Incidental Mutation 'R7447:Ly75'
| ID |
577335 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ly75
|
| Ensembl Gene |
ENSMUSG00000026980 |
| Gene Name |
lymphocyte antigen 75 |
| Synonyms |
DEC-205, CD205 |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7447 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
60122447-60213617 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
C to A
at 60164818 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Stop codon
at position 787
(E787*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000028362
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028362]
[ENSMUST00000112533]
|
| AlphaFold |
Q60767 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000028362
AA Change: E787*
|
| SMART Domains |
Protein: ENSMUSP00000028362
Gene: ENSMUSG00000026980
AA Change: E787*
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000112533
AA Change: E787*
|
| SMART Domains |
Protein: ENSMUSP00000108152
Gene: ENSMUSG00000026980
AA Change: E787*
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele display abnormalities in CD8-positive T cell morphology and cytotoxic T cell physiology. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(7) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(5)
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adck5 |
A |
T |
15: 76,479,396 (GRCm39) |
I484F |
possibly damaging |
Het |
| Ago2 |
A |
T |
15: 73,009,881 (GRCm39) |
N100K |
probably benign |
Het |
| Appl1 |
T |
A |
14: 26,681,409 (GRCm39) |
K130* |
probably null |
Het |
| Arhgap39 |
G |
A |
15: 76,649,797 (GRCm39) |
|
probably benign |
Het |
| Axdnd1 |
A |
G |
1: 156,245,802 (GRCm39) |
|
probably null |
Het |
| Camta1 |
A |
T |
4: 151,168,327 (GRCm39) |
V1332E |
probably benign |
Het |
| Cd3g |
A |
G |
9: 44,884,857 (GRCm39) |
L129P |
probably damaging |
Het |
| Cd80 |
T |
G |
16: 38,294,251 (GRCm39) |
S45A |
probably benign |
Het |
| Cdk12 |
A |
T |
11: 98,136,106 (GRCm39) |
Q1120L |
unknown |
Het |
| Clip1 |
G |
A |
5: 123,791,696 (GRCm39) |
S158F |
probably benign |
Het |
| Cntn3 |
C |
A |
6: 102,255,416 (GRCm39) |
E161* |
probably null |
Het |
| Cyp3a59 |
A |
C |
5: 146,024,215 (GRCm39) |
K67T |
probably benign |
Het |
| Dmxl1 |
T |
C |
18: 49,997,681 (GRCm39) |
L623P |
probably damaging |
Het |
| Drd3 |
T |
A |
16: 43,637,426 (GRCm39) |
Y208* |
probably null |
Het |
| Dusp10 |
A |
T |
1: 183,801,153 (GRCm39) |
M307L |
probably benign |
Het |
| Dync2li1 |
A |
T |
17: 84,955,141 (GRCm39) |
I267L |
possibly damaging |
Het |
| Dynlt2b |
T |
A |
16: 32,244,089 (GRCm39) |
V95E |
probably damaging |
Het |
| Edn3 |
C |
A |
2: 174,603,544 (GRCm39) |
C97* |
probably null |
Het |
| Ehbp1l1 |
T |
A |
19: 5,769,456 (GRCm39) |
T616S |
possibly damaging |
Het |
| Eif2a |
C |
T |
3: 58,452,963 (GRCm39) |
T246I |
probably damaging |
Het |
| Enpp5 |
G |
A |
17: 44,396,155 (GRCm39) |
G356S |
probably damaging |
Het |
| Errfi1 |
A |
G |
4: 150,951,108 (GRCm39) |
T179A |
probably damaging |
Het |
| Esyt3 |
G |
A |
9: 99,203,615 (GRCm39) |
L450F |
probably damaging |
Het |
| Evx2 |
A |
G |
2: 74,489,448 (GRCm39) |
S106P |
probably benign |
Het |
| Fam83a |
T |
G |
15: 57,873,086 (GRCm39) |
V305G |
probably benign |
Het |
| Fem1al |
T |
C |
11: 29,774,122 (GRCm39) |
D445G |
probably benign |
Het |
| Gpr171 |
T |
A |
3: 59,005,860 (GRCm39) |
|
probably null |
Het |
| Grip1 |
A |
G |
10: 119,922,871 (GRCm39) |
T1106A |
probably benign |
Het |
| Hecw1 |
A |
G |
13: 14,531,789 (GRCm39) |
Y162H |
probably damaging |
Het |
| Hephl1 |
C |
T |
9: 15,009,178 (GRCm39) |
|
probably null |
Het |
| Hsp90aa1 |
A |
G |
12: 110,658,562 (GRCm39) |
I693T |
possibly damaging |
Het |
| Ifit1bl2 |
T |
A |
19: 34,596,974 (GRCm39) |
D214V |
probably damaging |
Het |
| Igsf10 |
T |
C |
3: 59,239,222 (GRCm39) |
M320V |
probably benign |
Het |
| Kcnq2 |
A |
G |
2: 180,754,887 (GRCm39) |
L220P |
probably damaging |
Het |
| Kpna1 |
C |
A |
16: 35,850,009 (GRCm39) |
Q372K |
probably damaging |
Het |
| Lilrb4a |
T |
G |
10: 51,367,149 (GRCm39) |
|
probably null |
Het |
| Magi1 |
T |
G |
6: 93,722,562 (GRCm39) |
S666R |
possibly damaging |
Het |
| Mif |
C |
