Mutagenetix > Incidental Mutation

Incidental Mutation 'R1471:Usp34'

164912

Institutional Source

Beutler Lab

Gene Symbol

Usp34

Ensembl Gene

ENSMUSG00000056342

Gene Name

ubiquitin specific peptidase 34

Synonyms

Murr2, A530081C03Rik

MMRRC Submission

039524-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.732) question?

Stock #

R1471 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

23306895-23490560 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to A at 23488862 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glutamine to Lysine at position 3475 (Q3475K)

Ref Sequence

ENSEMBL: ENSMUSP00000137430 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000020529] [ENSMUST00000109539] [ENSMUST00000128559] [ENSMUST00000129368] [ENSMUST00000147157] [ENSMUST00000180046]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000020529

SMART Domains

Protein: ENSMUSP00000020529
Gene: ENSMUSG00000020288

Domain	Start	End	E-Value	Type
Aha1_N	29	163	2.52e-57	SMART
Pfam:AHSA1	209	325	1.4e-23	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000109539

SMART Domains

Protein: ENSMUSP00000105166
Gene: ENSMUSG00000020288

Domain	Start	End	E-Value	Type
Aha1_N	2	115	2.33e-38	SMART
Pfam:AHSA1	161	277	4.3e-22	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000122864

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000124801

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000125701

Predicted Effect

probably benign
Transcript: ENSMUST00000128372

SMART Domains

Protein: ENSMUSP00000121255
Gene: ENSMUSG00000020288

Domain	Start	End	E-Value	Type
Aha1_N	15	149	2.52e-57	SMART
Pfam:AHSA1	195	311	7.5e-23	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000128559

SMART Domains

Protein: ENSMUSP00000115134
Gene: ENSMUSG00000020288

Domain	Start	End	E-Value	Type
Aha1_N	29	159	1.59e-54	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000129368

SMART Domains

Protein: ENSMUSP00000121426
Gene: ENSMUSG00000056342

Domain	Start	End	E-Value	Type
Blast:Drf_GBD	2	86	1e-19	BLAST
low complexity region	231	244	N/A	INTRINSIC
coiled coil region	259	281	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000137823
AA Change: Q3494K

SMART Domains

Protein: ENSMUSP00000120747
Gene: ENSMUSG00000056342
AA Change: Q3494K

Domain	Start	End	E-Value	Type
low complexity region	489	500	N/A	INTRINSIC
low complexity region	530	544	N/A	INTRINSIC
low complexity region	591	610	N/A	INTRINSIC
coiled coil region	626	671	N/A	INTRINSIC
low complexity region	827	842	N/A	INTRINSIC
low complexity region	1207	1218	N/A	INTRINSIC
low complexity region	1399	1410	N/A	INTRINSIC
low complexity region	1518	1532	N/A	INTRINSIC
low complexity region	1751	1764	N/A	INTRINSIC
low complexity region	1812	1824	N/A	INTRINSIC
Pfam:UCH	1950	2293	7.6e-44	PFAM
Pfam:UCH_1	1951	2249	3.6e-22	PFAM
low complexity region	2542	2564	N/A	INTRINSIC
low complexity region	2672	2679	N/A	INTRINSIC
Blast:Drf_GBD	2943	3116	3e-53	BLAST
low complexity region	3344	3357	N/A	INTRINSIC
coiled coil region	3371	3393	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000147157

SMART Domains

Protein: ENSMUSP00000121920
Gene: ENSMUSG00000020288

Domain	Start	End	E-Value	Type
Aha1_N	29	138	4.15e-26	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000153409

Predicted Effect

probably benign
Transcript: ENSMUST00000180046
AA Change: Q3475K

PolyPhen 2 Score 0.196 (Sensitivity: 0.92; Specificity: 0.87)

SMART Domains

Protein: ENSMUSP00000137430
Gene: ENSMUSG00000056342
AA Change: Q3475K

Domain	Start	End	E-Value	Type
low complexity region	469	480	N/A	INTRINSIC
low complexity region	510	524	N/A	INTRINSIC
low complexity region	571	590	N/A	INTRINSIC
coiled coil region	607	652	N/A	INTRINSIC
low complexity region	807	822	N/A	INTRINSIC
low complexity region	1187	1198	N/A	INTRINSIC
low complexity region	1379	1390	N/A	INTRINSIC
low complexity region	1498	1512	N/A	INTRINSIC
low complexity region	1731	1744	N/A	INTRINSIC
low complexity region	1792	1804	N/A	INTRINSIC
Pfam:UCH	1930	2273	2.3e-44	PFAM
Pfam:UCH_1	1931	2229	1.1e-22	PFAM
low complexity region	2522	2544	N/A	INTRINSIC
low complexity region	2652	2659	N/A	INTRINSIC
Blast:Drf_GBD	2923	3096	2e-53	BLAST
low complexity region	3324	3337	N/A	INTRINSIC
coiled coil region	3352	3374	N/A	INTRINSIC

Coding Region Coverage

1x: 99.3%
3x: 98.6%
10x: 96.8%
20x: 94.4%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 96 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
0610010F05Rik	A	T	11: 23,615,222 (GRCm38)	M255K	probably damaging	Het
4930486L24Rik	C	A	13: 60,853,522 (GRCm38)	K130N	probably damaging	Het
Adam6a	T	A	12: 113,544,393 (GRCm38)	S129T	probably damaging	Het
Adamts10	T	A	17: 33,553,138 (GRCm38)	F1087I	probably damaging	Het
Afp	T	A	5: 90,503,682 (GRCm38)	N385K	possibly damaging	Het
Ahnak	T	G	19: 9,012,932 (GRCm38)		probably benign	Het
Akap6	A	G	12: 53,141,496 (GRCm38)	T1898A	probably benign	Het
Antxr2	C	A	5: 97,975,340 (GRCm38)	V283F	possibly damaging	Het
Asgr1	T	C	11: 70,056,093 (GRCm38)	V55A	possibly damaging	Het
Asxl3	A	G	18: 22,516,354 (GRCm38)	K467E	probably damaging	Het
Atp5a1	C	A	18: 77,781,269 (GRCm38)	Q398K	probably damaging	Het
Atxn2	T	A	5: 121,786,374 (GRCm38)	D455E	probably damaging	Het
B4galt6	C	T	18: 20,745,353 (GRCm38)	A39T	possibly damaging	Het
C130073F10Rik	C	T	4: 101,890,338 (GRCm38)	E165K	probably benign	Het
Cabin1	A	G	10: 75,694,792 (GRCm38)	C1519R	probably damaging	Het
Casp8ap2	C	T	4: 32,639,386 (GRCm38)	R147*	probably null	Het
Ccdc88b	A	G	19: 6,854,023 (GRCm38)	L517P	probably benign	Het
Cd109	G	A	9: 78,654,587 (GRCm38)	V220I	probably damaging	Het
Cd2ap	T	C	17: 42,820,597 (GRCm38)	K369R	probably benign	Het
Cd300c	A	G	11: 114,959,788 (GRCm38)	V63A	probably benign	Het
Cnot10	A	G	9: 114,591,551 (GRCm38)	V741A	probably benign	Het
Col18a1	G	T	10: 77,096,206 (GRCm38)	Q350K	unknown	Het
Crnkl1	T	C	2: 145,932,316 (GRCm38)	K76E	possibly damaging	Het
Cryzl2	A	G	1: 157,470,721 (GRCm38)	K227E	probably benign	Het
Cts6	G	A	13: 61,196,380 (GRCm38)	T286I	probably benign	Het
Cul1	T	C	6: 47,514,886 (GRCm38)	V392A	probably damaging	Het
Dcaf7	T	A	11: 106,046,747 (GRCm38)	F65L	probably benign	Het
Dgke	A	C	11: 89,055,494 (GRCm38)	V160G	possibly damaging	Het
Dock8	C	A	19: 25,201,036 (GRCm38)	Q2098K	possibly damaging	Het
Efhb	T	A	17: 53,399,112 (GRCm38)	D799V	possibly damaging	Het
Ephb2	T	C	4: 136,658,951 (GRCm38)	D829G	probably benign	Het
Exosc1	A	T	19: 41,924,718 (GRCm38)	S117R	probably damaging	Het
Fga	T	C	3: 83,028,618 (GRCm38)	S51P	probably benign	Het
Fmn1	T	C	2: 113,693,094 (GRCm38)	F1141L	possibly damaging	Het
Foxm1	C	T	6: 128,373,874 (GRCm38)	L713F	probably damaging	Het
Galnt4	A	G	10: 99,108,674 (GRCm38)	E87G	probably benign	Het
Gamt	T	C	10: 80,260,858 (GRCm38)	D15G	probably benign	Het
Gm13101	T	C	4: 143,964,953 (GRCm38)	N400S	probably benign	Het
Gm15557	C	A	2: 155,942,254 (GRCm38)	D154E	possibly damaging	Het
Gnptab	A	G	10: 88,445,763 (GRCm38)	I1211V	probably benign	Het
Greb1	A	T	12: 16,711,774 (GRCm38)	M535K	probably damaging	Het
Grm8	C	A	6: 27,363,309 (GRCm38)	A736S	possibly damaging	Het
Hspa14	T	C	2: 3,491,608 (GRCm38)	I373M	probably benign	Het
Ifi207	T	A	1: 173,730,063 (GRCm38)	T370S	unknown	Het
Igf1r	A	G	7: 68,003,837 (GRCm38)	N41S	probably damaging	Het
Ikzf5	A	T	7: 131,391,767 (GRCm38)	V224D	probably damaging	Het
Il10	C	A	1: 131,021,373 (GRCm38)	Y90*	probably null	Het
Itga4	A	G	2: 79,287,032 (GRCm38)	D394G	probably benign	Het
Kif21a	A	T	15: 90,956,419 (GRCm38)	S1165T	probably benign	Het
Krtap14	A	G	16: 88,825,627 (GRCm38)	S155P	probably damaging	Het
Loxl2	A	G	14: 69,693,097 (GRCm38)	N770S	probably benign	Het
Man2b1	A	G	8: 85,086,845 (GRCm38)	D222G	probably damaging	Het
Mcub	T	A	3: 129,915,815 (GRCm38)	Y283F	probably damaging	Het
Meis3	T	A	7: 16,177,571 (GRCm38)	Y64*	probably null	Het
Mfsd6	T	A	1: 52,709,557 (GRCm38)	I50F	probably benign	Het
Micu2	T	C	14: 57,945,397 (GRCm38)	T165A	probably damaging	Het
Mtcl1	T	C	17: 66,379,148 (GRCm38)	E921G	probably damaging	Het
Muc5b	A	T	7: 141,843,234 (GRCm38)	N215Y	unknown	Het
Muc6	A	G	7: 141,647,909 (GRCm38)	F772L	possibly damaging	Het
Myt1	A	G	2: 181,797,111 (GRCm38)	D142G	probably benign	Het
Nol6	C	T	4: 41,120,281 (GRCm38)	V479I	probably benign	Het
Nsun7	A	G	5: 66,284,229 (GRCm38)	K414E	probably benign	Het
Nup210l	A	C	3: 90,170,562 (GRCm38)	I914L	probably benign	Het
Obox3	G	A	7: 15,626,950 (GRCm38)	P88L	probably benign	Het
Olfr1098	C	T	2: 86,922,578 (GRCm38)		probably null	Het
Olfr1122	A	G	2: 87,388,518 (GRCm38)	Y271C	probably damaging	Het
Olfr1132	T	C	2: 87,635,670 (GRCm38)	T26A	probably benign	Het
Olfr1289	T	C	2: 111,484,006 (GRCm38)	L192P	probably damaging	Het
Pclo	T	C	5: 14,680,427 (GRCm38)		probably benign	Het
Pcsk5	T	C	19: 17,568,324 (GRCm38)	N745D	probably damaging	Het
Pdzrn3	T	A	6: 101,151,512 (GRCm38)	N731I	possibly damaging	Het
Pkdrej	T	A	15: 85,817,133 (GRCm38)	Q1534L	probably benign	Het
Rell1	T	A	5: 63,936,085 (GRCm38)	D109V	probably damaging	Het
Rplp0	C	T	5: 115,563,344 (GRCm38)	T285I	probably damaging	Het
Sema3g	C	T	14: 31,228,045 (GRCm38)	R728C	probably damaging	Het
Slc15a2	A	G	16: 36,753,791 (GRCm38)	Y536H	probably damaging	Het
Slc26a5	T	A	5: 21,816,964 (GRCm38)	Y488F	probably benign	Het
Slc5a4a	A	T	10: 76,186,528 (GRCm38)	S566C	probably damaging	Het
Spink7	C	T	18: 62,596,204 (GRCm38)	E21K	possibly damaging	Het
Src	C	T	2: 157,457,187 (GRCm38)	Q35*	probably null	Het
Srrm2	T	A	17: 23,820,796 (GRCm38)	V2234E	probably damaging	Het
Stk36	A	T	1: 74,611,155 (GRCm38)	Q282L	probably benign	Het
Tas2r118	T	G	6: 23,969,171 (GRCm38)	E297A	probably damaging	Het
Terf1	A	G	1: 15,842,970 (GRCm38)	Y385C	probably damaging	Het
Tmc3	T	C	7: 83,598,290 (GRCm38)	S198P	probably damaging	Het
Tmprss11b	C	T	5: 86,660,496 (GRCm38)	R407H	possibly damaging	Het
Tspyl4	G	A	10: 34,298,111 (GRCm38)	E200K	probably damaging	Het
Ttc21a	T	C	9: 119,942,641 (GRCm38)	Y169H	probably damaging	Het
Ugt2b36	C	T	5: 87,092,071 (GRCm38)	D152N	probably damaging	Het
Unk	T	C	11: 116,049,409 (GRCm38)	I196T	probably benign	Het
Uroc1	T	G	6: 90,344,171 (GRCm38)	V243G	probably damaging	Het
Vmn2r117	T	A	17: 23,478,473 (GRCm38)	I82L	probably benign	Het
Vmn2r44	A	T	7: 8,377,883 (GRCm38)	V337E	probably damaging	Het
Zbtb14	C	A	17: 69,388,502 (GRCm38)	F398L	probably damaging	Het
Zfp362	T	C	4: 128,787,200 (GRCm38)	T111A	probably benign	Het
Zfp598	T	C	17: 24,680,072 (GRCm38)	V615A	probably benign	Het

Other mutations in Usp34

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00092:Usp34	APN	11	23,436,020 (GRCm38)	missense	probably damaging	0.98
IGL00477:Usp34	APN	11	23,468,879 (GRCm38)	missense	probably damaging	0.99
IGL01307:Usp34	APN	11	23,417,676 (GRCm38)	missense	probably damaging	0.99
IGL01313:Usp34	APN	11	23,473,206 (GRCm38)	missense	probably damaging	1.00
IGL01794:Usp34	APN	11	23,436,020 (GRCm38)	missense	probably damaging	0.98
IGL01826:Usp34	APN	11	23,436,020 (GRCm38)	missense	probably damaging	0.98
IGL01827:Usp34	APN	11	23,436,020 (GRCm38)	missense	probably damaging	0.98
IGL01830:Usp34	APN	11	23,436,020 (GRCm38)	missense	probably damaging	0.98
IGL01867:Usp34	APN	11	23,384,411 (GRCm38)	missense	possibly damaging	0.77
IGL01939:Usp34	APN	11	23,345,141 (GRCm38)	splice site	probably benign
IGL01977:Usp34	APN	11	23,452,661 (GRCm38)	missense	probably damaging	1.00
IGL01985:Usp34	APN	11	23,452,565 (GRCm38)	missense	probably damaging	1.00
IGL02011:Usp34	APN	11	23,471,554 (GRCm38)	missense	probably damaging	0.99
IGL02302:Usp34	APN	11	23,467,243 (GRCm38)	missense	possibly damaging	0.91
IGL02423:Usp34	APN	11	23,354,900 (GRCm38)	missense	probably benign	0.11
IGL02491:Usp34	APN	11	23,432,630 (GRCm38)	missense	probably damaging	0.98
IGL02532:Usp34	APN	11	23,370,291 (GRCm38)	missense	probably damaging	0.99
IGL02561:Usp34	APN	11	23,351,652 (GRCm38)	missense	probably benign	0.09
IGL02706:Usp34	APN	11	23,388,659 (GRCm38)	splice site	probably benign
IGL02891:Usp34	APN	11	23,487,166 (GRCm38)	missense	probably benign	0.09
IGL03079:Usp34	APN	11	23,432,247 (GRCm38)	missense	possibly damaging	0.48
IGL03089:Usp34	APN	11	23,446,958 (GRCm38)	missense	possibly damaging	0.84
IGL03175:Usp34	APN	11	23,488,686 (GRCm38)	missense	probably benign
IGL03256:Usp34	APN	11	23,420,090 (GRCm38)	nonsense	probably null
IGL03280:Usp34	APN	11	23,354,897 (GRCm38)	missense	probably damaging	1.00
IGL03289:Usp34	APN	11	23,393,818 (GRCm38)	missense	possibly damaging	0.94
IGL03408:Usp34	APN	11	23,446,957 (GRCm38)	missense	possibly damaging	0.92
Chub	UTSW	11	23,464,686 (GRCm38)	missense	probably damaging	0.99
Cicione	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R5571_Usp34_680	UTSW	11	23,457,975 (GRCm38)	missense	probably damaging	0.99
R5713_Usp34_003	UTSW	11	23,343,515 (GRCm38)	missense	possibly damaging	0.94
Roebuck	UTSW	11	23,486,810 (GRCm38)	splice site	probably benign
stoat	UTSW	11	23,487,203 (GRCm38)	missense
tunnelvision	UTSW	11	23,446,968 (GRCm38)	missense
I2288:Usp34	UTSW	11	23,432,473 (GRCm38)	splice site	probably benign
R0047:Usp34	UTSW	11	23,464,403 (GRCm38)	missense	probably benign	0.34
R0047:Usp34	UTSW	11	23,464,403 (GRCm38)	missense	probably benign	0.34
R0099:Usp34	UTSW	11	23,363,111 (GRCm38)	missense	probably damaging	1.00
R0240:Usp34	UTSW	11	23,433,206 (GRCm38)	missense	probably damaging	0.99
R0240:Usp34	UTSW	11	23,433,206 (GRCm38)	missense	probably damaging	0.99
R0403:Usp34	UTSW	11	23,333,838 (GRCm38)	missense	possibly damaging	0.82
R0432:Usp34	UTSW	11	23,401,505 (GRCm38)	missense	probably damaging	0.99
R0446:Usp34	UTSW	11	23,467,207 (GRCm38)	missense	probably damaging	0.97
R0455:Usp34	UTSW	11	23,446,741 (GRCm38)	splice site	probably benign
R0470:Usp34	UTSW	11	23,436,001 (GRCm38)	missense	possibly damaging	0.94
R0472:Usp34	UTSW	11	23,384,509 (GRCm38)	splice site	probably benign
R0512:Usp34	UTSW	11	23,451,997 (GRCm38)	missense	probably benign	0.04
R0557:Usp34	UTSW	11	23,403,848 (GRCm38)	missense	probably damaging	0.98
R0562:Usp34	UTSW	11	23,432,406 (GRCm38)	splice site	probably benign
R0656:Usp34	UTSW	11	23,472,967 (GRCm38)	missense	probably damaging	0.99
R0693:Usp34	UTSW	11	23,452,637 (GRCm38)	missense	probably damaging	0.97
R0739:Usp34	UTSW	11	23,467,243 (GRCm38)	missense	possibly damaging	0.91
R1061:Usp34	UTSW	11	23,384,420 (GRCm38)	missense	possibly damaging	0.51
R1078:Usp34	UTSW	11	23,433,175 (GRCm38)	splice site	probably benign
R1223:Usp34	UTSW	11	23,446,464 (GRCm38)	splice site	probably null
R1295:Usp34	UTSW	11	23,384,477 (GRCm38)	missense	probably damaging	1.00
R1430:Usp34	UTSW	11	23,459,151 (GRCm38)	missense	probably damaging	0.97
R1445:Usp34	UTSW	11	23,351,629 (GRCm38)	missense	probably damaging	0.99
R1468:Usp34	UTSW	11	23,441,171 (GRCm38)	missense	probably damaging	1.00
R1468:Usp34	UTSW	11	23,441,171 (GRCm38)	missense	probably damaging	1.00
R1475:Usp34	UTSW	11	23,473,253 (GRCm38)	missense	probably damaging	0.99
R1628:Usp34	UTSW	11	23,488,725 (GRCm38)	missense	probably damaging	1.00
R1631:Usp34	UTSW	11	23,460,651 (GRCm38)	missense	probably damaging	0.99
R1655:Usp34	UTSW	11	23,375,051 (GRCm38)	missense	probably benign	0.05
R1741:Usp34	UTSW	11	23,364,103 (GRCm38)	missense	probably benign	0.00
R1854:Usp34	UTSW	11	23,426,153 (GRCm38)	missense	probably benign	0.24
R1867:Usp34	UTSW	11	23,361,593 (GRCm38)	missense	possibly damaging	0.82
R1869:Usp34	UTSW	11	23,364,479 (GRCm38)	missense	probably benign	0.37
R1870:Usp34	UTSW	11	23,364,479 (GRCm38)	missense	probably benign	0.37
R1871:Usp34	UTSW	11	23,364,479 (GRCm38)	missense	probably benign	0.37
R1967:Usp34	UTSW	11	23,364,503 (GRCm38)	missense	probably benign	0.01
R2051:Usp34	UTSW	11	23,464,468 (GRCm38)	missense	probably damaging	0.97
R2132:Usp34	UTSW	11	23,464,556 (GRCm38)	missense	possibly damaging	0.95
R2156:Usp34	UTSW	11	23,382,602 (GRCm38)	missense	probably damaging	0.98
R2205:Usp34	UTSW	11	23,385,147 (GRCm38)	missense	probably damaging	0.97
R2342:Usp34	UTSW	11	23,403,599 (GRCm38)	missense	possibly damaging	0.46
R3431:Usp34	UTSW	11	23,370,466 (GRCm38)	missense	possibly damaging	0.95
R3812:Usp34	UTSW	11	23,464,517 (GRCm38)	missense	possibly damaging	0.94
R3872:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R3873:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R3874:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R3875:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R3925:Usp34	UTSW	11	23,343,640 (GRCm38)	missense	probably benign	0.28
R3972:Usp34	UTSW	11	23,457,803 (GRCm38)	missense	probably damaging	1.00
R4018:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R4042:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R4155:Usp34	UTSW	11	23,417,676 (GRCm38)	missense	probably damaging	0.99
R4197:Usp34	UTSW	11	23,444,189 (GRCm38)	missense	probably damaging	0.98
R4352:Usp34	UTSW	11	23,320,727 (GRCm38)	missense	possibly damaging	0.73
R4379:Usp34	UTSW	11	23,384,499 (GRCm38)	missense	possibly damaging	0.52
R4444:Usp34	UTSW	11	23,435,998 (GRCm38)	missense	probably damaging	0.98
R4475:Usp34	UTSW	11	23,457,975 (GRCm38)	missense	possibly damaging	0.95
R4501:Usp34	UTSW	11	23,401,529 (GRCm38)	missense	probably damaging	1.00
R4527:Usp34	UTSW	11	23,421,257 (GRCm38)	missense	possibly damaging	0.57
R4603:Usp34	UTSW	11	23,464,633 (GRCm38)	missense	probably damaging	0.97
R4612:Usp34	UTSW	11	23,432,268 (GRCm38)	missense	probably damaging	0.99
R4673:Usp34	UTSW	11	23,364,480 (GRCm38)	small deletion	probably benign
R4707:Usp34	UTSW	11	23,487,215 (GRCm38)	missense	probably damaging	1.00
R4736:Usp34	UTSW	11	23,393,749 (GRCm38)	splice site	probably null
R4867:Usp34	UTSW	11	23,451,999 (GRCm38)	missense	probably benign	0.28
R4879:Usp34	UTSW	11	23,373,410 (GRCm38)	missense	possibly damaging	0.94
R4977:Usp34	UTSW	11	23,488,982 (GRCm38)	missense	probably damaging	1.00
R5004:Usp34	UTSW	11	23,464,586 (GRCm38)	missense	probably damaging	1.00
R5057:Usp34	UTSW	11	23,458,086 (GRCm38)	intron	probably benign
R5068:Usp34	UTSW	11	23,460,665 (GRCm38)	missense	possibly damaging	0.94
R5304:Usp34	UTSW	11	23,343,616 (GRCm38)	missense	probably damaging	1.00
R5320:Usp34	UTSW	11	23,333,739 (GRCm38)	missense	probably benign
R5327:Usp34	UTSW	11	23,468,846 (GRCm38)	missense	probably damaging	1.00
R5328:Usp34	UTSW	11	23,488,659 (GRCm38)	missense	probably benign	0.04
R5328:Usp34	UTSW	11	23,464,616 (GRCm38)	missense	probably benign	0.01
R5390:Usp34	UTSW	11	23,444,202 (GRCm38)	critical splice donor site	probably null
R5434:Usp34	UTSW	11	23,412,271 (GRCm38)	missense	probably damaging	0.99
R5523:Usp34	UTSW	11	23,349,198 (GRCm38)	missense	probably benign	0.39
R5567:Usp34	UTSW	11	23,488,336 (GRCm38)	missense	probably damaging	0.97
R5571:Usp34	UTSW	11	23,457,975 (GRCm38)	missense	probably damaging	0.99
R5645:Usp34	UTSW	11	23,375,024 (GRCm38)	missense	possibly damaging	0.86
R5713:Usp34	UTSW	11	23,343,515 (GRCm38)	missense	possibly damaging	0.94
R5719:Usp34	UTSW	11	23,354,846 (GRCm38)	missense	probably benign	0.00
R5813:Usp34	UTSW	11	23,421,340 (GRCm38)	missense	probably benign	0.38
R5921:Usp34	UTSW	11	23,464,686 (GRCm38)	missense	probably damaging	0.99
R5928:Usp34	UTSW	11	23,436,040 (GRCm38)	missense	probably damaging	0.98
R5944:Usp34	UTSW	11	23,363,089 (GRCm38)	missense	probably damaging	1.00
R6198:Usp34	UTSW	11	23,484,127 (GRCm38)	missense	probably damaging	1.00
R6229:Usp34	UTSW	11	23,446,778 (GRCm38)	missense	probably damaging	0.99
R6306:Usp34	UTSW	11	23,412,260 (GRCm38)	missense	possibly damaging	0.94
R6320:Usp34	UTSW	11	23,452,520 (GRCm38)	missense	probably damaging	0.98
R6341:Usp34	UTSW	11	23,381,353 (GRCm38)	missense	probably damaging	0.97
R6374:Usp34	UTSW	11	23,438,914 (GRCm38)	missense	probably damaging	1.00
R6398:Usp34	UTSW	11	23,488,666 (GRCm38)	missense	probably benign
R6438:Usp34	UTSW	11	23,364,266 (GRCm38)	missense	probably benign	0.02
R6668:Usp34	UTSW	11	23,460,659 (GRCm38)	missense	probably damaging	0.97
R6700:Usp34	UTSW	11	23,439,011 (GRCm38)	missense	probably damaging	1.00
R6783:Usp34	UTSW	11	23,412,318 (GRCm38)	missense	probably damaging	1.00
R6821:Usp34	UTSW	11	23,367,491 (GRCm38)	missense	possibly damaging	0.79
R6855:Usp34	UTSW	11	23,452,569 (GRCm38)	missense	possibly damaging	0.94
R6916:Usp34	UTSW	11	23,458,023 (GRCm38)	missense	probably damaging	0.98
R7020:Usp34	UTSW	11	23,393,954 (GRCm38)	missense	probably benign	0.05
R7026:Usp34	UTSW	11	23,361,622 (GRCm38)	missense	probably damaging	1.00
R7085:Usp34	UTSW	11	23,363,097 (GRCm38)	missense
R7101:Usp34	UTSW	11	23,426,183 (GRCm38)	missense
R7168:Usp34	UTSW	11	23,464,585 (GRCm38)	missense
R7192:Usp34	UTSW	11	23,460,571 (GRCm38)	missense
R7264:Usp34	UTSW	11	23,333,566 (GRCm38)	missense	probably benign	0.00
R7325:Usp34	UTSW	11	23,419,052 (GRCm38)	missense
R7343:Usp34	UTSW	11	23,488,868 (GRCm38)	missense
R7358:Usp34	UTSW	11	23,361,683 (GRCm38)	missense	probably damaging	0.99
R7369:Usp34	UTSW	11	23,432,361 (GRCm38)	missense
R7389:Usp34	UTSW	11	23,345,200 (GRCm38)	missense
R7459:Usp34	UTSW	11	23,364,458 (GRCm38)	missense	possibly damaging	0.53
R7517:Usp34	UTSW	11	23,446,968 (GRCm38)	missense
R7729:Usp34	UTSW	11	23,449,268 (GRCm38)	missense
R7777:Usp34	UTSW	11	23,382,638 (GRCm38)	missense
R7810:Usp34	UTSW	11	23,412,314 (GRCm38)	missense
R7836:Usp34	UTSW	11	23,446,614 (GRCm38)	missense
R7862:Usp34	UTSW	11	23,464,718 (GRCm38)	missense
R7993:Usp34	UTSW	11	23,377,622 (GRCm38)	missense
R8050:Usp34	UTSW	11	23,446,787 (GRCm38)	missense
R8054:Usp34	UTSW	11	23,361,295 (GRCm38)	missense
R8239:Usp34	UTSW	11	23,446,750 (GRCm38)	missense
R8266:Usp34	UTSW	11	23,486,810 (GRCm38)	splice site	probably benign
R8347:Usp34	UTSW	11	23,412,345 (GRCm38)	missense
R8409:Usp34	UTSW	11	23,457,811 (GRCm38)	missense
R8692:Usp34	UTSW	11	23,429,325 (GRCm38)	missense
R8694:Usp34	UTSW	11	23,484,161 (GRCm38)	missense
R8734:Usp34	UTSW	11	23,444,184 (GRCm38)	missense
R8806:Usp34	UTSW	11	23,484,143 (GRCm38)	missense
R8914:Usp34	UTSW	11	23,343,604 (GRCm38)	missense
R8987:Usp34	UTSW	11	23,464,267 (GRCm38)	missense
R9013:Usp34	UTSW	11	23,370,302 (GRCm38)	missense
R9108:Usp34	UTSW	11	23,370,528 (GRCm38)	missense
R9264:Usp34	UTSW	11	23,489,064 (GRCm38)	missense
R9301:Usp34	UTSW	11	23,472,951 (GRCm38)	missense
R9375:Usp34	UTSW	11	23,487,203 (GRCm38)	missense
R9385:Usp34	UTSW	11	23,449,223 (GRCm38)	missense
R9500:Usp34	UTSW	11	23,381,337 (GRCm38)	missense	probably damaging	0.99
R9566:Usp34	UTSW	11	23,367,529 (GRCm38)	missense
R9629:Usp34	UTSW	11	23,364,364 (GRCm38)	missense
R9679:Usp34	UTSW	11	23,444,369 (GRCm38)	missense
R9680:Usp34	UTSW	11	23,367,385 (GRCm38)	missense	possibly damaging	0.94
R9686:Usp34	UTSW	11	23,474,351 (GRCm38)	missense
R9752:Usp34	UTSW	11	23,459,182 (GRCm38)	missense	probably benign	0.11
X0023:Usp34	UTSW	11	23,375,028 (GRCm38)	missense	possibly damaging	0.73
X0057:Usp34	UTSW	11	23,457,824 (GRCm38)	missense	possibly damaging	0.86
Z1176:Usp34	UTSW	11	23,473,221 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AGCAACTCCTGTTAAAAGACGGCG -3'
(R):5'- GGGAGGACAAAGCTTGACCATCAC -3'

Sequencing Primer
(F):5'- CACACTGTAGACAGTTGCATTGG -3'
(R):5'- CAGCTTCTCAGATCAGCTAAGTC -3'

Posted On

2014-03-28