Incidental Mutation 'R1835:Patj'
| ID |
205146 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Patj
|
| Ensembl Gene |
ENSMUSG00000061859 |
| Gene Name |
PATJ, crumbs cell polarity complex component |
| Synonyms |
Cipp, Inadl |
| MMRRC Submission |
039862-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1835 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
98284022-98607840 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 98379827 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 151
(D151G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000102644
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041284]
[ENSMUST00000107029]
[ENSMUST00000107033]
[ENSMUST00000107034]
|
| AlphaFold |
Q63ZW7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041284
AA Change: D724G
PolyPhen 2
Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)
|
| SMART Domains |
Protein: ENSMUSP00000049176
Gene: ENSMUSG00000061859
AA Change: D724G
| Domain | Start | End | E-Value | Type |
|---|
|
L27
|
8 |
68 |
6.53e-9 |
SMART |
|
PDZ
|
143 |
221 |
1.78e-20 |
SMART |
|
PDZ
|
256 |
328 |
1.15e-23 |
SMART |
|
PDZ
|
374 |
453 |
3.15e-21 |
SMART |
|
coiled coil region
|
486 |
513 |
N/A |
INTRINSIC |
|
PDZ
|
570 |
641 |
1.28e-12 |
SMART |
|
PDZ
|
696 |
775 |
9.5e-16 |
SMART |
|
low complexity region
|
980 |
991 |
N/A |
INTRINSIC |
|
low complexity region
|
1054 |
1062 |
N/A |
INTRINSIC |
|
PDZ
|
1083 |
1166 |
8.65e-19 |
SMART |
|
PDZ
|
1253 |
1328 |
6.12e-19 |
SMART |
|
low complexity region
|
1356 |
1366 |
N/A |
INTRINSIC |
|
low complexity region
|
1410 |
1428 |
N/A |
INTRINSIC |
|
PDZ
|
1480 |
1555 |
4.36e-24 |
SMART |
|
PDZ
|
1577 |
1650 |
2.49e-19 |
SMART |
|
PDZ
|
1718 |
1795 |
2.13e-18 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000107029
AA Change: D151G
PolyPhen 2
Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)
|
| SMART Domains |
Protein: ENSMUSP00000102644
Gene: ENSMUSG00000061859
AA Change: D151G
| Domain | Start | End | E-Value | Type |
|---|
|
PDZ
|
1 |
68 |
1e-9 |
SMART |
|
PDZ
|
123 |
202 |
4.7e-18 |
SMART |
|
low complexity region
|
407 |
418 |
N/A |
INTRINSIC |
|
low complexity region
|
481 |
489 |
N/A |
INTRINSIC |
|
PDZ
|
510 |
593 |
4.3e-21 |
SMART |
|
PDZ
|
680 |
755 |
2.9e-21 |
SMART |
|
low complexity region
|
783 |
793 |
N/A |
INTRINSIC |
|
low complexity region
|
837 |
855 |
N/A |
INTRINSIC |
|
PDZ
|
907 |
982 |
2.2e-26 |
SMART |
|
PDZ
|
1004 |
1077 |
1.2e-21 |
SMART |
|
PDZ
|
1145 |
1222 |
1e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000107033
|
| SMART Domains |
Protein: ENSMUSP00000102648
Gene: ENSMUSG00000061859
| Domain | Start | End | E-Value | Type |
|---|
|
L27
|
8 |
68 |
6.53e-9 |
SMART |
|
PDZ
|
143 |
221 |
1.78e-20 |
SMART |
|
PDZ
|
256 |
328 |
1.15e-23 |
SMART |
|
PDZ
|
374 |
453 |
3.15e-21 |
SMART |
|
coiled coil region
|
486 |
513 |
N/A |
INTRINSIC |
|
low complexity region
|
648 |
659 |
N/A |
INTRINSIC |
|
low complexity region
|
722 |
730 |
N/A |
INTRINSIC |
|
PDZ
|
751 |
834 |
8.65e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000107034
AA Change: D720G
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000102649
Gene: ENSMUSG00000061859
AA Change: D720G
| Domain | Start | End | E-Value | Type |
|---|
|
L27
|
8 |
68 |
6.53e-9 |
SMART |
|
PDZ
|
143 |
221 |
1.78e-20 |
SMART |
|
PDZ
|
256 |
328 |
1.15e-23 |
SMART |
|
PDZ
|
374 |
453 |
3.15e-21 |
SMART |
|
coiled coil region
|
486 |
513 |
N/A |
INTRINSIC |
|
PDZ
|
566 |
637 |
1.28e-12 |
SMART |
|
PDZ
|
692 |
771 |
9.5e-16 |
SMART |
|
low complexity region
|
976 |
987 |
N/A |
INTRINSIC |
|
low complexity region
|
1050 |
1058 |
N/A |
INTRINSIC |
|
PDZ
|
1079 |
1162 |
