Incidental Mutation 'R1781:Umodl1'
| ID |
195332 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Umodl1
|
| Ensembl Gene |
ENSMUSG00000054134 |
| Gene Name |
uromodulin-like 1 |
| Synonyms |
D17Ertd488e |
| MMRRC Submission |
039812-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1781 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
31173614-31229684 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 31187524 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Histidine
at position 196
(R196H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000110202
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066554]
[ENSMUST00000066981]
[ENSMUST00000114555]
|
| AlphaFold |
Q5DID3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066554
AA Change: R196H
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000067443
Gene: ENSMUSG00000054134
AA Change: R196H
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066981
AA Change: R196H
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000065470
Gene: ENSMUSG00000054134
AA Change: R196H
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
8.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
8.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
619 |
632 |
N/A |
INTRINSIC |
|
SEA
|
706 |
821 |
8.88e-2 |
SMART |
|
EGF
|
818 |
859 |
4.26e0 |
SMART |
|
ZP
|
909 |
1152 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1186 |
1208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000114555
AA Change: R196H
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000110202
Gene: ENSMUSG00000054134
AA Change: R196H
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
9.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
9.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000174990
|
| Meta Mutation Damage Score |
0.3871 |
| Coding Region Coverage |
- 1x: 97.3%
- 3x: 96.7%
- 10x: 94.6%
- 20x: 90.1%
|
| Validation Efficiency |
97% (88/91) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl2 |
A |
G |
3: 59,932,117 (GRCm39) |
K211E |
probably damaging |
Het |
| Abca13 |
T |
A |
11: 9,219,194 (GRCm39) |
L376Q |
probably damaging |
Het |
| Abca17 |
T |
C |
17: 24,486,531 (GRCm39) |
T1499A |
possibly damaging |
Het |
| Anks6 |
A |
C |
4: 47,043,639 (GRCm39) |
N363K |
possibly damaging |
Het |
| Apob |
T |
A |
12: 8,059,603 (GRCm39) |
I2695N |
possibly damaging |
Het |
| Arhgef18 |
C |
T |
8: 3,430,495 (GRCm39) |
R123W |
probably damaging |
Het |
| Atg14 |
T |
A |
14: 47,786,607 (GRCm39) |
|
probably null |
Het |
| Atg2a |
A |
T |
19: 6,306,243 (GRCm39) |
I1368F |
probably damaging |
Het |
| Btbd9 |
A |
G |
17: 30,732,567 (GRCm39) |
S373P |
probably damaging |
Het |
| Ccdc83 |
T |
C |
7: 89,899,749 (GRCm39) |
E41G |
probably damaging |
Het |
| Ccnh |
T |
C |
13: 85,354,254 (GRCm39) |
S233P |
possibly damaging |
Het |
| Cdh8 |
T |
C |
8: 99,917,094 (GRCm39) |
|
probably null |
Het |
| Cdh8 |
A |
T |
8: 100,006,290 (GRCm39) |
I99N |
probably damaging |
Het |
| Cdr2 |
G |
A |
7: 120,557,268 (GRCm39) |
P419L |
probably benign |
Het |
| Cds1 |
T |
A |
5: 101,960,416 (GRCm39) |
I289K |
possibly damaging |
Het |
| Cherp |
G |
A |
8: 73,221,615 (GRCm39) |
T394I |
probably damaging |
Het |
| Cyp4f17 |
T |
G |
17: 32,742,993 (GRCm39) |
I222S |
possibly damaging |
Het |
| Dcc |
A |
G |
18: 71,511,788 (GRCm39) |
S856P |
probably benign |
Het |
| Dcp1a |
C |
T |
14: 30,235,032 (GRCm39) |
T221I |
probably benign |
Het |
| Ddx10 |
A |
G |
9: 53,118,845 (GRCm39) |
S475P |
probably damaging |
Het |
| Dennd5b |
G |
T |
6: 148,928,896 (GRCm39) |
A759E |
probably damaging |
Het |
| Disp2 |
G |
A |
2: 118,623,042 (GRCm39) |
G1258D |
probably damaging |
Het |
| Fhdc1 |
A |
T |
3: 84,356,111 (GRCm39) |
D444E |
probably damaging |
Het |
| Fhod1 |
T |
C |
8: 106,074,421 (GRCm39) |
|
probably benign |
Het |
| Gcnt7 |
T |
C |
2: 172,296,800 (GRCm39) |
K8R |
probably benign |
Het |
| Gk5 |
C |
T |
9: 96,015,508 (GRCm39) |
T108I |
possibly damaging |
Het |
| Gm8214 |
C |
A |
1: 183,414,129 (GRCm39) |
|
noncoding transcript |
Het |
| Gnl1 |
A |
T |
17: 36,298,638 (GRCm39) |
I434F |
probably damaging |
Het |
| Golga2 |
T |
C |
2: 32,196,588 (GRCm39) |
Y986H |
probably damaging |
Het |
| Gpr21 |
T |
C |
2: 37,407,550 (GRCm39) |
V32A |
probably benign |
Het |
| Grb14 |
A |
T |
2: 64,805,899 (GRCm39) |
|
probably null |
Het |
| H6pd |
A |
T |
4: 150,080,388 (GRCm39) |
F144L |
probably damaging |
Het |
| Hunk |
A |
G |
16: 90,229,448 (GRCm39) |
Y27C |
probably damaging |
Het |
| Ints7 |
C |
T |
1: 191,328,396 (GRCm39) |
T223M |
possibly damaging |
Het |
| Kcnmb2 |
T |
C |
3: 32,233,152 (GRCm39) |
|
probably null |
Het |
| Lilra6 |
A |
T |
7: 3,918,066 (GRCm39) |
L26H |
probably benign |
Het |
| Mc4r |
A |
T |
18: 66,992,918 (GRCm39) |
V65E |
probably damaging |
Het |
| Mgam |
G |
A |
6: 40,646,797 (GRCm39) |
G708R |
probably damaging |
Het |
| Mllt6 |
A |
G |
11: 97,563,395 (GRCm39) |
D326G |
probably benign |
Het |
| Myo7a |
A |
T |
7: 97,722,331 (GRCm39) |
V1198D |
probably damaging |
Het |
| Nampt |
T |
C |
12: 32,883,037 (GRCm39) |
V74A |
probably damaging |
Het |
| Nlrp4b |
G |
C |
7: 10,449,266 (GRCm39) |
V123L |
probably benign |
Het |
| Ntpcr |
T |
A |
8: 126,472,141 (GRCm39) |
L150Q |
probably damaging |
Het |
| Obscn |
C |
T |
11: 58,997,163 (GRCm39) |
E1513K |
probably damaging |
Het |
| Ola1 |
T |
C |
2: 72,987,099 (GRCm39) |
K178E |
possibly damaging |
Het |
| Opalin |
T |
C |
19: 41,056,070 (GRCm39) |
|
probably null |
Het |
| Or10g6 |
A |
G |
9: 39,934,541 (GRCm39) |
N284S |
probably damaging |
Het |
| Or13a20 |
A |
T |
7: 140,232,419 (GRCm39) |
I176F |
probably damaging |
Het |
| Or2ad1 |
C |
T |
13: 21,326,934 (GRCm39) |
V98I |
probably benign |
Het |
| Or2w2 |
C |
T |
13: 21,757,711 (GRCm39) |
G305D |
probably damaging |
Het |
| Or3a10 |
A |
T |
11: 73,935,786 (GRCm39) |
F105I |
probably damaging |
Het |
| Or51ah3 |
C |
T |
7: 103,209,773 (GRCm39) |
P30S |
probably benign |
Het |
| Or52ae9 |
T |
C |
7: 103,390,028 (GRCm39) |
M140V |
probably benign |
Het |
| Or52e15 |
A |
T |
7: 104,645,315 (GRCm39) |
F265L |
possibly damaging |
Het |
| Or5p62 |
A |
G |
7: 107,771,090 (GRCm39) |
V287A |
probably benign |
Het |
| Or7a35 |
T |
C |
10: 78,853,159 (GRCm39) |
M1T |
probably null |
Het |
| P2ry12 |
A |
G |
3: 59,125,199 (GRCm39) |
F159L |
probably benign |
Het |
| Paqr7 |
T |
C |
4: 134,234,592 (GRCm39) |
|
probably null |
Het |
| Parp1 |
T |
C |
1: 180,415,578 (GRCm39) |
S466P |
probably benign |
Het |
| Parp4 |
T |
A |
14: 56,864,838 (GRCm39) |
|
probably null |
Het |
| Pcdh1 |
T |
C |
18: 38,322,977 (GRCm39) |
D952G |
probably damaging |
Het |
| Pde6c |
T |
C |
19: 38,140,146 (GRCm39) |
S336P |
possibly damaging |
Het |
| Pgk2 |
T |
C |
17: 40,519,398 (GRCm39) |
D10G |
probably benign |
Het |
| Phf20l1 |
A |
G |
15: 66,504,674 (GRCm39) |
T771A |
probably damaging |
Het |
| Pkdrej |
A |
G |
15: 85,705,372 (GRCm39) |
V188A |
possibly damaging |
Het |
| Plekhm1 |
A |
G |
11: 103,285,682 (GRCm39) |
L251P |
probably damaging |
Het |
| Prex2 |
A |
T |
1: 11,270,179 (GRCm39) |
N1288I |
probably benign |
Het |
| Sarnp |
T |
C |
10: 128,669,191 (GRCm39) |
L16P |
probably damaging |
Het |
| Scgb3a2 |
T |
C |
18: 43,900,033 (GRCm39) |
|
probably benign |
Het |
| Scn11a |
A |
T |
9: 119,584,148 (GRCm39) |
I1489N |
probably damaging |
Het |
| Scn3a |
A |
T |
2: 65,302,729 (GRCm39) |
L1239Q |
probably damaging |
Het |
| Shisa9 |
T |
C |
16: 12,085,521 (GRCm39) |
S377P |
probably benign |
Het |
| Slc22a30 |
T |
A |
19: 8,313,136 (GRCm39) |
T550S |
probably damaging |
Het |
| Slc25a11 |
T |
C |
11: 70,535,651 (GRCm39) |
T296A |
probably benign |
Het |
| Slc35f1 |
T |
A |
10: 52,938,532 (GRCm39) |
|
probably null |
Het |
| Slc6a13 |
A |
G |
6: 121,311,811 (GRCm39) |
E396G |
probably damaging |
Het |
| Spata31d1c |
T |
C |
13: 65,183,985 (GRCm39) |
I509T |
probably benign |
Het |
| Srsf9 |
C |
A |
5: 115,465,481 (GRCm39) |
Y9* |
probably null |
Het |
| Tasor2 |
T |
C |
13: 3,634,759 (GRCm39) |
T683A |
possibly damaging |
Het |
| Tbx20 |
T |
C |
9: 24,636,795 (GRCm39) |
I431V |
probably benign |
Het |
| Tespa1 |
G |
A |
10: 130,184,119 (GRCm39) |
G67S |
probably benign |
Het |
| Trhde |
A |
T |
10: 114,424,405 (GRCm39) |
V460E |
possibly damaging |
Het |
| Trip12 |
A |
T |
1: 84,708,342 (GRCm39) |
F1739I |
probably benign |
Het |
| Ugcg |
C |
T |
4: 59,207,798 (GRCm39) |
P46S |
probably benign |
Het |
| Vezf1 |
G |
T |
11: 87,972,447 (GRCm39) |
M269I |
probably benign |
Het |
| Vmn1r35 |
A |
T |
6: 66,656,550 (GRCm39) |
M40K |
probably benign |
Het |
| Vmn1r9 |
G |
T |
6: 57,048,300 (GRCm39) |
C125F |
probably benign |
Het |
| Vmn2r12 |
C |
A |
5: 109,239,594 (GRCm39) |
G323V |
probably benign |
Het |
| Vmn2r79 |
A |
T |
7: 86,651,555 (GRCm39) |
H318L |
probably benign |
Het |
| Zfhx3 |
T |
A |
8: 109,520,167 (GRCm39) |
S430T |
probably benign |
Het |
|
| Other mutations in Umodl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00915:Umodl1
|
APN |
17 |
31,227,724 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL01344:Umodl1
|
APN |
17 |
31,215,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01529:Umodl1
|
APN |
17 |
31,215,233 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01609:Umodl1
|
APN |
17 |
31,217,800 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01625:Umodl1
|
APN |
17 |
31,215,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01877:Umodl1
|
APN |
17 |
31,201,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01977:Umodl1
|
APN |
17 |
31,192,742 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02063:Umodl1
|
APN |
17 |
31,206,888 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL02160:Umodl1
|
APN |
17 |
31,205,091 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02252:Umodl1
|
APN |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02427:Umodl1
|
APN |
17 |
31,187,415 (GRCm39) |
splice site |
probably benign |
|
|
IGL02496:Umodl1
|
APN |
17 |
31,217,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02633:Umodl1
|
APN |
17 |
31,208,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03271:Umodl1
|
APN |
17 |
31,205,473 (GRCm39) |
nonsense |
probably null |
|
|
IGL03392:Umodl1
|
APN |
17 |
31,215,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Disquieting
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
floored
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7231_umodl1_507
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
surprising
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
unsettling
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
G1citation:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
PIT4468001:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0653:Umodl1
|
UTSW |
17 |
31,203,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0831:Umodl1
|
UTSW |
17 |
31,215,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1078:Umodl1
|
UTSW |
17 |
31,178,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1166:Umodl1
|
UTSW |
17 |
31,221,772 (GRCm39) |
splice site |
probably benign |
|
|
R1231:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1459:Umodl1
|
UTSW |
17 |
31,205,478 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1459:Umodl1
|
UTSW |
17 |
31,201,232 (GRCm39) |
splice site |
probably benign |
|
|
R1510:Umodl1
|
UTSW |
17 |
31,178,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1654:Umodl1
|
UTSW |
17 |
31,206,942 (GRCm39) |
missense |
probably benign |
|
|
R1757:Umodl1
|
UTSW |
17 |
31,227,674 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1873:Umodl1
|
UTSW |
17 |
31,201,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1911:Umodl1
|
UTSW |
17 |
31,211,128 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R1917:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1918:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2057:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2058:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2089:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2431:Umodl1
|
UTSW |
17 |
31,211,062 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2903:Umodl1
|
UTSW |
17 |
31,211,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3032:Umodl1
|
UTSW |
17 |
31,208,502 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3956:Umodl1
|
UTSW |
17 |
31,221,837 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3975:Umodl1
|
UTSW |
17 |
31,203,763 (GRCm39) |
nonsense |
probably null |
|
|
R4207:Umodl1
|
UTSW |
17 |
31,178,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4287:Umodl1
|
UTSW |
17 |
31,207,039 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4452:Umodl1
|
UTSW |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4684:Umodl1
|
UTSW |
17 |
31,217,088 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4769:Umodl1
|
UTSW |
17 |
31,202,976 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4887:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4888:Umodl1
|
UTSW |
17 |
31,218,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4978:Umodl1
|
UTSW |
17 |
31,205,055 (GRCm39) |
missense |
probably benign |
|
|
R4993:Umodl1
|
UTSW |
17 |
31,205,459 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5241:Umodl1
|
UTSW |
17 |
31,203,066 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5254:Umodl1
|
UTSW |
17 |
31,199,333 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5454:Umodl1
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5456:Umodl1
|
UTSW |
17 |
31,201,263 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5754:Umodl1
|
UTSW |
17 |
31,213,761 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6189:Umodl1
|
UTSW |
17 |
31,215,256 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6222:Umodl1
|
UTSW |
17 |
31,221,866 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6289:Umodl1
|
UTSW |
17 |
31,201,325 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6432:Umodl1
|
UTSW |
17 |
31,205,121 (GRCm39) |
missense |
probably benign |
0.38 |
|
R6478:Umodl1
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6702:Umodl1
|
UTSW |
17 |
31,205,273 (GRCm39) |
splice site |
probably null |
|
|
R6822:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
R6999:Umodl1
|
UTSW |
17 |
31,218,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7067:Umodl1
|
UTSW |
17 |
31,201,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7123:Umodl1
|
UTSW |
17 |
31,201,318 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7219:Umodl1
|
UTSW |
17 |
31,201,236 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7231:Umodl1
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7234:Umodl1
|
UTSW |
17 |
31,205,595 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7297:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7392:Umodl1
|
UTSW |
17 |
31,201,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7401:Umodl1
|
UTSW |
17 |
31,217,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7461:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7594:Umodl1
|
UTSW |
17 |
31,173,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7613:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7763:Umodl1
|
UTSW |
17 |
31,205,430 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7797:Umodl1
|
UTSW |
17 |
31,178,125 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7832:Umodl1
|
UTSW |
17 |
31,192,666 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7954:Umodl1
|
UTSW |
17 |
31,205,361 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8088:Umodl1
|
UTSW |
17 |
31,192,770 (GRCm39) |
missense |
probably benign |
0.29 |
|
R8111:Umodl1
|
UTSW |
17 |
31,190,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8314:Umodl1
|
UTSW |
17 |
31,203,806 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8826:Umodl1
|
UTSW |
17 |
31,202,958 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9067:Umodl1
|
UTSW |
17 |
31,192,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9091:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9099:Umodl1
|
UTSW |
17 |
31,178,147 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9270:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9341:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9343:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9400:Umodl1
|
UTSW |
17 |
31,215,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9569:Umodl1
|
UTSW |
17 |
31,217,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9615:Umodl1
|
UTSW |
17 |
31,217,152 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9787:Umodl1
|
UTSW |
17 |
31,178,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCAGGCATTTTATGCAGAAGGACG -3'
(R):5'- CTAAGGCCATACTGAGCAGCTCAAG -3'
Sequencing Primer
(F):5'- TTATGCAGAAGGACGATCTCCTG -3'
(R):5'- gaccttgaacttgctttatagcc -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation