Incidental Mutation 'R5022:Mdga2'
| ID |
389278 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mdga2
|
| Ensembl Gene |
ENSMUSG00000034912 |
| Gene Name |
MAM domain containing glycosylphosphatidylinositol anchor 2 |
| Synonyms |
6720489L24Rik, Mdga2, Adp, 9330209L04Rik, Mamdc1 |
| MMRRC Submission |
042613-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5022 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
12 |
| Chromosomal Location |
66512834-67269323 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 66517534 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Tyrosine
at position 100
(C100Y)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109575
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037181]
[ENSMUST00000113942]
[ENSMUST00000222167]
[ENSMUST00000222623]
[ENSMUST00000222987]
[ENSMUST00000223141]
|
| AlphaFold |
P60755 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000037181
|
| SMART Domains |
Protein: ENSMUSP00000046761
Gene: ENSMUSG00000034912
| Domain | Start | End | E-Value | Type |
|---|
|
IGc2
|
122 |
186 |
1.38e-15 |
SMART |
|
IG
|
213 |
307 |
1.79e0 |
SMART |
|
IGc2
|
324 |
386 |
1.56e-14 |
SMART |
|
IGc2
|
419 |
493 |
4.43e-5 |
SMART |
|
low complexity region
|
495 |
507 |
N/A |
INTRINSIC |
|
IGc2
|
525 |
591 |
1.97e-11 |
SMART |
|
IG_like
|
621 |
687 |
2.5e0 |
SMART |
|
Blast:FN3
|
707 |
795 |
4e-40 |
BLAST |
|
MAM
|
812 |
990 |
3.4e-49 |
SMART |
|
transmembrane domain
|
999 |
1021 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000101379
|
| SMART Domains |
Protein: ENSMUSP00000098930
Gene: ENSMUSG00000034912
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
SCOP:d1cs6a1
|
40 |
72 |
2e-5 |
SMART |
|
Blast:IG
|
47 |
72 |
9e-11 |
BLAST |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000113942
AA Change: C100Y
PolyPhen 2
Score 0.827 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000109575
Gene: ENSMUSG00000034912
AA Change: C100Y
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
60 |
91 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000178814
|
| SMART Domains |
Protein: ENSMUSP00000137608
Gene: ENSMUSG00000034912
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
IGc2
|
53 |
117 |
1.38e-15 |
SMART |
|
IG
|
144 |
238 |
1.79e0 |
SMART |
|
IGc2
|
255 |
317 |
1.56e-14 |
SMART |
|
IGc2
|
350 |
424 |
4.43e-5 |
SMART |
|
low complexity region
|
426 |
438 |
N/A |
INTRINSIC |
|
IGc2
|
456 |
522 |
1.97e-11 |
SMART |
|
IG_like
|
552 |
618 |
2.5e0 |
SMART |
|
Blast:FN3
|
638 |
726 |
3e-40 |
BLAST |
|
MAM
|
736 |
914 |
1.38e-49 |
SMART |
|
transmembrane domain
|
923 |
945 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000222167
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000222623
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000222987
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000223141
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.4%
- 20x: 92.6%
|
| Validation Efficiency |
99% (110/111) |
| MGI Phenotype |
PHENOTYPE: Mice that paternally inherit an allele disrupted by transgene insertion exhibit varying degrees of abnormalities in the skull, paw, and tail. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca1 |
TCGACTGC |
T |
4: 53,041,570 (GRCm39) |
|
probably null |
Het |
| Abca15 |
T |
C |
7: 119,945,319 (GRCm39) |
I465T |
probably damaging |
Het |
| Abca3 |
C |
T |
17: 24,593,274 (GRCm39) |
R224C |
probably damaging |
Het |
| Abcb4 |
T |
A |
5: 8,959,054 (GRCm39) |
|
probably null |
Het |
| Acan |
T |
C |
7: 78,742,556 (GRCm39) |
|
probably null |
Het |
| Aebp2 |
G |
A |
6: 140,583,456 (GRCm39) |
R109Q |
possibly damaging |
Het |
| Agfg2 |
A |
T |
5: 137,658,422 (GRCm39) |
|
probably null |
Het |
| Ankib1 |
T |
A |
5: 3,784,011 (GRCm39) |
I322F |
possibly damaging |
Het |
| AW551984 |
A |
T |
9: 39,509,261 (GRCm39) |
N293K |
probably benign |
Het |
| BC028528 |
T |
A |
3: 95,796,135 (GRCm39) |
|
probably benign |
Het |
| Bicc1 |
A |
G |
10: 70,783,713 (GRCm39) |
S393P |
possibly damaging |
Het |
| Birc6 |
A |
G |
17: 74,999,327 (GRCm39) |
Y4656C |
probably damaging |
Het |
| Bmp3 |
A |
G |
5: 99,020,683 (GRCm39) |
R369G |
probably damaging |
Het |
| C1d |
T |
A |
11: 17,216,674 (GRCm39) |
N135K |
probably benign |
Het |
| Ccdc148 |
G |
A |
2: 58,717,644 (GRCm39) |
A453V |
probably damaging |
Het |
| Cd163 |
C |
T |
6: 124,302,247 (GRCm39) |
T937I |
probably damaging |
Het |
| Celf2 |
C |
T |
2: 6,612,658 (GRCm39) |
|
probably benign |
Het |
| Chga |
T |
C |
12: 102,529,096 (GRCm39) |
W358R |
probably damaging |
Het |
| Clec4b2 |
A |
T |
6: 123,177,915 (GRCm39) |
S77C |
probably null |
Het |
| Crim1 |
T |
C |
17: 78,587,558 (GRCm39) |
V221A |
possibly damaging |
Het |
| D630003M21Rik |
A |
T |
2: 158,059,553 (GRCm39) |
S116T |
probably damaging |
Het |
| Dlg5 |
T |
C |
14: 24,186,690 (GRCm39) |
E1847G |
probably damaging |
Het |
| Dmxl1 |
T |
A |
18: 50,028,194 (GRCm39) |
I2206K |
probably damaging |
Het |
| Dusp7 |
T |
A |
9: 106,250,940 (GRCm39) |
L355Q |
probably damaging |
Het |
| Eif1ad15 |
T |
C |
12: 88,288,071 (GRCm39) |
I61V |
probably benign |
Het |
| Eif1ad16 |
A |
T |
12: 87,985,481 (GRCm39) |
S21T |
unknown |
Het |
| Exd2 |
T |
A |
12: 80,543,564 (GRCm39) |
N582K |
probably damaging |
Het |
| Fbln1 |
G |
A |
15: 85,121,827 (GRCm39) |
S316N |
probably damaging |
Het |
| Fchsd1 |
A |
G |
18: 38,097,863 (GRCm39) |
I340T |
possibly damaging |
Het |
| Fn1 |
T |
C |
1: 71,663,338 (GRCm39) |
Y1050C |
probably damaging |
Het |
| Fsip2 |
A |
G |
2: 82,809,773 (GRCm39) |
I2031V |
probably benign |
Het |
| Gm10803 |
A |
C |
2: 93,394,517 (GRCm39) |
L96F |
probably damaging |
Het |
| Gm14569 |
T |
C |
X: 35,694,470 (GRCm39) |
D1413G |
probably benign |
Het |
| Gm15455 |
T |
C |
1: 33,876,432 (GRCm39) |
|
noncoding transcript |
Het |
| Gm1818 |
G |
C |
12: 48,602,318 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5420 |
A |
T |
10: 21,567,626 (GRCm39) |
|
noncoding transcript |
Het |
| Gm7104 |
A |
T |
12: 88,252,529 (GRCm39) |
|
noncoding transcript |
Het |
| Gp2 |
A |
G |
7: 119,048,337 (GRCm39) |
I427T |
probably damaging |
Het |
| Gpc4 |
G |
A |
X: 51,163,440 (GRCm39) |
R148C |
probably damaging |
Het |
| Gpr142 |
A |
C |
11: 114,695,214 (GRCm39) |
S60R |
probably benign |
Het |
| Helz2 |
T |
C |
2: 180,882,362 (GRCm39) |
R144G |
probably benign |
Het |
| Herc1 |
A |
T |
9: 66,377,608 (GRCm39) |
K3458M |
possibly damaging |
Het |
| Hnf4g |
G |
T |
3: 3,709,647 (GRCm39) |
A144S |
probably damaging |
Het |
| Irs2 |
A |
C |
8: 11,037,012 (GRCm39) |
*1322G |
probably null |
Het |
| Keg1 |
A |
G |
19: 12,696,521 (GRCm39) |
N288S |
probably damaging |
Het |
| Kif19a |
G |
A |
11: 114,658,053 (GRCm39) |
M37I |
probably benign |
Het |
| Klhl1 |
G |
A |
14: 96,374,142 (GRCm39) |
P635S |
probably benign |
Het |
| Klk14 |
G |
A |
7: 43,341,501 (GRCm39) |
C51Y |
probably damaging |
Het |
| Lsm11 |
T |
C |
11: 45,835,666 (GRCm39) |
D25G |
probably damaging |
Het |
| Manea |
A |
T |
4: 26,336,630 (GRCm39) |
Y215* |
probably null |
Het |
| Mthfd1 |
T |
G |
12: 76,341,148 (GRCm39) |
V480G |
probably damaging |
Het |
| Mthfd1 |
T |
A |
12: 76,348,102 (GRCm39) |
M582K |
probably damaging |
Het |
| Myh7b |
G |
C |
2: 155,474,293 (GRCm39) |
R1669S |
possibly damaging |
Het |
| Nanos1 |
T |
C |
19: 60,745,418 (GRCm39) |
Y239H |
probably damaging |
Het |
| Nat8 |
G |
A |
6: 85,807,839 (GRCm39) |
T98I |
possibly damaging |
Het |
| Ndufs3 |
C |
A |
2: 90,729,004 (GRCm39) |
A161S |
probably benign |
Het |
| Nexmif |
A |
T |
X: 103,130,956 (GRCm39) |
N320K |
probably damaging |
Het |
| Or10h1 |
T |
C |
17: 33,418,751 (GRCm39) |
F239S |
probably damaging |
Het |
| Or2m12 |
A |
T |
16: 19,104,809 (GRCm39) |
V228D |
probably damaging |
Het |
| Or2r3 |
A |
T |
6: 42,448,221 (GRCm39) |
V297E |
possibly damaging |
Het |
| Or4c111 |
A |
G |
2: 88,844,387 (GRCm39) |
V7A |
probably damaging |
Het |
| Or4c122 |
C |
T |
2: 89,079,761 (GRCm39) |
M92I |
probably benign |
Het |
| Or4k15 |
T |
C |
14: 50,364,469 (GRCm39) |
V145A |
possibly damaging |
Het |
| Or52e2 |
G |
A |
7: 102,804,942 (GRCm39) |
P4L |
probably benign |
Het |
| Or6c69c |
T |
C |
10: 129,910,462 (GRCm39) |
L61P |
probably damaging |
Het |
| Pcdhb14 |
T |
A |
18: 37,583,223 (GRCm39) |
N776K |
probably benign |
Het |
| Pip5k1c |
G |
A |
10: 81,146,723 (GRCm39) |
|
probably null |
Het |
| Plk4 |
G |
A |
3: 40,756,512 (GRCm39) |
|
probably null |
Het |
| Prmt8 |
A |
G |
6: 127,688,126 (GRCm39) |
Y231H |
possibly damaging |
Het |
| Prpf4b |
T |
C |
13: 35,067,582 (GRCm39) |
|
probably benign |
Het |
| Ptpn21 |
G |
A |
12: 98,645,666 (GRCm39) |
R1091C |
probably damaging |
Het |
| Pwwp2b |
C |
T |
7: 138,835,494 (GRCm39) |
P312S |
possibly damaging |
Het |
| Rad21 |
A |
T |
15: 51,830,102 (GRCm39) |
I503K |
probably benign |
Het |
| Rai14 |
A |
G |
15: 10,574,592 (GRCm39) |
S789P |
probably damaging |
Het |
| Rbm26 |
C |
T |
14: 105,381,688 (GRCm39) |
D486N |
probably damaging |
Het |
| Rnf20 |
A |
G |
4: 49,642,016 (GRCm39) |
|
probably benign |
Het |
| Ros1 |
A |
G |
10: 52,000,171 (GRCm39) |
V1118A |
possibly damaging |
Het |
| Sema3d |
A |
C |
5: 12,634,923 (GRCm39) |
Y663S |
probably damaging |
Het |
| Serpina6 |
A |
G |
12: 103,617,971 (GRCm39) |
W281R |
probably damaging |
Het |
| Slc8a3 |
A |
G |
12: 81,246,332 (GRCm39) |
V900A |
probably damaging |
Het |
| Spats2l |
G |
T |
1: 57,918,715 (GRCm39) |
V30L |
probably damaging |
Het |
| Spg21 |
A |
G |
9: 65,383,231 (GRCm39) |
D139G |
probably damaging |
Het |
| Sun3 |
T |
C |
11: 8,988,314 (GRCm39) |
T3A |
probably damaging |
Het |
| Tep1 |
A |
G |
14: 51,066,456 (GRCm39) |
Y2335H |
probably benign |
Het |
| Tesl1 |
G |
A |
X: 23,773,480 (GRCm39) |
G327E |
probably damaging |
Het |
| Timd5 |
T |
A |
11: 46,419,359 (GRCm39) |
D58E |
probably damaging |
Het |
| Timm21 |
C |
A |
18: 84,967,539 (GRCm39) |
V112L |
possibly damaging |
Het |
| Tlk1 |
A |
T |
2: 70,572,409 (GRCm39) |
N386K |
probably benign |
Het |
| Trappc10 |
G |
T |
10: 78,052,994 (GRCm39) |
F260L |
possibly damaging |
Het |
| Trgv1 |
T |
A |
13: 19,524,401 (GRCm39) |
S42T |
probably benign |
Het |
| Trmt112 |
T |
C |
19: 6,888,121 (GRCm39) |
V91A |
probably benign |
Het |
| Ucp2 |
A |
T |
7: 100,147,579 (GRCm39) |
N186I |
possibly damaging |
Het |
| Vmn1r119 |
A |
G |
7: 20,746,245 (GRCm39) |
S46P |
probably benign |
Het |
| Vmn2r101 |
A |
T |
17: 19,831,649 (GRCm39) |
|
probably null |
Het |
| Vmn2r105 |
T |
A |
17: 20,428,676 (GRCm39) |
H800L |
probably damaging |
Het |
| Vmn2r69 |
T |
C |
7: 85,060,367 (GRCm39) |
M406V |
possibly damaging |
Het |
| Vmn2r84 |
A |
G |
10: 130,222,417 (GRCm39) |
L601P |
probably damaging |
Het |
| Vps16 |
A |
G |
2: 130,281,372 (GRCm39) |
S235G |
probably benign |
Het |
| Wap |
T |
C |
11: 6,587,339 (GRCm39) |
|
probably benign |
Het |
| Wdr11 |
A |
G |
7: 129,226,435 (GRCm39) |
I744M |
probably benign |
Het |
| Xiap |
T |
C |
X: 41,183,342 (GRCm39) |
F23L |
probably benign |
Het |
| Xkr7 |
A |
G |
2: 152,896,300 (GRCm39) |
T385A |
probably benign |
Het |
| Zfp524 |
A |
T |
7: 5,021,416 (GRCm39) |
I315F |
probably benign |
Het |
| Zfp62 |
T |
A |
11: 49,106,556 (GRCm39) |
S216T |
probably damaging |
Het |
| Znfx1 |
T |
C |
2: 166,881,746 (GRCm39) |
Y217C |
probably damaging |
Het |
|
| Other mutations in Mdga2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01343:Mdga2
|
APN |
12 |
66,769,883 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01632:Mdga2
|
APN |
12 |
66,676,672 (GRCm39) |
splice site |
probably benign |
|
|
IGL01843:Mdga2
|
APN |
12 |
66,769,905 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL02230:Mdga2
|
APN |
12 |
66,702,197 (GRCm39) |
nonsense |
probably null |
|
|
IGL02348:Mdga2
|
APN |
12 |
66,597,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02473:Mdga2
|
APN |
12 |
66,597,385 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL02795:Mdga2
|
APN |
12 |
66,736,206 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02901:Mdga2
|
APN |
12 |
66,844,583 (GRCm39) |
splice site |
probably benign |
|
|
IGL03373:Mdga2
|
APN |
12 |
66,763,496 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4362001:Mdga2
|
UTSW |
12 |
66,844,542 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
PIT4377001:Mdga2
|
UTSW |
12 |
66,763,469 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0106:Mdga2
|
UTSW |
12 |
66,763,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0106:Mdga2
|
UTSW |
12 |
66,763,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0110:Mdga2
|
UTSW |
12 |