8.65e-19 |
SMART |
|
PDZ
|
1249 |
1324 |
6.12e-19 |
SMART |
|
low complexity region
|
1352 |
1362 |
N/A |
INTRINSIC |
|
low complexity region
|
1382 |
1400 |
N/A |
INTRINSIC |
|
PDZ
|
1452 |
1499 |
7.78e0 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135606
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000142103
AA Change: D202G
|
| SMART Domains |
Protein: ENSMUSP00000116021
Gene: ENSMUSG00000061859
AA Change: D202G
| Domain | Start | End | E-Value | Type |
|---|
|
PDZ
|
49 |
120 |
1.28e-12 |
SMART |
|
PDZ
|
175 |
254 |
9.5e-16 |
SMART |
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 94.9%
- 20x: 91.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a multivalent PDZ domain protein, which is expressed exclusively in brain and kidney. This protein selectively interacts with inward rectifier K+ (Kir) family members, N-methyl-D-aspartate receptor subunits, neurexins and neuroligins, as well as cell surface molecules enriched in synaptic membranes. Thus, this protein may serve as a scaffold that brings structurally diverse but functionally connected proteins into close proximity at the synapse. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
All alleles(5) : Gene trapped(5) |
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acss2 |
T |
A |
2: 155,400,550 (GRCm39) |
Y530N |
probably damaging |
Het |
| Adam4 |
T |
C |
12: 81,466,333 (GRCm39) |
I763V |
probably benign |
Het |
| Aipl1 |
T |
G |
11: 71,921,325 (GRCm39) |
K190T |
possibly damaging |
Het |
| Alms1 |
T |
A |
6: 85,655,485 (GRCm39) |
S3344T |
possibly damaging |
Het |
| Alpi |
A |
G |
1: 87,027,136 (GRCm39) |
V381A |
possibly damaging |
Het |
| Ankfn1 |
A |
T |
11: 89,338,444 (GRCm39) |
S365R |
probably benign |
Het |
| Aox1 |
G |
A |
1: 58,348,150 (GRCm39) |
A623T |
probably benign |
Het |
| Apc |
T |
A |
18: 34,450,130 (GRCm39) |
L2308Q |
probably damaging |
Het |
| Atp9b |
C |
T |
18: 80,822,098 (GRCm39) |
V501I |
probably benign |
Het |
| Baz2b |
T |
C |
2: 59,732,163 (GRCm39) |
E1994G |
probably benign |
Het |
| Bltp2 |
G |
T |
11: 78,178,576 (GRCm39) |
V1993F |
probably damaging |
Het |
| Cacna1a |
T |
C |
8: 85,307,986 (GRCm39) |
|
probably null |
Het |
| Cacna1h |
C |
A |
17: 25,611,050 (GRCm39) |
V583L |
probably benign |
Het |
| Cd55 |
T |
C |
1: 130,375,346 (GRCm39) |
|
probably benign |
Het |
| Cep192 |
T |
A |
18: 67,937,494 (GRCm39) |
S75T |
possibly damaging |
Het |
| Cfap54 |
T |
A |
10: 92,798,237 (GRCm39) |
D1674V |
probably benign |
Het |
| Churc1 |
T |
C |
12: 76,820,071 (GRCm39) |
F27L |
possibly damaging |
Het |
| Coro1c |
A |
G |
5: 113,986,604 (GRCm39) |
I280T |
probably benign |
Het |
| Creb1 |
C |
T |
1: 64,590,109 (GRCm39) |
Q32* |
probably null |
Het |
| Cyp2b9 |
A |
G |
7: 25,900,208 (GRCm39) |
T339A |
probably benign |
Het |
| Dctn3 |
T |
C |
4: 41,720,813 (GRCm39) |
R51G |
probably damaging |
Het |
| Ddb1 |
T |
C |
19: 10,603,957 (GRCm39) |
V888A |
probably damaging |
Het |
| Disp1 |
A |
G |
1: 182,870,564 (GRCm39) |
Y619H |
probably damaging |
Het |
| Dnajc9 |
T |
C |
14: 20,438,402 (GRCm39) |
D96G |
possibly damaging |
Het |
| Eepd1 |
A |
G |
9: 25,394,164 (GRCm39) |
T143A |
possibly damaging |
Het |
| Eps8 |
T |
A |
6: 137,499,277 (GRCm39) |
K204* |
probably null |
Het |
| Ercc5 |
T |
A |
1: 44,220,035 (GRCm39) |
S1102R |
probably benign |
Het |
| Ergic2 |
T |
A |
6: 148,091,079 (GRCm39) |
Y211F |
possibly damaging |
Het |
| Fam135b |
G |
T |
15: 71,362,560 (GRCm39) |
L274M |
probably damaging |
Het |
| Fat3 |
G |
A |
9: 15,909,384 (GRCm39) |
T2206I |
probably damaging |
Het |
| Fat4 |
A |
G |
3: 39,037,720 (GRCm39) |
I3791V |
probably benign |
Het |
| Gemin4 |
A |
G |
11: 76,104,122 (GRCm39) |
M213T |
possibly damaging |
Het |
| Gnai3 |
T |
C |
3: 108,025,723 (GRCm39) |
M119V |
probably benign |
Het |
| Heatr5b |
A |
T |
17: 79,080,992 (GRCm39) |
L1420Q |
probably damaging |
Het |
| Herc2 |
G |
T |
7: 55,856,513 (GRCm39) |
G3918* |
probably null |
Het |
| Ints9 |
A |
G |
14: 65,269,705 (GRCm39) |
Y465C |
probably damaging |
Het |
| Ist1 |
A |
G |
8: 110,405,515 (GRCm39) |
V175A |
probably damaging |
Het |
| Kcnj12 |
T |
C |
11: 60,960,383 (GRCm39) |
L227P |
possibly damaging |
Het |
| Kcnq5 |
T |
C |
1: 21,536,611 (GRCm39) |
S416G |
probably benign |
Het |
| Kdm3a |
T |
A |
6: 71,590,940 (GRCm39) |
T295S |
probably benign |
Het |
| Kif1c |
T |
A |
11: 70,599,797 (GRCm39) |
M479K |
probably damaging |
Het |
| Kif20b |
T |
C |
19: 34,933,438 (GRCm39) |
L83P |
probably damaging |
Het |
| Kndc1 |
A |
G |
7: 139,507,624 (GRCm39) |
E1194G |
probably damaging |
Het |
| Llgl1 |
A |
G |
11: 60,595,556 (GRCm39) |
M81V |
probably benign |
Het |
| Map4k5 |
C |
A |
12: 69,871,436 (GRCm39) |
M495I |
probably damaging |
Het |
| Mest |
C |
T |
6: 30,742,790 (GRCm39) |
R146C |
probably benign |
Het |
| Mettl24 |
T |
A |
10: 40,613,812 (GRCm39) |
|
probably null |
Het |
| Mical1 |
T |
C |
10: 41,359,531 (GRCm39) |
S586P |
probably benign |
Het |
| Mrgpra3 |
G |
T |
7: 47,239,694 (GRCm39) |
Y77* |
probably null |
Het |
| Mss51 |
A |
T |
14: 20,533,246 (GRCm39) |
C408* |
probably null |
Het |
| Myh6 |
T |
C |
14: 55,194,858 (GRCm39) |
T666A |
probably benign |
Het |
| Myo10 |
T |
C |
15: 25,805,673 (GRCm39) |
C1685R |
possibly damaging |
Het |
| Naip5 |
A |
T |
13: 100,359,726 (GRCm39) |
Y503* |
probably null |
Het |
| Neil1 |
A |
C |
9: 57,053,888 (GRCm39) |
F144C |
probably damaging |
Het |
| Nipbl |
T |
A |
15: 8,373,001 (GRCm39) |
I1082F |
possibly damaging |
Het |
| Nkiras1 |
T |
C |
14: 18,276,732 (GRCm38) |
V7A |
probably damaging |
Het |
| Nt5el |
C |
A |
13: 105,218,702 (GRCm39) |
A12E |
unknown |
Het |
| Ntng2 |
G |
A |
2: 29,087,069 (GRCm39) |
Q384* |
probably null |
Het |
| Ocrl |
T |
A |
X: 47,050,993 (GRCm39) |
I74N |
probably damaging |
Het |
| Or10j27 |
A |
G |
1: 172,958,382 (GRCm39) |
V134A |
probably benign |
Het |
| Or13a22 |
A |
G |
7: 140,072,622 (GRCm39) |
S24G |
probably benign |
Het |
| Or14j8 |
C |
T |
17: 38,263,276 (GRCm39) |
G213E |
possibly damaging |
Het |
| Or1e22 |
A |
C |
11: 73,377,200 (GRCm39) |
V150G |
probably benign |
Het |
| Or2j3 |
A |
T |
17: 38,616,203 (GRCm39) |
S50T |
probably benign |
Het |
| Or2y1 |
A |
T |
11: 49,385,497 (GRCm39) |
I46F |
probably damaging |
Het |
| Plpbp |
T |
C |
8: 27,539,259 (GRCm39) |
V126A |
probably damaging |
Het |
| Pold2 |
A |
G |
11: 5,823,454 (GRCm39) |
L325P |
possibly damaging |
Het |
| Ppp1r12c |
A |
C |
7: 4,486,650 (GRCm39) |
S480A |
probably damaging |
Het |
| Pum1 |
T |
C |
4: 130,428,359 (GRCm39) |
S124P |
possibly damaging |
Het |
| Pwp2 |
C |
G |
10: 78,014,925 (GRCm39) |
G353A |
probably damaging |
Het |
| Reln |
C |
A |
5: 22,184,000 (GRCm39) |
Q1666H |
probably damaging |
Het |
| Rnf19a |
T |
C |
15: 36,266,071 (GRCm39) |
I9V |
probably benign |
Het |
| Ryr2 |
T |
C |
13: 11,784,764 (GRCm39) |
H1063R |
probably benign |
Het |
| Samd14 |
C |
G |
11: 94,914,426 (GRCm39) |
D361E |
probably damaging |
Het |
| Samd15 |
A |
T |
12: 87,248,617 (GRCm39) |
N365I |
probably damaging |
Het |
| Sec16b |
A |
G |
1: 157,358,882 (GRCm39) |
H105R |
probably benign |
Het |
| Sez6 |
T |
C |
11: 77,844,329 (GRCm39) |
S51P |
probably benign |
Het |
| Sh3bp1 |
T |
A |
15: 78,789,350 (GRCm39) |
L236Q |
probably damaging |
Het |
| Sspo |
C |
T |
6: 48,434,274 (GRCm39) |
T991I |
probably damaging |
