Incidental Mutation 'R7107:Psme4'
| ID |
551261 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Psme4
|
| Ensembl Gene |
ENSMUSG00000040850 |
| Gene Name |
proteasome (prosome, macropain) activator subunit 4 |
| Synonyms |
|
| MMRRC Submission |
045199-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7107 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
30721726-30830361 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 30798105 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Histidine
at position 1366
(R1366H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000045460
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041231]
[ENSMUST00000129824]
|
| AlphaFold |
Q5SSW2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041231
AA Change: R1366H
PolyPhen 2
Score 0.025 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000045460
Gene: ENSMUSG00000040850
AA Change: R1366H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
122 |
133 |
N/A |
INTRINSIC |
|
Pfam:BLM10_mid
|
330 |
828 |
8.8e-119 |
PFAM |
|
SCOP:d1b3ua_
|
1183 |
1716 |
3e-14 |
SMART |
|
Pfam:DUF3437
|
1756 |
1843 |
5.3e-39 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000129824
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
99% (78/79) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele show normal repair of DNA double-strand breaks but exhibit significantly reduced male fertility due to defects in spermatogenesis observed in both meiotic spermatocytes and postmeiotic haploid spermatids. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(25) : Targeted, knock-out(1) Gene trapped(24) |
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca8b |
A |
G |
11: 109,867,299 (GRCm39) |
L253S |
probably damaging |
Het |
| Adgrv1 |
T |
C |
13: 81,726,261 (GRCm39) |
E588G |
probably benign |
Het |
| Ahcy |
G |
A |
2: 154,910,893 (GRCm39) |
A25V |
probably damaging |
Het |
| Ank2 |
A |
C |
3: 126,797,631 (GRCm39) |
L710R |
probably damaging |
Het |
| Ap1b1 |
A |
G |
11: 4,989,558 (GRCm39) |
T824A |
probably benign |
Het |
| Arap2 |
T |
A |
5: 62,763,551 (GRCm39) |
H1531L |
probably damaging |
Het |
| Atosb |
A |
T |
4: 43,036,434 (GRCm39) |
V99E |
probably benign |
Het |
| B3gnt7 |
T |
C |
1: 86,233,495 (GRCm39) |
L247P |
probably damaging |
Het |
| Bcl6b |
A |
G |
11: 70,117,396 (GRCm39) |
C409R |
probably damaging |
Het |
| Bicdl1 |
T |
C |
5: 115,808,229 (GRCm39) |
H301R |
probably benign |
Het |
| Casc3 |
T |
A |
11: 98,718,413 (GRCm39) |
I491N |
possibly damaging |
Het |
| Ccdc92b |
T |
A |
11: 74,520,887 (GRCm39) |
L63Q |
probably damaging |
Het |
| Cep250 |
A |
G |
2: 155,837,314 (GRCm39) |
T2319A |
probably benign |
Het |
| Chd1 |
T |
C |
17: 15,981,628 (GRCm39) |
S1356P |
probably damaging |
Het |
| Chd8 |
A |
G |
14: 52,450,129 (GRCm39) |
S1542P |
probably benign |
Het |
| Clec2m |
A |
G |
6: 129,299,915 (GRCm39) |
C188R |
probably damaging |
Het |
| Cntnap4 |
A |
G |
8: 113,542,120 (GRCm39) |
D751G |
probably damaging |
Het |
| Cpsf4l |
G |
A |
11: 113,593,315 (GRCm39) |
R90C |
possibly damaging |
Het |
| Defa21 |
G |
A |
8: 21,515,724 (GRCm39) |
A41T |
probably damaging |
Het |
| Dennd4a |
G |
T |
9: 64,801,681 (GRCm39) |
L941F |
possibly damaging |
Het |
| Dnah12 |
G |
A |
14: 26,500,869 (GRCm39) |
|
probably null |
Het |
| Dtx4 |
A |
T |
19: 12,450,624 (GRCm39) |
C529* |
probably null |
Het |
| Entpd3 |
A |
G |
9: 120,389,665 (GRCm39) |
Y317C |
probably damaging |
Het |
| Erp29 |
T |
A |
5: 121,583,381 (GRCm39) |
I182F |
possibly damaging |
Het |
| Fam161a |
A |
G |
11: 22,973,452 (GRCm39) |
R445G |
possibly damaging |
Het |
| Fam76a |
T |
A |
4: 132,631,232 (GRCm39) |
M238L |
possibly damaging |
Het |
| Fn1 |
T |
C |
1: 71,666,408 (GRCm39) |
Y875C |
probably damaging |
Het |
| Gnb2 |
A |
G |
5: 137,528,444 (GRCm39) |
|
probably null |
Het |
| Hspg2 |
T |
C |
4: 137,237,963 (GRCm39) |
S229P |
probably damaging |
Het |
| Ighv6-6 |
A |
G |
12: 114,398,590 (GRCm39) |
S59P |
probably damaging |
Het |
| Itpkc |
C |
A |
7: 26,927,702 (GRCm39) |
A71S |
probably benign |
Het |
| Kcnk10 |
G |
A |
12: 98,485,002 (GRCm39) |
R45* |
probably null |
Het |
| Krcc1 |
A |
G |
6: 71,261,198 (GRCm39) |
S77G |
probably benign |
Het |
| Lelp1 |
G |
A |
3: 92,042,821 (GRCm39) |
T76I |
unknown |
Het |
| Lifr |
A |
T |
15: 7,208,421 (GRCm39) |
I600F |
possibly damaging |
Het |
| Lrrk1 |
T |
A |
7: 65,937,191 (GRCm39) |
D987V |
possibly damaging |
Het |
| Muc16 |
C |
T |
9: 18,548,594 (GRCm39) |
D5900N |
probably benign |
Het |
| Muc6 |
AGGCGCAGAAACCCTGGC |
AGGC |
7: 141,214,363 (GRCm39) |
|
probably null |
Het |
| Myo9a |
A |
G |
9: 59,778,098 (GRCm39) |
I1285V |
probably benign |
Het |
| Ndel1 |
T |
C |
11: 68,713,474 (GRCm39) |
D321G |
possibly damaging |
Het |
| Nlrp4b |
T |
C |
7: 10,449,144 (GRCm39) |
V449A |
probably damaging |
Het |
| Or10q12 |
A |
G |
19: 13,746,525 (GRCm39) |
E273G |
probably benign |
Het |
| Or2r11 |
T |
C |
6: 42,437,488 (GRCm39) |
N155S |
possibly damaging |
Het |
| Or2y1c |
T |
A |
11: 49,361,261 (GRCm39) |
Y94* |
probably null |
Het |
| Or51k1 |
A |
T |
7: 103,661,489 (GRCm39) |
L140Q |
probably benign |
Het |
| Or5k3 |
A |
C |
16: 58,969,279 (GRCm39) |
D22A |
probably benign |
Het |
| Osbpl1a |
G |
A |
18: 12,974,310 (GRCm39) |
R459* |
probably null |
Het |
| Pabpc1l |
A |
C |
2: 163,884,399 (GRCm39) |
T379P |
probably damaging |
Het |
| Pde2a |
A |
T |
7: 101,071,175 (GRCm39) |
Q15L |
probably benign |
Het |
| Pdk1 |
A |
G |
2: 71,726,085 (GRCm39) |
N331S |
probably benign |
Het |
| Pfdn1 |
A |
T |
18: 36,584,519 (GRCm39) |
|
probably null |
Het |
| Pnliprp1 |
T |
A |
19: 58,717,582 (GRCm39) |
L9H |
probably damaging |
Het |
| Prl7a2 |
A |
T |
13: 27,843,076 (GRCm39) |
D242E |
possibly damaging |
Het |
| Prmt9 |
T |
A |
8: 78,294,880 (GRCm39) |
I408N |
possibly damaging |
Het |
| Pstpip1 |
A |
T |
9: 56,035,934 (GRCm39) |
D393V |
probably damaging |
Het |
| Rab5b |
A |
G |
10: 128,519,062 (GRCm39) |
|
probably null |
Het |
| Rap1gap2 |
G |
A |
11: 74,283,945 (GRCm39) |
R618C |
probably damaging |
Het |
| Rin1 |
A |
G |
19: 5,100,801 (GRCm39) |
|
probably benign |
Het |
| Sall3 |
G |
A |
18: 81,016,969 (GRCm39) |
P320S |
probably benign |
Het |
| Sdk1 |
A |
G |
5: 142,067,471 (GRCm39) |
T1124A |
probably damaging |
Het |
| Sirpb1c |
T |
A |
3: 15,892,941 (GRCm39) |
T88S |
possibly damaging |
Het |
| Slc35f6 |
T |
A |
5: 30,814,121 (GRCm39) |
I189N |
probably damaging |
Het |
| Slc49a3 |
T |
A |
5: 108,596,581 (GRCm39) |
|
probably null |
Het |
| Spata31d1e |
T |
A |
13: 59,889,997 (GRCm39) |
R608* |
probably null |
Het |
| Spsb2 |
A |
T |
6: 124,787,244 (GRCm39) |
Q226L |
probably benign |
Het |
| Stab2 |
T |
C |
10: 86,741,456 (GRCm39) |
D1221G |
possibly damaging |
Het |
| Sugp1 |
G |
A |
8: 70,522,800 (GRCm39) |
R500H |
probably benign |
Het |
| Syne1 |
A |
G |
10: 5,082,078 (GRCm39) |
Y849H |
probably damaging |
Het |
| Tbck |
T |
A |
3: 132,428,092 (GRCm39) |
I249N |
possibly damaging |
Het |
| Tdrd6 |
A |
C |
17: 43,935,095 (GRCm39) |
F1984L |
probably benign |
Het |
| Tnxb |
T |
A |
17: 34,890,314 (GRCm39) |
V219E |
unknown |
Het |
| Tpst1 |
T |
A |
5: 130,143,344 (GRCm39) |
V294D |
probably damaging |
Het |
| Treml1 |
A |
G |
17: 48,667,247 (GRCm39) |
Q44R |
probably damaging |
Het |
| Trrap |
G |
A |
5: 144,733,945 (GRCm39) |
A933T |
probably benign |
Het |
| Vars2 |
A |
G |
17: 35,969,142 (GRCm39) |
L853P |
probably damaging |
Het |
| Vmn1r10 |
A |
T |
6: 57,090,615 (GRCm39) |
N69I |
possibly damaging |
Het |
| Vmn1r179 |
T |
A |
7: 23,627,819 (GRCm39) |
Y3* |
probably null |
Het |
| Vmn2r38 |
T |
A |
7: 9,093,728 (GRCm39) |
Y498F |
probably benign |
Het |
| Zc3h11a |
T |
C |
1: 133,566,655 (GRCm39) |
T179A |
probably damaging |
Het |
| Zmym2 |
A |
G |
14: 57,140,169 (GRCm39) |
T3A |
probably benign |
Het |
|
| Other mutations in Psme4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00228:Psme4
|
APN |
11 |
30,765,710 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00401:Psme4
|
APN |
11 |
30,771,079 (GRCm39) |
splice site |
probably benign |
|
|
IGL00475:Psme4
|
APN |
11 |
30,795,252 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL00576:Psme4
|
APN |
11 |
30,773,145 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL00817:Psme4
|
APN |
11 |
30,770,129 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01525:Psme4
|
APN |
11 |
30,759,936 (GRCm39) |
splice site |
probably benign |
|
|
IGL01862:Psme4
|
APN |
11 |
30,762,038 (GRCm39) |
nonsense |
probably null |
|
|
IGL02310:Psme4
|
APN |
11 |
30,787,484 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02477:Psme4
|
APN |
11 |
30,792,083 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02545:Psme4
|
APN |
11 |
30,791,586 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL02608:Psme4
|
APN |
11 |
30,770,944 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL02621:Psme4
|
APN |
11 |
30,798,131 (GRCm39) |
missense |
probably benign |
|
|
IGL02822:Psme4
|
APN |
11 |
30,798,204 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02833:Psme4
|
APN |
11 |
30,800,715 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02964:Psme4
|
APN |
11 |
30,741,095 (GRCm39) |
nonsense |
probably null |
|
|
IGL03273:Psme4
|
APN |
11 |
30,798,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03348:Psme4
|
APN |
11 |
30,826,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03382:Psme4
|
APN |
11 |
30,757,788 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
H2330:Psme4
|
UTSW |
11 |
30,801,210 (GRCm39) |
missense |
probably benign |
0.17 |
|
PIT4378001:Psme4
|
UTSW |
11 |
30,771,079 (GRCm39) |
splice site |
probably benign |
|
|
R0276:Psme4
|
UTSW |
11 |
30,761,980 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0462:Psme4
|
UTSW |
11 |
30,798,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0685:Psme4
|
UTSW |
11 |
30,828,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0766:Psme4
|
UTSW |
11 |
30,757,687 (GRCm39) |
splice site |
probably null |
|
|
R0830:Psme4
|
UTSW |
11 |
30,757,797 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0940:Psme4
|
UTSW |
11 |
30,765,264 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1018:Psme4
|
UTSW |
11 |
30,754,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1312:Psme4
|
UTSW |
11 |
30,757,687 (GRCm39) |
splice site |
probably null |
|
|
R1448:Psme4
|
UTSW |
11 |
30,802,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1713:Psme4
|
UTSW |
11 |
30,756,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1732:Psme4
|
UTSW |
11 |
30,798,105 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1813:Psme4
|
UTSW |
11 |
30,754,353 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1905:Psme4
|
UTSW |
11 |
30,760,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1907:Psme4
|
UTSW |
11 |
30,760,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1911:Psme4
|
UTSW |
11 |
30,765,658 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1956:Psme4
|
UTSW |
11 |
30,782,424 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1974:Psme4
|
UTSW |
11 |
30,769,011 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1980:Psme4
|
UTSW |
11 |
30,782,615 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R1986:Psme4
|
UTSW |
11 |
30,780,352 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2046:Psme4
|
UTSW |
11 |
30,767,723 (GRCm39) |
splice site |
probably benign |
|
|
R2142:Psme4
|
UTSW |
11 |
30,770,998 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R2698:Psme4
|
UTSW |
11 |
30,824,282 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2844:Psme4
|
UTSW |
11 |
30,795,173 (GRCm39) |
splice site |
probably benign |
|
|
R3807:Psme4
|
UTSW |
11 |
30,806,027 (GRCm39) |
splice site |
probably null |
|
|
R3876:Psme4
|
UTSW |
11 |
30,806,068 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4420:Psme4
|
UTSW |
11 |
30,762,028 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4584:Psme4
|
UTSW |
11 |
30,784,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4615:Psme4
|
UTSW |
11 |
30,784,287 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4714:Psme4
|
UTSW |
11 |
30,782,573 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5008:Psme4
|
UTSW |
11 |
30,806,896 (GRCm39) |
intron |
probably benign |
|
|
R5109:Psme4
|
UTSW |
11 |
30,741,095 (GRCm39) |
nonsense |
probably null |
|
|
R5155:Psme4
|
UTSW |
11 |
30,826,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5199:Psme4
|
UTSW |
11 |
30,803,272 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5205:Psme4
|
UTSW |
11 |
30,782,666 (GRCm39) |
intron |
probably benign |
|
|
R5452:Psme4
|
UTSW |
11 |
30,741,168 (GRCm39) |
missense |
probably benign |
|
|
R5491:Psme4
|
UTSW |
11 |
30,765,246 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5685:Psme4
|
UTSW |
11 |
30,759,837 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5764:Psme4
|
UTSW |
11 |
30,722,364 (GRCm39) |
intron |
probably benign |
|
|
R5853:Psme4
|
UTSW |
11 |
30,741,234 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5865:Psme4
|
UTSW |
11 |
30,741,993 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5903:Psme4
|
UTSW |
11 |
30,791,589 (GRCm39) |
missense |
probably benign |
0.28 |
|
R5927:Psme4
|
UTSW |
11 |
30,754,294 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6004:Psme4
|
UTSW |
11 |
30,806,896 (GRCm39) |
intron |
probably benign |
|
|
R6102:Psme4
|
UTSW |
11 |
30,815,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6247:Psme4
|
UTSW |
11 |
30,803,245 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6527:Psme4
|
UTSW |
11 |
30,782,175 (GRCm39) |
missense |
probably benign |
|
|
R6750:Psme4
|
UTSW |
11 |
30,803,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6885:Psme4
|
UTSW |
11 |
30,784,307 (GRCm39) |
nonsense |
probably null |
|
|
R6939:Psme4
|
UTSW |
11 |
30,787,291 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6945:Psme4
|
UTSW |
11 |
30,787,437 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7029:Psme4
|
UTSW |
11 |
30,722,474 (GRCm39) |
intron |
probably benign |
|
|
R7049:Psme4
|
UTSW |
11 |
30,763,904 (GRCm39) |
splice site |
probably null |
|
|
R7098:Psme4
|
UTSW |
11 |
30,800,661 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7223:Psme4
|
UTSW |
11 |
30,824,226 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7319:Psme4
|
UTSW |
11 |
30,757,790 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7375:Psme4
|
UTSW |
11 |
30,722,700 (GRCm39) |
splice site |
probably null |
|
|
R7410:Psme4
|
UTSW |
11 |
30,765,279 (GRCm39) |
nonsense |
probably null |
|
|
R7469:Psme4
|
UTSW |
11 |
30,752,837 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7651:Psme4
|
UTSW |
11 |
30,787,334 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7679:Psme4
|
UTSW |
11 |
30,828,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7681:Psme4
|
UTSW |
11 |
30,741,975 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R7822:Psme4
|
UTSW |
11 |
30,824,245 (GRCm39) |
missense |
probably benign |
|
|
R8013:Psme4
|
UTSW |
11 |
30,754,320 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8130:Psme4
|
UTSW |
11 |
30,792,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8323:Psme4
|
UTSW |
11 |
30,793,532 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8330:Psme4
|
UTSW |
11 |
30,793,583 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8363:Psme4
|
UTSW |
11 |
30,762,139 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8491:Psme4
|
UTSW |
11 |
30,722,161 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8690:Psme4
|
UTSW |
11 |
30,787,319 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8696:Psme4
|
UTSW |
11 |
30,759,896 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8743:Psme4
|
UTSW |
11 |
30,828,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8998:Psme4
|
UTSW |
11 |
30,788,957 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9241:Psme4
|
UTSW |
11 |
30,815,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Psme4
|
UTSW |
11 |
30,788,980 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9736:Psme4
|
UTSW |
11 |
30,797,411 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9744:Psme4
|
UTSW |
11 |
30,765,294 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9746:Psme4
|
UTSW |
11 |
30,826,868 (GRCm39) |
nonsense |
probably null |
|
|
V5088:Psme4
|
UTSW |
11 |
30,801,210 (GRCm39) |
missense |
probably benign |
0.17 |
|
X0063:Psme4
|
UTSW |
11 |
30,782,600 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
Z1176:Psme4
|
UTSW |
11 |
30,793,522 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
Z1177:Psme4
|
UTSW |
11 |
30,762,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Psme4
|
UTSW |
11 |
30,756,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATAGTTCATATTGCCATGGCTTAC -3'
(R):5'- AGCTTTCCGAGTCTTGGTATGAC -3'
Sequencing Primer
(F):5'- AGAAGTCCTGAGTTCAGTTCCCAG -3'
(R):5'- CCGAGTCTTGGTATGACTTATGTGAC -3'
|
| Posted On |
2019-05-15 |
Incidental Mutation