A |
10: 75,695,687 (GRCm39) |
A39S |
possibly damaging |
Het |
| Mob4 |
G |
A |
1: 55,170,625 (GRCm39) |
|
probably benign |
Het |
| Mtmr4 |
G |
T |
11: 87,502,727 (GRCm39) |
C927F |
probably damaging |
Het |
| Myh1 |
A |
G |
11: 67,110,006 (GRCm39) |
K1398R |
probably benign |
Het |
| Myo3a |
T |
C |
2: 22,436,464 (GRCm39) |
V873A |
probably benign |
Het |
| Naip5 |
T |
C |
13: 100,356,204 (GRCm39) |
Q1137R |
probably benign |
Het |
| Naip5 |
G |
T |
13: 100,356,205 (GRCm39) |
Q1137K |
not run |
Het |
| Nckap5l |
G |
A |
15: 99,325,357 (GRCm39) |
P382L |
probably damaging |
Het |
| Ngly1 |
T |
C |
14: 16,290,844 (GRCm38) |
I442T |
probably damaging |
Het |
| Nhsl3 |
C |
A |
4: 129,115,835 (GRCm39) |
R988L |
possibly damaging |
Het |
| Nlrp1a |
T |
C |
11: 70,983,237 (GRCm39) |
Y1243C |
probably damaging |
Het |
| Or8k53 |
T |
A |
2: 86,177,150 (GRCm39) |
H320L |
possibly damaging |
Het |
| Pcsk5 |
C |
T |
19: 17,487,600 (GRCm39) |
G1027D |
probably benign |
Het |
| Pla2g2c |
T |
A |
4: 138,458,927 (GRCm39) |
I11N |
probably benign |
Het |
| Polr3d |
A |
G |
14: 70,677,240 (GRCm39) |
I331T |
probably damaging |
Het |
| Ppp4r4 |
A |
G |
12: 103,551,985 (GRCm39) |
I293M |
possibly damaging |
Het |
| Prkce |
G |
T |
17: 86,866,687 (GRCm39) |
V516F |
probably damaging |
Het |
| Prss27 |
T |
A |
17: 24,264,683 (GRCm39) |
L282Q |
probably damaging |
Het |
| Pxdn |
A |
G |
12: 30,034,926 (GRCm39) |
Y261C |
probably damaging |
Het |
| R3hcc1l |
T |
C |
19: 42,551,101 (GRCm39) |
S33P |
probably benign |
Het |
| Rab11fip3 |
G |
C |
17: 26,287,848 (GRCm39) |
R102G |
possibly damaging |
Het |
| Rabggta |
A |
T |
14: 55,956,773 (GRCm39) |
N310K |
probably null |
Het |
| Rbbp8 |
T |
A |
18: 11,793,934 (GRCm39) |
D15E |
probably benign |
Het |
| Rbm5 |
T |
C |
9: 107,623,378 (GRCm39) |
Y486C |
probably damaging |
Het |
| Rptor |
T |
A |
11: 119,775,805 (GRCm39) |
F992Y |
probably benign |
Het |
| Slc29a2 |
T |
G |
19: 5,076,445 (GRCm39) |
L111R |
probably damaging |
Het |
| Slc39a11 |
T |
A |
11: 113,452,849 (GRCm39) |
I31L |
probably benign |
Het |
| Slc6a20a |
T |
A |
9: 123,485,289 (GRCm39) |
N311I |
possibly damaging |
Het |
| Slc8a1 |
A |
G |
17: 81,956,435 (GRCm39) |
F201S |
probably damaging |
Het |
| Smtn |
C |
A |
11: 3,480,196 (GRCm39) |
V342L |
probably benign |
Het |
| Syne2 |
A |
G |
12: 76,074,853 (GRCm39) |
T4598A |
probably benign |
Het |
| Tchp |
A |
G |
5: 114,853,716 (GRCm39) |
T267A |
probably benign |
Het |
| Tes3-ps |
A |
G |
13: 49,647,508 (GRCm39) |
E128G |
possibly damaging |
Het |
| Tigar |
C |
T |
6: 127,065,129 (GRCm39) |
G173E |
probably benign |
Het |
| Tmem171 |
T |
C |
13: 98,824,862 (GRCm39) |
N256S |
probably benign |
Het |
| Tmem204 |
A |
G |
17: 25,277,270 (GRCm39) |
I205T |
probably damaging |
Het |
| Tmem63a |
A |
G |
1: 180,785,588 (GRCm39) |
K240R |
probably benign |
Het |
| Tns2 |
C |
T |
15: 102,019,351 (GRCm39) |
T446M |
probably damaging |
Het |
| Tnxb |
A |
T |
17: 34,937,444 (GRCm39) |
N2931I |
probably damaging |
Het |
| Trrap |
G |
T |
5: 144,776,284 (GRCm39) |
R2941L |
probably damaging |
Het |
| Ttc8 |
A |
T |
12: 98,910,131 (GRCm39) |
R179S |
probably damaging |
Het |
| Ttll12 |
G |
T |
15: 83,471,176 (GRCm39) |
T234N |
probably damaging |
Het |
| Ttn |
G |
T |
2: 76,577,576 (GRCm39) |
T24439K |
probably damaging |
Het |
| Ube2z |
A |
T |
11: 95,946,736 (GRCm39) |
I246N |
possibly damaging |
Het |
| Usp15 |
A |
G |
10: 123,011,786 (GRCm39) |
Y104H |
probably damaging |
Het |
| Usp29 |
A |
C |
7: 6,964,219 (GRCm39) |
T21P |
possibly damaging |
Het |
| Usp5 |
G |
A |
6: 124,798,077 (GRCm39) |
A436V |
probably damaging |
Het |
| Utp20 |
A |
G |
10: 88,608,354 (GRCm39) |
L1561S |
probably damaging |
Het |
| Xrn1 |
A |
G |
9: 95,927,547 (GRCm39) |
M1444V |
probably benign |
Het |
| Zfp236 |
G |
T |
18: 82,651,815 (GRCm39) |
Q885K |
probably damaging |
Het |
| Zfp831 |
C |
A |
2: 174,487,896 (GRCm39) |
P857Q |
possibly damaging |
Het |
|
| Other mutations in Ly75 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00561:Ly75
|
APN |
2 |
60,206,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01072:Ly75
|
APN |
2 |
60,184,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01409:Ly75
|
APN |
2 |
60,152,036 (GRCm39) |
splice site |
probably null |
|
|
IGL01432:Ly75
|
APN |
2 |
60,206,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01626:Ly75
|
APN |
2 |
60,131,359 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL01690:Ly75
|
APN |
2 |
60,168,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01862:Ly75
|
APN |
2 |
60,129,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01982:Ly75
|
APN |
2 |
60,142,108 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02075:Ly75
|
APN |
2 |
60,182,700 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02338:Ly75
|
APN |
2 |
60,184,796 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02364:Ly75
|
APN |
2 |
60,188,851 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02456:Ly75
|
APN |
2 |
60,124,125 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02474:Ly75
|
APN |
2 |
60,213,526 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL02608:Ly75
|
APN |
2 |
60,152,244 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL02986:Ly75
|
APN |
2 |
60,138,535 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03015:Ly75
|
APN |
2 |
60,206,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03049:Ly75
|
APN |
2 |
60,182,414 (GRCm39) |
missense |
probably damaging |
0.99 |
|
euphues
|
UTSW |
2 |
60,129,389 (GRCm39) |
critical splice donor site |
probably null |
|
|
four_score
|
UTSW |
2 |
60,142,115 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
lyly
|
UTSW |
2 |
60,158,217 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
Witty
|
UTSW |
2 |
60,184,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
D605:Ly75
|
UTSW |
2 |
60,182,696 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0046:Ly75
|
UTSW |
2 |
60,169,801 (GRCm39) |
intron |
probably benign |
|
|
R0055:Ly75
|
UTSW |
2 |
60,152,262 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0055:Ly75
|
UTSW |
2 |
60,152,262 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,152,163 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,152,163 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0285:Ly75
|
UTSW |
2 |
60,148,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0387:Ly75
|
UTSW |
2 |
60,136,748 (GRCm39) |
missense |
probably benign |
0.20 |
|
R0492:Ly75
|
UTSW |
2 |
60,138,620 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0688:Ly75
|
UTSW |
2 |
60,146,565 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1367:Ly75
|
UTSW |
2 |
60,124,102 (GRCm39) |
splice site |
probably null |
|
|
R1463:Ly75
|
UTSW |
2 |
60,199,101 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1581:Ly75
|
UTSW |
2 |
60,158,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1663:Ly75
|
UTSW |
2 |
60,144,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1818:Ly75
|
UTSW |
2 |
60,142,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1881:Ly75
|
UTSW |
2 |
60,180,284 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2244:Ly75
|
UTSW |
2 |
60,180,257 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2905:Ly75
|
UTSW |
2 |
60,164,898 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3967:Ly75
|
UTSW |
2 |
60,158,217 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R3968:Ly75
|
UTSW |
2 |
60,158,217 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4039:Ly75
|
UTSW |
2 |
60,183,339 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4406:Ly75
|
UTSW |
2 |
60,184,894 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4526:Ly75
|
UTSW |
2 |
60,161,117 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4647:Ly75
|
UTSW |
2 |
60,138,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4795:Ly75
|
UTSW |
2 |
60,180,284 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4796:Ly75
|
UTSW |
2 |
60,180,284 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4962:Ly75
|
UTSW |
2 |
60,182,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4979:Ly75
|
UTSW |
2 |
60,206,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5072:Ly75
|
UTSW |
2 |
60,206,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5288:Ly75
|
UTSW |
2 |
60,133,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5373:Ly75
|
UTSW |
2 |
60,142,115 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5374:Ly75
|
UTSW |
2 |
60,142,115 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5384:Ly75
|
UTSW |
2 |
60,164,831 (GRCm39) |
nonsense |
probably null |
|
|
R5385:Ly75
|
UTSW |
2 |
60,133,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5395:Ly75
|
UTSW |
2 |
60,195,455 (GRCm39) |
missense |
probably benign |
0.41 |
|
R5531:Ly75
|
UTSW |
2 |
60,195,489 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5662:Ly75
|
UTSW |
2 |
60,182,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5667:Ly75
|
UTSW |
2 |
60,138,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5668:Ly75
|
UTSW |
2 |
60,184,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5671:Ly75
|
UTSW |
2 |
60,138,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5677:Ly75
|
UTSW |
2 |
60,129,426 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5764:Ly75
|
UTSW |
2 |
60,148,783 (GRCm39) |
missense |
probably benign |
|
|
R5896:Ly75
|
UTSW |
2 |
60,213,490 (GRCm39) |
missense |
probably benign |
|
|
R6025:Ly75
|
UTSW |
2 |
60,206,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6113:Ly75
|
UTSW |
2 |
60,199,217 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6448:Ly75
|
UTSW |
2 |
60,129,389 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6601:Ly75
|
UTSW |
2 |
60,148,720 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6745:Ly75
|
UTSW |
2 |
60,138,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6955:Ly75
|
UTSW |
2 |
60,158,217 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R6960:Ly75
|
UTSW |
2 |
60,136,749 (GRCm39) |
missense |
probably benign |
|
|
R7100:Ly75
|
UTSW |
2 |
60,136,778 (GRCm39) |
missense |
probably benign |
|
|
R7110:Ly75
|
UTSW |
2 |
60,206,528 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7203:Ly75
|
UTSW |
2 |
60,154,196 (GRCm39) |
nonsense |
probably null |
|
|
R7291:Ly75
|
UTSW |
2 |
60,160,337 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7308:Ly75
|
UTSW |
2 |
60,164,859 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7512:Ly75
|
UTSW |
2 |
60,164,907 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7595:Ly75
|
UTSW |
2 |
60,124,171 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7976:Ly75
|
UTSW |
2 |
60,195,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8005:Ly75
|
UTSW |
2 |
60,163,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Ly75
|
UTSW |
2 |
60,144,572 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8392:Ly75
|
UTSW |
2 |
60,180,284 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8705:Ly75
|
UTSW |
2 |
60,148,729 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8714:Ly75
|
UTSW |
2 |
60,164,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8798:Ly75
|
UTSW |
2 |
60,154,270 (GRCm39) |
missense |
probably benign |
0.32 |
|
R8799:Ly75
|
UTSW |
2 |
60,178,785 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8834:Ly75
|
UTSW |
2 |
60,161,433 (GRCm39) |
missense |
probably benign |
|
|
R8990:Ly75
|
UTSW |
2 |
60,188,903 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9015:Ly75
|
UTSW |
2 |
60,146,442 (GRCm39) |
missense |
probably benign |
|
|
R9547:Ly75
|
UTSW |
2 |
60,161,069 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9628:Ly75
|
UTSW |
2 |
60,158,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9659:Ly75
|
UTSW |
2 |
60,168,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9660:Ly75
|
UTSW |
2 |
60,154,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9747:Ly75
|
UTSW |
2 |
60,136,672 (GRCm39) |
critical splice donor site |
probably null |
|
|
X0025:Ly75
|
UTSW |
2 |
60,184,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Ly75
|
UTSW |
2 |
60,182,477 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
Z1177:Ly75
|
UTSW |
2 |
60,180,348 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGTCATTGCAGGTTCTACTGTC -3'
(R):5'- TGCTGAGTTACTGTTCAATGTCC -3'
Sequencing Primer
(F):5'- AACTGGTTTCTTGAATTCGAATTTAC -3'
(R):5'- CCCATTTCTTCATAAGTATGGTAGG -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation