Incidental Mutation 'R1865:Plxnd1'
| ID |
208616 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnd1
|
| Ensembl Gene |
ENSMUSG00000030123 |
| Gene Name |
plexin D1 |
| Synonyms |
6230425C21Rik, b2b1863Clo, b2b553Clo |
| MMRRC Submission |
039888-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1865 (G1)
|
| Quality Score |
186 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
115931772-115971966 bp(-) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
A to T
at 115946402 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000015511]
|
| AlphaFold |
Q3UH93 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000015511
AA Change: M853K
PolyPhen 2
Score 0.021 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000015511
Gene: ENSMUSG00000030123
AA Change: M853K
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
48 |
N/A |
INTRINSIC |
|
Sema
|
61 |
531 |
6.52e-90 |
SMART |
|
PSI
|
550 |
603 |
6.06e-12 |
SMART |
|
PSI
|
703 |
755 |
1.06e-2 |
SMART |
|
Blast:PSI
|
850 |
891 |
9e-20 |
BLAST |
|
IPT
|
892 |
981 |
4.43e-20 |
SMART |
|
IPT
|
982 |
1068 |
6.61e-19 |
SMART |
|
IPT
|
1070 |
1149 |
6.13e-14 |
SMART |
|
transmembrane domain
|
1271 |
1293 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1345 |
1888 |
5e-238 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000131590
|
| SMART Domains |
Protein: ENSMUSP00000115650
Gene: ENSMUSG00000030123
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:PSI
|
2 |
34 |
1e-13 |
BLAST |
|
IPT
|
35 |
124 |
4.43e-20 |
SMART |
|
Blast:IPT
|
125 |
177 |
3e-30 |
BLAST |
|
Pfam:TIG
|
180 |
233 |
4.6e-6 |
PFAM |
|
| Meta Mutation Damage Score |
0.2482 |
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.2%
- 20x: 92.3%
|
| Validation Efficiency |
98% (99/101) |
| MGI Phenotype |
PHENOTYPE: Homozygous null mice display neonatal lethality, thin-walled atria, and vascular abnormalities including abnormal branchial arch artery development, cardiac outflow tract abnormalities, and reduced vascular smooth muscle around some vessels. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1600012P17Rik |
A |
G |
1: 158,797,094 (GRCm39) |
|
noncoding transcript |
Het |
| Aatk |
G |
A |
11: 119,901,048 (GRCm39) |
T1059M |
probably benign |
Het |
| Adgrg2 |
G |
A |
X: 159,265,347 (GRCm39) |
M532I |
probably benign |
Het |
| Agrn |
GCTCT |
GCTCTCT |
4: 156,250,976 (GRCm39) |
|
probably null |
Het |
| Ahcyl2 |
G |
A |
6: 29,908,354 (GRCm39) |
V575M |
probably damaging |
Het |
| Apobr |
A |
G |
7: 126,185,140 (GRCm39) |
D217G |
probably benign |
Het |
| Aqp9 |
A |
C |
9: 71,019,658 (GRCm39) |
N267K |
probably benign |
Het |
| Arap2 |
A |
G |
5: 62,855,606 (GRCm39) |
V610A |
probably damaging |
Het |
| Arhgap21 |
T |
C |
2: 20,866,015 (GRCm39) |
E893G |
probably damaging |
Het |
| Atn1 |
T |
C |
6: 124,722,259 (GRCm39) |
|
probably benign |
Het |
| Bcl7a |
A |
T |
5: 123,494,032 (GRCm39) |
D68V |
probably damaging |
Het |
| Cbl |
A |
C |
9: 44,075,462 (GRCm39) |
C394W |
probably damaging |
Het |
| Ccdc18 |
T |
A |
5: 108,341,668 (GRCm39) |
D854E |
probably benign |
Het |
| Ccdc93 |
A |
T |
1: 121,426,956 (GRCm39) |
E580V |
probably damaging |
Het |
| Cd180 |
T |
A |
13: 102,842,517 (GRCm39) |
M521K |
probably benign |
Het |
| Cd300ld2 |
T |
G |
11: 114,903,444 (GRCm39) |
|
probably benign |
Het |
| Cdh10 |
T |
C |
15: 18,899,690 (GRCm39) |
F6L |
probably benign |
Het |
| Cep78 |
A |
G |
19: 15,933,368 (GRCm39) |
S737P |
probably damaging |
Het |
| Ces1f |
G |
T |
8: 94,000,893 (GRCm39) |
|
probably benign |
Het |
| Clcn1 |
T |
A |
6: 42,282,475 (GRCm39) |
D442E |
probably damaging |
Het |
| Col20a1 |
T |
C |
2: 180,657,606 (GRCm39) |
L1250P |
possibly damaging |
Het |
| Crispld2 |
G |
A |
8: 120,737,306 (GRCm39) |
G19E |
probably benign |
Het |
| Ctbp2 |
C |
T |
7: 132,592,283 (GRCm39) |
A849T |
probably benign |
Het |
| Cts6 |
A |
G |
13: 61,349,393 (GRCm39) |
I105T |
probably benign |
Het |
| Cul4a |
A |
G |
8: 13,192,589 (GRCm39) |
T617A |
possibly damaging |
Het |
| Cyp2c68 |
G |
T |
19: 39,722,733 (GRCm39) |
R272S |
probably benign |
Het |
| Cystm1 |
A |
G |
18: 36,499,729 (GRCm39) |
Y48C |
unknown |
Het |
| Dach1 |
T |
A |
14: 98,077,645 (GRCm39) |
R579S |
possibly damaging |
Het |
| Ddrgk1 |
A |
T |
2: 130,496,215 (GRCm39) |
I270N |
probably damaging |
Het |
| Dhx32 |
A |
T |
7: 133,339,025 (GRCm39) |
C197S |
probably benign |
Het |
| Dnah10 |
A |
C |
5: 124,909,590 (GRCm39) |
|
probably null |
Het |
| Ecm2 |
T |
C |
13: 49,683,621 (GRCm39) |
V533A |
probably benign |
Het |
| Eif4g1 |
A |
G |
16: 20,497,398 (GRCm39) |
T202A |
probably damaging |
Het |
| Ephb4 |
A |
T |
5: 137,361,572 (GRCm39) |
Q525L |
possibly damaging |
Het |
| F2 |
T |
C |
2: 91,465,539 (GRCm39) |
D82G |
probably benign |
Het |
| Fam184b |
G |
T |
5: 45,689,231 (GRCm39) |
N868K |
possibly damaging |
Het |
| Fbxo25 |
A |
G |
8: 13,985,248 (GRCm39) |
T314A |
probably damaging |
Het |
| Folh1 |
A |
G |
7: 86,375,114 (GRCm39) |
M624T |
possibly damaging |
Het |
| Gabra5 |
G |
A |
7: 57,138,940 (GRCm39) |
R71* |
probably null |
Het |
| Gmpr |
G |
T |
13: 45,696,101 (GRCm39) |
V278F |
probably damaging |
Het |
| Hmcn1 |
A |
T |
1: 150,479,563 (GRCm39) |
C4634S |
probably damaging |
Het |
| Hspa5 |
T |
C |
2: 34,664,553 (GRCm39) |
F336L |
probably damaging |
Het |
| Igfbp4 |
G |
A |
11: 98,932,512 (GRCm39) |
G64R |
probably damaging |
Het |
| Itch |
G |
A |
2: 155,010,666 (GRCm39) |
V45I |
probably damaging |
Het |
| Itgb1 |
T |
A |
8: 129,446,938 (GRCm39) |
F484L |
probably benign |
Het |
| Itpr3 |
A |
G |
17: 27,338,997 (GRCm39) |
I2593V |
probably benign |
Het |
| Kcnj8 |
T |
A |
6: 142,515,966 (GRCm39) |
H47L |
probably damaging |
Het |
| Lcn2 |
T |
C |
2: 32,275,434 (GRCm39) |
T194A |
possibly damaging |
Het |
| Mast4 |
A |
T |
13: 102,930,625 (GRCm39) |
V209D |
probably damaging |
Het |
| Matn3 |
T |
A |
12: 9,002,041 (GRCm39) |
D84E |
probably damaging |
Het |
| Mcm7 |
T |
A |
5: 138,168,637 (GRCm39) |
Q18L |
possibly damaging |
Het |
| Mctp1 |
G |
A |
13: 76,533,267 (GRCm39) |
C205Y |
possibly damaging |
Het |
| Megf11 |
A |
G |
9: 64,587,581 (GRCm39) |
T460A |
probably benign |
Het |
| Mlh1 |
A |
T |
9: 111,086,092 (GRCm39) |
|
probably benign |
Het |
| Mylk |
T |
A |
16: 34,732,600 (GRCm39) |
S627T |
probably benign |
Het |
| Nat2 |
A |
G |
8: 67,954,204 (GRCm39) |
M105V |
possibly damaging |
Het |
| Nav2 |
A |
G |
7: 49,197,943 (GRCm39) |
T2A |
possibly damaging |
Het |
| Ndst3 |
A |
T |
3: 123,465,120 (GRCm39) |
I284N |
probably damaging |
Het |
| Nfix |
A |
G |
8: 85,498,904 (GRCm39) |
V23A |
possibly damaging |
Het |
| Nr2f1 |
T |
C |
13: 78,338,045 (GRCm39) |
Y200C |
probably damaging |
Het |
| Or14a258 |
T |
C |
7: 86,035,769 (GRCm39) |
Y33C |
probably damaging |
Het |
| Or2g25 |
T |
C |
17: 37,970,754 (GRCm39) |
I157V |
possibly damaging |
Het |
| Or6b13 |
G |
A |
7: 139,782,285 (GRCm39) |
R133C |
probably damaging |
Het |
| Or8d1b |
T |
C |
9: 38,887,200 (GRCm39) |
V76A |
probably benign |
Het |
| Or8u8 |
T |
G |
2: 86,011,882 (GRCm39) |
D191A |
probably damaging |
Het |
| Pcdhb21 |
T |
C |
18: 37,647,648 (GRCm39) |
V259A |
possibly damaging |
Het |
| Phip |
A |
T |
9: 82,827,845 (GRCm39) |
V127E |
probably damaging |
Het |
| Pik3r5 |
A |
G |
11: 68,383,318 (GRCm39) |
D379G |
probably damaging |
Het |
| Pkdrej |
A |
T |
15: 85,704,525 (GRCm39) |
C470* |
probably null |
Het |
| Polr1a |
G |
A |
6: 71,943,508 (GRCm39) |
V1248I |
probably damaging |
Het |
| Pou3f2 |
A |
T |
4: 22,486,917 (GRCm39) |
C405* |
probably null |
Het |
| Ppp1r3a |
A |
T |
6: 14,718,404 (GRCm39) |
S837T |
probably damaging |
Het |
| Rest |
T |
A |
5: 77,428,745 (GRCm39) |
V388E |
probably damaging |
Het |
| Rnft2 |
A |
T |
5: 118,370,540 (GRCm39) |
W220R |
probably damaging |
Het |
| Rnpc3 |
A |
T |
3: 113,415,559 (GRCm39) |
Y107* |
probably null |
Het |
| Senp8 |
G |
A |
9: 59,644,835 (GRCm39) |
S94F |
probably damaging |
Het |
| Ski |
A |
G |
4: 155,306,698 (GRCm39) |
S94P |
possibly damaging |
Het |
| Skint8 |
A |
G |
4: 111,794,192 (GRCm39) |
D194G |
probably damaging |
Het |
| Slc35c2 |
C |
A |
2: 165,120,303 (GRCm39) |
R232L |
probably benign |
Het |
| Slc43a3 |
T |
A |
2: 84,777,245 (GRCm39) |
V198D |
possibly damaging |
Het |
| Slc8b1 |
A |
T |
5: 120,667,717 (GRCm39) |
N467I |
probably damaging |
Het |
| Srbd1 |
A |
G |
17: 86,422,732 (GRCm39) |
|
probably benign |
Het |
| Sstr3 |
T |
C |
15: 78,424,168 (GRCm39) |
H193R |
probably damaging |
Het |
| Sv2c |
A |
C |
13: 96,113,283 (GRCm39) |
S555R |
probably benign |
Het |
| Tagln3 |
A |
G |
16: 45,532,013 (GRCm39) |
V173A |
possibly damaging |
Het |
| Tctn2 |
C |
A |
5: 124,757,143 (GRCm39) |
|
noncoding transcript |
Het |
| Tfap2a |
G |
T |
13: 40,881,884 (GRCm39) |
H167Q |
probably damaging |
Het |
| Tmem213 |
A |
G |
6: 38,086,487 (GRCm39) |
T48A |
possibly damaging |
Het |
| Tmem30c |
A |
G |
16: 57,090,352 (GRCm39) |
|
probably benign |
Het |
| Tmem37 |
A |
G |
1: 119,995,952 (GRCm39) |
S42P |
probably damaging |
Het |
| Tnxb |
C |
T |
17: 34,922,431 (GRCm39) |
Q2415* |
probably null |
Het |
| Ttyh1 |
T |
C |
7: 4,122,730 (GRCm39) |
L26P |
probably damaging |
Het |
| Ubn2 |
T |
A |
6: 38,417,425 (GRCm39) |
D154E |
possibly damaging |
Het |
| Vdac3 |
A |
T |
8: 23,070,553 (GRCm39) |
Y119* |
probably null |
Het |
| Vmn2r58 |
T |
C |
7: 41,486,682 (GRCm39) |
I738V |
possibly damaging |
Het |
| Zfp704 |
A |
G |
3: 9,539,551 (GRCm39) |
|
probably benign |
Het |
| Znfx1 |
G |
A |
2: 166,880,729 (GRCm39) |
R352W |
probably damaging |
Het |
|
| Other mutations in Plxnd1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00764:Plxnd1
|
APN |
6 |
115,944,933 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01099:Plxnd1
|
APN |
6 |
115,946,906 (GRCm39) |
missense |
probably benign |
|
|
IGL01323:Plxnd1
|
APN |
6 |
115,943,760 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL01382:Plxnd1
|
APN |
6 |
115,937,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01786:Plxnd1
|
APN |
6 |
115,936,896 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02244:Plxnd1
|
APN |
6 |
115,955,218 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02272:Plxnd1
|
APN |
6 |
115,970,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02293:Plxnd1
|
APN |
6 |
115,940,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02465:Plxnd1
|
APN |
6 |
115,932,703 (GRCm39) |
makesense |
probably null |
|
|
IGL02873:Plxnd1
|
APN |
6 |
115,936,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03209:Plxnd1
|
APN |
6 |
115,939,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Hiss
|
UTSW |
6 |
115,946,890 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
murmer
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
mutter
|
UTSW |
6 |
115,945,005 (GRCm39) |
missense |
probably benign |
0.27 |
|
rattle
|
UTSW |
6 |
115,936,755 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0238:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0238:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0239:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0239:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0357:Plxnd1
|
UTSW |
6 |
115,946,421 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0646:Plxnd1
|
UTSW |
6 |
115,935,660 (GRCm39) |
splice site |
probably benign |
|
|
R0648:Plxnd1
|
UTSW |
6 |
115,970,962 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0718:Plxnd1
|
UTSW |
6 |
115,943,599 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1116:Plxnd1
|
UTSW |
6 |
115,943,966 (GRCm39) |
splice site |
probably null |
|
|
R1292:Plxnd1
|
UTSW |
6 |
115,939,644 (GRCm39) |
unclassified |
probably benign |
|
|
R1715:Plxnd1
|
UTSW |
6 |
115,945,642 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1760:Plxnd1
|
UTSW |
6 |
115,944,740 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1799:Plxnd1
|
UTSW |
6 |
115,971,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1817:Plxnd1
|
UTSW |
6 |
115,957,562 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1848:Plxnd1
|
UTSW |
6 |
115,943,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1851:Plxnd1
|
UTSW |
6 |
115,940,875 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1864:Plxnd1
|
UTSW |
6 |
115,946,402 (GRCm39) |
splice site |
probably null |
|
|
R1875:Plxnd1
|
UTSW |
6 |
115,955,045 (GRCm39) |
splice site |
probably null |
|
|
R1899:Plxnd1
|
UTSW |
6 |
115,946,324 (GRCm39) |
missense |
probably benign |
|
|
R1913:Plxnd1
|
UTSW |
6 |
115,954,978 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1970:Plxnd1
|
UTSW |
6 |
115,939,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2007:Plxnd1
|
UTSW |
6 |
115,944,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2134:Plxnd1
|
UTSW |
6 |
115,934,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2202:Plxnd1
|
UTSW |
6 |
115,939,725 (GRCm39) |
missense |
probably benign |
0.45 |
|
R2230:Plxnd1
|
UTSW |
6 |
115,941,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2267:Plxnd1
|
UTSW |
6 |
115,939,704 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2427:Plxnd1
|
UTSW |
6 |
115,944,709 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4108:Plxnd1
|
UTSW |
6 |
115,936,276 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4233:Plxnd1
|
UTSW |
6 |
115,942,914 (GRCm39) |
missense |
probably benign |
0.30 |
|
R4280:Plxnd1
|
UTSW |
6 |
115,933,056 (GRCm39) |
splice site |
probably null |
|
|
R4280:Plxnd1
|
UTSW |
6 |
115,933,055 (GRCm39) |
splice site |
probably benign |
|
|
R4346:Plxnd1
|
UTSW |
6 |
115,954,941 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4439:Plxnd1
|
UTSW |
6 |
115,970,937 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4572:Plxnd1
|
UTSW |
6 |
115,932,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4576:Plxnd1
|
UTSW |
6 |
115,945,005 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4599:Plxnd1
|
UTSW |
6 |
115,971,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4614:Plxnd1
|
UTSW |
6 |
115,949,486 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4700:Plxnd1
|
UTSW |
6 |
115,935,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4705:Plxnd1
|
UTSW |
6 |
115,935,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4806:Plxnd1
|
UTSW |
6 |
115,937,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4944:Plxnd1
|
UTSW |
6 |
115,932,726 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4977:Plxnd1
|
UTSW |
6 |
115,971,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5069:Plxnd1
|
UTSW |
6 |
115,942,862 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5155:Plxnd1
|
UTSW |
6 |
115,935,949 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5460:Plxnd1
|
UTSW |
6 |
115,934,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5729:Plxnd1
|
UTSW |
6 |
115,942,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5909:Plxnd1
|
UTSW |
6 |
115,945,649 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5992:Plxnd1
|
UTSW |
6 |
115,944,748 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6129:Plxnd1
|
UTSW |
6 |
115,955,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6254:Plxnd1
|
UTSW |
6 |
115,954,921 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6273:Plxnd1
|
UTSW |
6 |
115,955,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6310:Plxnd1
|
UTSW |
6 |
115,953,697 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6732:Plxnd1
|
UTSW |
6 |
115,946,890 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6857:Plxnd1
|
UTSW |
6 |
115,970,724 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7243:Plxnd1
|
UTSW |
6 |
115,949,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7282:Plxnd1
|
UTSW |
6 |
115,937,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7632:Plxnd1
|
UTSW |
6 |
115,953,600 (GRCm39) |
missense |
probably benign |
|
|
R7699:Plxnd1
|
UTSW |
6 |
115,936,755 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7915:Plxnd1
|
UTSW |
6 |
115,943,879 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8090:Plxnd1
|
UTSW |
6 |
115,933,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8382:Plxnd1
|
UTSW |
6 |
115,949,433 (GRCm39) |
missense |
probably benign |
|
|
R8507:Plxnd1
|
UTSW |
6 |
115,943,866 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8539:Plxnd1
|
UTSW |
6 |
115,939,768 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8548:Plxnd1
|
UTSW |
6 |
115,934,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8963:Plxnd1
|
UTSW |
6 |
115,949,506 (GRCm39) |
nonsense |
probably null |
|
|
R9119:Plxnd1
|
UTSW |
6 |
115,932,832 (GRCm39) |
splice site |
probably benign |
|
|
R9177:Plxnd1
|
UTSW |
6 |
115,943,469 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9182:Plxnd1
|
UTSW |
6 |
115,970,746 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9185:Plxnd1
|
UTSW |
6 |
115,934,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9226:Plxnd1
|
UTSW |
6 |
115,934,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9433:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9449:Plxnd1
|
UTSW |
6 |
115,932,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9451:Plxnd1
|
UTSW |
6 |
115,940,277 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R9599:Plxnd1
|
UTSW |
6 |
115,940,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9627:Plxnd1
|
UTSW |
6 |
115,940,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9644:Plxnd1
|
UTSW |
6 |
115,940,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9672:Plxnd1
|
UTSW |
6 |
115,940,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
X0024:Plxnd1
|
UTSW |
6 |
115,940,271 (GRCm39) |
missense |
probably benign |
0.02 |
|
X0026:Plxnd1
|
UTSW |
6 |
115,943,745 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
Z1088:Plxnd1
|
UTSW |
6 |
115,944,471 (GRCm39) |
missense |
probably benign |
0.02 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTCTGTGCCCCACTAAGAC -3'
(R):5'- AGTAATTCCTCCACATGGGGTC -3'
Sequencing Primer
(F):5'- GTCTGTGCCCCACTAAGACATTAG -3'
(R):5'- TCCCTCCCCATGAGAAGGACTG -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation