|
probably benign |
Het |
| Wdr11 |
A |
G |
7: 129,624,711 (GRCm38) |
I744M |
probably benign |
Het |
| Xiap |
T |
C |
X: 42,094,465 (GRCm38) |
F23L |
probably benign |
Het |
| Xkr7 |
A |
G |
2: 153,054,380 (GRCm38) |
T385A |
probably benign |
Het |
| Zfp524 |
A |
T |
7: 5,018,417 (GRCm38) |
I315F |
probably benign |
Het |
| Zfp62 |
T |
A |
11: 49,215,729 (GRCm38) |
S216T |
probably damaging |
Het |
| Znfx1 |
T |
C |
2: 167,039,826 (GRCm38) |
Y217C |
probably damaging |
Het |
|
| Other mutations in Mdga2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01343:Mdga2
|
APN |
12 |
66,723,109 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL01632:Mdga2
|
APN |
12 |
66,629,898 (GRCm38) |
splice site |
probably benign |
|
|
IGL01843:Mdga2
|
APN |
12 |
66,723,131 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
IGL02230:Mdga2
|
APN |
12 |
66,655,423 (GRCm38) |
nonsense |
probably null |
|
|
IGL02348:Mdga2
|
APN |
12 |
66,550,575 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02473:Mdga2
|
APN |
12 |
66,550,611 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
IGL02795:Mdga2
|
APN |
12 |
66,689,432 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02901:Mdga2
|
APN |
12 |
66,797,809 (GRCm38) |
splice site |
probably benign |
|
|
IGL03373:Mdga2
|
APN |
12 |
66,716,722 (GRCm38) |
missense |
probably damaging |
0.99 |
|
PIT4362001:Mdga2
|
UTSW |
12 |
66,797,768 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
PIT4377001:Mdga2
|
UTSW |
12 |
66,716,695 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0106:Mdga2
|
UTSW |
12 |
66,716,706 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0106:Mdga2
|
UTSW |
12 |
66,716,706 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0110:Mdga2
|
UTSW |
12 |
66,470,926 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R0218:Mdga2
|
UTSW |
12 |
66,655,120 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0450:Mdga2
|
UTSW |
12 |
66,470,926 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R0801:Mdga2
|
UTSW |
12 |
66,486,733 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0847:Mdga2
|
UTSW |
12 |
66,723,080 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1056:Mdga2
|
UTSW |
12 |
66,723,120 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R1086:Mdga2
|
UTSW |
12 |
66,506,102 (GRCm38) |
splice site |
probably benign |
|
|
R1335:Mdga2
|
UTSW |
12 |
66,716,742 (GRCm38) |
splice site |
probably null |
|
|
R1382:Mdga2
|
UTSW |
12 |
66,470,916 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R1490:Mdga2
|
UTSW |
12 |
66,797,756 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1521:Mdga2
|
UTSW |
12 |
66,568,926 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1556:Mdga2
|
UTSW |
12 |
66,550,593 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R1676:Mdga2
|
UTSW |
12 |
66,568,773 (GRCm38) |
nonsense |
probably null |
|
|
R1676:Mdga2
|
UTSW |
12 |
66,568,772 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1698:Mdga2
|
UTSW |
12 |
66,689,335 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R1954:Mdga2
|
UTSW |
12 |
66,486,708 (GRCm38) |
splice site |
probably benign |
|
|
R2069:Mdga2
|
UTSW |
12 |
66,568,917 (GRCm38) |
nonsense |
probably null |
|
|
R2077:Mdga2
|
UTSW |
12 |
66,655,362 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2118:Mdga2
|
UTSW |
12 |
66,868,752 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2146:Mdga2
|
UTSW |
12 |
66,868,741 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2158:Mdga2
|
UTSW |
12 |
66,689,381 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R2189:Mdga2
|
UTSW |
12 |
66,473,196 (GRCm38) |
splice site |
probably null |
|
|
R2293:Mdga2
|
UTSW |
12 |
66,568,985 (GRCm38) |
nonsense |
probably null |
|
|
R2886:Mdga2
|
UTSW |
12 |
66,506,270 (GRCm38) |
splice site |
probably benign |
|
|
R2960:Mdga2
|
UTSW |
12 |
66,629,978 (GRCm38) |
nonsense |
probably null |
|
|
R3937:Mdga2
|
UTSW |
12 |
67,221,206 (GRCm38) |
unclassified |
probably benign |
|
|
R4437:Mdga2
|
UTSW |
12 |
66,473,198 (GRCm38) |
splice site |
probably null |
|
|
R4514:Mdga2
|
UTSW |
12 |
66,716,722 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4693:Mdga2
|
UTSW |
12 |
66,797,633 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R4719:Mdga2
|
UTSW |
12 |
66,471,001 (GRCm38) |
unclassified |
probably benign |
|
|
R4744:Mdga2
|
UTSW |
12 |
66,797,727 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4756:Mdga2
|
UTSW |
12 |
66,797,653 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4781:Mdga2
|
UTSW |
12 |
66,797,622 (GRCm38) |
splice site |
probably null |
|
|
R5108:Mdga2
|
UTSW |
12 |
66,486,741 (GRCm38) |
missense |
probably benign |
0.43 |
|
R5479:Mdga2
|
UTSW |
12 |
66,655,176 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5710:Mdga2
|
UTSW |
12 |
66,506,782 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5816:Mdga2
|
UTSW |
12 |
66,655,182 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5822:Mdga2
|
UTSW |
12 |
66,655,335 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5996:Mdga2
|
UTSW |
12 |
66,797,763 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6038:Mdga2
|
UTSW |
12 |
66,630,053 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6038:Mdga2
|
UTSW |
12 |
66,630,053 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6297:Mdga2
|
UTSW |
12 |
66,506,253 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6484:Mdga2
|
UTSW |
12 |
66,630,069 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R6830:Mdga2
|
UTSW |
12 |
66,723,001 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6912:Mdga2
|
UTSW |
12 |
66,506,115 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6971:Mdga2
|
UTSW |
12 |
66,550,561 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7053:Mdga2
|
UTSW |
12 |
66,689,384 (GRCm38) |
missense |
probably benign |
0.41 |
|
R7069:Mdga2
|
UTSW |
12 |
66,486,752 (GRCm38) |
missense |
probably benign |
0.31 |
|
R7381:Mdga2
|
UTSW |
12 |
66,568,896 (GRCm38) |
missense |
probably benign |
0.44 |
|
R7474:Mdga2
|
UTSW |
12 |
66,486,761 (GRCm38) |
nonsense |
probably null |
|
|
R7559:Mdga2
|
UTSW |
12 |
66,473,229 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7581:Mdga2
|
UTSW |
12 |
66,506,255 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7596:Mdga2
|
UTSW |
12 |
66,506,123 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7745:Mdga2
|
UTSW |
12 |
66,689,351 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R7745:Mdga2
|
UTSW |
12 |
66,689,350 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7852:Mdga2
|
UTSW |
12 |
66,470,950 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R8144:Mdga2
|
UTSW |
12 |
66,655,263 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8319:Mdga2
|
UTSW |
12 |
67,221,029 (GRCm38) |
missense |
unknown |
|
|
R8715:Mdga2
|
UTSW |
12 |
66,868,752 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8977:Mdga2
|
UTSW |
12 |
66,797,635 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R9138:Mdga2
|
UTSW |
12 |
66,568,889 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R9177:Mdga2
|
UTSW |
12 |
66,470,707 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R9223:Mdga2
|
UTSW |
12 |
66,568,860 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R9248:Mdga2
|
UTSW |
12 |
66,689,452 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R9264:Mdga2
|
UTSW |
12 |
66,513,283 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9381:Mdga2
|
UTSW |
12 |
66,550,530 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R9456:Mdga2
|
UTSW |
12 |
66,568,758 (GRCm38) |
missense |
probably benign |
0.44 |
|
R9633:Mdga2
|
UTSW |
12 |
66,689,432 (GRCm38) |
missense |
probably benign |
0.00 |
|
Z1176:Mdga2
|
UTSW |
12 |
66,689,443 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1186:Mdga2
|
UTSW |
12 |
66,568,953 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGGCTTGTTTCATTGAAGGCAC -3'
(R):5'- GGCTGTTACCCTTCCTTGAAAATAC -3'
Sequencing Primer
(F):5'- AGGCACTTGGTTTCCATGGC -3'
(R):5'- TTCCTTGAAAATACTCCAAACTCGG -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation