Mutagenetix > Incidental Mutation

Incidental Mutation 'R5615:Pkd1l3'

438197

Institutional Source

Beutler Lab

Gene Symbol

Pkd1l3

Ensembl Gene

ENSMUSG00000048827

Gene Name

polycystic kidney disease 1 like 3

Synonyms

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R5615 (G1)

Quality Score

Status

Not validated

Chromosome

Chromosomal Location

109614517-109674386 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 109630210 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Valine at position 756 (I756V)

Ref Sequence

ENSEMBL: ENSMUSP00000104865 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057344] [ENSMUST00000109242] [ENSMUST00000212537]

AlphaFold

Q2EG98

Predicted Effect

probably benign
Transcript: ENSMUST00000057344

SMART Domains

Protein: ENSMUSP00000051512
Gene: ENSMUSG00000048827

Domain	Start	End	E-Value	Type
signal peptide	1	20	N/A	INTRINSIC
CLECT	26	142	4.25e-1	SMART
internal_repeat_2	143	245	2.25e-8	PROSPERO
low complexity region	246	270	N/A	INTRINSIC
low complexity region	272	296	N/A	INTRINSIC
low complexity region	298	322	N/A	INTRINSIC
low complexity region	324	348	N/A	INTRINSIC
internal_repeat_1	349	431	1.22e-8	PROSPERO
internal_repeat_2	378	466	2.25e-8	PROSPERO
internal_repeat_1	518	731	1.22e-8	PROSPERO
GPS	1007	1056	3.62e-5	SMART
transmembrane domain	1075	1094	N/A	INTRINSIC
LH2	1119	1238	1.01e-9	SMART
transmembrane domain	1282	1304	N/A	INTRINSIC
transmembrane domain	1319	1341	N/A	INTRINSIC
low complexity region	1398	1408	N/A	INTRINSIC
low complexity region	1451	1460	N/A	INTRINSIC
low complexity region	1484	1497	N/A	INTRINSIC
transmembrane domain	1534	1556	N/A	INTRINSIC
transmembrane domain	1576	1595	N/A	INTRINSIC
Pfam:PKD_channel	1695	2110	2.8e-86	PFAM
Pfam:Ion_trans	1858	2114	2.9e-9	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000109242
AA Change: I756V

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000104865
Gene: ENSMUSG00000048827
AA Change: I756V

Domain	Start	End	E-Value	Type
signal peptide	1	20	N/A	INTRINSIC
CLECT	26	142	4.25e-1	SMART
internal_repeat_2	143	245	2.63e-8	PROSPERO
low complexity region	246	270	N/A	INTRINSIC
low complexity region	272	296	N/A	INTRINSIC
low complexity region	298	322	N/A	INTRINSIC
low complexity region	324	348	N/A	INTRINSIC
internal_repeat_1	349	440	3.96e-14	PROSPERO
internal_repeat_2	378	466	2.63e-8	PROSPERO
internal_repeat_1	518	724	3.96e-14	PROSPERO
GPS	1017	1066	3.62e-5	SMART
transmembrane domain	1085	1104	N/A	INTRINSIC
LH2	1129	1248	1.01e-9	SMART
transmembrane domain	1292	1314	N/A	INTRINSIC
transmembrane domain	1329	1351	N/A	INTRINSIC
low complexity region	1408	1418	N/A	INTRINSIC
low complexity region	1461	1470	N/A	INTRINSIC
low complexity region	1494	1507	N/A	INTRINSIC
transmembrane domain	1544	1566	N/A	INTRINSIC
transmembrane domain	1586	1605	N/A	INTRINSIC
Pfam:PKD_channel	1705	2120	1.3e-86	PFAM
Pfam:Ion_trans	1868	2124	4.3e-9	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000212537

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000213034

Coding Region Coverage

1x: 99.8%
3x: 99.5%
10x: 97.6%
20x: 92.4%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores.[provided by RefSeq, Apr 2009]
PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and grossly normal and exhibit normal taste responsiveness in various behavioral and electrophysiological tests of taste function. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 59 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
0610010F05Rik	A	T	11: 23,606,759 (GRCm38)	L407H	probably damaging	Het
Abca12	A	T	1: 71,307,059 (GRCm38)	L884H	probably damaging	Het
Ahr	A	G	12: 35,503,885 (GRCm38)	V745A	probably benign	Het
Ankrd17	A	T	5: 90,283,436 (GRCm38)	S830T	possibly damaging	Het
Aox1	A	G	1: 58,096,966 (GRCm38)	T1123A	probably benign	Het
Arhgef11	T	C	3: 87,722,485 (GRCm38)		probably null	Het
Bcas3	T	A	11: 85,470,761 (GRCm38)	C250S	probably damaging	Het
Bckdk	T	C	7: 127,907,317 (GRCm38)	I272T	probably damaging	Het
Cacna1e	T	C	1: 154,412,170 (GRCm38)	K1897E	probably damaging	Het
Cd180	A	T	13: 102,706,203 (GRCm38)	I586F	probably benign	Het
Cep290	A	G	10: 100,531,150 (GRCm38)	D1121G	probably damaging	Het
Clasrp	A	G	7: 19,586,447 (GRCm38)		probably benign	Het
Col27a1	G	T	4: 63,281,114 (GRCm38)	K912N	probably damaging	Het
Dock4	G	T	12: 40,649,480 (GRCm38)	R231L	probably benign	Het
Ell	G	A	8: 70,590,732 (GRCm38)	S505N	probably benign	Het
Ephb6	A	G	6: 41,619,291 (GRCm38)	T833A	probably benign	Het
Hemk1	T	A	9: 107,330,824 (GRCm38)		probably null	Het
Hjurp	GT	GTT	1: 88,266,524 (GRCm38)		probably null	Het
Hspa12a	T	C	19: 58,804,650 (GRCm38)	I368V	possibly damaging	Het
Igkv3-3	A	T	6: 70,687,230 (GRCm38)	T19S	probably benign	Het
Itpr1	G	A	6: 108,488,600 (GRCm38)	A2158T	possibly damaging	Het
Lancl2	T	C	6: 57,722,511 (GRCm38)	Y104H	probably damaging	Het
Leng8	G	T	7: 4,144,958 (GRCm38)	E634*	probably null	Het
Lrrk1	A	T	7: 66,287,615 (GRCm38)	C930S	probably damaging	Het
Lvrn	C	T	18: 46,850,328 (GRCm38)	S46L	possibly damaging	Het
Mcidas	G	A	13: 112,997,425 (GRCm38)	V148I	probably benign	Het
Mprip	A	T	11: 59,758,487 (GRCm38)	T1006S	probably benign	Het
Mrgprb3	T	A	7: 48,643,486 (GRCm38)	M106L	probably benign	Het
Mroh2a	GCCC	GC	1: 88,232,257 (GRCm38)		probably null	Het
Mtor	G	A	4: 148,538,276 (GRCm38)	V1938I	possibly damaging	Het
Muc2	A	G	7: 141,691,203 (GRCm38)	D46G	probably damaging	Het
Nfkb2	G	T	19: 46,307,567 (GRCm38)	E170D	probably benign	Het
Olfr1113	T	A	2: 87,213,739 (GRCm38)	F282L	probably benign	Het
Olfr811	A	T	10: 129,801,767 (GRCm38)	C253S	probably damaging	Het
Osbp2	C	T	11: 3,863,356 (GRCm38)	G171D	probably benign	Het
Otud6b	A	T	4: 14,818,187 (GRCm38)	M238K	possibly damaging	Het
Pcdhac2	G	T	18: 37,146,424 (GRCm38)	G819V	probably benign	Het
Pcdhac2	G	A	18: 37,146,423 (GRCm38)	G819R	probably benign	Het
Pcdhga12	T	G	18: 37,768,079 (GRCm38)	S655A	probably damaging	Het
Plekhd1	T	A	12: 80,720,590 (GRCm38)	S251T	probably damaging	Het
Ppp2r1a	A	T	17: 20,958,987 (GRCm38)	T96S	probably benign	Het
Qser1	A	C	2: 104,789,694 (GRCm38)	S258A	possibly damaging	Het
Rsph4a	G	A	10: 33,909,328 (GRCm38)	A412T	probably benign	Het
Sass6	T	A	3: 116,607,486 (GRCm38)	C159S	probably benign	Het
Scaf4	T	C	16: 90,251,960 (GRCm38)	Q322R	unknown	Het
Sema6d	C	T	2: 124,656,901 (GRCm38)	H244Y	probably damaging	Het
Sigirr	T	G	7: 141,092,719 (GRCm38)	L163F	probably damaging	Het
Spata31d1c	C	A	13: 65,035,264 (GRCm38)	L207I	possibly damaging	Het
Tacstd2	A	G	6: 67,535,049 (GRCm38)	F220L	probably damaging	Het
Tdpoz4	A	T	3: 93,797,499 (GRCm38)	T368S	probably benign	Het
Tnxb	C	A	17: 34,683,418 (GRCm38)	Q1082K	probably damaging	Het
Trim41	GCCTAGGCGCCCA	G	11: 48,807,365 (GRCm38)		probably benign	Het
Trpm6	C	T	19: 18,829,933 (GRCm38)	R1014C	probably damaging	Het
Ugt1a10	TTCATCA	TTCA	1: 88,216,158 (GRCm38)		probably benign	Het
Vmn2r114	ATTT	ATT	17: 23,290,932 (GRCm38)		probably null	Het
Vmn2r61	T	A	7: 42,267,253 (GRCm38)	M430K	probably benign	Het
Vmn2r61	A	G	7: 42,300,493 (GRCm38)	E779G	probably damaging	Het
Zfp599	T	C	9: 22,253,869 (GRCm38)	D70G	probably benign	Het
Zmym1	A	T	4: 127,049,398 (GRCm38)	I301N	probably damaging	Het

Other mutations in Pkd1l3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00336:Pkd1l3	APN	8	109,630,237 (GRCm38)	missense	possibly damaging	0.53
IGL00562:Pkd1l3	APN	8	109,656,147 (GRCm38)	missense	possibly damaging	0.53
IGL00563:Pkd1l3	APN	8	109,656,147 (GRCm38)	missense	possibly damaging	0.53
IGL01061:Pkd1l3	APN	8	109,638,706 (GRCm38)	missense	probably damaging	1.00
IGL01105:Pkd1l3	APN	8	109,662,241 (GRCm38)	missense	possibly damaging	0.81
IGL01574:Pkd1l3	APN	8	109,623,771 (GRCm38)	missense	probably benign	0.01
IGL01597:Pkd1l3	APN	8	109,623,521 (GRCm38)	missense	probably benign	0.33
IGL01634:Pkd1l3	APN	8	109,667,525 (GRCm38)	critical splice acceptor site	probably null
IGL01645:Pkd1l3	APN	8	109,635,302 (GRCm38)	missense	possibly damaging	0.59
IGL01770:Pkd1l3	APN	8	109,648,502 (GRCm38)	critical splice acceptor site	probably null
IGL01837:Pkd1l3	APN	8	109,630,166 (GRCm38)	missense	possibly damaging	0.85
IGL01862:Pkd1l3	APN	8	109,631,276 (GRCm38)	critical splice acceptor site	probably null
IGL01938:Pkd1l3	APN	8	109,635,301 (GRCm38)	missense	probably benign	0.00
IGL01990:Pkd1l3	APN	8	109,660,806 (GRCm38)	missense	probably damaging	1.00
IGL02056:Pkd1l3	APN	8	109,631,378 (GRCm38)	missense	probably benign	0.14
IGL02069:Pkd1l3	APN	8	109,635,380 (GRCm38)	missense	probably damaging	1.00
IGL02086:Pkd1l3	APN	8	109,665,585 (GRCm38)	missense	probably damaging	1.00
IGL02152:Pkd1l3	APN	8	109,669,292 (GRCm38)	missense	probably damaging	1.00
IGL02209:Pkd1l3	APN	8	109,638,664 (GRCm38)	missense	probably damaging	1.00
IGL02213:Pkd1l3	APN	8	109,631,345 (GRCm38)	missense	probably damaging	1.00
IGL02218:Pkd1l3	APN	8	109,660,802 (GRCm38)	missense	possibly damaging	0.92
IGL02225:Pkd1l3	APN	8	109,638,678 (GRCm38)	missense	probably damaging	1.00
IGL02252:Pkd1l3	APN	8	109,631,076 (GRCm38)	missense	possibly damaging	0.92
IGL02351:Pkd1l3	APN	8	109,646,497 (GRCm38)	unclassified	probably benign
IGL02358:Pkd1l3	APN	8	109,646,497 (GRCm38)	unclassified	probably benign
IGL02369:Pkd1l3	APN	8	109,616,345 (GRCm38)	missense	unknown
IGL02481:Pkd1l3	APN	8	109,614,782 (GRCm38)	missense	unknown
IGL02505:Pkd1l3	APN	8	109,633,216 (GRCm38)	missense	probably damaging	1.00
IGL02506:Pkd1l3	APN	8	109,647,500 (GRCm38)	missense	probably damaging	1.00
IGL02535:Pkd1l3	APN	8	109,640,890 (GRCm38)	nonsense	probably null
IGL02715:Pkd1l3	APN	8	109,626,826 (GRCm38)	missense	probably damaging	0.96
IGL02979:Pkd1l3	APN	8	109,662,104 (GRCm38)	splice site	probably benign
IGL03059:Pkd1l3	APN	8	109,648,367 (GRCm38)	missense	probably damaging	1.00
IGL03090:Pkd1l3	APN	8	109,655,533 (GRCm38)	nonsense	probably null
IGL03206:Pkd1l3	APN	8	109,623,713 (GRCm38)	missense	probably benign	0.18
IGL03328:Pkd1l3	APN	8	109,662,106 (GRCm38)	splice site	probably benign
BB006:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
PIT4453001:Pkd1l3	UTSW	8	109,660,801 (GRCm38)	missense	probably damaging	0.99
PIT4468001:Pkd1l3	UTSW	8	109,664,499 (GRCm38)	missense	possibly damaging	0.85
R0001:Pkd1l3	UTSW	8	109,628,633 (GRCm38)	splice site	probably benign
R0066:Pkd1l3	UTSW	8	109,620,471 (GRCm38)	missense	unknown
R0066:Pkd1l3	UTSW	8	109,620,471 (GRCm38)	missense	unknown
R0233:Pkd1l3	UTSW	8	109,650,780 (GRCm38)	nonsense	probably null
R0233:Pkd1l3	UTSW	8	109,650,780 (GRCm38)	nonsense	probably null
R0255:Pkd1l3	UTSW	8	109,638,754 (GRCm38)	missense	probably damaging	1.00
R0288:Pkd1l3	UTSW	8	109,646,499 (GRCm38)	splice site	probably null
R0311:Pkd1l3	UTSW	8	109,623,663 (GRCm38)	missense	probably benign	0.33
R0311:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0403:Pkd1l3	UTSW	8	109,623,663 (GRCm38)	missense	probably benign	0.33
R0403:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0441:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0446:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0465:Pkd1l3	UTSW	8	109,623,663 (GRCm38)	missense	probably benign	0.33
R0465:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0466:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0467:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0468:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0488:Pkd1l3	UTSW	8	109,623,663 (GRCm38)	missense	probably benign	0.33
R0488:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0515:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0534:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0650:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0689:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R1422:Pkd1l3	UTSW	8	109,621,708 (GRCm38)	missense	unknown
R1464:Pkd1l3	UTSW	8	109,636,427 (GRCm38)	splice site	probably benign
R1467:Pkd1l3	UTSW	8	109,616,368 (GRCm38)	missense	unknown
R1467:Pkd1l3	UTSW	8	109,616,368 (GRCm38)	missense	unknown
R1469:Pkd1l3	UTSW	8	109,646,953 (GRCm38)	missense	possibly damaging	0.72
R1469:Pkd1l3	UTSW	8	109,646,953 (GRCm38)	missense	possibly damaging	0.72
R1509:Pkd1l3	UTSW	8	109,640,770 (GRCm38)	missense	probably damaging	0.99
R1561:Pkd1l3	UTSW	8	109,614,813 (GRCm38)	missense	unknown
R1574:Pkd1l3	UTSW	8	109,614,813 (GRCm38)	missense	unknown
R1599:Pkd1l3	UTSW	8	109,636,384 (GRCm38)	missense	probably benign	0.01
R1688:Pkd1l3	UTSW	8	109,623,818 (GRCm38)	missense	probably benign	0.18
R1792:Pkd1l3	UTSW	8	109,632,605 (GRCm38)	missense	probably damaging	1.00
R1818:Pkd1l3	UTSW	8	109,648,406 (GRCm38)	missense	probably benign	0.03
R1896:Pkd1l3	UTSW	8	109,624,199 (GRCm38)	missense	possibly damaging	0.92
R2105:Pkd1l3	UTSW	8	109,647,573 (GRCm38)	nonsense	probably null
R2185:Pkd1l3	UTSW	8	109,633,195 (GRCm38)	missense	possibly damaging	0.95
R2192:Pkd1l3	UTSW	8	109,620,524 (GRCm38)	missense	unknown
R2260:Pkd1l3	UTSW	8	109,623,636 (GRCm38)	missense	probably benign	0.18
R2363:Pkd1l3	UTSW	8	109,628,709 (GRCm38)	missense	probably benign	0.01
R2418:Pkd1l3	UTSW	8	109,670,721 (GRCm38)	makesense	probably null
R2435:Pkd1l3	UTSW	8	109,650,702 (GRCm38)	missense	probably benign	0.07
R2443:Pkd1l3	UTSW	8	109,623,815 (GRCm38)	missense	probably benign	0.18
R2850:Pkd1l3	UTSW	8	109,623,990 (GRCm38)	missense	possibly damaging	0.92
R2910:Pkd1l3	UTSW	8	109,667,636 (GRCm38)	splice site	probably benign
R3755:Pkd1l3	UTSW	8	109,632,539 (GRCm38)	missense	probably damaging	1.00
R3791:Pkd1l3	UTSW	8	109,636,317 (GRCm38)	missense	probably damaging	0.99
R3905:Pkd1l3	UTSW	8	109,646,879 (GRCm38)	missense	probably benign	0.02
R4027:Pkd1l3	UTSW	8	109,623,971 (GRCm38)	missense	possibly damaging	0.68
R4028:Pkd1l3	UTSW	8	109,623,971 (GRCm38)	missense	possibly damaging	0.68
R4029:Pkd1l3	UTSW	8	109,623,971 (GRCm38)	missense	possibly damaging	0.68
R4274:Pkd1l3	UTSW	8	109,624,119 (GRCm38)	missense	possibly damaging	0.92
R4461:Pkd1l3	UTSW	8	109,632,713 (GRCm38)	splice site	probably null
R4893:Pkd1l3	UTSW	8	109,638,394 (GRCm38)	missense	probably benign	0.15
R4907:Pkd1l3	UTSW	8	109,640,843 (GRCm38)	missense	probably damaging	0.99
R5037:Pkd1l3	UTSW	8	109,665,636 (GRCm38)	missense	probably damaging	1.00
R5045:Pkd1l3	UTSW	8	109,623,155 (GRCm38)	missense	unknown
R5207:Pkd1l3	UTSW	8	109,633,191 (GRCm38)	missense	probably damaging	1.00
R5307:Pkd1l3	UTSW	8	109,640,792 (GRCm38)	missense	probably damaging	1.00
R5408:Pkd1l3	UTSW	8	109,667,052 (GRCm38)	missense	probably damaging	1.00
R5595:Pkd1l3	UTSW	8	109,655,520 (GRCm38)	missense	probably damaging	1.00
R5623:Pkd1l3	UTSW	8	109,623,719 (GRCm38)	missense	possibly damaging	0.53
R5896:Pkd1l3	UTSW	8	109,626,836 (GRCm38)	missense	probably damaging	1.00
R6101:Pkd1l3	UTSW	8	109,640,846 (GRCm38)	missense	probably damaging	1.00
R6105:Pkd1l3	UTSW	8	109,640,846 (GRCm38)	missense	probably damaging	1.00
R6170:Pkd1l3	UTSW	8	109,623,179 (GRCm38)	missense	unknown
R6330:Pkd1l3	UTSW	8	109,646,909 (GRCm38)	missense	probably benign	0.00
R6346:Pkd1l3	UTSW	8	109,631,384 (GRCm38)	missense	probably damaging	0.98
R6395:Pkd1l3	UTSW	8	109,623,963 (GRCm38)	missense	probably benign	0.20
R6475:Pkd1l3	UTSW	8	109,623,212 (GRCm38)	missense	unknown
R6480:Pkd1l3	UTSW	8	109,638,387 (GRCm38)	nonsense	probably null
R6519:Pkd1l3	UTSW	8	109,628,772 (GRCm38)	missense	probably benign
R6654:Pkd1l3	UTSW	8	109,624,283 (GRCm38)	missense	probably benign	0.23
R6717:Pkd1l3	UTSW	8	109,614,769 (GRCm38)	missense	unknown
R6733:Pkd1l3	UTSW	8	109,648,494 (GRCm38)	splice site	probably null
R6753:Pkd1l3	UTSW	8	109,624,449 (GRCm38)	missense	probably damaging	1.00
R6777:Pkd1l3	UTSW	8	109,626,814 (GRCm38)	missense	probably benign	0.00
R6901:Pkd1l3	UTSW	8	109,614,614 (GRCm38)	missense	unknown
R6975:Pkd1l3	UTSW	8	109,660,907 (GRCm38)	missense	possibly damaging	0.73
R6991:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7018:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7083:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7139:Pkd1l3	UTSW	8	109,636,340 (GRCm38)	missense	probably damaging	0.96
R7153:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7235:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7238:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7252:Pkd1l3	UTSW	8	109,660,698 (GRCm38)	missense	probably benign	0.01
R7296:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7309:Pkd1l3	UTSW	8	109,648,261 (GRCm38)	splice site	probably null
R7362:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7462:Pkd1l3	UTSW	8	109,628,777 (GRCm38)	missense	probably benign	0.00
R7470:Pkd1l3	UTSW	8	109,638,376 (GRCm38)	missense	probably benign	0.09
R7478:Pkd1l3	UTSW	8	109,633,315 (GRCm38)	missense	probably damaging	1.00
R7483:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7516:Pkd1l3	UTSW	8	109,635,229 (GRCm38)	missense	probably damaging	1.00
R7553:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7559:Pkd1l3	UTSW	8	109,624,440 (GRCm38)	missense	probably benign	0.03
R7650:Pkd1l3	UTSW	8	109,672,585 (GRCm38)	missense	probably benign	0.23
R7654:Pkd1l3	UTSW	8	109,638,417 (GRCm38)	missense	probably damaging	1.00
R7742:Pkd1l3	UTSW	8	109,614,572 (GRCm38)	missense	unknown
R7749:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7751:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7755:Pkd1l3	UTSW	8	109,630,166 (GRCm38)	missense	possibly damaging	0.85
R7816:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7831:Pkd1l3	UTSW	8	109,631,358 (GRCm38)	missense	possibly damaging	0.47
R7835:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7849:Pkd1l3	UTSW	8	109,623,788 (GRCm38)	small deletion	probably benign
R7917:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7929:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7952:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8054:Pkd1l3	UTSW	8	109,646,376 (GRCm38)	missense	probably damaging	1.00
R8098:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8099:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8276:Pkd1l3	UTSW	8	109,670,721 (GRCm38)	makesense	probably null
R8352:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8376:Pkd1l3	UTSW	8	109,623,788 (GRCm38)	small deletion	probably benign
R8377:Pkd1l3	UTSW	8	109,635,350 (GRCm38)	missense	probably benign	0.08
R8398:Pkd1l3	UTSW	8	109,623,888 (GRCm38)	missense	possibly damaging	0.93
R8399:Pkd1l3	UTSW	8	109,623,888 (GRCm38)	missense	possibly damaging	0.93
R8400:Pkd1l3	UTSW	8	109,623,888 (GRCm38)	missense	possibly damaging	0.93
R8412:Pkd1l3	UTSW	8	109,633,390 (GRCm38)	missense	possibly damaging	0.85
R8530:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8539:Pkd1l3	UTSW	8	109,636,287 (GRCm38)	missense	probably damaging	1.00
R8546:Pkd1l3	UTSW	8	109,666,983 (GRCm38)	missense	possibly damaging	0.52
R8558:Pkd1l3	UTSW	8	109,635,380 (GRCm38)	missense	probably damaging	1.00
R8719:Pkd1l3	UTSW	8	109,614,623 (GRCm38)	missense	unknown
R8769:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8797:Pkd1l3	UTSW	8	109,648,314 (GRCm38)	missense	probably benign	0.15
R8840:Pkd1l3	UTSW	8	109,623,210 (GRCm38)	missense	unknown
R8846:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8874:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8893:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8956:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8963:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8968:Pkd1l3	UTSW	8	109,623,788 (GRCm38)	small deletion	probably benign
R9035:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9054:Pkd1l3	UTSW	8	109,665,672 (GRCm38)	missense	probably benign	0.08
R9058:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9119:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9134:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9138:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9158:Pkd1l3	UTSW	8	109,667,575 (GRCm38)	nonsense	probably null
R9180:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9181:Pkd1l3	UTSW	8	109,648,686 (GRCm38)	missense	probably damaging	0.98
R9218:Pkd1l3	UTSW	8	109,655,496 (GRCm38)	nonsense	probably null
R9249:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9269:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9338:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9383:Pkd1l3	UTSW	8	109,623,969 (GRCm38)	small deletion	probably benign
R9396:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9423:Pkd1l3	UTSW	8	109,623,680 (GRCm38)	missense	possibly damaging	0.53
R9514:Pkd1l3	UTSW	8	109,669,217 (GRCm38)	missense	probably damaging	1.00
R9515:Pkd1l3	UTSW	8	109,669,217 (GRCm38)	missense	probably damaging	1.00
R9567:Pkd1l3	UTSW	8	109,667,541 (GRCm38)	missense	probably damaging	0.99
R9668:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9684:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9748:Pkd1l3	UTSW	8	109,646,923 (GRCm38)	missense	probably benign	0.00
R9778:Pkd1l3	UTSW	8	109,631,305 (GRCm38)	missense	probably benign	0.00
RF016:Pkd1l3	UTSW	8	109,623,542 (GRCm38)	missense	probably benign	0.18
RF029:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
X0026:Pkd1l3	UTSW	8	109,614,553 (GRCm38)	missense	probably null
Z1176:Pkd1l3	UTSW	8	109,623,242 (GRCm38)	missense	unknown
Z31818:Pkd1l3	UTSW	8	109,669,292 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GTTCTACCATGTTTGGAAAGTTCAT -3'
(R):5'- GGGGCAGCCAAAGGAATATTTT -3'

Sequencing Primer
(F):5'- CATCTCAAAAGAGCTGTTCTCAG -3'
(R):5'- GGATTTACCCAATGGTCACCTAG -3'

Posted On

2016-10-26