66,517,700 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R0218:Mdga2
|
UTSW |
12 |
66,701,894 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0450:Mdga2
|
UTSW |
12 |
66,517,700 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R0801:Mdga2
|
UTSW |
12 |
66,533,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0847:Mdga2
|
UTSW |
12 |
66,769,854 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1056:Mdga2
|
UTSW |
12 |
66,769,894 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1086:Mdga2
|
UTSW |
12 |
66,552,876 (GRCm39) |
splice site |
probably benign |
|
|
R1335:Mdga2
|
UTSW |
12 |
66,763,516 (GRCm39) |
splice site |
probably null |
|
|
R1382:Mdga2
|
UTSW |
12 |
66,517,690 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1490:Mdga2
|
UTSW |
12 |
66,844,530 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1521:Mdga2
|
UTSW |
12 |
66,615,700 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1556:Mdga2
|
UTSW |
12 |
66,597,367 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1676:Mdga2
|
UTSW |
12 |
66,615,547 (GRCm39) |
nonsense |
probably null |
|
|
R1676:Mdga2
|
UTSW |
12 |
66,615,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1698:Mdga2
|
UTSW |
12 |
66,736,109 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1954:Mdga2
|
UTSW |
12 |
66,533,482 (GRCm39) |
splice site |
probably benign |
|
|
R2069:Mdga2
|
UTSW |
12 |
66,615,691 (GRCm39) |
nonsense |
probably null |
|
|
R2077:Mdga2
|
UTSW |
12 |
66,702,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2118:Mdga2
|
UTSW |
12 |
66,915,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2146:Mdga2
|
UTSW |
12 |
66,915,515 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2158:Mdga2
|
UTSW |
12 |
66,736,155 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R2189:Mdga2
|
UTSW |
12 |
66,519,970 (GRCm39) |
splice site |
probably null |
|
|
R2293:Mdga2
|
UTSW |
12 |
66,615,759 (GRCm39) |
nonsense |
probably null |
|
|
R2886:Mdga2
|
UTSW |
12 |
66,553,044 (GRCm39) |
splice site |
probably benign |
|
|
R2960:Mdga2
|
UTSW |
12 |
66,676,752 (GRCm39) |
nonsense |
probably null |
|
|
R3937:Mdga2
|
UTSW |
12 |
67,267,980 (GRCm39) |
unclassified |
probably benign |
|
|
R4437:Mdga2
|
UTSW |
12 |
66,519,972 (GRCm39) |
splice site |
probably null |
|
|
R4514:Mdga2
|
UTSW |
12 |
66,763,496 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4693:Mdga2
|
UTSW |
12 |
66,844,407 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4719:Mdga2
|
UTSW |
12 |
66,517,775 (GRCm39) |
unclassified |
probably benign |
|
|
R4744:Mdga2
|
UTSW |
12 |
66,844,501 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4756:Mdga2
|
UTSW |
12 |
66,844,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4781:Mdga2
|
UTSW |
12 |
66,844,396 (GRCm39) |
splice site |
probably null |
|
|
R5108:Mdga2
|
UTSW |
12 |
66,533,515 (GRCm39) |
missense |
probably benign |
0.43 |
|
R5479:Mdga2
|
UTSW |
12 |
66,701,950 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5710:Mdga2
|
UTSW |
12 |
66,553,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5816:Mdga2
|
UTSW |
12 |
66,701,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5822:Mdga2
|
UTSW |
12 |
66,702,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5996:Mdga2
|
UTSW |
12 |
66,844,537 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6038:Mdga2
|
UTSW |
12 |
66,676,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6038:Mdga2
|
UTSW |
12 |
66,676,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6297:Mdga2
|
UTSW |
12 |
66,553,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6484:Mdga2
|
UTSW |
12 |
66,676,843 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6830:Mdga2
|
UTSW |
12 |
66,769,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6912:Mdga2
|
UTSW |
12 |
66,552,889 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6971:Mdga2
|
UTSW |
12 |
66,597,335 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7053:Mdga2
|
UTSW |
12 |
66,736,158 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7069:Mdga2
|
UTSW |
12 |
66,533,526 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7381:Mdga2
|
UTSW |
12 |
66,615,670 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7474:Mdga2
|
UTSW |
12 |
66,533,535 (GRCm39) |
nonsense |
probably null |
|
|
R7559:Mdga2
|
UTSW |
12 |
66,520,003 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7581:Mdga2
|
UTSW |
12 |
66,553,029 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7596:Mdga2
|
UTSW |
12 |
66,552,897 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7745:Mdga2
|
UTSW |
12 |
66,736,125 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R7745:Mdga2
|
UTSW |
12 |
66,736,124 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7852:Mdga2
|
UTSW |
12 |
66,517,724 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R8144:Mdga2
|
UTSW |
12 |
66,702,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8319:Mdga2
|
UTSW |
12 |
67,267,803 (GRCm39) |
missense |
unknown |
|
|
R8715:Mdga2
|
UTSW |
12 |
66,915,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8977:Mdga2
|
UTSW |
12 |
66,844,409 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9138:Mdga2
|
UTSW |
12 |
66,615,663 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9177:Mdga2
|
UTSW |
12 |
66,517,481 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9223:Mdga2
|
UTSW |
12 |
66,615,634 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9248:Mdga2
|
UTSW |
12 |
66,736,226 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9264:Mdga2
|
UTSW |
12 |
66,560,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9381:Mdga2
|
UTSW |
12 |
66,597,304 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R9456:Mdga2
|
UTSW |
12 |
66,615,532 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9633:Mdga2
|
UTSW |
12 |
66,736,206 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Mdga2
|
UTSW |
12 |
66,736,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1186:Mdga2
|
UTSW |
12 |
66,615,727 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGGCTTGTTTCATTGAAGGCAC -3'
(R):5'- GGCTGTTACCCTTCCTTGAAAATAC -3'
Sequencing Primer
(F):5'- AGGCACTTGGTTTCCATGGC -3'
(R):5'- TTCCTTGAAAATACTCCAAACTCGG -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation