Incidental Mutation 'R4779:Ube3b'
| ID |
368137 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ube3b
|
| Ensembl Gene |
ENSMUSG00000029577 |
| Gene Name |
ubiquitin protein ligase E3B |
| Synonyms |
|
| MMRRC Submission |
045240-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4779 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
114518668-114559230 bp(+) (GRCm39) |
| Type of Mutation |
splice site (6 bp from exon) |
| DNA Base Change (assembly) |
T to C
at 114542778 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000073652
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000074002]
[ENSMUST00000074002]
[ENSMUST00000130169]
|
| AlphaFold |
Q9ES34 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000074002
|
| SMART Domains |
Protein: ENSMUSP00000073652
Gene: ENSMUSG00000029577
| Domain | Start | End | E-Value | Type |
|---|
|
IQ
|
28 |
50 |
1.17e-2 |
SMART |
|
low complexity region
|
310 |
327 |
N/A |
INTRINSIC |
|
low complexity region
|
412 |
428 |
N/A |
INTRINSIC |
|
low complexity region
|
470 |
488 |
N/A |
INTRINSIC |
|
HECTc
|
697 |
1070 |
2.15e-110 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000074002
|
| SMART Domains |
Protein: ENSMUSP00000073652
Gene: ENSMUSG00000029577
| Domain | Start | End | E-Value | Type |
|---|
|
IQ
|
28 |
50 |
1.17e-2 |
SMART |
|
low complexity region
|
310 |
327 |
N/A |
INTRINSIC |
|
low complexity region
|
412 |
428 |
N/A |
INTRINSIC |
|
low complexity region
|
470 |
488 |
N/A |
INTRINSIC |
|
HECTc
|
697 |
1070 |
2.15e-110 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000130169
|
| SMART Domains |
Protein: ENSMUSP00000138723
Gene: ENSMUSG00000029577
| Domain | Start | End | E-Value | Type |
|---|
|
IQ
|
28 |
50 |
1.17e-2 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150630
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183408
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000196651
|
| SMART Domains |
Protein: ENSMUSP00000143455
Gene: ENSMUSG00000029577
| Domain | Start | End | E-Value | Type |
|---|
|
HECTc
|
122 |
495 |
1.1e-112 |
SMART |
|
| Meta Mutation Damage Score |
0.9755 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 93.8%
|
| Validation Efficiency |
98% (95/97) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin-protein ligases. This gene encodes a member of the E3 ubiquitin-conjugating enzyme family which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and transfers the ubiquitin to the targeted substrates. A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases. Shorter isoforms of this protein which lack the C-terminal HECT domain are therefore unlikely to bind E2 enzymes. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2012]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit preweaning lethality, reduced fertility, decreased growth, reduced grip strength, impaired hearing, eye inflammation and decreased cholesterol level. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930562C15Rik |
T |
A |
16: 4,667,613 (GRCm39) |
S335T |
unknown |
Het |
| 4933421I07Rik |
T |
A |
7: 42,097,455 (GRCm39) |
H13L |
possibly damaging |
Het |
| 6030468B19Rik |
A |
G |
11: 117,696,834 (GRCm39) |
T185A |
probably benign |
Het |
| Abcc1 |
T |
A |
16: 14,228,635 (GRCm39) |
V294E |
probably benign |
Het |
| Abhd16b |
A |
G |
2: 181,135,253 (GRCm39) |
T52A |
possibly damaging |
Het |
| Actl7a |
A |
T |
4: 56,743,632 (GRCm39) |
N53I |
probably benign |
Het |
| Ankmy1 |
T |
C |
1: 92,814,445 (GRCm39) |
E354G |
probably benign |
Het |
| Arap1 |
T |
C |
7: 101,053,574 (GRCm39) |
F1301S |
probably damaging |
Het |
| Arfgef1 |
A |
T |
1: 10,223,958 (GRCm39) |
W1447R |
probably damaging |
Het |
| Atoh7 |
ATGGCGCT |
AT |
10: 62,936,187 (GRCm39) |
|
probably benign |
Het |
| Ccl24 |
T |
A |
5: 135,601,811 (GRCm39) |
T6S |
possibly damaging |
Het |
| Cep152 |
G |
T |
2: 125,410,812 (GRCm39) |
P1292Q |
possibly damaging |
Het |
| Cfap46 |
T |
C |
7: 139,239,731 (GRCm39) |
|
probably benign |
Het |
| Chd6 |
A |
T |
2: 160,791,477 (GRCm39) |
S2627T |
probably damaging |
Het |
| Chd8 |
A |
T |
14: 52,468,963 (GRCm39) |
S552T |
probably damaging |
Het |
| Ciita |
C |
A |
16: 10,329,230 (GRCm39) |
L502M |
probably damaging |
Het |
| Clic1 |
T |
C |
17: 35,271,463 (GRCm39) |
F31S |
probably damaging |
Het |
| Cntnap1 |
T |
A |
11: 101,068,898 (GRCm39) |
I147N |
possibly damaging |
Het |
| Cplane1 |
T |
C |
15: 8,248,322 (GRCm39) |
S1624P |
probably benign |
Het |
| Crispld1 |
T |
A |
1: 17,819,831 (GRCm39) |
D276E |
probably benign |
Het |
| Cspg4 |
A |
T |
9: 56,793,092 (GRCm39) |
N276Y |
probably damaging |
Het |
| Cspg4b |
A |
T |
13: 113,504,870 (GRCm39) |
N2000Y |
possibly damaging |
Het |
| Cwf19l2 |
A |
G |
9: 3,410,035 (GRCm39) |
M55V |
possibly damaging |
Het |
| Cyp2c69 |
T |
C |
19: 39,866,038 (GRCm39) |
N185S |
probably benign |
Het |
| Dop1b |
T |
C |
16: 93,553,969 (GRCm39) |
I301T |
probably damaging |
Het |
| Epg5 |
T |
C |
18: 78,034,580 (GRCm39) |
V1443A |
probably benign |
Het |
| Ephb4 |
T |
C |
5: 137,363,964 (GRCm39) |
V612A |
probably benign |
Het |
| Fcgbp |
T |
A |
7: 27,794,362 (GRCm39) |
C1189S |
probably damaging |
Het |
| Fgfr2 |
T |
G |
7: 129,786,923 (GRCm39) |
|
probably benign |
Het |
| Fmn2 |
A |
G |
1: 174,437,461 (GRCm39) |
E1144G |
probably damaging |
Het |
| Fmo3 |
T |
C |
1: 162,796,407 (GRCm39) |
Y55C |
probably damaging |
Het |
| Frmpd1 |
A |
G |
4: 45,229,865 (GRCm39) |
T11A |
probably damaging |
Het |
| Ghdc |
G |
T |
11: 100,660,929 (GRCm39) |
Q79K |
possibly damaging |
Het |
| Gm11677 |
C |
T |
11: 111,615,537 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5591 |
T |
C |
7: 38,221,680 (GRCm39) |
T130A |
probably damaging |
Het |
| Heg1 |
T |
G |
16: 33,540,142 (GRCm39) |
D367E |
probably benign |
Het |
| Igkv13-84 |
C |
T |
6: 68,916,894 (GRCm39) |
P64S |
probably damaging |
Het |
| Il10rb |
T |
A |
16: 91,211,545 (GRCm39) |
S128T |
possibly damaging |
Het |
| Il15ra |
T |
A |
2: 11,723,117 (GRCm39) |
I47N |
probably damaging |
Het |
| Il33 |
C |
A |
19: 29,936,311 (GRCm39) |
S207* |
probably null |
Het |
| Itgb7 |
A |
G |
15: 102,132,848 (GRCm39) |
Y155H |
possibly damaging |
Het |
| Kdm5a |
A |
G |
6: 120,346,060 (GRCm39) |
|
probably benign |
Het |
| Kif11 |
G |
A |
19: 37,406,397 (GRCm39) |
V987I |
probably benign |
Het |
| Krtap19-2 |
G |
A |
16: 88,670,762 (GRCm39) |
|
probably benign |
Het |
| Krtap24-1 |
T |
A |
16: 88,408,417 (GRCm39) |
R236S |
probably damaging |
Het |
| L3mbtl2 |
A |
G |
15: 81,566,813 (GRCm39) |
I406V |
probably benign |
Het |
| Lrp2 |
A |
T |
2: 69,290,059 (GRCm39) |
H3593Q |
possibly damaging |
Het |
| Mavs |
G |
T |
2: 131,082,285 (GRCm39) |
W56C |
probably damaging |
Het |
| Mn1 |
C |
T |
5: 111,567,526 (GRCm39) |
P499S |
probably damaging |
Het |
| Ntn5 |
T |
A |
7: 45,340,895 (GRCm39) |
C178S |
probably damaging |
Het |
| Nufip2 |
A |
G |
11: 77,577,154 (GRCm39) |
H34R |
unknown |
Het |
| Or5p51 |
T |
A |
7: 107,444,755 (GRCm39) |
M62L |
possibly damaging |
Het |
| Or6f2 |
T |
A |
7: 139,756,363 (GRCm39) |
L110Q |
probably damaging |
Het |
| Osbpl10 |
C |
T |
9: 114,938,598 (GRCm39) |
S86L |
probably damaging |
Het |
| Pitpna |
T |
A |
11: 75,511,153 (GRCm39) |
M242K |
possibly damaging |
Het |
| Pnpla6 |
T |
C |
8: 3,572,838 (GRCm39) |
V345A |
probably benign |
Het |
| Polk |
A |
G |
13: 96,632,999 (GRCm39) |
|
probably null |
Het |
| Polr3k |
A |
G |
2: 181,506,340 (GRCm39) |
Y30C |
probably damaging |
Het |
| Pramel6 |
A |
G |
2: 87,339,941 (GRCm39) |
H235R |
probably benign |
Het |
| Ptpra |
G |
A |
2: 130,379,537 (GRCm39) |
V364I |
probably damaging |
Het |
| Recql |
A |
G |
6: 142,309,426 (GRCm39) |
|
probably benign |
Het |
| Ring1 |
T |
C |
17: 34,241,263 (GRCm39) |
|
probably benign |
Het |
| Rufy4 |
T |
C |
1: 74,186,822 (GRCm39) |
C537R |
probably damaging |
Het |
| Samsn1 |
C |
A |
16: 75,744,177 (GRCm39) |
|
noncoding transcript |
Het |
| Scara5 |
A |
G |
14: 65,968,198 (GRCm39) |
H157R |
probably benign |
Het |
| Sdc3 |
C |
T |
4: 130,546,376 (GRCm39) |
P245L |
probably damaging |
Het |
| Slc18b1 |
T |
A |
10: 23,696,767 (GRCm39) |
M318K |
possibly damaging |
Het |
| Slc26a10 |
C |
T |
10: 127,009,224 (GRCm39) |
A638T |
possibly damaging |
Het |
| Slc35f2 |
T |
A |
9: 53,717,013 (GRCm39) |
W259R |
possibly damaging |
Het |
| Spata13 |
G |
A |
14: 60,991,356 (GRCm39) |
W366* |
probably null |
Het |
| Sptlc3 |
A |
G |
2: 139,431,509 (GRCm39) |
T344A |
probably benign |
Het |
| Tap1 |
T |
C |
17: 34,412,865 (GRCm39) |
V560A |
probably damaging |
Het |
| Tbc1d1 |
T |
C |
5: 64,435,389 (GRCm39) |
|
probably null |
Het |
| Tlr11 |
A |
G |
14: 50,598,707 (GRCm39) |
Y231C |
possibly damaging |
Het |
| Tmem245 |
A |
T |
4: 56,936,468 (GRCm39) |
S230T |
possibly damaging |
Het |
| Tnnt3 |
C |
T |
7: 142,068,020 (GRCm39) |
|
probably benign |
Het |
| Traf7 |
C |
G |
17: 24,729,412 (GRCm39) |
|
probably benign |
Het |
| Tshz2 |
A |
G |
2: 169,804,601 (GRCm39) |
|
probably benign |
Het |
| Tshz3 |
T |
C |
7: 36,468,397 (GRCm39) |
S129P |
probably damaging |
Het |
| Ttc6 |
A |
T |
12: 57,776,237 (GRCm39) |
N1727I |
probably damaging |
Het |
| Ttc7b |
A |
G |
12: 100,369,621 (GRCm39) |
S383P |
probably damaging |
Het |
| Tulp3 |
T |
A |
6: 128,300,083 (GRCm39) |
I448F |
probably damaging |
Het |
| Vav1 |
G |
A |
17: 57,603,552 (GRCm39) |
V84I |
probably damaging |
Het |
| Vav3 |
A |
T |
3: 109,416,110 (GRCm39) |
K243I |
possibly damaging |
Het |
| Vmn1r25 |
T |
A |
6: 57,956,011 (GRCm39) |
I93F |
probably damaging |
Het |
| Vmn2r73 |
C |
T |
7: 85,520,923 (GRCm39) |
W348* |
probably null |
Het |
| Zdbf2 |
A |
G |
1: 63,342,397 (GRCm39) |
R259G |
possibly damaging |
Het |
|
| Other mutations in Ube3b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00754:Ube3b
|
APN |
5 |
114,553,348 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL01154:Ube3b
|
APN |
5 |
114,544,313 (GRCm39) |
missense |
probably null |
0.86 |
|
IGL02632:Ube3b
|
APN |
5 |
114,536,902 (GRCm39) |
missense |
probably benign |
|
|
IGL02850:Ube3b
|
APN |
5 |
114,544,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02878:Ube3b
|
APN |
5 |
114,542,778 (GRCm39) |
splice site |
probably null |
|
|
IGL02881:Ube3b
|
APN |
5 |
114,550,945 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0003:Ube3b
|
UTSW |
5 |
114,536,912 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0071:Ube3b
|
UTSW |
5 |
114,557,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0071:Ube3b
|
UTSW |
5 |
114,557,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0076:Ube3b
|
UTSW |
5 |
114,546,278 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0076:Ube3b
|
UTSW |
5 |
114,546,278 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0111:Ube3b
|
UTSW |
5 |
114,528,437 (GRCm39) |
splice site |
probably benign |
|
|
R0309:Ube3b
|
UTSW |
5 |
114,557,530 (GRCm39) |
splice site |
probably benign |
|
|
R0718:Ube3b
|
UTSW |
5 |
114,540,616 (GRCm39) |
nonsense |
probably null |
|
|
R1344:Ube3b
|
UTSW |
5 |
114,556,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1350:Ube3b
|
UTSW |
5 |
114,544,198 (GRCm39) |
splice site |
probably null |
|
|
R1418:Ube3b
|
UTSW |
5 |
114,556,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1732:Ube3b
|
UTSW |
5 |
114,525,506 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1764:Ube3b
|
UTSW |
5 |
114,542,678 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1975:Ube3b
|
UTSW |
5 |
114,537,926 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R2014:Ube3b
|
UTSW |
5 |
114,549,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2015:Ube3b
|
UTSW |
5 |
114,549,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2041:Ube3b
|
UTSW |
5 |
114,525,294 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2074:Ube3b
|
UTSW |
5 |
114,553,316 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2202:Ube3b
|
UTSW |
5 |
114,527,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2205:Ube3b
|
UTSW |
5 |
114,527,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3826:Ube3b
|
UTSW |
5 |
114,538,012 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3829:Ube3b
|
UTSW |
5 |
114,538,012 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3830:Ube3b
|
UTSW |
5 |
114,538,012 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3927:Ube3b
|
UTSW |
5 |
114,553,741 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3974:Ube3b
|
UTSW |
5 |
114,550,491 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4049:Ube3b
|
UTSW |
5 |
114,550,931 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4096:Ube3b
|
UTSW |
5 |
114,531,147 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R4261:Ube3b
|
UTSW |
5 |
114,536,489 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4415:Ube3b
|
UTSW |
5 |
114,550,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4688:Ube3b
|
UTSW |
5 |
114,531,139 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4824:Ube3b
|
UTSW |
5 |
114,553,787 (GRCm39) |
splice site |
probably null |
|
|
R4868:Ube3b
|
UTSW |
5 |
114,536,488 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4953:Ube3b
|
UTSW |
5 |
114,539,471 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5013:Ube3b
|
UTSW |
5 |
114,545,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5057:Ube3b
|
UTSW |
5 |
114,544,318 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5117:Ube3b
|
UTSW |
5 |
114,557,692 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5131:Ube3b
|
UTSW |
5 |
114,545,607 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5498:Ube3b
|
UTSW |
5 |
114,556,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5564:Ube3b
|
UTSW |
5 |
114,527,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5572:Ube3b
|
UTSW |
5 |
114,544,240 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5580:Ube3b
|
UTSW |
5 |
114,553,384 (GRCm39) |
missense |
probably benign |
|
|
R5596:Ube3b
|
UTSW |
5 |
114,544,221 (GRCm39) |
splice site |
probably null |
|
|
R5843:Ube3b
|
UTSW |
5 |
114,550,360 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5910:Ube3b
|
UTSW |
5 |
114,553,370 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6591:Ube3b
|
UTSW |
5 |
114,546,185 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6691:Ube3b
|
UTSW |
5 |
114,546,185 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7148:Ube3b
|
UTSW |
5 |
114,544,313 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7334:Ube3b
|
UTSW |
5 |
114,553,742 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R7438:Ube3b
|
UTSW |
5 |
114,556,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7438:Ube3b
|
UTSW |
5 |
114,553,345 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R7640:Ube3b
|
UTSW |
5 |
114,553,384 (GRCm39) |
missense |
probably benign |
|
|
R7825:Ube3b
|
UTSW |
5 |
114,539,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7958:Ube3b
|
UTSW |
5 |
114,539,484 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8025:Ube3b
|
UTSW |
5 |
114,546,270 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8058:Ube3b
|
UTSW |
5 |
114,544,846 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R8087:Ube3b
|
UTSW |
5 |
114,550,550 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8182:Ube3b
|
UTSW |
5 |
114,530,199 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R8322:Ube3b
|
UTSW |
5 |
114,540,747 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8465:Ube3b
|
UTSW |
5 |
114,528,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8682:Ube3b
|
UTSW |
5 |
114,550,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8708:Ube3b
|
UTSW |
5 |
114,531,151 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8758:Ube3b
|
UTSW |
5 |
114,553,261 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R8784:Ube3b
|
UTSW |
5 |
114,526,800 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9058:Ube3b
|
UTSW |
5 |
114,553,300 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9072:Ube3b
|
UTSW |
5 |
114,542,607 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9116:Ube3b
|
UTSW |
5 |
114,542,837 (GRCm39) |
intron |
probably benign |
|
|
R9537:Ube3b
|
UTSW |
5 |
114,525,245 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9596:Ube3b
|
UTSW |
5 |
114,527,171 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9632:Ube3b
|
UTSW |
5 |
114,553,370 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9710:Ube3b
|
UTSW |
5 |
114,553,370 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0017:Ube3b
|
UTSW |
5 |
114,553,646 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
| Predicted Primers |
PCR Primer
(F):5'- TACGTACCTGGATGACCTGC -3'
(R):5'- TGCCACATGCTTTCTGAATGTC -3'
Sequencing Primer
(F):5'- TGGATGACCTGCTGCCCAAG -3'
(R):5'- ATGGCTTCCTGCAATGTTGTC -3'
|
| Posted On |
2015-12-29 |
Incidental Mutation