Mutagenetix > Incidental Mutation

Incidental Mutation 'R2072:Cnot1'

227238

Institutional Source

Beutler Lab

Gene Symbol

Cnot1

Ensembl Gene

ENSMUSG00000036550

Gene Name

CCR4-NOT transcription complex, subunit 1

Synonyms

6030411K04Rik

MMRRC Submission

040077-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R2072 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

95719451-95807464 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to T at 95739833 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Lysine at position 1592 (T1592K)

Ref Sequence

ENSEMBL: ENSMUSP00000148735 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000068452] [ENSMUST00000098473] [ENSMUST00000211887] [ENSMUST00000213006]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000068452
AA Change: T1587K

PolyPhen 2 Score 0.526 (Sensitivity: 0.88; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000063565
Gene: ENSMUSG00000036550
AA Change: T1587K

Domain	Start	End	E-Value	Type
low complexity region	181	189	N/A	INTRINSIC
low complexity region	687	698	N/A	INTRINSIC
low complexity region	779	796	N/A	INTRINSIC
PDB:4J8S\|A	798	999	1e-137	PDB
low complexity region	1011	1028	N/A	INTRINSIC
low complexity region	1031	1055	N/A	INTRINSIC
PDB:4CT4\|C	1056	1295	1e-148	PDB
low complexity region	1296	1308	N/A	INTRINSIC
low complexity region	1328	1345	N/A	INTRINSIC
Pfam:DUF3819	1381	1530	2.5e-56	PFAM
low complexity region	1634	1648	N/A	INTRINSIC
Pfam:Not1	1991	2305	2.4e-125	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000098473
AA Change: T1592K

PolyPhen 2 Score 0.175 (Sensitivity: 0.92; Specificity: 0.87)

SMART Domains

Protein: ENSMUSP00000096073
Gene: ENSMUSG00000036550
AA Change: T1592K

Domain	Start	End	E-Value	Type
low complexity region	181	189	N/A	INTRINSIC
Pfam:CNOT1_HEAT	500	656	2.4e-57	PFAM
low complexity region	687	698	N/A	INTRINSIC
low complexity region	779	796	N/A	INTRINSIC
Pfam:CNOT1_TTP_bind	812	1004	1.4e-87	PFAM
low complexity region	1016	1033	N/A	INTRINSIC
low complexity region	1036	1060	N/A	INTRINSIC
Pfam:CNOT1_CAF1_bind	1087	1313	5.7e-99	PFAM
low complexity region	1333	1350	N/A	INTRINSIC
Pfam:DUF3819	1387	1534	2.3e-57	PFAM
low complexity region	1639	1653	N/A	INTRINSIC
Pfam:Not1	1998	2357	5.7e-157	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000211887
AA Change: T1585K

PolyPhen 2 Score 0.677 (Sensitivity: 0.86; Specificity: 0.92)

Predicted Effect

probably benign
Transcript: ENSMUST00000211973

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000212195

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000212340

Predicted Effect

probably benign
Transcript: ENSMUST00000212415

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000212712

Predicted Effect

possibly damaging
Transcript: ENSMUST00000213006
AA Change: T1592K

PolyPhen 2 Score 0.895 (Sensitivity: 0.82; Specificity: 0.94)

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.4%
20x: 95.3%

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice hmozygous for a conditional allele activated in cardiomyocytes exhibit postnatal lethality, decreased cardiac muscle contractility, prolonged QT interval and cardiac muscle cell death. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 76 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
0610040J01Rik	G	C	5: 63,898,737 (GRCm38)	R272P	possibly damaging	Het
9130011E15Rik	A	T	19: 45,965,381 (GRCm38)	I188K	probably damaging	Het
Ablim3	A	T	18: 61,857,088 (GRCm38)	D83E	possibly damaging	Het
Aco1	G	A	4: 40,183,605 (GRCm38)	G508S	probably damaging	Het
Adamts13	C	A	2: 27,005,425 (GRCm38)	T1176N	probably benign	Het
Adgre5	T	C	8: 83,727,804 (GRCm38)	T357A	probably benign	Het
Akap8l	C	T	17: 32,332,483 (GRCm38)	R511H	probably damaging	Het
Ankrd33	T	C	15: 101,119,636 (GRCm38)	V310A	probably benign	Het
Bnipl	C	T	3: 95,244,211 (GRCm38)	G232E	probably damaging	Het
Btbd17	A	T	11: 114,791,952 (GRCm38)		probably null	Het
Cacna1s	G	A	1: 136,079,504 (GRCm38)	V173I	probably benign	Het
Ccdc122	T	C	14: 77,068,951 (GRCm38)		probably null	Het
Ces1a	T	A	8: 93,048,075 (GRCm38)	N12Y	probably benign	Het
Chrdl1	T	C	X: 143,303,418 (GRCm38)	I231V	probably benign	Het
Ciita	C	T	16: 10,518,353 (GRCm38)	T958I	probably benign	Het
Dcaf15	T	C	8: 84,101,741 (GRCm38)	D240G	probably damaging	Het
Ddx58	A	T	4: 40,224,069 (GRCm38)		probably null	Het
Dlgap1	C	T	17: 70,662,770 (GRCm38)	R524C	probably damaging	Het
Dmd	G	C	X: 84,312,483 (GRCm38)	A2257P	probably benign	Het
Dsg1c	A	G	18: 20,275,252 (GRCm38)	M453V	probably benign	Het
Ednrb	G	T	14: 103,817,099 (GRCm38)	N432K	probably benign	Het
Fcgbp	G	A	7: 28,120,389 (GRCm38)	G2514S	probably damaging	Het
Fez1	A	G	9: 36,867,945 (GRCm38)	K306R	probably benign	Het
Fmo4	A	G	1: 162,809,887 (GRCm38)	V12A	probably benign	Het
Fpgt	T	C	3: 155,087,874 (GRCm38)	Y172C	probably damaging	Het
Fsip2	T	A	2: 83,008,815 (GRCm38)	F6976I	possibly damaging	Het
Galnt12	C	T	4: 47,108,477 (GRCm38)	R205*	probably null	Het
Grik5	A	T	7: 25,015,313 (GRCm38)	M752K	possibly damaging	Het
Herc2	A	G	7: 56,226,964 (GRCm38)	N4516S	probably damaging	Het
Ifrd2	A	T	9: 107,592,545 (GRCm38)	D439V	probably damaging	Het
Igsf3	A	G	3: 101,439,515 (GRCm38)	T609A	probably benign	Het
Kif5a	T	C	10: 127,245,369 (GRCm38)	D232G	probably damaging	Het
Lgi2	A	G	5: 52,538,505 (GRCm38)	S371P	probably damaging	Het
March3	A	T	18: 56,811,853 (GRCm38)	V56E	possibly damaging	Het
Mib2	T	C	4: 155,659,701 (GRCm38)	D168G	probably damaging	Het
Nhs	T	A	X: 161,842,721 (GRCm38)	H544L	probably damaging	Het
Nlrp2	A	G	7: 5,325,006 (GRCm38)	S683P	probably damaging	Het
Olfr1260	C	A	2: 89,978,213 (GRCm38)	T145K	probably benign	Het
Olfr1454	A	T	19: 13,063,680 (GRCm38)	M90L	probably benign	Het
Olfr527	T	C	7: 140,336,653 (GRCm38)	S264P	possibly damaging	Het
Onecut3	T	G	10: 80,495,014 (GRCm38)	L3V	unknown	Het
Otogl	C	T	10: 107,781,043 (GRCm38)	C1791Y	probably damaging	Het
Paip1	T	C	13: 119,430,262 (GRCm38)	V128A	possibly damaging	Het
Pcnx2	A	T	8: 125,761,742 (GRCm38)	C1688S	possibly damaging	Het
Pdzd2	A	G	15: 12,385,819 (GRCm38)	L955P	probably damaging	Het
Phlpp2	T	C	8: 109,928,492 (GRCm38)	S605P	possibly damaging	Het
Pkhd1l1	G	T	15: 44,558,639 (GRCm38)	A3102S	probably damaging	Het
Plxnb2	G	T	15: 89,158,451 (GRCm38)	R1545S	probably damaging	Het
Ppp4c	T	C	7: 126,787,348 (GRCm38)		probably null	Het
Prune1	C	T	3: 95,255,408 (GRCm38)	R318Q	probably benign	Het
Psg27	A	G	7: 18,565,009 (GRCm38)	L129P	probably benign	Het
Psg27	T	C	7: 18,560,417 (GRCm38)	D355G	probably damaging	Het
Psmc6	A	G	14: 45,329,866 (GRCm38)	K7E	possibly damaging	Het
Reln	A	T	5: 21,919,177 (GRCm38)	V2777E	probably damaging	Het
Scn11a	G	T	9: 119,811,208 (GRCm38)	A207E	possibly damaging	Het
Slc5a5	C	T	8: 70,892,439 (GRCm38)	G75R	possibly damaging	Het
Smarcd2	A	T	11: 106,265,307 (GRCm38)	L42*	probably null	Het
Smg1	T	C	7: 118,163,166 (GRCm38)		probably benign	Het
Smurf2	T	A	11: 106,841,769 (GRCm38)	Q335L	probably benign	Het
Sspo	A	T	6: 48,473,517 (GRCm38)	H2580L	probably benign	Het
Stk3	T	C	15: 34,959,049 (GRCm38)	M256V	possibly damaging	Het
Syt1	A	G	10: 108,583,972 (GRCm38)	I276T	probably damaging	Het
Syt10	C	T	15: 89,790,776 (GRCm38)	D456N	probably damaging	Het
Taar9	A	T	10: 24,108,979 (GRCm38)	C186S	probably damaging	Het
Tnrc6b	C	T	15: 80,882,965 (GRCm38)	P977L	possibly damaging	Het
Trp53bp2	A	G	1: 182,458,867 (GRCm38)	T1091A	probably benign	Het
Ttn	G	T	2: 76,937,776 (GRCm38)	T2947N	probably damaging	Het
Ube2q1	T	C	3: 89,779,571 (GRCm38)		probably null	Het
Ube3c	A	G	5: 29,635,640 (GRCm38)	E671G	probably benign	Het
Upf3a	A	G	8: 13,785,850 (GRCm38)	K56R	possibly damaging	Het
Vmn2r15	A	T	5: 109,286,753 (GRCm38)	M695K	possibly damaging	Het
Vmn2r3	A	T	3: 64,275,072 (GRCm38)	M402K	possibly damaging	Het
Zfp354b	T	A	11: 50,922,452 (GRCm38)	R549*	probably null	Het
Zfp37	A	T	4: 62,191,708 (GRCm38)	M411K	probably damaging	Het
Zfp747	T	A	7: 127,373,970 (GRCm38)	T343S	possibly damaging	Het
Zfp853	T	A	5: 143,289,382 (GRCm38)	Q161L	unknown	Het

Other mutations in Cnot1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00516:Cnot1	APN	8	95,726,079 (GRCm38)	missense	probably damaging	1.00
IGL01340:Cnot1	APN	8	95,760,537 (GRCm38)	missense	probably damaging	1.00
IGL01457:Cnot1	APN	8	95,741,009 (GRCm38)	missense	probably damaging	1.00
IGL01505:Cnot1	APN	8	95,728,718 (GRCm38)	missense	probably damaging	0.98
IGL02401:Cnot1	APN	8	95,756,133 (GRCm38)	missense	possibly damaging	0.95
IGL02693:Cnot1	APN	8	95,773,485 (GRCm38)	missense	probably damaging	1.00
IGL02696:Cnot1	APN	8	95,745,017 (GRCm38)	missense	probably benign	0.00
IGL02754:Cnot1	APN	8	95,755,078 (GRCm38)	missense	probably benign	0.03
IGL03092:Cnot1	APN	8	95,769,615 (GRCm38)	intron	probably benign
IGL03174:Cnot1	APN	8	95,761,355 (GRCm38)	missense	probably damaging	1.00
IGL03310:Cnot1	APN	8	95,735,680 (GRCm38)	splice site	probably benign
IGL03371:Cnot1	APN	8	95,774,716 (GRCm38)	missense	possibly damaging	0.85
Affiliate	UTSW	8	95,765,125 (GRCm38)	missense	probably damaging	0.99
Barge	UTSW	8	95,734,129 (GRCm38)	missense	probably benign	0.13
Byproduct	UTSW	8	95,745,647 (GRCm38)	frame shift	probably null
Chairman	UTSW	8	95,765,027 (GRCm38)	missense	possibly damaging	0.95
cohort	UTSW	8	95,735,749 (GRCm38)	missense	probably damaging	0.99
Director	UTSW	8	95,765,062 (GRCm38)	missense	probably benign	0.15
kowloon	UTSW	8	95,788,658 (GRCm38)	missense	probably damaging	1.00
Quorum	UTSW	8	95,726,118 (GRCm38)	missense	probably damaging	1.00
tugboat	UTSW	8	95,773,618 (GRCm38)	missense	probably damaging	0.99
Xiao	UTSW	8	95,730,420 (GRCm38)	missense	probably damaging	1.00
BB001:Cnot1	UTSW	8	95,745,647 (GRCm38)	frame shift	probably null
BB003:Cnot1	UTSW	8	95,745,647 (GRCm38)	frame shift	probably null
BB011:Cnot1	UTSW	8	95,745,647 (GRCm38)	frame shift	probably null
BB013:Cnot1	UTSW	8	95,745,647 (GRCm38)	frame shift	probably null
R0008:Cnot1	UTSW	8	95,761,341 (GRCm38)	missense	probably damaging	1.00
R0008:Cnot1	UTSW	8	95,761,341 (GRCm38)	missense	probably damaging	1.00
R0091:Cnot1	UTSW	8	95,763,144 (GRCm38)	missense	probably damaging	1.00
R0335:Cnot1	UTSW	8	95,772,000 (GRCm38)	missense	probably benign	0.02
R0409:Cnot1	UTSW	8	95,748,855 (GRCm38)	missense	probably damaging	0.96
R0445:Cnot1	UTSW	8	95,760,208 (GRCm38)	missense	probably damaging	1.00
R1505:Cnot1	UTSW	8	95,728,667 (GRCm38)	missense	probably damaging	1.00
R1517:Cnot1	UTSW	8	95,743,213 (GRCm38)	missense	probably benign	0.38
R1640:Cnot1	UTSW	8	95,769,832 (GRCm38)	missense	probably damaging	0.98
R1737:Cnot1	UTSW	8	95,748,276 (GRCm38)	missense	probably damaging	0.98
R1755:Cnot1	UTSW	8	95,724,577 (GRCm38)	missense	probably damaging	1.00
R1901:Cnot1	UTSW	8	95,743,121 (GRCm38)	missense	possibly damaging	0.50
R1902:Cnot1	UTSW	8	95,743,121 (GRCm38)	missense	possibly damaging	0.50
R1903:Cnot1	UTSW	8	95,743,121 (GRCm38)	missense	possibly damaging	0.50
R1988:Cnot1	UTSW	8	95,741,944 (GRCm38)	missense	possibly damaging	0.89
R2051:Cnot1	UTSW	8	95,724,593 (GRCm38)	missense	possibly damaging	0.47
R2054:Cnot1	UTSW	8	95,739,841 (GRCm38)	missense	possibly damaging	0.55
R2074:Cnot1	UTSW	8	95,739,833 (GRCm38)	missense	possibly damaging	0.89
R2075:Cnot1	UTSW	8	95,739,833 (GRCm38)	missense	possibly damaging	0.89
R2093:Cnot1	UTSW	8	95,775,358 (GRCm38)	missense	probably damaging	1.00
R2116:Cnot1	UTSW	8	95,726,153 (GRCm38)	missense	probably damaging	1.00
R2191:Cnot1	UTSW	8	95,761,426 (GRCm38)	missense	probably damaging	0.98
R2238:Cnot1	UTSW	8	95,769,521 (GRCm38)	missense	probably benign	0.04
R2239:Cnot1	UTSW	8	95,769,521 (GRCm38)	missense	probably benign	0.04
R2251:Cnot1	UTSW	8	95,763,186 (GRCm38)	missense	probably benign	0.00
R2252:Cnot1	UTSW	8	95,763,186 (GRCm38)	missense	probably benign	0.00
R2253:Cnot1	UTSW	8	95,763,186 (GRCm38)	missense	probably benign	0.00
R2315:Cnot1	UTSW	8	95,749,062 (GRCm38)	missense	probably damaging	1.00
R2431:Cnot1	UTSW	8	95,774,652 (GRCm38)	missense	probably damaging	1.00
R2988:Cnot1	UTSW	8	95,744,278 (GRCm38)	missense	possibly damaging	0.80
R2989:Cnot1	UTSW	8	95,744,278 (GRCm38)	missense	possibly damaging	0.80
R3108:Cnot1	UTSW	8	95,735,749 (GRCm38)	missense	probably damaging	0.99
R3109:Cnot1	UTSW	8	95,735,749 (GRCm38)	missense	probably damaging	0.99
R3114:Cnot1	UTSW	8	95,744,278 (GRCm38)	missense	possibly damaging	0.80
R3115:Cnot1	UTSW	8	95,744,278 (GRCm38)	missense	possibly damaging	0.80
R3153:Cnot1	UTSW	8	95,744,278 (GRCm38)	missense	possibly damaging	0.80
R3154:Cnot1	UTSW	8	95,744,278 (GRCm38)	missense	possibly damaging	0.80
R4112:Cnot1	UTSW	8	95,773,618 (GRCm38)	missense	probably damaging	0.99
R4359:Cnot1	UTSW	8	95,739,848 (GRCm38)	missense	probably damaging	1.00
R4382:Cnot1	UTSW	8	95,769,779 (GRCm38)	missense	probably damaging	0.97
R4747:Cnot1	UTSW	8	95,774,682 (GRCm38)	missense	probably benign	0.27
R4910:Cnot1	UTSW	8	95,733,231 (GRCm38)	missense	probably benign	0.43
R4913:Cnot1	UTSW	8	95,763,067 (GRCm38)	missense	possibly damaging	0.63
R4971:Cnot1	UTSW	8	95,721,626 (GRCm38)	missense	probably damaging	1.00
R5056:Cnot1	UTSW	8	95,741,008 (GRCm38)	missense	probably damaging	1.00
R5092:Cnot1	UTSW	8	95,752,768 (GRCm38)	missense	possibly damaging	0.91
R5101:Cnot1	UTSW	8	95,760,187 (GRCm38)	missense	possibly damaging	0.90
R5498:Cnot1	UTSW	8	95,757,355 (GRCm38)	missense	possibly damaging	0.92
R5719:Cnot1	UTSW	8	95,744,296 (GRCm38)	missense	possibly damaging	0.92
R5850:Cnot1	UTSW	8	95,734,147 (GRCm38)	nonsense	probably null
R5956:Cnot1	UTSW	8	95,754,978 (GRCm38)	critical splice donor site	probably null
R5981:Cnot1	UTSW	8	95,788,665 (GRCm38)	missense	probably damaging	1.00
R6093:Cnot1	UTSW	8	95,748,894 (GRCm38)	missense	probably benign	0.03
R6108:Cnot1	UTSW	8	95,730,420 (GRCm38)	missense	probably damaging	1.00
R6261:Cnot1	UTSW	8	95,741,921 (GRCm38)	missense	probably benign	0.00
R6632:Cnot1	UTSW	8	95,773,267 (GRCm38)	intron	probably benign
R6882:Cnot1	UTSW	8	95,720,426 (GRCm38)	missense	possibly damaging	0.85
R6966:Cnot1	UTSW	8	95,724,532 (GRCm38)	missense	probably damaging	1.00
R6985:Cnot1	UTSW	8	95,734,129 (GRCm38)	missense	probably benign	0.13
R7210:Cnot1	UTSW	8	95,788,658 (GRCm38)	missense	probably damaging	1.00
R7410:Cnot1	UTSW	8	95,733,159 (GRCm38)	missense	possibly damaging	0.77
R7623:Cnot1	UTSW	8	95,727,648 (GRCm38)	missense	probably damaging	1.00
R7624:Cnot1	UTSW	8	95,751,819 (GRCm38)	missense	probably damaging	1.00
R7695:Cnot1	UTSW	8	95,770,632 (GRCm38)	missense	probably benign	0.03
R7703:Cnot1	UTSW	8	95,760,098 (GRCm38)	critical splice donor site	probably null
R7771:Cnot1	UTSW	8	95,765,125 (GRCm38)	missense	probably damaging	0.99
R7800:Cnot1	UTSW	8	95,765,062 (GRCm38)	missense	probably benign	0.15
R7809:Cnot1	UTSW	8	95,751,778 (GRCm38)	missense	probably damaging	1.00
R7857:Cnot1	UTSW	8	95,745,647 (GRCm38)	frame shift	probably null
R7914:Cnot1	UTSW	8	95,745,647 (GRCm38)	frame shift	probably null
R7924:Cnot1	UTSW	8	95,745,647 (GRCm38)	frame shift	probably null
R7926:Cnot1	UTSW	8	95,745,647 (GRCm38)	frame shift	probably null
R7981:Cnot1	UTSW	8	95,763,169 (GRCm38)	missense	probably damaging	1.00
R8004:Cnot1	UTSW	8	95,752,752 (GRCm38)	missense	probably benign	0.03
R8061:Cnot1	UTSW	8	95,765,027 (GRCm38)	missense	possibly damaging	0.95
R8185:Cnot1	UTSW	8	95,761,351 (GRCm38)	missense	probably damaging	1.00
R8269:Cnot1	UTSW	8	95,751,761 (GRCm38)	missense	probably damaging	1.00
R8306:Cnot1	UTSW	8	95,747,021 (GRCm38)	missense	probably benign	0.05
R8322:Cnot1	UTSW	8	95,769,844 (GRCm38)	missense	probably benign	0.00
R8427:Cnot1	UTSW	8	95,734,324 (GRCm38)	missense	probably benign	0.01
R8723:Cnot1	UTSW	8	95,736,279 (GRCm38)	missense	probably benign	0.00
R8934:Cnot1	UTSW	8	95,765,067 (GRCm38)	missense	probably benign	0.04
R9025:Cnot1	UTSW	8	95,749,032 (GRCm38)	missense	probably benign
R9179:Cnot1	UTSW	8	95,773,426 (GRCm38)	missense	probably benign	0.16
R9280:Cnot1	UTSW	8	95,770,599 (GRCm38)	missense	probably benign	0.15
R9285:Cnot1	UTSW	8	95,726,118 (GRCm38)	missense	probably damaging	1.00
R9299:Cnot1	UTSW	8	95,741,820 (GRCm38)	missense	probably damaging	1.00
R9337:Cnot1	UTSW	8	95,741,820 (GRCm38)	missense	probably damaging	1.00
R9480:Cnot1	UTSW	8	95,770,710 (GRCm38)	missense	possibly damaging	0.94
R9548:Cnot1	UTSW	8	95,756,226 (GRCm38)	missense	probably benign	0.02
R9601:Cnot1	UTSW	8	95,756,207 (GRCm38)	missense	probably benign	0.02
R9629:Cnot1	UTSW	8	95,729,246 (GRCm38)	missense	probably damaging	0.98
R9752:Cnot1	UTSW	8	95,761,391 (GRCm38)	missense	probably damaging	1.00
R9764:Cnot1	UTSW	8	95,769,581 (GRCm38)	missense	probably benign	0.00
R9789:Cnot1	UTSW	8	95,729,144 (GRCm38)	missense	probably damaging	1.00
X0050:Cnot1	UTSW	8	95,743,098 (GRCm38)	splice site	probably null
Z1176:Cnot1	UTSW	8	95,748,277 (GRCm38)	missense	possibly damaging	0.73

Predicted Primers

PCR Primer
(F):5'- CTGCTTGACATGCTGATCTAAC -3'
(R):5'- TAGCTGGGCATTTTAGCAGG -3'

Sequencing Primer
(F):5'- CAAAGATCAGTTGTAACCAATGGC -3'
(R):5'- AGTTTGAGACCAGCCTGATC -3'

Posted On

2014-09-17