Incidental Mutation 'R5186:Pik3c2g'
| ID |
397879 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pik3c2g
|
| Ensembl Gene |
ENSMUSG00000030228 |
| Gene Name |
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma |
| Synonyms |
|
| MMRRC Submission |
042765-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.105)
|
| Stock # |
R5186 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
139587221-139969284 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 139622018 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 44
(V44A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000140368
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000032353]
[ENSMUST00000185968]
[ENSMUST00000187618]
[ENSMUST00000188066]
[ENSMUST00000190962]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000032353
AA Change: V44A
PolyPhen 2
Score 0.904 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000032353
Gene: ENSMUSG00000030228
AA Change: V44A
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1e8xa3
|
223 |
344 |
4e-33 |
SMART |
|
Blast:PI3K_rbd
|
272 |
345 |
7e-44 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000185968
AA Change: V44A
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000140368
Gene: ENSMUSG00000030228
AA Change: V44A
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1e8xa3
|
223 |
371 |
2e-42 |
SMART |
|
Blast:PI3K_rbd
|
272 |
371 |
2e-64 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000186585
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000187618
AA Change: V44A
PolyPhen 2
Score 0.904 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000141025
Gene: ENSMUSG00000030228
AA Change: V44A
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1e8xa3
|
223 |
344 |
4e-33 |
SMART |
|
Blast:PI3K_rbd
|
272 |
345 |
7e-44 |
BLAST |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000188066
AA Change: V44A
PolyPhen 2
Score 0.904 (Sensitivity: 0.82; Specificity: 0.94)
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000190962
AA Change: V44A
PolyPhen 2
Score 0.904 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000141141
Gene: ENSMUSG00000030228
AA Change: V44A
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1e8xa3
|
223 |
344 |
4e-33 |
SMART |
|
Blast:PI3K_rbd
|
272 |
345 |
7e-44 |
BLAST |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 95.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
PHENOTYPE: Mice homozygous for a knock-out allelel exhibit reduced liver glucogen accumulation, hyperlipidemia, adiposity and insulin resistance with age or after consumption of a high-fat diet. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 72 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca8a |
T |
C |
11: 110,091,599 (GRCm38) |
I6V |
probably null |
Het |
| Aox1 |
A |
G |
1: 58,068,370 (GRCm38) |
D601G |
probably damaging |
Het |
| Asic1 |
GCACC |
GCACCACC |
15: 99,698,803 (GRCm38) |
|
probably benign |
Het |
| Cacna1g |
T |
G |
11: 94,442,848 (GRCm38) |
N931T |
probably damaging |
Het |
| Ccdc14 |
T |
C |
16: 34,721,585 (GRCm38) |
F511L |
probably damaging |
Het |
| Cd177 |
T |
A |
7: 24,744,923 (GRCm38) |
E710V |
probably benign |
Het |
| Cep112 |
T |
C |
11: 108,752,560 (GRCm38) |
C49R |
probably benign |
Het |
| Clip2 |
G |
A |
5: 134,522,791 (GRCm38) |
T159M |
possibly damaging |
Het |
| Dnah2 |
T |
C |
11: 69,435,884 (GRCm38) |
N3575S |
probably damaging |
Het |
| Dnah6 |
T |
A |
6: 73,067,427 (GRCm38) |
I3234F |
probably damaging |
Het |
| Eci3 |
G |
T |
13: 34,946,978 (GRCm38) |
A302E |
possibly damaging |
Het |
| Fam204a |
T |
C |
19: 60,199,989 (GRCm38) |
K214E |
probably damaging |
Het |
| Fam78a |
T |
C |
2: 32,082,654 (GRCm38) |
T85A |
possibly damaging |
Het |
| Flnb |
T |
C |
14: 7,909,748 (GRCm38) |
Y1401H |
probably damaging |
Het |
| Foxl2 |
A |
T |
9: 98,956,055 (GRCm38) |
D132V |
probably damaging |
Het |
| Frs2 |
C |
A |
10: 117,078,842 (GRCm38) |
W57C |
probably damaging |
Het |
| Gm26558 |
G |
T |
2: 70,661,417 (GRCm38) |
|
probably benign |
Het |
| Gpr139 |
A |
G |
7: 119,144,840 (GRCm38) |
V174A |
probably benign |
Het |
| Grik5 |
T |
C |
7: 25,015,819 (GRCm38) |
T676A |
probably damaging |
Het |
| H60c |
T |
C |
10: 3,259,273 (GRCm38) |
|
probably null |
Het |
| Hspa1l |
A |
G |
17: 34,978,469 (GRCm38) |
K495E |
probably damaging |
Het |
| Irgm1 |
C |
T |
11: 48,866,217 (GRCm38) |
V256I |
probably benign |
Het |
| Kat7 |
T |
A |
11: 95,286,416 (GRCm38) |
T293S |
probably benign |
Het |
| Lipg |
C |
T |
18: 74,960,938 (GRCm38) |
V13I |
probably benign |
Het |
| Lrrn1 |
A |
T |
6: 107,569,224 (GRCm38) |
Y661F |
probably damaging |
Het |
| Mllt3 |
A |
G |
4: 87,840,995 (GRCm38) |
V272A |
probably benign |
Het |
| Mx1 |
G |
A |
16: 97,455,494 (GRCm38) |
R162C |
probably benign |
Het |
| Myo18b |
T |
A |
5: 112,871,470 (GRCm38) |
D647V |
probably damaging |
Het |
| Naf1 |
G |
A |
8: 66,879,646 (GRCm38) |
V329I |
probably benign |
Het |
| Or4k40 |
A |
T |
2: 111,420,774 (GRCm38) |
M59K |
probably damaging |
Het |
| Or52u1 |
A |
T |
7: 104,588,211 (GRCm38) |
I153F |
probably damaging |
Het |
| Or8g22 |
A |
T |
9: 39,046,969 (GRCm38) |
C194* |
probably null |
Het |
| P2rx5 |
G |
A |
11: 73,171,790 (GRCm38) |
V442M |
possibly damaging |
Het |
| Pcdhb9 |
A |
G |
18: 37,401,232 (GRCm38) |
E93G |
probably damaging |
Het |
| Pcdhga4 |
A |
T |
18: 37,687,426 (GRCm38) |
N676I |
probably benign |
Het |
| Pgm5 |
A |
G |
19: 24,820,128 (GRCm38) |
M230T |
probably damaging |
Het |
| Pp2d1 |
T |
C |
17: 53,508,140 (GRCm38) |
M519V |
probably benign |
Het |
| Ppp1r10 |
A |
G |
17: 35,928,511 (GRCm38) |
E404G |
probably damaging |
Het |
| Prpf8 |
A |
T |
11: 75,489,783 (GRCm38) |
E104V |
possibly damaging |
Het |
| Ptpa |
T |
C |
2: 30,438,355 (GRCm38) |
|
probably null |
Het |
| Pygl |
A |
C |
12: 70,201,344 (GRCm38) |
N248K |
probably damaging |
Het |
| Rbm8a |
A |
G |
3: 96,630,932 (GRCm38) |
D102G |
probably damaging |
Het |
| Sema3d |
A |
G |
5: 12,584,908 (GRCm38) |
D647G |
probably benign |
Het |
| Serpinb11 |
A |
T |
1: 107,379,754 (GRCm38) |
D305V |
probably damaging |
Het |
| Slc12a8 |
T |
C |
16: 33,617,208 (GRCm38) |
I337T |
probably damaging |
Het |
| Slc29a2 |
G |
A |
19: 5,028,967 (GRCm38) |
R286Q |
probably benign |
Het |
| Slc2a3 |
T |
A |
6: 122,735,583 (GRCm38) |
D234V |
probably damaging |
Het |
| Slco4a1 |
T |
C |
2: 180,473,108 (GRCm38) |
V608A |
probably damaging |
Het |
| Spata31d1e |
A |
T |
13: 59,743,739 (GRCm38) |
L89H |
probably damaging |
Het |
| Srrm2 |
C |
T |
17: 23,816,587 (GRCm38) |
T831I |
probably benign |
Het |
| St18 |
T |
A |
1: 6,802,317 (GRCm38) |
|
probably null |
Het |
| Tesk2 |
G |
C |
4: 116,741,896 (GRCm38) |
G67A |
probably damaging |
Het |
| Tlr1 |
A |
T |
5: 64,925,221 (GRCm38) |
L671H |
probably damaging |
Het |
| Tmem63b |
A |
T |
17: 45,661,477 (GRCm38) |
Y735N |
possibly damaging |
Het |
| Tmprss11a |
C |
T |
5: 86,420,079 (GRCm38) |
C263Y |
probably damaging |
Het |
| Trio |
A |
T |
15: 27,897,991 (GRCm38) |
V345E |
probably damaging |
Het |
| Tut7 |
A |
G |
13: 59,816,656 (GRCm38) |
|
probably null |
Het |
| Ubr5 |
A |
G |
15: 37,997,916 (GRCm38) |
S1674P |
probably damaging |
Het |
| Uchl3 |
T |
A |
14: 101,695,917 (GRCm38) |
C209S |
probably damaging |
Het |
| Uhmk1 |
T |
C |
1: 170,211,167 (GRCm38) |
N206S |
probably damaging |
Het |
| Uhrf1 |
C |
T |
17: 56,318,340 (GRCm38) |
R588W |
probably damaging |
Het |
| Usp28 |
T |
C |
9: 49,010,250 (GRCm38) |
V256A |
probably damaging |
Het |
| Utrn |
C |
A |
10: 12,728,777 (GRCm38) |
L552F |
probably damaging |
Het |
| Vmn1r55 |
A |
T |
7: 5,146,986 (GRCm38) |
M146K |
probably damaging |
Het |
| Vmn1r57 |
A |
C |
7: 5,221,108 (GRCm38) |
I211L |
probably benign |
Het |
| Zar1 |
C |
T |
5: 72,577,399 (GRCm38) |
C316Y |
probably damaging |
Het |
| Zc3h11a |
A |
T |
1: 133,621,674 (GRCm38) |
S750T |
probably damaging |
Het |
| Zfp366 |
G |
A |
13: 99,246,168 (GRCm38) |
C613Y |
probably benign |
Het |
| Zfp37 |
A |
T |
4: 62,191,256 (GRCm38) |
C524S |
probably damaging |
Het |
| Zfp516 |
T |
C |
18: 82,957,093 (GRCm38) |
V472A |
probably benign |
Het |
| Zhx1 |
A |
T |
15: 58,052,423 (GRCm38) |
M809K |
probably damaging |
Het |
| Zic1 |
T |
C |
9: 91,364,371 (GRCm38) |
Y216C |
probably damaging |
Het |
|
| Other mutations in Pik3c2g |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00159:Pik3c2g
|
APN |
6 |
139,896,125 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01355:Pik3c2g
|
APN |
6 |
139,852,857 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01579:Pik3c2g
|
APN |
6 |
139,754,741 (GRCm38) |
nonsense |
probably null |
|
|
IGL01580:Pik3c2g
|
APN |
6 |
139,622,516 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01587:Pik3c2g
|
APN |
6 |
139,754,741 (GRCm38) |
nonsense |
probably null |
|
|
IGL01813:Pik3c2g
|
APN |
6 |
139,622,409 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
IGL02218:Pik3c2g
|
APN |
6 |
139,860,355 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02479:Pik3c2g
|
APN |
6 |
139,918,004 (GRCm38) |
missense |
probably benign |
0.40 |
|
IGL02480:Pik3c2g
|
APN |
6 |
139,852,800 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02721:Pik3c2g
|
APN |
6 |
139,736,973 (GRCm38) |
missense |
probably benign |
0.15 |
|
IGL02967:Pik3c2g
|
APN |
6 |
139,967,828 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL03221:Pik3c2g
|
APN |
6 |
139,772,407 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
FR4304:Pik3c2g
|
UTSW |
6 |
139,635,656 (GRCm38) |
frame shift |
probably null |
|
|
FR4340:Pik3c2g
|
UTSW |
6 |
139,635,656 (GRCm38) |
frame shift |
probably null |
|
|
FR4976:Pik3c2g
|
UTSW |
6 |
139,635,654 (GRCm38) |
frame shift |
probably null |
|
|
IGL02837:Pik3c2g
|
UTSW |
6 |
139,626,564 (GRCm38) |
nonsense |
probably null |
|
|
PIT4531001:Pik3c2g
|
UTSW |
6 |
139,859,370 (GRCm38) |
missense |
|
|
|
R0002:Pik3c2g
|
UTSW |
6 |
139,768,745 (GRCm38) |
missense |
probably benign |
0.08 |
|
R0081:Pik3c2g
|
UTSW |
6 |
139,957,793 (GRCm38) |
missense |
probably benign |
0.05 |
|
R0098:Pik3c2g
|
UTSW |
6 |
139,662,443 (GRCm38) |
missense |
unknown |
|
|
R0719:Pik3c2g
|
UTSW |
6 |
139,629,725 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0740:Pik3c2g
|
UTSW |
6 |
139,633,793 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0837:Pik3c2g
|
UTSW |
6 |
139,957,699 (GRCm38) |
splice site |
probably benign |
|
|
R0840:Pik3c2g
|
UTSW |
6 |
139,896,072 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1306:Pik3c2g
|
UTSW |
6 |
139,772,428 (GRCm38) |
missense |
probably benign |
|
|
R1501:Pik3c2g
|
UTSW |
6 |
139,844,070 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1591:Pik3c2g
|
UTSW |
6 |
139,748,178 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1666:Pik3c2g
|
UTSW |
6 |
139,635,636 (GRCm38) |
intron |
probably benign |
|
|
R1907:Pik3c2g
|
UTSW |
6 |
139,844,042 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1970:Pik3c2g
|
UTSW |
6 |
139,900,386 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1982:Pik3c2g
|
UTSW |
6 |
139,622,548 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R2171:Pik3c2g
|
UTSW |
6 |
139,855,286 (GRCm38) |
nonsense |
probably null |
|
|
R2188:Pik3c2g
|
UTSW |
6 |
139,852,874 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3777:Pik3c2g
|
UTSW |
6 |
139,622,387 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3778:Pik3c2g
|
UTSW |
6 |
139,622,387 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3965:Pik3c2g
|
UTSW |
6 |
139,855,292 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R4076:Pik3c2g
|
UTSW |
6 |
139,852,863 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4078:Pik3c2g
|
UTSW |
6 |
139,635,610 (GRCm38) |
intron |
probably benign |
|
|
R4108:Pik3c2g
|
UTSW |
6 |
139,730,370 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4461:Pik3c2g
|
UTSW |
6 |
139,841,681 (GRCm38) |
intron |
probably benign |
|
|
R4474:Pik3c2g
|
UTSW |
6 |
139,633,751 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4509:Pik3c2g
|
UTSW |
6 |
139,720,006 (GRCm38) |
missense |
probably benign |
0.25 |
|
R4646:Pik3c2g
|
UTSW |
6 |
139,720,018 (GRCm38) |
missense |
probably benign |
0.05 |
|
R4732:Pik3c2g
|
UTSW |
6 |
139,935,985 (GRCm38) |
missense |
probably benign |
0.28 |
|
R4733:Pik3c2g
|
UTSW |
6 |
139,935,985 (GRCm38) |
missense |
probably benign |
0.28 |
|
R4854:Pik3c2g
|
UTSW |
6 |
139,768,779 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4928:Pik3c2g
|
UTSW |
6 |
139,967,802 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R4959:Pik3c2g
|
UTSW |
6 |
139,843,931 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R4973:Pik3c2g
|
UTSW |
6 |
139,843,931 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R5032:Pik3c2g
|
UTSW |
6 |
139,896,202 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5071:Pik3c2g
|
UTSW |
6 |
139,720,147 (GRCm38) |
missense |
probably null |
0.00 |
|
R5072:Pik3c2g
|
UTSW |
6 |
139,720,147 (GRCm38) |
missense |
probably null |
0.00 |
|
R5073:Pik3c2g
|
UTSW |
6 |
139,720,147 (GRCm38) |
missense |
probably null |
0.00 |
|
R5074:Pik3c2g
|
UTSW |
6 |
139,720,147 (GRCm38) |
missense |
probably null |
0.00 |
|
R5107:Pik3c2g
|
UTSW |
6 |
139,635,625 (GRCm38) |
intron |
probably benign |
|
|
R5253:Pik3c2g
|
UTSW |
6 |
139,896,257 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5359:Pik3c2g
|
UTSW |
6 |
139,622,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5394:Pik3c2g
|
UTSW |
6 |
139,720,082 (GRCm38) |
missense |
probably benign |
|
|
R5417:Pik3c2g
|
UTSW |
6 |
139,736,943 (GRCm38) |
missense |
probably benign |
|
|
R5435:Pik3c2g
|
UTSW |
6 |
139,715,855 (GRCm38) |
splice site |
probably null |
|
|
R5580:Pik3c2g
|
UTSW |
6 |
139,626,533 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5664:Pik3c2g
|
UTSW |
6 |
139,737,007 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5908:Pik3c2g
|
UTSW |
6 |
139,768,710 (GRCm38) |
missense |
|
|
|
R5914:Pik3c2g
|
UTSW |
6 |
139,622,479 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6046:Pik3c2g
|
UTSW |
6 |
139,896,792 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6046:Pik3c2g
|
UTSW |
6 |
139,622,139 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R6298:Pik3c2g
|
UTSW |
6 |
139,626,563 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6382:Pik3c2g
|
UTSW |
6 |
139,719,998 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R6480:Pik3c2g
|
UTSW |
6 |
139,730,469 (GRCm38) |
missense |
probably benign |
0.27 |
|
R6917:Pik3c2g
|
UTSW |
6 |
139,896,173 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6929:Pik3c2g
|
UTSW |
6 |
139,957,776 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R7022:Pik3c2g
|
UTSW |
6 |
139,622,063 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R7144:Pik3c2g
|
UTSW |
6 |
139,629,870 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7213:Pik3c2g
|
UTSW |
6 |
139,860,264 (GRCm38) |
missense |
|
|
|
R7215:Pik3c2g
|
UTSW |
6 |
139,754,863 (GRCm38) |
missense |
|
|
|
R7332:Pik3c2g
|
UTSW |
6 |
139,896,255 (GRCm38) |
missense |
|
|
|
R7357:Pik3c2g
|
UTSW |
6 |
139,633,793 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7359:Pik3c2g
|
UTSW |
6 |
139,967,894 (GRCm38) |
missense |
unknown |
|
|
R7385:Pik3c2g
|
UTSW |
6 |
139,855,353 (GRCm38) |
missense |
|
|
|
R7455:Pik3c2g
|
UTSW |
6 |
139,967,917 (GRCm38) |
missense |
unknown |
|
|
R7651:Pik3c2g
|
UTSW |
6 |
139,622,072 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R7888:Pik3c2g
|
UTSW |
6 |
139,896,744 (GRCm38) |
missense |
|
|
|
R7923:Pik3c2g
|
UTSW |
6 |
139,633,793 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7964:Pik3c2g
|
UTSW |
6 |
139,882,060 (GRCm38) |
missense |
|
|
|
R8005:Pik3c2g
|
UTSW |
6 |
139,622,069 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8371:Pik3c2g
|
UTSW |
6 |
139,936,056 (GRCm38) |
missense |
unknown |
|
|
R8724:Pik3c2g
|
UTSW |
6 |
139,967,893 (GRCm38) |
missense |
unknown |
|
|
R8733:Pik3c2g
|
UTSW |
6 |
139,768,700 (GRCm38) |
nonsense |
probably null |
|
|
R8809:Pik3c2g
|
UTSW |
6 |
139,768,710 (GRCm38) |
missense |
|
|
|
R8888:Pik3c2g
|
UTSW |
6 |
139,730,366 (GRCm38) |
nonsense |
probably null |
|
|
R8931:Pik3c2g
|
UTSW |
6 |
139,875,367 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9188:Pik3c2g
|
UTSW |
6 |
139,622,403 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R9336:Pik3c2g
|
UTSW |
6 |
139,875,435 (GRCm38) |
missense |
|
|
|
R9383:Pik3c2g
|
UTSW |
6 |
139,882,016 (GRCm38) |
nonsense |
probably null |
|
|
R9524:Pik3c2g
|
UTSW |
6 |
139,629,770 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9531:Pik3c2g
|
UTSW |
6 |
139,896,200 (GRCm38) |
missense |
|
|
|
R9630:Pik3c2g
|
UTSW |
6 |
139,622,239 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R9697:Pik3c2g
|
UTSW |
6 |
139,967,791 (GRCm38) |
missense |
unknown |
|
|
R9708:Pik3c2g
|
UTSW |
6 |
139,629,867 (GRCm38) |
missense |
probably benign |
|
|
R9717:Pik3c2g
|
UTSW |
6 |
139,896,184 (GRCm38) |
missense |
|
|
|
RF015:Pik3c2g
|
UTSW |
6 |
139,754,771 (GRCm38) |
missense |
|
|
|
RF032:Pik3c2g
|
UTSW |
6 |
139,635,658 (GRCm38) |
frame shift |
probably null |
|
|
X0024:Pik3c2g
|
UTSW |
6 |
139,860,258 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTGCCTGTGTCACTAAAGACC -3'
(R):5'- TTTCCAAACCGAAGCTGGGAG -3'
Sequencing Primer
(F):5'- CCTGTGTCACTAAAGACCAATTTTTG -3'
(R):5'- TGGGAGGAGTCAGGGCTC -3'
|
| Posted On |
2016-07-06 |
Incidental Mutation