Het |
| Suco |
A |
T |
1: 161,687,069 (GRCm39) |
L97* |
probably null |
Het |
| Tab1 |
C |
A |
15: 80,032,497 (GRCm39) |
R35S |
probably benign |
Het |
| Tet3 |
C |
A |
6: 83,381,145 (GRCm39) |
S341I |
possibly damaging |
Het |
| Tlr1 |
A |
T |
5: 65,083,043 (GRCm39) |
D511E |
probably benign |
Het |
| Tmem132b |
A |
C |
5: 125,862,963 (GRCm39) |
D656A |
probably damaging |
Het |
| Tmtc4 |
T |
A |
14: 123,179,400 (GRCm39) |
|
probably null |
Het |
| Trmo |
T |
C |
4: 46,380,158 (GRCm39) |
T404A |
probably damaging |
Het |
| Trpm1 |
A |
G |
7: 63,880,016 (GRCm39) |
K790E |
probably damaging |
Het |
| Ulk4 |
C |
A |
9: 120,997,250 (GRCm39) |
R774M |
probably null |
Het |
| Ush2a |
C |
T |
1: 188,184,015 (GRCm39) |
L1440F |
probably benign |
Het |
| Usp16 |
A |
G |
16: 87,277,795 (GRCm39) |
K682E |
probably damaging |
Het |
| Virma |
T |
C |
4: 11,540,511 (GRCm39) |
S1471P |
probably benign |
Het |
| Vmn1r177 |
A |
T |
7: 23,565,111 (GRCm39) |
I255N |
probably damaging |
Het |
| Vmn2r61 |
A |
T |
7: 41,916,076 (GRCm39) |
R230* |
probably null |
Het |
| Vps13c |
T |
A |
9: 67,900,295 (GRCm39) |
F3671L |
probably benign |
Het |
| Washc5 |
T |
C |
15: 59,231,189 (GRCm39) |
N358S |
possibly damaging |
Het |
| Wdr72 |
A |
G |
9: 74,058,899 (GRCm39) |
K331E |
probably damaging |
Het |
| Zfp986 |
A |
T |
4: 145,625,805 (GRCm39) |
K155I |
probably benign |
Het |
|
| Other mutations in Patj |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:Patj
|
APN |
4 |
98,353,343 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00095:Patj
|
APN |
4 |
98,423,799 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL00517:Patj
|
APN |
4 |
98,329,308 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL00802:Patj
|
APN |
4 |
98,312,643 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL01064:Patj
|
APN |
4 |
98,385,210 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01110:Patj
|
APN |
4 |
98,301,261 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01407:Patj
|
APN |
4 |
98,301,287 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
IGL01821:Patj
|
APN |
4 |
98,344,448 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02399:Patj
|
APN |
4 |
98,480,173 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02494:Patj
|
APN |
4 |
98,592,224 (GRCm39) |
splice site |
probably benign |
|
|
IGL02803:Patj
|
APN |
4 |
98,314,301 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02931:Patj
|
APN |
4 |
98,299,410 (GRCm39) |
splice site |
probably benign |
|
|
IGL03017:Patj
|
APN |
4 |
98,353,264 (GRCm39) |
splice site |
probably benign |
|
|
IGL03115:Patj
|
APN |
4 |
98,332,040 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03209:Patj
|
APN |
4 |
98,353,377 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL03377:Patj
|
APN |
4 |
98,353,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
D4186:Patj
|
UTSW |
4 |
98,526,999 (GRCm39) |
missense |
probably benign |
0.17 |
|
PIT4531001:Patj
|
UTSW |
4 |
98,329,327 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0136:Patj
|
UTSW |
4 |
98,555,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0294:Patj
|
UTSW |
4 |
98,385,285 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0376:Patj
|
UTSW |
4 |
98,457,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0463:Patj
|
UTSW |
4 |
98,562,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0465:Patj
|
UTSW |
4 |
98,423,744 (GRCm39) |
splice site |
probably null |
|
|
R0466:Patj
|
UTSW |
4 |
98,576,393 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0544:Patj
|
UTSW |
4 |
98,457,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0624:Patj
|
UTSW |
4 |
98,569,472 (GRCm39) |
splice site |
probably benign |
|
|
R0657:Patj
|
UTSW |
4 |
98,555,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1281:Patj
|
UTSW |
4 |
98,304,932 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1393:Patj
|
UTSW |
4 |
98,312,648 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1480:Patj
|
UTSW |
4 |
98,357,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1667:Patj
|
UTSW |
4 |
98,301,264 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1728:Patj
|
UTSW |
4 |
98,320,017 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1729:Patj
|
UTSW |
4 |
98,320,017 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1797:Patj
|
UTSW |
4 |
98,575,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1818:Patj
|
UTSW |
4 |
98,511,885 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1880:Patj
|
UTSW |
4 |
98,385,477 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2009:Patj
|
UTSW |
4 |
98,344,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2090:Patj
|
UTSW |
4 |
98,325,560 (GRCm39) |
unclassified |
probably benign |
|
|
R2120:Patj
|
UTSW |
4 |
98,344,462 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2180:Patj
|
UTSW |
4 |
98,411,739 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2655:Patj
|
UTSW |
4 |
98,325,687 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R3156:Patj
|
UTSW |
4 |
98,562,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3749:Patj
|
UTSW |
4 |
98,357,837 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3767:Patj
|
UTSW |
4 |
98,569,456 (GRCm39) |
nonsense |
probably null |
|
|
R3913:Patj
|
UTSW |
4 |
98,457,338 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3917:Patj
|
UTSW |
4 |
98,480,245 (GRCm39) |
nonsense |
probably null |
|
|
R3918:Patj
|
UTSW |
4 |
98,344,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4299:Patj
|
UTSW |
4 |
98,565,558 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4355:Patj
|
UTSW |
4 |
98,538,691 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4471:Patj
|
UTSW |
4 |
98,423,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4762:Patj
|
UTSW |
4 |
98,293,807 (GRCm39) |
nonsense |
probably null |
|
|
R4877:Patj
|
UTSW |
4 |
98,457,295 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4945:Patj
|
UTSW |
4 |
98,383,301 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5274:Patj
|
UTSW |
4 |
98,407,218 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5343:Patj
|
UTSW |
4 |
98,564,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5554:Patj
|
UTSW |
4 |
98,342,633 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5688:Patj
|
UTSW |
4 |
98,409,047 (GRCm39) |
nonsense |
probably null |
|
|
R5880:Patj
|
UTSW |
4 |
98,299,382 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5972:Patj
|
UTSW |
4 |
98,457,290 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6149:Patj
|
UTSW |
4 |
98,312,562 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R6192:Patj
|
UTSW |
4 |
98,344,394 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6265:Patj
|
UTSW |
4 |
98,357,804 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6350:Patj
|
UTSW |
4 |
98,293,855 (GRCm39) |
missense |
probably benign |
0.26 |
|
R6363:Patj
|
UTSW |
4 |
98,320,097 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6434:Patj
|
UTSW |
4 |
98,379,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6496:Patj
|
UTSW |
4 |
98,304,989 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6896:Patj
|
UTSW |
4 |
98,314,287 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7039:Patj
|
UTSW |
4 |
98,457,315 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7040:Patj
|
UTSW |
4 |
98,329,317 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7052:Patj
|
UTSW |
4 |
98,565,497 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7066:Patj
|
UTSW |
4 |
98,301,434 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7236:Patj
|
UTSW |
4 |
98,299,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7242:Patj
|
UTSW |
4 |
98,480,170 (GRCm39) |
missense |
probably benign |
0.26 |
|
R7260:Patj
|
UTSW |
4 |
98,304,970 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7412:Patj
|
UTSW |
4 |
98,299,376 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7493:Patj
|
UTSW |
4 |
98,383,298 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7570:Patj
|
UTSW |
4 |
98,312,737 (GRCm39) |
splice site |
probably null |
|
|
R7571:Patj
|
UTSW |
4 |
98,457,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7626:Patj
|
UTSW |
4 |
98,435,224 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7658:Patj
|
UTSW |
4 |
98,576,416 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7664:Patj
|
UTSW |
4 |
98,385,187 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7669:Patj
|
UTSW |
4 |
98,407,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7796:Patj
|
UTSW |
4 |
98,435,220 (GRCm39) |
start codon destroyed |
probably benign |
0.05 |
|
R7870:Patj
|
UTSW |
4 |
98,312,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7883:Patj
|
UTSW |
4 |
98,499,372 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7948:Patj
|
UTSW |
4 |
98,312,547 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8050:Patj
|
UTSW |
4 |
98,427,201 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8183:Patj
|
UTSW |
4 |
98,562,466 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8239:Patj
|
UTSW |
4 |
98,570,308 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8483:Patj
|
UTSW |
4 |
98,312,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8546:Patj
|
UTSW |
4 |
98,325,634 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8746:Patj
|
UTSW |
4 |
98,394,067 (GRCm39) |
intron |
probably benign |
|
|
R8844:Patj
|
UTSW |
4 |
98,480,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8905:Patj
|
UTSW |
4 |
98,385,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8912:Patj
|
UTSW |
4 |
98,385,565 (GRCm39) |
missense |
|
|
|
R8959:Patj
|
UTSW |
4 |
98,480,212 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9083:Patj
|
UTSW |
4 |
98,401,871 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9173:Patj
|
UTSW |
4 |
98,526,958 (GRCm39) |
missense |
probably benign |
|
|
R9206:Patj
|
UTSW |
4 |
98,427,310 (GRCm39) |
missense |
unknown |
|
|
R9208:Patj
|
UTSW |
4 |
98,427,310 (GRCm39) |
missense |
unknown |
|
|
R9347:Patj
|
UTSW |
4 |
98,576,484 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9560:Patj
|
UTSW |
4 |
98,570,289 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9609:Patj
|
UTSW |
4 |
98,576,473 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9617:Patj
|
UTSW |
4 |
98,393,991 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9658:Patj
|
UTSW |
4 |
98,353,377 (GRCm39) |
missense |
probably null |
1.00 |
|
R9756:Patj
|
UTSW |
4 |
98,565,535 (GRCm39) |
missense |
probably benign |
|
|
Z1176:Patj
|
UTSW |
4 |
98,564,555 (GRCm39) |
nonsense |
probably null |
|
|
Z1176:Patj
|
UTSW |
4 |
98,499,367 (GRCm39) |
missense |
probably benign |
0.11 |
|
Z1177:Patj
|
UTSW |
4 |
98,385,411 (GRCm39) |
missense |
probably benign |
0.01 |
|
| Predicted Primers |
PCR Primer
(F):5'- TAAGCGTCTATAGAATAGCAGCAG -3'
(R):5'- GGCAAATTTGTCTTCCAAGTTCATG -3'
Sequencing Primer
(F):5'- TAGCAGCAGAGTACTTGCCGTG -3'
(R):5'- ATACCAATTGAGTTCCAAACTTACC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation