Incidental Mutation 'R7451:Dhx57'
| ID |
577760 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dhx57
|
| Ensembl Gene |
ENSMUSG00000035051 |
| Gene Name |
DExH-box helicase 57 |
| Synonyms |
|
| MMRRC Submission |
045525-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.190)
|
| Stock # |
R7451 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
80545733-80597620 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 80554542 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Glutamic Acid
at position 1228
(V1228E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000083742
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038166]
[ENSMUST00000086555]
|
| AlphaFold |
Q6P5D3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000038166
AA Change: V1175E
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000041069
Gene: ENSMUSG00000035051
AA Change: V1175E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
116 |
125 |
N/A |
INTRINSIC |
|
UBA
|
129 |
166 |
1.04e-3 |
SMART |
|
ZnF_C3H1
|
246 |
272 |
4.07e-6 |
SMART |
|
low complexity region
|
357 |
368 |
N/A |
INTRINSIC |
|
low complexity region
|
381 |
390 |
N/A |
INTRINSIC |
|
low complexity region
|
423 |
432 |
N/A |
INTRINSIC |
|
DEXDc
|
490 |
678 |
1.27e-28 |
SMART |
|
Blast:DEXDc
|
688 |
752 |
2e-28 |
BLAST |
|
HELICc
|
810 |
918 |
3.22e-16 |
SMART |
|
HA2
|
984 |
1074 |
1.64e-24 |
SMART |
|
Pfam:OB_NTP_bind
|
1113 |
1262 |
1.5e-20 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000086555
AA Change: V1228E
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000083742
Gene: ENSMUSG00000035051
AA Change: V1228E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
169 |
178 |
N/A |
INTRINSIC |
|
UBA
|
182 |
219 |
1.04e-3 |
SMART |
|
ZnF_C3H1
|
299 |
325 |
4.07e-6 |
SMART |
|
low complexity region
|
410 |
421 |
N/A |
INTRINSIC |
|
low complexity region
|
434 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
476 |
485 |
N/A |
INTRINSIC |
|
DEXDc
|
543 |
731 |
1.27e-28 |
SMART |
|
Blast:DEXDc
|
741 |
805 |
1e-28 |
BLAST |
|
HELICc
|
863 |
971 |
3.22e-16 |
SMART |
|
HA2
|
1037 |
1127 |
1.64e-24 |
SMART |
|
Pfam:OB_NTP_bind
|
1166 |
1315 |
8.5e-25 |
PFAM |
|
| Meta Mutation Damage Score |
0.9276 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.2%
|
| Validation Efficiency |
100% (84/84) |
| Allele List at MGI |
All alleles(25) : Gene trapped(25)
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcb6 |
A |
G |
1: 75,148,797 (GRCm39) |
I794T |
probably damaging |
Het |
| Abcc5 |
T |
A |
16: 20,193,820 (GRCm39) |
H767L |
probably damaging |
Het |
| Adgrb2 |
A |
T |
4: 129,908,350 (GRCm39) |
M1031L |
probably damaging |
Het |
| Akna |
T |
A |
4: 63,296,904 (GRCm39) |
M891L |
probably benign |
Het |
| Aloxe3 |
C |
A |
11: 69,033,746 (GRCm39) |
T620K |
possibly damaging |
Het |
| Amph |
A |
G |
13: 19,261,538 (GRCm39) |
Y63C |
probably damaging |
Het |
| Asprv1 |
A |
G |
6: 86,605,930 (GRCm39) |
I259V |
probably benign |
Het |
| Atp7b |
C |
T |
8: 22,504,700 (GRCm39) |
W652* |
probably null |
Het |
| Atp8a2 |
C |
T |
14: 60,028,630 (GRCm39) |
D946N |
probably null |
Het |
| BC024063 |
T |
A |
10: 81,944,576 (GRCm39) |
N65K |
probably benign |
Het |
| Bean1 |
A |
T |
8: 104,940,628 (GRCm39) |
M154L |
probably benign |
Het |
| Bltp1 |
G |
T |
3: 37,076,956 (GRCm39) |
|
probably null |
Het |
| Cacna1c |
C |
T |
6: 118,570,981 (GRCm39) |
V2181M |
unknown |
Het |
| Cacna1g |
A |
G |
11: 94,319,901 (GRCm39) |
I1425T |
probably damaging |
Het |
| Caskin2 |
A |
G |
11: 115,702,981 (GRCm39) |
|
probably benign |
Het |
| Ccng2 |
C |
G |
5: 93,421,202 (GRCm39) |
S237R |
probably benign |
Het |
| Cfap97d1 |
A |
T |
11: 101,882,283 (GRCm39) |
N147I |
possibly damaging |
Het |
| Cfd |
T |
A |
10: 79,727,362 (GRCm39) |
V43E |
probably damaging |
Het |
| Chd9 |
GCCCC |
GCCC |
8: 91,760,418 (GRCm39) |
|
probably null |
Het |
| Chd9 |
T |
A |
8: 91,760,446 (GRCm39) |
S2064T |
probably benign |
Het |
| Cpsf2 |
T |
G |
12: 101,967,051 (GRCm39) |
V646G |
possibly damaging |
Het |
| Ctif |
T |
C |
18: 75,652,874 (GRCm39) |
D461G |
possibly damaging |
Het |
| Cyp3a41a |
T |
A |
5: 145,636,550 (GRCm39) |
E414D |
probably benign |
Het |
| Dagla |
A |
G |
19: 10,230,719 (GRCm39) |
V544A |
probably damaging |
Het |
| Eif2b3 |
T |
A |
4: 116,909,993 (GRCm39) |
L176* |
probably null |
Het |
| Fbxw26 |
T |
A |
9: 109,561,691 (GRCm39) |
I168L |
probably benign |
Het |
| Flt3 |
T |
A |
5: 147,286,477 (GRCm39) |
Y703F |
probably damaging |
Het |
| Frmpd1 |
C |
T |
4: 45,279,558 (GRCm39) |
P761L |
probably benign |
Het |
| Gabrd |
A |
G |
4: 155,472,916 (GRCm39) |
V89A |
possibly damaging |
Het |
| Galnt14 |
A |
T |
17: 73,881,804 (GRCm39) |
H98Q |
probably benign |
Het |
| Gli3 |
T |
C |
13: 15,900,876 (GRCm39) |
V1421A |
possibly damaging |
Het |
| Gprin2 |
A |
G |
14: 33,917,762 (GRCm39) |
S3P |
probably damaging |
Het |
| Ifi211 |
T |
G |
1: 173,727,058 (GRCm39) |
D362A |
probably damaging |
Het |
| Lars1 |
G |
T |
18: 42,335,615 (GRCm39) |
T1167K |
probably benign |
Het |
| Lce1b |
T |
C |
3: 92,563,207 (GRCm39) |
S109G |
unknown |
Het |
| Lrp2 |
T |
G |
2: 69,343,677 (GRCm39) |
E894A |
probably damaging |
Het |
| Mamdc4 |
A |
G |
2: 25,454,473 (GRCm39) |
V1081A |
possibly damaging |
Het |
| Mcub |
T |
C |
3: 129,710,752 (GRCm39) |
S227G |
possibly damaging |
Het |
| Mki67 |
A |
G |
7: 135,301,080 (GRCm39) |
I1318T |
probably benign |
Het |
| Mybl2 |
C |
T |
2: 162,914,626 (GRCm39) |
T248I |
possibly damaging |
Het |
| Myo9b |
A |
T |
8: 71,804,832 (GRCm39) |
H1441L |
probably benign |
Het |
| Nav2 |
T |
A |
7: 49,202,577 (GRCm39) |
|
probably null |
Het |
| Neb |
C |
T |
2: 52,091,466 (GRCm39) |
V5339I |
probably benign |
Het |
| Nktr |
T |
A |
9: 121,558,722 (GRCm39) |
S88T |
probably damaging |
Het |
| Nup155 |
C |
T |
15: 8,175,091 (GRCm39) |
Q963* |
probably null |
Het |
| Oas1c |
A |
C |
5: 120,940,207 (GRCm39) |
L320V |
possibly damaging |
Het |
| Or10ak14 |
C |
T |
4: 118,610,884 (GRCm39) |
A286T |
probably benign |
Het |
| Or10d1b |
G |
A |
9: 39,613,423 (GRCm39) |
T214I |
probably damaging |
Het |
| Or1o11 |
C |
A |
17: 37,757,196 (GRCm39) |
S261R |
probably damaging |
Het |
| Or2t46 |
A |
G |
11: 58,472,516 (GRCm39) |
Y282C |
probably damaging |
Het |
| Or4a81 |
A |
G |
2: 89,619,453 (GRCm39) |
M81T |
probably benign |
Het |
| Or52b4i |
T |
C |
7: 102,191,461 (GRCm39) |
I106T |
probably benign |
Het |
| Pcdhga7 |
A |
G |
18: 37,849,057 (GRCm39) |
S355G |
possibly damaging |
Het |
| Pde11a |
C |
T |
2: 75,853,117 (GRCm39) |
V834I |
possibly damaging |
Het |
| Pdzrn4 |
A |
T |
15: 92,667,948 (GRCm39) |
D700V |
possibly damaging |
Het |
| Pif1 |
C |
A |
9: 65,495,630 (GRCm39) |
P180Q |
probably benign |
Het |
| Pkig |
G |
T |
2: 163,563,083 (GRCm39) |
E5* |
probably null |
Het |
| Pla2r1 |
T |
A |
2: 60,365,346 (GRCm39) |
M75L |
probably damaging |
Het |
| Pllp |
T |
C |
8: 95,402,871 (GRCm39) |
S157G |
probably damaging |
Het |
| Ppfia1 |
A |
T |
7: 144,061,947 (GRCm39) |
H566Q |
probably benign |
Het |
| Ptpn13 |
A |
G |
5: 103,674,961 (GRCm39) |
D646G |
probably benign |
Het |
| Rab11fip5 |
T |
A |
6: 85,318,538 (GRCm39) |
T784S |
probably benign |
Het |
| Rad51ap2 |
T |
G |
12: 11,507,982 (GRCm39) |
S635A |
probably benign |
Het |
| Ranbp17 |
A |
T |
11: 33,234,114 (GRCm39) |
|
probably null |
Het |
| Rce1 |
C |
T |
19: 4,675,081 (GRCm39) |
G111D |
probably damaging |
Het |
| Rcor3 |
C |
A |
1: 191,822,173 (GRCm39) |
G8V |
probably damaging |
Het |
| Rhox4d |
G |
A |
X: 36,700,645 (GRCm39) |
G191E |
unknown |
Het |
| Rimbp2 |
C |
T |
5: 128,865,435 (GRCm39) |
V631I |
probably benign |
Het |
| Scai |
T |
C |
2: 39,015,148 (GRCm39) |
T94A |
probably damaging |
Het |
| Sfmbt1 |
G |
A |
14: 30,538,768 (GRCm39) |
A796T |
probably benign |
Het |
| Slc6a11 |
C |
A |
6: 114,222,644 (GRCm39) |
Y546* |
probably null |
Het |
| Slc7a2 |
T |
C |
8: 41,365,686 (GRCm39) |
S506P |
probably damaging |
Het |
| Synj2 |
T |
A |
17: 6,080,066 (GRCm39) |
N1098K |
possibly damaging |
Het |
| Tmem177 |
G |
A |
1: 119,837,971 (GRCm39) |
A236V |
probably damaging |
Het |
| Togaram1 |
T |
A |
12: 65,043,749 (GRCm39) |
D1249E |
probably damaging |
Het |
| Trav17 |
A |
T |
14: 54,044,096 (GRCm39) |
M1L |
probably damaging |
Het |
| Trim25 |
C |
A |
11: 88,906,563 (GRCm39) |
A433D |
possibly damaging |
Het |
| Trim69 |
T |
C |
2: 121,998,508 (GRCm39) |
F160S |
probably benign |
Het |
| Trio |
A |
T |
15: 27,747,999 (GRCm39) |
V1407E |
probably benign |
Het |
| Trpm7 |
A |
T |
2: 126,668,657 (GRCm39) |
M753K |
probably damaging |
Het |
| Ttc12 |
G |
T |
9: 49,383,179 (GRCm39) |
A75E |
probably benign |
Het |
| Uchl4 |
A |
T |
9: 64,143,013 (GRCm39) |
I165L |
probably benign |
Het |
| Uvrag |
A |
T |
7: 98,790,120 (GRCm39) |
L13Q |
unknown |
Het |
| Wwc2 |
G |
A |
8: 48,317,610 (GRCm39) |
R656W |
not run |
Het |
|
| Other mutations in Dhx57 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00642:Dhx57
|
APN |
17 |
80,582,405 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00811:Dhx57
|
APN |
17 |
80,560,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01389:Dhx57
|
APN |
17 |
80,588,652 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL01468:Dhx57
|
APN |
17 |
80,563,039 (GRCm39) |
nonsense |
probably null |
|
|
IGL01908:Dhx57
|
APN |
17 |
80,558,872 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01965:Dhx57
|
APN |
17 |
80,576,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02147:Dhx57
|
APN |
17 |
80,567,752 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02275:Dhx57
|
APN |
17 |
80,582,268 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02349:Dhx57
|
APN |
17 |
80,563,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02405:Dhx57
|
APN |
17 |
80,562,979 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02588:Dhx57
|
APN |
17 |
80,576,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02673:Dhx57
|
APN |
17 |
80,574,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02836:Dhx57
|
APN |
17 |
80,574,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02889:Dhx57
|
APN |
17 |
80,554,581 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL03085:Dhx57
|
APN |
17 |
80,565,526 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
P0014:Dhx57
|
UTSW |
17 |
80,582,620 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4377001:Dhx57
|
UTSW |
17 |
80,571,404 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0100:Dhx57
|
UTSW |
17 |
80,582,585 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R0100:Dhx57
|
UTSW |
17 |
80,582,585 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R0129:Dhx57
|
UTSW |
17 |
80,546,343 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0200:Dhx57
|
UTSW |
17 |
80,558,902 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0309:Dhx57
|
UTSW |
17 |
80,582,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0375:Dhx57
|
UTSW |
17 |
80,565,550 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0396:Dhx57
|
UTSW |
17 |
80,582,226 (GRCm39) |
missense |
probably benign |
0.34 |
|
R0520:Dhx57
|
UTSW |
17 |
80,565,604 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0554:Dhx57
|
UTSW |
17 |
80,567,665 (GRCm39) |
nonsense |
probably null |
|
|
R0661:Dhx57
|
UTSW |
17 |
80,576,293 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0883:Dhx57
|
UTSW |
17 |
80,577,800 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0900:Dhx57
|
UTSW |
17 |
80,583,011 (GRCm39) |
missense |
probably benign |
|
|
R0963:Dhx57
|
UTSW |
17 |
80,582,956 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1469:Dhx57
|
UTSW |
17 |
80,561,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1469:Dhx57
|
UTSW |
17 |
80,561,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1660:Dhx57
|
UTSW |
17 |
80,553,157 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1707:Dhx57
|
UTSW |
17 |
80,582,655 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1822:Dhx57
|
UTSW |
17 |
80,560,514 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1853:Dhx57
|
UTSW |
17 |
80,582,308 (GRCm39) |
nonsense |
probably null |
|
|
R1942:Dhx57
|
UTSW |
17 |
80,572,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2043:Dhx57
|
UTSW |
17 |
80,560,509 (GRCm39) |
splice site |
probably benign |
|
|
R2106:Dhx57
|
UTSW |
17 |
80,582,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2127:Dhx57
|
UTSW |
17 |
80,580,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2183:Dhx57
|
UTSW |
17 |
80,582,760 (GRCm39) |
missense |
probably benign |
0.07 |
|
R2249:Dhx57
|
UTSW |
17 |
80,588,663 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2400:Dhx57
|
UTSW |
17 |
80,567,845 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2404:Dhx57
|
UTSW |
17 |
80,561,733 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2513:Dhx57
|
UTSW |
17 |
80,549,378 (GRCm39) |
splice site |
probably null |
|
|
R2869:Dhx57
|
UTSW |
17 |
80,558,805 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2869:Dhx57
|
UTSW |
17 |
80,558,805 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2870:Dhx57
|
UTSW |
17 |
80,558,805 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2870:Dhx57
|
UTSW |
17 |
80,558,805 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2871:Dhx57
|
UTSW |
17 |
80,558,805 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2871:Dhx57
|
UTSW |
17 |
80,558,805 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2874:Dhx57
|
UTSW |
17 |
80,558,805 (GRCm39) |
missense |
probably benign |
0.22 |
|
R3819:Dhx57
|
UTSW |
17 |
80,572,503 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3964:Dhx57
|
UTSW |
17 |
80,572,541 (GRCm39) |
nonsense |
probably null |
|
|
R4535:Dhx57
|
UTSW |
17 |
80,582,511 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4666:Dhx57
|
UTSW |
17 |
80,582,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4788:Dhx57
|
UTSW |
17 |
80,582,760 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4822:Dhx57
|
UTSW |
17 |
80,549,596 (GRCm39) |
splice site |
probably null |
|
|
R4863:Dhx57
|
UTSW |
17 |
80,560,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4988:Dhx57
|
UTSW |
17 |
80,558,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5391:Dhx57
|
UTSW |
17 |
80,582,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5559:Dhx57
|
UTSW |
17 |
80,561,808 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5644:Dhx57
|
UTSW |
17 |
80,546,302 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R5997:Dhx57
|
UTSW |
17 |
80,553,235 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6090:Dhx57
|
UTSW |
17 |
80,571,375 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6177:Dhx57
|
UTSW |
17 |
80,580,395 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6283:Dhx57
|
UTSW |
17 |
80,582,234 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6802:Dhx57
|
UTSW |
17 |
80,582,750 (GRCm39) |
missense |
probably benign |
0.43 |
|
R6924:Dhx57
|
UTSW |
17 |
80,546,244 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7151:Dhx57
|
UTSW |
17 |
80,580,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7386:Dhx57
|
UTSW |
17 |
80,575,006 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7393:Dhx57
|
UTSW |
17 |
80,563,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7602:Dhx57
|
UTSW |
17 |
80,582,290 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7733:Dhx57
|
UTSW |
17 |
80,572,503 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7748:Dhx57
|
UTSW |
17 |
80,572,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7749:Dhx57
|
UTSW |
17 |
80,546,287 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7772:Dhx57
|
UTSW |
17 |
80,580,507 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8213:Dhx57
|
UTSW |
17 |
80,582,585 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8370:Dhx57
|
UTSW |
17 |
80,553,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8371:Dhx57
|
UTSW |
17 |
80,582,919 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8403:Dhx57
|
UTSW |
17 |
80,585,718 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8467:Dhx57
|
UTSW |
17 |
80,561,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8690:Dhx57
|
UTSW |
17 |
80,577,794 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R9210:Dhx57
|
UTSW |
17 |
80,576,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9212:Dhx57
|
UTSW |
17 |
80,576,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9447:Dhx57
|
UTSW |
17 |
80,549,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9562:Dhx57
|
UTSW |
17 |
80,561,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9669:Dhx57
|
UTSW |
17 |
80,553,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9717:Dhx57
|
UTSW |
17 |
80,582,447 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Dhx57
|
UTSW |
17 |
80,558,777 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dhx57
|
UTSW |
17 |
80,553,234 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- AACTGGGAATCCTTTCGCGC -3'
(R):5'- TTAACCACATCCCAGTCGAGAG -3'
Sequencing Primer
(F):5'- CTCTGTGCAGCTACTGAAGATGAC -3'
(R):5'- GTGTCTGTTCATAGCAGTAGAACCC -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation