Incidental Mutation 'R8962:Zdbf2'
| ID |
682367 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zdbf2
|
| Ensembl Gene |
ENSMUSG00000027520 |
| Gene Name |
zinc finger, DBF-type containing 2 |
| Synonyms |
4930431J08Rik, 9330107J05Rik |
| MMRRC Submission |
068796-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.096)
|
| Stock # |
R8962 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
63312424-63353735 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 63347162 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Aspartic acid
at position 1847
(G1847D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109767
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029025]
[ENSMUST00000114132]
|
| AlphaFold |
Q5SS00 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000029025
AA Change: G1847D
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000029025
Gene: ENSMUSG00000027520
AA Change: G1847D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
79 |
99 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
164 |
N/A |
INTRINSIC |
|
low complexity region
|
378 |
405 |
N/A |
INTRINSIC |
|
internal_repeat_6
|
407 |
565 |
7.68e-5 |
PROSPERO |
|
internal_repeat_5
|
418 |
768 |
5.53e-5 |
PROSPERO |
|
internal_repeat_1
|
618 |
873 |
3.17e-15 |
PROSPERO |
|
internal_repeat_4
|
621 |
885 |
2.09e-6 |
PROSPERO |
|
internal_repeat_3
|
642 |
886 |
1.52e-7 |
PROSPERO |
|
internal_repeat_2
|
650 |
912 |
5.87e-11 |
PROSPERO |
|
internal_repeat_6
|
722 |
891 |
7.68e-5 |
PROSPERO |
|
low complexity region
|
965 |
982 |
N/A |
INTRINSIC |
|
internal_repeat_4
|
1061 |
1328 |
2.09e-6 |
PROSPERO |
|
internal_repeat_2
|
1215 |
1484 |
5.87e-11 |
PROSPERO |
|
internal_repeat_3
|
1287 |
1507 |
1.52e-7 |
PROSPERO |
|
internal_repeat_1
|
1307 |
1536 |
3.17e-15 |
PROSPERO |
|
internal_repeat_5
|
1388 |
1758 |
5.53e-5 |
PROSPERO |
|
low complexity region
|
1767 |
1778 |
N/A |
INTRINSIC |
|
low complexity region
|
2211 |
2235 |
N/A |
INTRINSIC |
|
low complexity region
|
2240 |
2399 |
N/A |
INTRINSIC |
|
low complexity region
|
2402 |
2420 |
N/A |
INTRINSIC |
|
low complexity region
|
2446 |
2458 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114132
AA Change: G1847D
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000109767
Gene: ENSMUSG00000027520
AA Change: G1847D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
79 |
99 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
164 |
N/A |
INTRINSIC |
|
low complexity region
|
378 |
405 |
N/A |
INTRINSIC |
|
internal_repeat_6
|
407 |
565 |
7.68e-5 |
PROSPERO |
|
internal_repeat_5
|
418 |
768 |
5.53e-5 |
PROSPERO |
|
internal_repeat_1
|
618 |
873 |
3.17e-15 |
PROSPERO |
|
internal_repeat_4
|
621 |
885 |
2.09e-6 |
PROSPERO |
|
internal_repeat_3
|
642 |
886 |
1.52e-7 |
PROSPERO |
|
internal_repeat_2
|
650 |
912 |
5.87e-11 |
PROSPERO |
|
internal_repeat_6
|
722 |
891 |
7.68e-5 |
PROSPERO |
|
low complexity region
|
965 |
982 |
N/A |
INTRINSIC |
|
internal_repeat_4
|
1061 |
1328 |
2.09e-6 |
PROSPERO |
|
internal_repeat_2
|
1215 |
1484 |
5.87e-11 |
PROSPERO |
|
internal_repeat_3
|
1287 |
1507 |
1.52e-7 |
PROSPERO |
|
internal_repeat_1
|
1307 |
1536 |
3.17e-15 |
PROSPERO |
|
internal_repeat_5
|
1388 |
1758 |
5.53e-5 |
PROSPERO |
|
low complexity region
|
1767 |
1778 |
N/A |
INTRINSIC |
|
low complexity region
|
2211 |
2235 |
N/A |
INTRINSIC |
|
low complexity region
|
2240 |
2399 |
N/A |
INTRINSIC |
|
low complexity region
|
2402 |
2420 |
N/A |
INTRINSIC |
|
low complexity region
|
2446 |
2458 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.3%
- 20x: 97.4%
|
| Validation Efficiency |
99% (86/87) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing DBF4-type zinc finger domains. This gene is imprinted and paternally expressed in lymphocytes but is more stochastically expressed in the placenta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931429L15Rik |
T |
A |
9: 46,220,173 (GRCm39) |
M120L |
probably benign |
Het |
| Abat |
A |
G |
16: 8,396,166 (GRCm39) |
T48A |
probably damaging |
Het |
| Abca8a |
A |
T |
11: 109,969,634 (GRCm39) |
I314N |
probably damaging |
Het |
| Abr |
A |
T |
11: 76,352,155 (GRCm39) |
V108D |
probably damaging |
Het |
| Adamts17 |
T |
G |
7: 66,725,057 (GRCm39) |
L162V |
probably damaging |
Het |
| Adamts6 |
A |
T |
13: 104,433,899 (GRCm39) |
K109N |
probably damaging |
Het |
| Ago3 |
A |
G |
4: 126,241,595 (GRCm39) |
F68S |
probably damaging |
Het |
| Aifm3 |
T |
C |
16: 17,324,200 (GRCm39) |
|
probably null |
Het |
| Ankrd26 |
T |
C |
6: 118,512,104 (GRCm39) |
E506G |
probably benign |
Het |
| Apaf1 |
A |
G |
10: 90,903,066 (GRCm39) |
L185P |
probably damaging |
Het |
| Atp8b3 |
G |
T |
10: 80,355,896 (GRCm39) |
T1272K |
probably benign |
Het |
| Cars2 |
A |
G |
8: 11,587,304 (GRCm39) |
V193A |
probably benign |
Het |
| Ccn5 |
C |
T |
2: 163,667,160 (GRCm39) |
R54* |
probably null |
Het |
| Ccr8 |
A |
T |
9: 119,923,613 (GRCm39) |
I243F |
possibly damaging |
Het |
| Col12a1 |
A |
G |
9: 79,538,901 (GRCm39) |
V2465A |
probably damaging |
Het |
| Ctbp1 |
T |
C |
5: 33,416,616 (GRCm39) |
N127S |
probably benign |
Het |
| Ddx10 |
A |
G |
9: 53,149,377 (GRCm39) |
S117P |
probably damaging |
Het |
| Dgkb |
T |
C |
12: 38,189,494 (GRCm39) |
|
probably null |
Het |
| Dnah11 |
T |
A |
12: 117,916,273 (GRCm39) |
D3520V |
probably damaging |
Het |
| Dnah11 |
C |
T |
12: 117,918,630 (GRCm39) |
D1530N |
probably damaging |
Het |
| Dock5 |
T |
C |
14: 67,994,640 (GRCm39) |
T1807A |
probably benign |
Het |
| Drd3 |
C |
T |
16: 43,641,842 (GRCm39) |
T386I |
probably damaging |
Het |
| Dsg1b |
A |
G |
18: 20,542,316 (GRCm39) |
N941S |
probably damaging |
Het |
| Enpp3 |
T |
C |
10: 24,696,513 (GRCm39) |
T141A |
probably benign |
Het |
| Esyt1 |
A |
T |
10: 128,356,566 (GRCm39) |
C360S |
possibly damaging |
Het |
| Ethe1 |
T |
A |
7: 24,305,682 (GRCm39) |
V143D |
probably damaging |
Het |
| Fam170b |
A |
G |
14: 32,557,336 (GRCm39) |
D57G |
probably benign |
Het |
| Fam53c |
T |
C |
18: 34,901,229 (GRCm39) |
S49P |
probably damaging |
Het |
| Fbp1 |
G |
A |
13: 63,023,067 (GRCm39) |
L77F |
probably benign |
Het |
| Gm17093 |
A |
G |
14: 44,758,149 (GRCm39) |
E110G |
|
Het |
| Gm21976 |
G |
T |
13: 98,423,821 (GRCm39) |
|
silent |
Het |
| Golgb1 |
T |
C |
16: 36,733,978 (GRCm39) |
I1075T |
probably damaging |
Het |
| Grip2 |
T |
C |
6: 91,754,391 (GRCm39) |
D628G |
probably damaging |
Het |
| Gtpbp1 |
G |
T |
15: 79,601,929 (GRCm39) |
L557F |
probably benign |
Het |
| Ighv12-3 |
A |
T |
12: 114,330,204 (GRCm39) |
F97Y |
probably benign |
Het |
| Itga8 |
T |
C |
2: 12,196,045 (GRCm39) |
H635R |
possibly damaging |
Het |
| Itgb7 |
A |
G |
15: 102,127,037 (GRCm39) |
L466S |
probably damaging |
Het |
| Klc2 |
T |
C |
19: 5,161,864 (GRCm39) |
D277G |
probably benign |
Het |
| Ktn1 |
A |
G |
14: 47,901,248 (GRCm39) |
E2G |
probably damaging |
Het |
| Lcmt1 |
T |
A |
7: 123,000,669 (GRCm39) |
Y68N |
probably damaging |
Het |
| Marchf10 |
G |
T |
11: 105,280,815 (GRCm39) |
S490* |
probably null |
Het |
| Mterf1b |
A |
T |
5: 4,246,437 (GRCm39) |
Y26F |
probably benign |
Het |
| Myo18b |
T |
A |
5: 113,006,346 (GRCm39) |
I855F |
probably benign |
Het |
| Nek4 |
G |
A |
14: 30,675,915 (GRCm39) |
M83I |
probably damaging |
Het |
| Nicn1 |
C |
T |
9: 108,171,708 (GRCm39) |
R163C |
possibly damaging |
Het |
| Nos1 |
T |
C |
5: 118,017,405 (GRCm39) |
V256A |
probably benign |
Het |
| Nr1h2 |
T |
C |
7: 44,201,463 (GRCm39) |
T50A |
probably benign |
Het |
| Or14c42-ps1 |
T |
A |
7: 86,211,317 (GRCm39) |
*126K |
probably null |
Het |
| Or4n4 |
A |
C |
14: 50,518,816 (GRCm39) |
M298R |
possibly damaging |
Het |
| Ovol2 |
G |
C |
2: 144,147,834 (GRCm39) |
R172G |
probably damaging |
Het |
| Parp14 |
A |
G |
16: 35,677,187 (GRCm39) |
I927T |
probably damaging |
Het |
| Pcdhga7 |
T |
A |
18: 37,848,879 (GRCm39) |
H295Q |
probably benign |
Het |
| Pkhd1l1 |
C |
T |
15: 44,400,291 (GRCm39) |
T2145I |
probably damaging |
Het |
| Plekhs1 |
C |
T |
19: 56,461,680 (GRCm39) |
T139I |
possibly damaging |
Het |
| Rab11fip3 |
T |
A |
17: 26,231,007 (GRCm39) |
D746V |
probably damaging |
Het |
| Rnf214 |
A |
C |
9: 45,809,728 (GRCm39) |
|
probably null |
Het |
| Rtn4ip1 |
A |
T |
10: 43,822,415 (GRCm39) |
|
probably null |
Het |
| S1pr1 |
T |
C |
3: 115,505,569 (GRCm39) |
R342G |
|
Het |
| Serpina1f |
T |
C |
12: 103,656,131 (GRCm39) |
S366G |
probably benign |
Het |
| Sestd1 |
A |
T |
2: 77,042,708 (GRCm39) |
M282K |
probably benign |
Het |
| Siglecf |
T |
G |
7: 43,001,140 (GRCm39) |
V36G |
probably damaging |
Het |
| Slc1a1 |
T |
C |
19: 28,886,869 (GRCm39) |
V410A |
probably damaging |
Het |
| Slc38a4 |
C |
A |
15: 96,917,684 (GRCm39) |
D14Y |
probably benign |
Het |
| Slk |
C |
T |
19: 47,610,748 (GRCm39) |
T806M |
probably damaging |
Het |
| Slurp2 |
C |
A |
15: 74,615,249 (GRCm39) |
V48F |
possibly damaging |
Het |
| Socs1 |
A |
G |
16: 10,602,642 (GRCm39) |
S32P |
possibly damaging |
Het |
| Son |
T |
C |
16: 91,455,057 (GRCm39) |
V1268A |
possibly damaging |
Het |
| Sp7 |
C |
A |
15: 102,274,880 (GRCm39) |
|
probably benign |
Het |
| Speer4a2 |
T |
G |
5: 26,290,745 (GRCm39) |
E142A |
probably benign |
Het |
| Taar7b |
T |
G |
10: 23,876,359 (GRCm39) |
S175A |
probably benign |
Het |
| Tet2 |
T |
C |
3: 133,193,804 (GRCm39) |
N210S |
probably benign |
Het |
| Tkfc |
T |
C |
19: 10,570,700 (GRCm39) |
D492G |
probably damaging |
Het |
| Tmc7 |
G |
A |
7: 118,160,228 (GRCm39) |
P203L |
probably benign |
Het |
| Trmt9b |
A |
G |
8: 36,972,729 (GRCm39) |
K60E |
probably damaging |
Het |
| Tshz2 |
C |
A |
2: 169,726,524 (GRCm39) |
F373L |
probably damaging |
Het |
| Ttc29 |
T |
A |
8: 79,042,336 (GRCm39) |
L307Q |
probably damaging |
Het |
| Tubd1 |
G |
A |
11: 86,439,659 (GRCm39) |
M1I |
probably null |
Het |
| Vmn1r62 |
T |
A |
7: 5,678,601 (GRCm39) |
M94K |
probably damaging |
Het |
| Vmn2r125 |
T |
C |
4: 156,703,186 (GRCm39) |
I188T |
possibly damaging |
Het |
| Vmn2r5 |
T |
C |
3: 64,398,564 (GRCm39) |
D805G |
probably damaging |
Het |
| Vmn2r6 |
A |
T |
3: 64,463,576 (GRCm39) |
D419E |
probably damaging |
Het |
| Vps39 |
A |
T |
2: 120,174,687 (GRCm39) |
Y98* |
probably null |
Het |
| Zdhhc6 |
T |
C |
19: 55,287,239 (GRCm39) |
E407G |
probably benign |
Het |
| Zfp407 |
A |
G |
18: 84,577,057 (GRCm39) |
I1352T |
probably damaging |
Het |
| Zfp607a |
A |
G |
7: 27,578,786 (GRCm39) |
K619E |
possibly damaging |
Het |
| Zfp811 |
A |
T |
17: 33,017,622 (GRCm39) |
N139K |
probably benign |
Het |
|
| Other mutations in Zdbf2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00790:Zdbf2
|
APN |
1 |
63,345,673 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL00796:Zdbf2
|
APN |
1 |
63,346,364 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL00801:Zdbf2
|
APN |
1 |
63,342,197 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL02803:Zdbf2
|
APN |
1 |
63,342,236 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R0143:Zdbf2
|
UTSW |
1 |
63,347,233 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0147:Zdbf2
|
UTSW |
1 |
63,343,165 (GRCm39) |
nonsense |
probably null |
|
|
R0148:Zdbf2
|
UTSW |
1 |
63,343,165 (GRCm39) |
nonsense |
probably null |
|
|
R0433:Zdbf2
|
UTSW |
1 |
63,345,302 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R0502:Zdbf2
|
UTSW |
1 |
63,344,449 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R0645:Zdbf2
|
UTSW |
1 |
63,344,109 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0765:Zdbf2
|
UTSW |
1 |
63,344,882 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1068:Zdbf2
|
UTSW |
1 |
63,342,589 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1216:Zdbf2
|
UTSW |
1 |
63,342,161 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1235:Zdbf2
|
UTSW |
1 |
63,348,232 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1352:Zdbf2
|
UTSW |
1 |
63,342,212 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1402:Zdbf2
|
UTSW |
1 |
63,342,786 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1402:Zdbf2
|
UTSW |
1 |
63,342,786 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1435:Zdbf2
|
UTSW |
1 |
63,342,199 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1562:Zdbf2
|
UTSW |
1 |
63,342,747 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1624:Zdbf2
|
UTSW |
1 |
63,343,018 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1635:Zdbf2
|
UTSW |
1 |
63,343,493 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1644:Zdbf2
|
UTSW |
1 |
63,348,131 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1662:Zdbf2
|
UTSW |
1 |
63,343,408 (GRCm39) |
nonsense |
probably null |
|
|
R1700:Zdbf2
|
UTSW |
1 |
63,341,900 (GRCm39) |
missense |
unknown |
|
|
R1720:Zdbf2
|
UTSW |
1 |
63,342,436 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1853:Zdbf2
|
UTSW |
1 |
63,344,701 (GRCm39) |
frame shift |
probably null |
|
|
R1854:Zdbf2
|
UTSW |
1 |
63,344,701 (GRCm39) |
frame shift |
probably null |
|
|
R1973:Zdbf2
|
UTSW |
1 |
63,348,860 (GRCm39) |
missense |
unknown |
|
|
R2336:Zdbf2
|
UTSW |
1 |
63,342,623 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2428:Zdbf2
|
UTSW |
1 |
63,344,774 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3010:Zdbf2
|
UTSW |
1 |
63,342,224 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R3034:Zdbf2
|
UTSW |
1 |
63,343,364 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3079:Zdbf2
|
UTSW |
1 |
63,346,636 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3196:Zdbf2
|
UTSW |
1 |
63,347,579 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R3711:Zdbf2
|
UTSW |
1 |
63,347,830 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R3845:Zdbf2
|
UTSW |
1 |
63,347,483 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4093:Zdbf2
|
UTSW |
1 |
63,348,940 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4250:Zdbf2
|
UTSW |
1 |
63,342,020 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4592:Zdbf2
|
UTSW |
1 |
63,345,750 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4721:Zdbf2
|
UTSW |
1 |
63,347,951 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4779:Zdbf2
|
UTSW |
1 |
63,342,397 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4928:Zdbf2
|
UTSW |
1 |
63,347,973 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4943:Zdbf2
|
UTSW |
1 |
63,342,073 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5025:Zdbf2
|
UTSW |
1 |
63,342,809 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5095:Zdbf2
|
UTSW |
1 |
63,348,232 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5149:Zdbf2
|
UTSW |
1 |
63,344,062 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5326:Zdbf2
|
UTSW |
1 |
63,343,570 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5341:Zdbf2
|
UTSW |
1 |
63,347,092 (GRCm39) |
missense |
probably benign |
0.27 |
|
R5511:Zdbf2
|
UTSW |
1 |
63,344,836 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5809:Zdbf2
|
UTSW |
1 |
63,345,035 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5902:Zdbf2
|
UTSW |
1 |
63,345,685 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6162:Zdbf2
|
UTSW |
1 |
63,319,977 (GRCm39) |
start gained |
probably benign |
|
|
R6245:Zdbf2
|
UTSW |
1 |
63,343,592 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6332:Zdbf2
|
UTSW |
1 |
63,346,981 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6361:Zdbf2
|
UTSW |
1 |
63,342,480 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6489:Zdbf2
|
UTSW |
1 |
63,346,637 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6517:Zdbf2
|
UTSW |
1 |
63,344,679 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6624:Zdbf2
|
UTSW |
1 |
63,343,073 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6643:Zdbf2
|
UTSW |
1 |
63,343,667 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6786:Zdbf2
|
UTSW |
1 |
63,343,679 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6808:Zdbf2
|
UTSW |
1 |
63,347,687 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6896:Zdbf2
|
UTSW |
1 |
63,348,031 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6997:Zdbf2
|
UTSW |
1 |
63,329,925 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7011:Zdbf2
|
UTSW |
1 |
63,345,925 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7058:Zdbf2
|
UTSW |
1 |
63,346,563 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7066:Zdbf2
|
UTSW |
1 |
63,346,718 (GRCm39) |
missense |
probably benign |
|
|
R7177:Zdbf2
|
UTSW |
1 |
63,334,120 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7184:Zdbf2
|
UTSW |
1 |
63,345,664 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7273:Zdbf2
|
UTSW |
1 |
63,342,563 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7387:Zdbf2
|
UTSW |
1 |
63,343,198 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7468:Zdbf2
|
UTSW |
1 |
63,346,669 (GRCm39) |
missense |
probably benign |
|
|
R7695:Zdbf2
|
UTSW |
1 |
63,346,529 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7712:Zdbf2
|
UTSW |
1 |
63,344,530 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7735:Zdbf2
|
UTSW |
1 |
63,343,264 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7736:Zdbf2
|
UTSW |
1 |
63,347,166 (GRCm39) |
nonsense |
probably null |
|
|
R7759:Zdbf2
|
UTSW |
1 |
63,347,535 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7796:Zdbf2
|
UTSW |
1 |
63,342,583 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7908:Zdbf2
|
UTSW |
1 |
63,345,986 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7970:Zdbf2
|
UTSW |
1 |
63,343,330 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8076:Zdbf2
|
UTSW |
1 |
63,345,260 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8152:Zdbf2
|
UTSW |
1 |
63,345,572 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8195:Zdbf2
|
UTSW |
1 |
63,343,225 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8272:Zdbf2
|
UTSW |
1 |
63,345,142 (GRCm39) |
missense |
probably benign |
|
|
R8306:Zdbf2
|
UTSW |
1 |
63,343,234 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R8309:Zdbf2
|
UTSW |
1 |
63,345,750 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8323:Zdbf2
|
UTSW |
1 |
63,342,073 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R8400:Zdbf2
|
UTSW |
1 |
63,344,135 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8443:Zdbf2
|
UTSW |
1 |
63,345,166 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8460:Zdbf2
|
UTSW |
1 |
63,348,729 (GRCm39) |
small deletion |
probably benign |
|
|
R8528:Zdbf2
|
UTSW |
1 |
63,342,545 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8812:Zdbf2
|
UTSW |
1 |
63,347,272 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9061:Zdbf2
|
UTSW |
1 |
63,346,296 (GRCm39) |
missense |
|
|
|
R9072:Zdbf2
|
UTSW |
1 |
63,344,923 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9232:Zdbf2
|
UTSW |
1 |
63,347,168 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9257:Zdbf2
|
UTSW |
1 |
63,345,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9411:Zdbf2
|
UTSW |
1 |
63,343,288 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9470:Zdbf2
|
UTSW |
1 |
63,344,784 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9606:Zdbf2
|
UTSW |
1 |
63,342,536 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9621:Zdbf2
|
UTSW |
1 |
63,342,635 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
RF021:Zdbf2
|
UTSW |
1 |
63,341,811 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
X0018:Zdbf2
|
UTSW |
1 |
63,344,510 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
X0027:Zdbf2
|
UTSW |
1 |
63,347,166 (GRCm39) |
nonsense |
probably null |
|
|
X0057:Zdbf2
|
UTSW |
1 |
63,344,549 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
X0063:Zdbf2
|
UTSW |
1 |
63,344,696 (GRCm39) |
missense |
probably benign |
0.04 |
|
Z1176:Zdbf2
|
UTSW |
1 |
63,343,404 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
Z1177:Zdbf2
|
UTSW |
1 |
63,348,362 (GRCm39) |
missense |
unknown |
|
|
Z1177:Zdbf2
|
UTSW |
1 |
63,343,245 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CCAGGGTAAGAAAGTGACTTTTG -3'
(R):5'- AAGCCCCTCTGCTAAGGAAC -3'
Sequencing Primer
(F):5'- AGGGTAAGAAAGTGACTTTTGACTTG -3'
(R):5'- CTGCTAAGGAACAAGACTGTTTACC -3'
|
| Posted On |
2021-08-31 |
Incidental Mutation