Incidental Mutation 'R7088:Rnf123'
| ID |
550019 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rnf123
|
| Ensembl Gene |
ENSMUSG00000041528 |
| Gene Name |
ring finger protein 123 |
| Synonyms |
KPC1 |
| MMRRC Submission |
045182-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.171)
|
| Stock # |
R7088 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
107928869-107957183 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 107935735 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Glutamine
at position 943
(R943Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125745
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047746]
[ENSMUST00000085060]
[ENSMUST00000160249]
[ENSMUST00000160649]
[ENSMUST00000162355]
[ENSMUST00000162753]
[ENSMUST00000178267]
|
| AlphaFold |
Q5XPI3 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000047746
AA Change: R943Q
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000040803
Gene: ENSMUSG00000041528
AA Change: R943Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1047 |
1067 |
N/A |
INTRINSIC |
|
low complexity region
|
1242 |
1251 |
N/A |
INTRINSIC |
|
RING
|
1260 |
1297 |
5.27e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000085060
|
| SMART Domains |
Protein: ENSMUSP00000082137
Gene: ENSMUSG00000032593
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
LRRNT
|
33 |
65 |
2.55e-2 |
SMART |
|
LRR
|
65 |
83 |
6.97e1 |
SMART |
|
LRR_TYP
|
84 |
107 |
1.56e-2 |
SMART |
|
LRR
|
109 |
131 |
2.84e1 |
SMART |
|
LRR
|
132 |
155 |
7.05e-1 |
SMART |
|
LRR
|
156 |
176 |
3.98e1 |
SMART |
|
LRR
|
182 |
206 |
5.56e0 |
SMART |
|
Blast:LRRCT
|
219 |
274 |
8e-23 |
BLAST |
|
IG
|
285 |
372 |
1.59e-6 |
SMART |
|
transmembrane domain
|
383 |
405 |
N/A |
INTRINSIC |
|
low complexity region
|
407 |
422 |
N/A |
INTRINSIC |
|
low complexity region
|
492 |
504 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000125695
Gene: ENSMUSG00000041528
AA Change: R68Q
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
172 |
192 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000160249
AA Change: R937Q
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000124548
Gene: ENSMUSG00000041528
AA Change: R937Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1041 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1236 |
1245 |
N/A |
INTRINSIC |
|
RING
|
1254 |
1291 |
5.27e-4 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000160649
AA Change: R937Q
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000125495
Gene: ENSMUSG00000041528
AA Change: R937Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1041 |
1061 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000162355
AA Change: R943Q
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000125745
Gene: ENSMUSG00000041528
AA Change: R943Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1047 |
1067 |
N/A |
INTRINSIC |
|
low complexity region
|
1242 |
1251 |
N/A |
INTRINSIC |
|
RING
|
1260 |
1297 |
5.27e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162753
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000178267
AA Change: R937Q
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000136953
Gene: ENSMUSG00000041528
AA Change: R937Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1041 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1236 |
1245 |
N/A |
INTRINSIC |
|
RING
|
1254 |
1291 |
5.27e-4 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
99% (77/78) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains a C-terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions, and an N-terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700020L24Rik |
G |
T |
11: 83,331,232 (GRCm39) |
E48* |
probably null |
Het |
| Acaca |
T |
C |
11: 84,169,783 (GRCm39) |
|
probably null |
Het |
| Albfm1 |
T |
A |
5: 90,720,609 (GRCm39) |
L260* |
probably null |
Het |
| Alkbh3 |
A |
G |
2: 93,835,097 (GRCm39) |
S83P |
possibly damaging |
Het |
| Ammecr1l |
T |
C |
18: 31,904,872 (GRCm39) |
S38P |
probably benign |
Het |
| Armc10 |
T |
C |
5: 21,858,390 (GRCm39) |
V145A |
probably damaging |
Het |
| BC048671 |
A |
G |
6: 90,280,222 (GRCm39) |
K46R |
probably null |
Het |
| C2cd3 |
A |
G |
7: 100,065,388 (GRCm39) |
T347A |
|
Het |
| C8b |
G |
T |
4: 104,650,540 (GRCm39) |
E449D |
probably benign |
Het |
| Camk4 |
T |
C |
18: 33,072,584 (GRCm39) |
S46P |
probably benign |
Het |
| Ccdc113 |
G |
A |
8: 96,264,733 (GRCm39) |
R81H |
probably benign |
Het |
| Cd177 |
A |
T |
7: 24,444,558 (GRCm39) |
C674* |
probably null |
Het |
| Cdc6 |
T |
A |
11: 98,810,065 (GRCm39) |
V458D |
probably damaging |
Het |
| Cenpo |
C |
T |
12: 4,265,307 (GRCm39) |
E238K |
probably benign |
Het |
| Ckap2 |
G |
T |
8: 22,659,882 (GRCm39) |
P533Q |
possibly damaging |
Het |
| Cma1 |
T |
A |
14: 56,181,273 (GRCm39) |
H44L |
probably damaging |
Het |
| Cmya5 |
A |
T |
13: 93,228,372 (GRCm39) |
S2239T |
possibly damaging |
Het |
| Cntnap5b |
T |
A |
1: 100,087,802 (GRCm39) |
I141N |
probably damaging |
Het |
| Col6a4 |
T |
A |
9: 105,877,885 (GRCm39) |
T2031S |
possibly damaging |
Het |
| Cplane1 |
C |
T |
15: 8,248,431 (GRCm39) |
T1660M |
probably benign |
Het |
| Cxcr5 |
T |
A |
9: 44,424,683 (GRCm39) |
T325S |
possibly damaging |
Het |
| Dhx32 |
A |
T |
7: 133,344,417 (GRCm39) |
L204Q |
probably damaging |
Het |
| Dse |
A |
G |
10: 34,029,885 (GRCm39) |
Y402H |
probably damaging |
Het |
| Ecpas |
A |
T |
4: 58,849,766 (GRCm39) |
L458I |
possibly damaging |
Het |
| Exoc6 |
G |
T |
19: 37,565,458 (GRCm39) |
C178F |
probably damaging |
Het |
| Fam149a |
A |
G |
8: 45,803,582 (GRCm39) |
V384A |
probably benign |
Het |
| Fcrl5 |
T |
C |
3: 87,365,141 (GRCm39) |
*597Q |
probably null |
Het |
| Fer1l6 |
A |
G |
15: 58,435,899 (GRCm39) |
K431E |
possibly damaging |
Het |
| Fmo3 |
T |
A |
1: 162,796,434 (GRCm39) |
H46L |
probably benign |
Het |
| Gcm2 |
T |
C |
13: 41,256,840 (GRCm39) |
D303G |
probably damaging |
Het |
| Gk2 |
T |
C |
5: 97,603,534 (GRCm39) |
M435V |
probably damaging |
Het |
| Gli1 |
C |
A |
10: 127,171,868 (GRCm39) |
M295I |
probably damaging |
Het |
| Gm11444 |
G |
T |
11: 85,737,862 (GRCm39) |
H109Q |
|
Het |
| Gtpbp1 |
T |
A |
15: 79,603,483 (GRCm39) |
D182E |
|
Het |
| Hnf4g |
A |
T |
3: 3,713,185 (GRCm39) |
|
probably null |
Het |
| Hsf2 |
G |
A |
10: 57,388,188 (GRCm39) |
R483H |
probably damaging |
Het |
| Kcnq4 |
C |
T |
4: 120,561,596 (GRCm39) |
R491H |
probably damaging |
Het |
| Lama3 |
T |
C |
18: 12,715,602 (GRCm39) |
V1686A |
possibly damaging |
Het |
| Larp6 |
A |
G |
9: 60,631,638 (GRCm39) |
K137E |
probably damaging |
Het |
| Mboat1 |
T |
G |
13: 30,379,772 (GRCm39) |
|
probably null |
Het |
| Mdh1 |
T |
C |
11: 21,508,484 (GRCm39) |
Y286C |
probably damaging |
Het |
| Mga |
G |
T |
2: 119,792,417 (GRCm39) |
K2607N |
probably damaging |
Het |
| Morf4l1 |
C |
A |
9: 89,979,433 (GRCm39) |
V183F |
possibly damaging |
Het |
| Mroh4 |
G |
A |
15: 74,497,993 (GRCm39) |
R196W |
probably benign |
Het |
| Muc16 |
C |
A |
9: 18,503,976 (GRCm39) |
M6438I |
probably damaging |
Het |
| Myom3 |
A |
G |
4: 135,530,589 (GRCm39) |
Y1167C |
probably damaging |
Het |
| Neurl3 |
T |
C |
1: 36,308,302 (GRCm39) |
E170G |
possibly damaging |
Het |
| Nsd3 |
T |
C |
8: 26,156,050 (GRCm39) |
I539T |
probably benign |
Het |
| Nup155 |
T |
C |
15: 8,186,177 (GRCm39) |
F1313S |
probably benign |
Het |
| Nxn |
A |
T |
11: 76,153,974 (GRCm39) |
V287E |
possibly damaging |
Het |
| Or4a80 |
G |
A |
2: 89,582,443 (GRCm39) |
T243I |
probably benign |
Het |
| Or7a38 |
A |
C |
10: 78,753,593 (GRCm39) |
L306F |
probably benign |
Het |
| Or8c13 |
C |
A |
9: 38,091,748 (GRCm39) |
V124F |
probably damaging |
Het |
| Pax6 |
A |
G |
2: 105,526,753 (GRCm39) |
N220D |
probably benign |
Het |
| Pcdha11 |
G |
A |
18: 37,138,470 (GRCm39) |
R33H |
probably benign |
Het |
| Pdzd8 |
A |
G |
19: 59,333,389 (GRCm39) |
F211L |
probably damaging |
Het |
| Pear1 |
C |
A |
3: 87,661,945 (GRCm39) |
V477F |
possibly damaging |
Het |
| Pex19 |
GTCTCTTGTCTCCGAAGGTGCTCTTGATGATTTCTCTTGTCTCCGAAGGTGCTCTTGATGATTTC |
GTCTCTTGTCTCCGAAGGTGCTCTTGATGATTTC |
1: 171,956,150 (GRCm39) |
|
probably null |
Het |
| Pidd1 |
A |
T |
7: 141,020,400 (GRCm39) |
V539E |
probably damaging |
Het |
| Ptprg |
A |
T |
14: 12,207,365 (GRCm38) |
I878F |
probably damaging |
Het |
| Rabepk |
T |
C |
2: 34,675,711 (GRCm39) |
T140A |
probably benign |
Het |
| Ranbp2 |
G |
T |
10: 58,299,728 (GRCm39) |
R454L |
probably damaging |
Het |
| Sash1 |
G |
A |
10: 8,605,481 (GRCm39) |
R970* |
probably null |
Het |
| Serpinb2 |
C |
A |
1: 107,452,422 (GRCm39) |
F333L |
probably damaging |
Het |
| Shank3 |
T |
A |
15: 89,387,728 (GRCm39) |
|
probably null |
Het |
| Slc9a2 |
A |
C |
1: 40,765,539 (GRCm39) |
I310L |
probably damaging |
Het |
| Strip2 |
T |
A |
6: 29,920,532 (GRCm39) |
|
probably null |
Het |
| Thoc3 |
T |
C |
13: 54,611,565 (GRCm39) |
T241A |
probably damaging |
Het |
| Tmem139 |
T |
A |
6: 42,240,199 (GRCm39) |
V2E |
probably damaging |
Het |
| Usp24 |
G |
T |
4: 106,244,743 (GRCm39) |
V1233F |
probably damaging |
Het |
| Vnn1 |
A |
G |
10: 23,776,645 (GRCm39) |
Q332R |
probably benign |
Het |
| Wac |
T |
A |
18: 7,921,455 (GRCm39) |
H530Q |
probably damaging |
Het |
| Wdr35 |
T |
A |
12: 9,028,659 (GRCm39) |
N92K |
probably benign |
Het |
| Zbtb18 |
T |
G |
1: 177,274,820 (GRCm39) |
L60R |
probably damaging |
Het |
| Zfp184 |
T |
A |
13: 22,144,162 (GRCm39) |
C623S |
probably damaging |
Het |
| Zfp292 |
A |
G |
4: 34,806,796 (GRCm39) |
Y2088H |
probably damaging |
Het |
| Zfp975 |
G |
T |
7: 42,312,096 (GRCm39) |
S172R |
probably benign |
Het |
| Zswim2 |
G |
A |
2: 83,746,071 (GRCm39) |
Q456* |
probably null |
Het |
|
| Other mutations in Rnf123 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00950:Rnf123
|
APN |
9 |
107,944,594 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01358:Rnf123
|
APN |
9 |
107,946,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01464:Rnf123
|
APN |
9 |
107,929,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01637:Rnf123
|
APN |
9 |
107,935,437 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01669:Rnf123
|
APN |
9 |
107,935,555 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01905:Rnf123
|
APN |
9 |
107,948,569 (GRCm39) |
splice site |
probably benign |
|
|
IGL02070:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02072:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02073:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02074:Rnf123
|
APN |
9 |
107,944,088 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02079:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02080:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02231:Rnf123
|
APN |
9 |
107,943,598 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02281:Rnf123
|
APN |
9 |
107,948,651 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02336:Rnf123
|
APN |
9 |
107,939,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02543:Rnf123
|
APN |
9 |
107,943,547 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02565:Rnf123
|
APN |
9 |
107,929,411 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02571:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02572:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02574:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02586:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02589:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02600:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02601:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02602:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02603:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02609:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02628:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02629:Rnf123
|
APN |
9 |
107,947,988 (GRCm39) |
splice site |
probably benign |
|
|
IGL02629:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02630:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02631:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02632:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02650:Rnf123
|
APN |
9 |
107,946,947 (GRCm39) |
missense |
probably benign |
0.29 |
|
IGL02690:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02691:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02692:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02693:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02713:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02736:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02929:Rnf123
|
APN |
9 |
107,946,275 (GRCm39) |
missense |
probably benign |
|
|
R1175:Rnf123
|
UTSW |
9 |
107,954,572 (GRCm39) |
missense |
probably benign |
|
|
R1465:Rnf123
|
UTSW |
9 |
107,948,665 (GRCm39) |
splice site |
probably benign |
|
|
R1502:Rnf123
|
UTSW |
9 |
107,945,709 (GRCm39) |
splice site |
probably null |
|
|
R1682:Rnf123
|
UTSW |
9 |
107,954,597 (GRCm39) |
missense |
probably benign |
0.16 |
|
R1817:Rnf123
|
UTSW |
9 |
107,940,125 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1855:Rnf123
|
UTSW |
9 |
107,938,990 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2394:Rnf123
|
UTSW |
9 |
107,940,735 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2483:Rnf123
|
UTSW |
9 |
107,940,720 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3896:Rnf123
|
UTSW |
9 |
107,946,302 (GRCm39) |
splice site |
probably benign |
|
|
R3940:Rnf123
|
UTSW |
9 |
107,941,234 (GRCm39) |
splice site |
probably benign |
|
|
R4206:Rnf123
|
UTSW |
9 |
107,941,162 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4641:Rnf123
|
UTSW |
9 |
107,935,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4714:Rnf123
|
UTSW |
9 |
107,929,638 (GRCm39) |
splice site |
probably null |
|
|
R4767:Rnf123
|
UTSW |
9 |
107,929,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4849:Rnf123
|
UTSW |
9 |
107,933,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4899:Rnf123
|
UTSW |
9 |
107,940,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5274:Rnf123
|
UTSW |
9 |
107,941,202 (GRCm39) |
frame shift |
probably null |
|
|
R5275:Rnf123
|
UTSW |
9 |
107,941,202 (GRCm39) |
frame shift |
probably null |
|
|
R5276:Rnf123
|
UTSW |
9 |
107,941,202 (GRCm39) |
frame shift |
probably null |
|
|
R5294:Rnf123
|
UTSW |
9 |
107,941,202 (GRCm39) |
frame shift |
probably null |
|
|
R5295:Rnf123
|
UTSW |
9 |
107,941,202 (GRCm39) |
frame shift |
probably null |
|
|
R5394:Rnf123
|
UTSW |
9 |
107,947,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5717:Rnf123
|
UTSW |
9 |
107,944,623 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6186:Rnf123
|
UTSW |
9 |
107,947,157 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R6449:Rnf123
|
UTSW |
9 |
107,933,252 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6502:Rnf123
|
UTSW |
9 |
107,945,531 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6944:Rnf123
|
UTSW |
9 |
107,940,822 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7003:Rnf123
|
UTSW |
9 |
107,940,882 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7092:Rnf123
|
UTSW |
9 |
107,945,799 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7100:Rnf123
|
UTSW |
9 |
107,933,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7257:Rnf123
|
UTSW |
9 |
107,946,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7453:Rnf123
|
UTSW |
9 |
107,947,607 (GRCm39) |
splice site |
probably null |
|
|
R7468:Rnf123
|
UTSW |
9 |
107,946,208 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7517:Rnf123
|
UTSW |
9 |
107,947,473 (GRCm39) |
nonsense |
probably null |
|
|
R7577:Rnf123
|
UTSW |
9 |
107,947,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8296:Rnf123
|
UTSW |
9 |
107,940,089 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8322:Rnf123
|
UTSW |
9 |
107,945,706 (GRCm39) |
missense |
probably benign |
0.26 |
|
R8754:Rnf123
|
UTSW |
9 |
107,948,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8783:Rnf123
|
UTSW |
9 |
107,946,272 (GRCm39) |
missense |
probably benign |
|
|
R9052:Rnf123
|
UTSW |
9 |
107,936,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9156:Rnf123
|
UTSW |
9 |
107,940,227 (GRCm39) |
splice site |
probably benign |
|
|
R9170:Rnf123
|
UTSW |
9 |
107,948,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9332:Rnf123
|
UTSW |
9 |
107,944,704 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9385:Rnf123
|
UTSW |
9 |
107,929,467 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9394:Rnf123
|
UTSW |
9 |
107,942,905 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9432:Rnf123
|
UTSW |
9 |
107,937,008 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9717:Rnf123
|
UTSW |
9 |
107,954,963 (GRCm39) |
missense |
probably benign |
0.43 |
|
Z1176:Rnf123
|
UTSW |
9 |
107,940,180 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Rnf123
|
UTSW |
9 |
107,935,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCAGGATCCAGTTGGTCTG -3'
(R):5'- GCACTGGTGAGATGTCTTCC -3'
Sequencing Primer
(F):5'- AGTTGGTCTGGGCCCAG -3'
(R):5'- TGGAATGGCCTGTCCCAGAG -3'
|
| Posted On |
2019-05-15 |
Incidental Mutation